Lymphoma, and Migraine

Diseases related with Lymphoma and Migraine

In the following list you will find some of the most common rare diseases related to Lymphoma and Migraine that can help you solving undiagnosed cases.

Top matches:

Classic Hodgkin lymphoma is a lymph node cancer of germinal center B-cell origin. Hodgkin lymphoma tumors consist of a minority of malignant cells, known as 'Reed-Sternberg' (RS) cells, mixed with reactive lymphocytes and other benign inflammatory cells. A defining feature of RS cells is the presence of 2 nuclei (summary by Salipante et al., 2009).

LYMPHOMA, HODGKIN, CLASSIC; CHL Is also known as hodgkin disease

Related symptoms:

  • Ataxia
  • Neoplasm
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


SOURCES: OMIM ORPHANET MENDELIAN

More info about LYMPHOMA, HODGKIN, CLASSIC; CHL

Waldenström macroglobulinemia (WM) is an indolent B-cell lymphoproliferative disorder characterized by the accumulation of monoclonal cells in the bone marrow and peripheral lymphoid tissues, and associated with the production of serum immunoglobulin M (IgM) monoclonal protein.

Related symptoms:

  • Hearing impairment
  • Ataxia
  • Neoplasm
  • Anemia
  • Peripheral neuropathy


SOURCES: OMIM ORPHANET MENDELIAN

More info about WALDENSTRÖM MACROGLOBULINEMIA

Schimke immuno-osseous dysplasia (SIOD) is a multisystem disorder characterized by spondyloepiphyseal dysplasia and disproportionate short stature, facial dysmorphism, T-cell immunodeficiency, and glomerulonephritis with nephrotic syndrome.

SCHIMKE IMMUNO-OSSEOUS DYSPLASIA Is also known as immunoosseous dysplasia, schimke type|schimke syndrome|spondyloepiphyseal dysplasia-nephrotic syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Scoliosis
  • Growth delay


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about SCHIMKE IMMUNO-OSSEOUS DYSPLASIA

Other less relevant matches:

Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN, see this term) characterized by a sustained elevation of platelet number (> 450 x 109/L) with a tendency for thrombosis and hemorrhage.

ESSENTIAL THROMBOCYTHEMIA Is also known as thrombocytosis 1|essential thrombocytosis|et

Related symptoms:

  • Pain
  • Hypertension
  • Hepatomegaly
  • Abnormality of the skeletal system
  • Respiratory distress


SOURCES: ORPHANET OMIM MENDELIAN

More info about ESSENTIAL THROMBOCYTHEMIA

Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases. The retinoblastoma gene (RB1) was the first tumor suppressor gene cloned. It is a negative regulator of the cell cycle through its ability to bind the transcription factor E2F (OMIM ) and repress transcription of genes required for S phase (Hanahan and Weinberg, 2000).

RETINOBLASTOMA; RB1 Is also known as rb

Related symptoms:

  • Intellectual disability
  • Hearing impairment
  • Microcephaly
  • Nystagmus
  • Neoplasm


SOURCES: OMIM ORPHANET MENDELIAN

More info about RETINOBLASTOMA; RB1

Deafness - lymphedema - leukemia is a very rare, serious syndromic genetic disorder characterized by primary lymphedema, immunodeficiency, and hematological disorders.

DEAFNESS-LYMPHEDEMA-LEUKEMIA SYNDROME Is also known as emberger syndrome

Related symptoms:

  • Hearing impairment
  • Neoplasm
  • Sensorineural hearing impairment
  • Anemia
  • Epicanthus


SOURCES: OMIM ORPHANET MENDELIAN

More info about DEAFNESS-LYMPHEDEMA-LEUKEMIA SYNDROME

Blackfan-Diamond anemia (DBA) is a congenital aregenerative and often macrocytic anemia with erythroblastopenia.

