Melanoma, and Proteinuria

Diseases related with Melanoma and Proteinuria

In the following list you will find some of the most common rare diseases related to Melanoma and Proteinuria that can help you solving undiagnosed cases.

Top matches:

Malignant melanoma is a neoplasm of pigment-producing cells called melanocytes that occurs most often in the skin, but may also occur in the eyes, ears, gastrointestinal tract, leptomeninges, and oral and genital mucous membranes (summary by Habif, 2010).For a discussion of genetic heterogeneity of malignant melanoma, see {155600}.

Related symptoms:

  • Neoplasm
  • Melanoma


SOURCES: OMIM MENDELIAN

More info about MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 5; CMM5

Malignant melanoma is a neoplasm of pigment-producing cells called melanocytes that occurs most often in the skin, but may also occur in the eyes, ears, gastrointestinal tract, leptomeninges, and oral and genital mucous membranes (summary by Habif, 2010).For a discussion of genetic heterogeneity of cutaneous malignant melanoma, see {155600}.

Related symptoms:

  • Neoplasm
  • Melanoma


SOURCES: OMIM MENDELIAN

More info about MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 6; CMM6

Other less relevant matches:

MITF-related melanoma and renal cell carcinoma predisposition syndrome is an inherited cancer-predisposing syndrome due to a gain-of-function germline mutation in the MITF gene, associated with a higher incidence of amelanotic and nodular melanoma, multiple primary melanomas and increase in nevus number and size. It may also predispose to co-occurring melanoma and renal cell carcinoma and to pancreatic cancer.

MITF-RELATED MELANOMA AND RENAL CELL CARCINOMA PREDISPOSITION SYNDROME Is also known as melanoma and renal cell carcinoma, susceptibility to

Related symptoms:

  • Neoplasm
  • Melanoma
  • Renal cell carcinoma
  • Cutaneous melanoma


SOURCES: OMIM ORPHANET MENDELIAN

More info about MITF-RELATED MELANOMA AND RENAL CELL CARCINOMA PREDISPOSITION SYNDROME

Lipoprotein glomerulopathy is an uncommon kidney disease characterized by proteinuria, progressive kidney failure, and distinctive lipoprotein thrombi in glomerular capillaries (Saito et al., 2006). It mainly affects people of Japanese and Chinese origin; in these populations, it is associated with mutations in the gene that encodes apolipoprotein E (APOE ). The disorder had rarely been described in Caucasians.

LIPOPROTEIN GLOMERULOPATHY Is also known as lpg

Related symptoms:

  • Edema
  • Renal insufficiency
  • Carcinoma
  • Proteinuria
  • Abnormality of the kidney


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about LIPOPROTEIN GLOMERULOPATHY

Denys-Drash syndrome (DDS) is a rare urogenital disorder characterized by the association of diffuse mesangial sclerosis (DMS), male pseudohermaphroditism with a 46,XY karyotype, and nephroblastoma.

DENYS-DRASH SYNDROME Is also known as drash syndrome|wilms tumor-disorder of sex development syndrome|wilms tumor-dsd syndrome

Related symptoms:

  • Neoplasm
  • Hypertension
  • Edema
  • Renal insufficiency
  • Micropenis


SOURCES: OMIM ORPHANET MENDELIAN

More info about DENYS-DRASH SYNDROME

SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 3; SHEP3 Is also known as skin/hair/eye pigmentation 3, light/dark skin|skin/hair/eye pigmentation 3, freckling|eye color 1|skin/hair/eye pigmentation 3, blue/green eye color|gey|eycl1|eye color, green/blue

Related symptoms:

  • Cutaneous melanoma


SOURCES: OMIM MENDELIAN

More info about SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 3; SHEP3

Malignant melanoma is a neoplasm of pigment-producing cells called melanocytes that occurs most often in the skin, but may also occur in the eyes, ears, gastrointestinal tract, leptomeninges, and oral and genital mucous membranes (summary by Habif, 2010).For a discussion of genetic heterogeneity of cutaneous malignant melanoma, see CMM1 (OMIM ).

Related symptoms:

  • Neoplasm
  • Melanoma
  • Cutaneous melanoma


SOURCES: OMIM MESH MENDELIAN

More info about MELANOMA, CUTANEOUS MALIGNANT, SUSCEPTIBILITY TO, 2; CMM2

Frasier syndrome is characterised by the association of male pseudohermaphrodism and glomerular nephropathy. This syndrome is associated with a high risk of developing gonadoblastoma.

Related symptoms:

  • Neoplasm
  • Hypertension
  • Renal insufficiency
  • Proteinuria
  • Stage 5 chronic kidney disease


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about FRASIER SYNDROME

Karyomegalic interstitial nephritis is a rare, genetic renal disease characterized by slowly progressive, chronic, tubulointerstitial nephritis, leading to end-stage renal disease before the age of 50 years, manifesting with mild proteinuria, glucosuria and, occasionally, urinary sediment abnormalities (mainly hematuria). Mild extrarenal manifestations, such as recurrent upper respiratory tract infections and abnormal liver function tests, may be associated. Renal biopsy reveals severe, chronic, interstitial fibrosis and tubular changes, as well as hallmark karyomegalic tubular epithelial cells which line the proximal and distal tubules and have enlarged, hyperchromatic nuclei.

KARYOMEGALIC INTERSTITIAL NEPHRITIS Is also known as kin|systemic karyomegaly

Related symptoms:

  • Anemia
  • Hypertension
  • Renal insufficiency
  • Recurrent infections
  • Pneumonia


SOURCES: OMIM ORPHANET MENDELIAN

More info about KARYOMEGALIC INTERSTITIAL NEPHRITIS

Top 5 symptoms//phenotypes associated to Melanoma and Proteinuria

Symptoms // Phenotype % cases
Neoplasm Common - Between 50% and 80% cases
Renal insufficiency Uncommon - Between 30% and 50% cases
Stage 5 chronic kidney disease Uncommon - Between 30% and 50% cases
Hypertension Uncommon - Between 30% and 50% cases
Cutaneous melanoma Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Melanoma and Proteinuria. may also develop some of the following symptoms:

Rare Symptoms - Less than 30% cases

Carcinoma Edema Male pseudohermaphroditism Gonadal dysgenesis Focal segmental glomerulosclerosis Nephroblastoma Nephrotic syndrome Gonadoblastoma Renal cell carcinoma Glomerulopathy Nephropathy Abnormality of the kidney Respiratory tract infection Elevated hepatic transaminase Hematuria Cholestasis Chronic kidney disease Pneumonia Abnormality of the liver Elevated serum creatinine Nephritis Nephronophthisis Glycosuria Tubulointerstitial nephritis Anemia Tubular atrophy Normocytic anemia Increased blood urea nitrogen Mild proteinuria Recurrent infections Amenorrhea Ovarian gonadoblastoma Diffuse mesangial sclerosis Hyperlipoproteinemia Mesangial hypercellularity Micropenis Ambiguous genitalia Abnormality of the genital system Abnormality of the genitourinary system Glomerulosclerosis Steroid-resistant nephrotic syndrome Gonadal dysgenesis with female appearance, male Primary amenorrhea Hypergonadotropic hypogonadism Increased circulating gonadotropin level Sex reversal Decreased serum estradiol Ambiguous genitalia, male Streak ovary Chronic tubulointerstitial nephritis


If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like Arthritis and Hypoglycemia, related diseases and genetic alterations