SLC30A2 gene related symptoms and diseases
All the information presented here about the SLC30A2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to SLC30A2 gene
| Symptoms // Phenotype | % Cases |
|---|---|
| Alopecia | Very Common - Between 80% and 100% cases |
| Abnormality of the skin | Very Common - Between 80% and 100% cases |
| Eczema | Very Common - Between 80% and 100% cases |
| Inflammatory abnormality of the skin | Very Common - Between 80% and 100% cases |
| Abnormal intestine morphology | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with SLC30A2 gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Abnormality of zinc homeostasis
Rare diseases associated to SLC30A2 gene
Here you will find a list of rare diseases related to the SLC30A2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
ZINC DEFICIENCY, TRANSIENT NEONATAL; TNZD
Alternate names
ZINC DEFICIENCY, TRANSIENT NEONATAL; TNZD Is also known as zinc deficiency, neonatal, due to low breast milk zinc
Description
Transient neonatal zinc deficiency occurs in breast-fed infants as a consequence of low milk zinc concentration in their nursing mothers, which cannot be corrected by maternal zinc supplementation. A large amount of zinc, an essential trace mineral, is required for normal growth particularly in infants, and breast milk normally contains adequate zinc to meet the requirement for infants up to 4 to 6 months of age. Zinc deficiency can lead to dermatitis, alopecia, decreased growth, and impaired immune function. The disorder shows autosomal dominant inheritance with incomplete penetrance (summary by Chowanadisai et al., 2006).Some aspects of TNZD resemble the more severe disorder acrodermatitis enteropathica (AEZ ), an autosomal recessive disorder caused by mutation in the zinc transporter SLC39A4 (OMIM ). However, infants with transient neonatal zinc deficiency do not require zinc supplementation following weaning and have normal zinc absorption, whereas those with AEZ require lifelong zinc supplementation (summary by Chowanadisai et al., 2006).
Most common symptoms of ZINC DEFICIENCY, TRANSIENT NEONATAL; TNZD
- Alopecia
- Abnormality of the skin
- Eczema
- Inflammatory abnormality of the skin
- Abnormal intestine morphology
More info about ZINC DEFICIENCY, TRANSIENT NEONATAL; TNZD
Search interest in SLC30A2
Potential gene panels for SLC30A2 gene
SLC30A2 Sequencing Panel
United States.
By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center
This panel specifically test the SLC30A2 gene.
More info about this panel United States.
SLC30A2. Complete sequencing Panel
Spain.
By Instituto de Medicina Genomica Instituto de Medicina Genomica
This panel specifically test the SLC30A2 gene.
More info about this panel Spain.
Breast milk zinc deficiency: SLC30A2 gene sequence analysis Panel
Spain.
By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases
This panel specifically test the SLC30A2 gene.
More info about this panel Spain.
SLC30A2 Panel
United States.
By Fulgent Genetics Fulgent Genetics
This panel specifically test the SLC30A2 gene.
More info about this panel United States.
Zinc deficiency, transient neonatal Panel
Spain.
By Bioarray
This panel specifically test the SLC30A2 gene.
More info about this panel Spain.
ZINC DEFICIENCY IN BREAST MILK Panel
Spain.
By Laboratorio de Genetica Clinica SL
This panel specifically test the SLC30A2 gene.
More info about this panel Spain.
Zinc Deficiency in Breast Milk , Sequencing SLC30A2 Gene Panel
Spain.
By Reference Laboratory Genetics
This panel specifically test the SLC30A2 gene.
More info about this panel Spain.
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