BLACKFAN-DIAMOND ANEMIA Is also known as congenital hypoplastic anemia, blackfan-diamond type|congenital pure red cell aplasia|aase-smith syndrome ii|congenital prca|aase-smith ii syndrome|aase syndrome

Related symptoms:

  • Short stature
  • Growth delay
  • Hypertelorism
  • Neoplasm
  • Failure to thrive


SOURCES: ORPHANET OMIM MENDELIAN

More info about BLACKFAN-DIAMOND ANEMIA

Familial amyloid polyneuropathy (FAP) or transthyretin (TTR) amyloid polyneuropathy is a progressive sensorimotor and autonomic neuropathy of adulthood onset. Weight loss and cardiac involvement are frequent; ocular or renal complications may also occur.

ATTRV30M AMYLOIDOSIS Is also known as familial amyloid polyneuropathy type i|ttr amyloid neuropathy|attrv30m-related amyloidosis|hereditary amyloidosis, transthyretin-related|transthyretin amyloid polyneuropathy|familial amyloid polyneuropathy, portuguese-swedish-japanese type|fap|amyloid pol

Related symptoms:

  • Seizures
  • Hearing impairment
  • Ataxia
  • Nystagmus
  • Sensorineural hearing impairment


SOURCES: OMIM ORPHANET MENDELIAN

More info about ATTRV30M AMYLOIDOSIS

Neurofibromatosis type I is an autosomal dominant disorder characterized by cafe-au-lait spots, Lisch nodules in the eye, and fibromatous tumors of the skin. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors. NF1 is sometimes referred to as 'peripheral neurofibromatosis.' The worldwide incidence of NF1 is 1 in 2,500 to 1 in 3,000 individuals (reviews by Shen et al., 1996 and Williams et al., 2009).Type II neurofibromatosis (NF2 ) is a genetically distinct disorder caused by mutation in the gene encoding merlin (NF2 ) on chromosome 22q12. NF2, sometimes known as 'central neurofibromatosis,' is characterized by bilateral acoustic neuroma and meningioma, but few skin lesions or neurofibromas (Rouleau et al., 1993).Some patients with homozygous or compound heterozygous mutations in mismatch repair genes (see, e.g., MLH1; {120436} and MSH2; {609309}) have a phenotype characterized by early onset malignancies and mild features of NF1, especially cafe-au-lait spots; this is known as the mismatch repair cancer syndrome (OMIM ), sometimes referred to as brain tumor-polyposis syndrome-1 or Turcot syndrome. These patients typically do not have germline mutations in the NF1 gene, although a study by Wang et al. (2003) suggested that biallelic mutations in mismatch repair genes may cause somatic mutations in the NF1 gene, perhaps resulting in isolated features resembling NF1.See also Legius syndrome (OMIM ), a genetically distinct disorder with a similar phenotype to NF1.

NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION Is also known as von recklinghausen disease due to nf1 mutation or intragenic deletion|neurofibromatosis, peripheral type|von recklinghausen disease

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Scoliosis
  • Hypertelorism


SOURCES: ORPHANET OMIM MENDELIAN

More info about NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION

Low match COWDEN SYNDROME

Cowden syndrome (CS) is a difficult to recognize, under-diagnosed genodermatosis characterized by the presence of multiple hamartomas in various tissues and an increased risk for malignancies of the breast, thyroid, endometrium, kidney and colorectum. When CS is accompanied by germline PTEN mutations, it belongs to the PTEN hamartoma tumor syndrome (PHTS; see this term) group.

COWDEN SYNDROME Is also known as bzs|cowden disease|bbrs|macrocephaly, multiple lipomas, and hemangiomata|pten hamartoma tumor syndrome with granular cell tumor|bannayan-zonana syndrome|macrocephaly, pseudopapilledema, and multiple hemangiomata|cs|cd|mham|pten hamartoma tumor syndrome|ri

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


SOURCES: ORPHANET OMIM MENDELIAN

More info about COWDEN SYNDROME

Top 5 symptoms//phenotypes associated to Lymphoma and Migraine

Symptoms // Phenotype % cases
Neoplasm Common - Between 50% and 80% cases
Leukemia Common - Between 50% and 80% cases
Headache Common - Between 50% and 80% cases
Anemia Common - Between 50% and 80% cases
Weight loss Common - Between 50% and 80% cases

