Glucagonoma
Description
Glucagonoma is a rare, functioning type of pancreatic neuroendocrine tumor (PNET; see this term) that hypersecretes glucagon, leading to a syndrome comprised of necrolytic migratory erythema, diabetes mellitus, anemia, weight loss, mucosal abnormalities, thromboembolism, gastrointestinal and neuropsychiatric symptoms.
Clinical Features
Top most frequent phenotypes and symptoms related to Glucagonoma
- Hepatomegaly
- Diarrhea
- Depressivity
- Constipation
- Diabetes mellitus
- Weight loss
- Skin rash
- Pruritus
- Nausea and vomiting
- Ascites
And another 32 symptoms. If you need more information about this disease we can help you.
Incidence and onset information
— Based on the latest data available GLUCAGONOMA have a estimated incidence of 0.005 per 100k worldwide.— No data available about the known clinical features onset.
Alternative names
Glucagonoma Is also known as glucagonoma syndrome.
Researches and researchers
Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.Glucagonoma Recommended genes panels
Panel Name, Specifity and genes Tested/covered |
---|
![]() By Baylor Miraca Genetics Laboratories (United States).
RGS9, RHO, GRK1, RLBP1, RNASEL, BCS1L, RP1, RP2, RP9, RPE65, RPGR, RPL35A, MRPL3, RPS14, RS1, SAG, SARDH, SCO2, SCP2, SDHB , (...)
View the complete list with 612 more genes
Specificity
1 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
TP53, VHL, SUFU, PALB2, ALK, APC, MEN1, MLH1, MRE11, MSH2, MSH6, NBN, NF2, ATM, PMS2, PHOX2B, PTCH1
Specificity
6 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
SDHA, SDHB, SDHC, SDHD, TP53, VHL, CDC73, SDHAF2, TMEM127, MAX, MEN1, PRKAR1A, PTEN, RET
Specificity
8 %
Genes
100 % |
![]() By Baylor Miraca Genetics Laboratories (United States).
RUNX1, SDHA, SDHB, SDHC, SDHD, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, VHL, WT1, CBL, SUFU, CDC73, CDH1, CDK4, CDKN1C, CDKN2A , (...)
View the complete list with 39 more genes
Specificity
2 %
Genes
100 % |
![]() By Athena Diagnostics Inc (United States).
MEN1
Specificity
100 %
Genes
100 % |
![]() By Center for Human Genetics, Inc (United States).
MEN1
Specificity
100 %
Genes
100 % |
![]() By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University (United States).
BLM, SDHB, BMPR1A, BRCA1, BRCA2, STK11, EPCAM, TP53, TSC1, TSC2, VHL, XRCC2, CDC73, CDH1, CDK4, CDKN1B, CDKN2A, BRIP1, SDHAF2, TMEM127 , (...)
View the complete list with 28 more genes
Specificity
3 %
Genes
100 % |
You can get up to 143 more panels with our dedicated tool
Learn moreSources and references
You can check the following sources for additional information.
ORPHANET MESH Genetic Syndrome FinderIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SPINOCEREBELLAR ATAXIA, AUTOSOMAL RECESSIVE 10; SCAR10 SPONDYLOCOSTAL DYSOSTOSIS 2, AUTOSOMAL RECESSIVE; SCDO2 PFEIFFER SYNDROME TYPE 1 PERIPHERAL NEUROPATHY, MYOPATHY, HOARSENESS, AND HEARING LOSS; PNMHH EHLERS-DANLOS SYNDROME, CLASSIC TYPE EPISODIC KINESIGENIC DYSKINESIA 1; EKD1 MALIGNANT HYPERTHERMIA, SUSCEPTIBILITY TO, 5