AFP gene related symptoms and diseases

All the information presented here about the AFP gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to AFP gene

Symptoms // Phenotype % Cases
Decreased levels of alpha-fetoprotein Uncommon - Between 30% and 50% cases
Carcinoma Uncommon - Between 30% and 50% cases
Hepatocellular carcinoma Uncommon - Between 30% and 50% cases
Teratoma Uncommon - Between 30% and 50% cases
Elevated alpha-fetoprotein Uncommon - Between 30% and 50% cases

Rare diseases associated to AFP gene

Here you will find a list of rare diseases related to the AFP. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CONGENITAL DEFICIENCY IN ALPHA-FETOPROTEIN


Description

Congenital deficiency in alpha-fetoprotein is a benign genetic condition characterized by a dramatically decreased level of alpha-fetoprotein in fetus or neonate.

Most common symptoms of CONGENITAL DEFICIENCY IN ALPHA-FETOPROTEIN

  • Decreased levels of alpha-fetoprotein


More info about CONGENITAL DEFICIENCY IN ALPHA-FETOPROTEIN

SOURCES: OMIM MESH ORPHANET

HEREDITARY PERSISTENCE OF ALPHA-FETOPROTEIN


Description

Hereditary persistence of alpha-fetoprotein is a benign genetic condition characterized by persistence of high alpha-fetoprotein (AFP) levels throughout life, with no associated clinical disability and thus no need for specific therapy

Most common symptoms of HEREDITARY PERSISTENCE OF ALPHA-FETOPROTEIN

  • Carcinoma
  • Hepatocellular carcinoma
  • Teratoma
  • Elevated alpha-fetoprotein


More info about HEREDITARY PERSISTENCE OF ALPHA-FETOPROTEIN

SOURCES: OMIM ORPHANET


Potential gene panels for AFP gene

Intellectual Disability NGS Panel Panel

United States.

By Fulgent Genetics Fulgent Genetics Intellectual Disability NGS Panel that also includes the following genes: BCS1L RPS6KA3 SACS BIN1 SCN1A SCN8A SDCCAG8 SGCA SGSH ST3GAL3

More info about this panel

AFP Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the AFP gene.

More info about this panel


If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like GRM8 DLX4 DOCK7 FOXF1

Need help with a diagnosis?

Learn more about how to achieve it with Mendelian


Learn more