Other less frequent symptoms

Patients with Lymphoma and Migraine. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Fever Hearing impairment Pain Ataxia Intellectual disability Seizures Short stature Diarrhea Malabsorption Recurrent infections Hydrocephalus Visual loss Splenomegaly Respiratory insufficiency Fatigue Hepatomegaly Peripheral neuropathy Astrocytoma Acute myeloid leukemia Autism Cellulitis Hypertension Visual impairment Scoliosis Abnormal facial shape Cognitive impairment Acute leukemia Cardiomyopathy Vomiting Immunodeficiency Myelodysplasia Paresthesia Multiple cafe-au-lait spots Vertigo Hypertelorism Abnormality of skin pigmentation Congestive heart failure Bone marrow hypocellularity Cellular immunodeficiency Anorexia Lymphadenopathy Renal insufficiency Pallor

Rare Symptoms - Less than 30% cases

Atherosclerosis Gliosis Neutropenia Myeloproliferative disorder Cafe-au-lait spot Abnormal cerebellum morphology Gangrene Myeloid leukemia Breast carcinoma Prolonged bleeding time Leukocytosis Incoordination Reduced bone mineral density Venous thrombosis Bruising susceptibility Lymphopenia Cleft palate Renal cell carcinoma Abnormality of the skeletal system Meningioma Transient ischemic attack Abnormality of the vasculature Neoplasm of the central nervous system Melanocytic nevus Nystagmus Mitral valve prolapse Overgrowth Leiomyosarcoma Tetralogy of Fallot Autistic behavior Osteoporosis Arrhythmia Atrial septal defect Micrognathia Failure to thrive Nephropathy Muscle weakness Nausea and vomiting Sensorineural hearing impairment Soft tissue sarcoma Dysarthria Dilatation Neurofibromas Sarcoma Increased intracranial pressure Carcinoma Glaucoma Blindness Tremor Peripheral axonal neuropathy Delayed speech and language development Macrocephaly Intellectual disability, mild Melanoma Cataract Intracranial hemorrhage Hypercoagulability Gastrointestinal hemorrhage Osteopenia Hodgkin lymphoma Myopia Skin rash Abnormality of the kidney Stroke Polyneuropathy Intrauterine growth retardation Vasculitis Growth delay Cerebellar atrophy Kyphosis Thrombocytopenia Cranial nerve paralysis Dementia Hypothyroidism Bone pain Chest pain Cutis marmorata Motor delay Autoimmunity Scarring Polyclonal elevation of IgM Lymphoproliferative disorder Monoclonal immunoglobulin M proteinemia Impaired lymphocyte transformation with phytohemagglutinin Pruritus Proptosis Complete atrioventricular canal defect Sensory axonal neuropathy Hyperhidrosis Pulmonary fibrosis Gastrointestinal stroma tumor Fibular bowing Paraganglioma Hypophosphatemia Dural ectasia Freckling Epigastric pain Clitoral hypertrophy Pseudoarthrosis Precocious puberty Back pain Single ventricle Renal artery stenosis Tibial bowing Osteomalacia Pheochromocytoma Night sweats Parathyroid adenoma Aqueductal stenosis Brain neoplasm Rhabdomyosarcoma Myocardial fibrosis Neoplasm of the endocrine system Anomalous pulmonary venous return Nasolacrimal duct obstruction Cough Increased reactive oxygen species production Glioma Schwannoma Renal phosphate wasting Overweight Severe vision loss Carcinoid tumor Lisch nodules Chronic myelogenous leukemia Coarctation of aorta Spina bifida Restrictive cardiomyopathy Vitreous floaters Orthostatic hypotension due to autonomic dysfunction Psychomotor deterioration Urinary retention Sensory ataxia Abnormal renal physiology Myelopathy Constrictive median neuropathy Stroke-like episode Multiple myeloma Increased CSF protein Amyloid deposition in the vitreous humor Syringomyelia Amyloidosis Decreased number of peripheral myelinated nerve fibers Orthostatic hypotension Axonal degeneration Aphasia Malnutrition Impotence Cerebral hemorrhage Rheumatoid arthritis Cardiac amyloidosis Ptosis Sensorimotor neuropathy Attention deficit hyperactivity disorder Aganglionic megacolon Hypsarrhythmia Axillary freckling Abnormality of the cardiovascular system Osteolysis Specific learning disability Recurrent fractures Facial asymmetry Genu valgum Pulmonic stenosis Paralysis Lung adenocarcinoma Hypertrophic cardiomyopathy Hypoglycemia Kyphoscoliosis Hyperactivity Abnormal heart morphology Depressivity Abnormality of cardiovascular system morphology Hemoptysis Behavioral abnormality Poor appetite Renovascular hypertension Bulbous nose Embryonal rhabdomyosarcoma Ovarian cyst Decreased proportion of CD4-positive T cells Generalized hyperkeratosis Fibroma Hamartomatous polyposis Papilloma Enlarged polycystic ovaries Cavernous hemangioma Long penis Bone cyst Intestinal polyposis Abnormality of the uterus Colonic diverticula Furrowed tongue Arteriovenous malformation Hydrocele testis Megalencephaly Skin tags Prolactin excess Papilledema Lipoma Scaphocephaly Hashimoto thyroiditis Thyroiditis Adenoma sebaceum Subcutaneous lipoma Hyperthyroidism Transitional cell carcinoma of the bladder Multiple trichilemmomata Merkel cell skin cancer Ductal carcinoma in situ Conjunctival hamartoma Dysplastic gangliocytoma of the cerebellum Trichilemmoma Enlarged cerebellum Cutis marmorata telangiectatica congenita Fibroadenoma of the breast Neoplasm of the thyroid gland Acrokeratosis Abnormality of the penis Mucosal telangiectasiae Pseudopapilledema Progressive macrocephaly Colorectal polyposis Endometrial carcinoma Follicular thyroid carcinoma Varicocele Thyroid adenoma Intestinal polyp Ovarian carcinoma Angioid streaks of the fundus Ovarian neoplasm Hamartoma Vestibular Schwannoma Brow ptosis Pectus excavatum Myopathy Frontal bossing Downslanted palpebral fissures Skeletal muscle atrophy Brachydactyly High palate Low-set ears Generalized hypotonia Global developmental delay Tibial pseudoarthrosis Proximal muscle weakness Cerebral artery stenosis Arterial fibromuscular dysplasia Spinal neurofibromas Inguinal freckling Plexiform neurofibroma Acute promyelocytic leukemia Atrioventricular block Subcutaneous neurofibromas Optic nerve glioma Neurofibrosarcoma Neuroma Narrow mouth Intellectual disability, moderate Cystic hygroma Gynecomastia Multiple lipomas Abnormality of the thyroid gland Macule Hand polydactyly Dysdiadochokinesis Palmoplantar hyperkeratosis Goiter Hypopigmented skin patches Hemangioma Drooling Neoplasm of the skin Exotropia Papule Chronic diarrhea Telangiectasia Subcutaneous nodule Broad thumb Intention tremor Decreased antibody level in blood Macroglossia Hypoplasia of the maxilla Palmoplantar keratoderma Polymicrogyria Joint hypermobility Cachexia Paraplegia Spastic paraparesis Lateral displacement of the femoral head Thrombocytosis Pulmonary embolism Abnormality of the dentition Pneumonia Myocardial infarction Hepatosplenomegaly Dyspnea Respiratory distress Thin upper lip vermilion Nephrosclerosis Short neck Anterior pituitary dysgenesis Premature arteriosclerosis Moyamoya phenomenon Abnormal immunoglobulin level Abnormal T cell morphology Encephalomalacia Increased thyroid-stimulating hormone level Shallow acetabular fossae Steroid-resistant nephrotic syndrome Multiple lentigines Acrocyanosis Abnormality of the cerebral vasculature Hypoplasia of the capital femoral epiphysis Strabismus Reduced consciousness/confusion Periorbital edema Postural instability Normocytic anemia Abnormality of neutrophils Malar flattening Retinal hemorrhage Multifocal epileptiform discharges Cryoglobulinemia Depressed nasal bridge Microcephaly Arterial thrombosis Increased megakaryocyte count Abnormal platelet aggregation Decreased mean platelet volume Abnormal platelet morphology Bloody diarrhea Myelofibrosis Abnormality of bone marrow cell morphology Amaurosis fugax Impaired platelet aggregation Abnormal thrombocyte morphology Mucopolysacchariduria Arteriosclerosis Uveitis Abnormal lung morphology Chronic kidney disease Coarse hair Azoospermia Hyperlipidemia Corneal opacity Opacification of the corneal stroma Hip dislocation Abnormality of epiphysis morphology Heterotopia Abnormal form of the vertebral bodies Fine hair Glomerulosclerosis Intellectual disability, profound Lumbar hyperlordosis Nephrotic syndrome Microdontia Decreased testicular size Waddling gait Premature birth Brain atrophy Platyspondyly Astigmatism Encephalitis Epiphyseal dysplasia Right ventricular cardiomyopathy Protuberant abdomen Dentinogenesis imperfecta Subvalvular aortic stenosis Precocious atherosclerosis Cerebral ischemia Villous atrophy B-cell lymphoma Disproportionate short-trunk short stature Ovoid vertebral bodies Thoracic kyphosis Proteinuria Glomerulopathy Glomerulonephritis Developmental regression Steatorrhea Hypermelanotic macule Combined immunodeficiency High pitched voice Emphysema Focal segmental glomerulosclerosis Spondyloepiphyseal dysplasia Hyperlordosis Nephritis Abnormality of the retinal vasculature Chromosome breakage Paraparesis Delayed puberty Abnormality of the hand Abnormality of the urinary system Short thumb Abnormality of the genital system Mitral regurgitation Depressed nasal ridge Thick lower lip vermilion Ventricular hypertrophy Bifid uvula Cleft upper lip Cleft lip Macrocytic anemia Retrognathia Memory impairment Epistaxis Patent ductus arteriosus Short nose Purpura Ventricular septal defect Urticaria Pleural effusion Abnormal neutrophil count Triphalangeal thumb Tracheomalacia Erysipelas Stage 5 chronic kidney disease Abnormal autonomic nervous system physiology Hallucinations Hemiparesis Cardiomegaly Bilateral sensorineural hearing impairment Peripheral demyelination Neuronal loss in central nervous system Hypotension Urinary incontinence Coma Facial palsy Esophagitis Arthritis Constipation Hyporeflexia Areflexia Spasticity Persistence of hemoglobin F Fetal distress Reticulocytopenia Cleft soft palate Increased mean corpuscular volume Macronodular cirrhosis Granulocytopenia Osteosarcoma Leukocoria Hyphema Neoplasm of the eye Sebaceous gland carcinoma Liposarcoma Histiocytoma Vitritis Burkitt lymphoma Fibrosarcoma Glioblastoma multiforme Malar rash Pulmonary infiltrates Pineal cyst Raynaud phenomenon Anisocoria Ocular pain Vitreous hemorrhage Retinoblastoma Inflammatory abnormality of the eye Buphthalmos Edema of the lower limbs Acute monocytic leukemia Anemia of inadequate production Ewing sarcoma Iris neovascularization Abnormality of the optic nerve Cirrhosis Verrucae Chronic otitis media Leukopenia Lymphedema Pancytopenia Hypotelorism Webbed neck Tapered finger Hematuria Hemolytic anemia Elevated erythrocyte sedimentation rate Pinealoma Neurological speech impairment Respiratory failure Recurrent respiratory infections Syndactyly Edema Epicanthus Gingival bleeding Neuroblastic tumors Pineoblastoma Retinal calcification Lobular carcinoma in situ


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