Lymphoma, and Hypodontia

Diseases related with Lymphoma and Hypodontia

In the following list you will find some of the most common rare diseases related to Lymphoma and Hypodontia that can help you solving undiagnosed cases.

Top matches:

Medium match EEC SYNDROME

EEC syndrome is a genetic developmental disorder characterized by ectrodactyly, ectodermal dysplasia, and orofacial clefts (cleft lip/palate).

EEC SYNDROME Is also known as eec syndrome 3|ectrodactyly-ectodermal dysplasia-cleft lip/palate syndrome

Related symptoms:

  • Intellectual disability
  • Short stature
  • Hearing impairment
  • Sensorineural hearing impairment
  • Cleft palate


SOURCES: OMIM ORPHANET MENDELIAN

More info about EEC SYNDROME

Dyskeratosis congenita (DC) is a rare ectodermal dysplasia that often presents with the classic triad of nail dysplasia, skin pigmentary changes, and oral leukoplakia associated with a high risk of bone marrow failure (BMF) and cancer.

DYSKERATOSIS CONGENITA Is also known as dkc|dc|dyskeratosis congenita, scoggins type|zinsser-engman-cole syndrome

Related symptoms:

  • Global developmental delay
  • Short stature
  • Hearing impairment
  • Microcephaly
  • Scoliosis


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about DYSKERATOSIS CONGENITA

Bone marrow failure syndrome-3 is an autosomal recessive disorder characterized by onset of pancytopenia in early childhood. Patients may have additional variable nonspecific somatic abnormalities, including poor growth, microcephaly, and skin anomalies (summary by Tummala et al., 2016).For a discussion of genetic heterogeneity of BMFS, see BMFS1 (OMIM ).

Related symptoms:

  • Short stature
  • Microcephaly
  • Growth delay
  • Neoplasm
  • Visual impairment


SOURCES: OMIM MENDELIAN

More info about BONE MARROW FAILURE SYNDROME 3; BMFS3

Other less relevant matches:

Ellis-van Creveld syndrome (EVC) is a skeletal and ectoderlam dysplasia characterized by a tetrad of short stature, postaxial polydactyly, ectodermal dysplasia, and congenital heart defects.

ELLIS VAN CREVELD SYNDROME Is also known as mesodermic dysplasia|mesoectodermal dysplasia|chondroectodermal dysplasia

Related symptoms:

  • Intellectual disability
  • Short stature
  • Growth delay
  • Failure to thrive
  • Strabismus


SOURCES: OMIM ORPHANET MENDELIAN

More info about ELLIS VAN CREVELD SYNDROME

SOTOS SYNDROME 1; SOTOS1 Is also known as chromosome 5q35 deletion syndrome|sotos syndrome|cerebral gigantism

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Hearing impairment


SOURCES: OMIM MENDELIAN

More info about SOTOS SYNDROME 1; SOTOS1

Low match CHIME SYNDROME

CHIME syndrome is a rare ectodermal dysplasia syndrome characterized by ocular colobomas, cardiac defects, ichthyosiform dermatosis, intellectual disability, conductive hearing loss and epilepsy.

CHIME SYNDROME Is also known as coloboma-congenital heart disease-ichthyosiform dermatosis-intellectual disability-ear anomalies syndrome|zunich-kaye syndrome|zunich neuroectodermal syndrome|neuroectodermal syndrome, zunich type|chime syndrome|gpibd5|pigl-cdg|neuroectodermal dysplasia,

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about CHIME SYNDROME

Schöpf-Schulz-Passarge syndrome (SSPS) is a rare autosomal recessive ectodermal dysplasia characterized by multiple eyelid apocrine hidrocystomas, palmoplantar keratoderma, hypotrichosis, hypodontia and nail dystrophy.

SCHÖPF-SCHULZ-PASSARGE SYNDROME Is also known as palmoplantar keratoderma-cystic eyelids-hypodontia-hypotrichosis syndrome|keratosis palmoplantaris with cystic eyelids, hypodontia, and hypotrichosis|eccrine tumors with ectodermal dysplasia|ssps|palmoplantar hyperkeratosis-cystic eyelids-hypodontia-hypot

Related symptoms:

  • Neoplasm
  • Alopecia
  • Hyperhidrosis
  • Hyperkeratosis
  • Carcinoma


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about SCHÖPF-SCHULZ-PASSARGE SYNDROME

Tooth agenesis in some form is a common human anomaly that affects approximately 20% of the population. Although tooth agenesis is associated with numerous syndromes, several case reports describe nonsyndromic forms that are either sporadic or familial in nature, as reviewed by Gorlin et al. (1990). The incidence of familial tooth agenesis varies with each class of teeth. Most commonly affected are third molars (wisdom teeth), followed by either upper lateral incisors or lower second premolars; agenesis involving first and second molars is very rare. Also see {114600} and {302400}.Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth). Faulty use of the terms, however, have confounded their use. The term 'partial anodontia' is obsolete (Salinas, 1978). Genetic Heterogeneity of Selective Tooth AgenesisOther forms of selective tooth agenesis include STHAG2 (OMIM ), mapped to chromosome 16q12; STHAG3 (OMIM ), caused by mutation in the PAX9 gene (OMIM ) on chromosome 14q12; STHAG4 (OMIM ), caused by mutation in the WNT10A gene (OMIM ) on chromosome 2q35; STHAG5 (OMIM ), mapped to chromosome 10q11; STHAG7 (OMIM ), caused by mutation in the LRP6 gene (OMIM ) on chromosome 12p13; STHAG8 (OMIM ), caused by mutation in the WNT10B gene (OMIM ) on chromosome 12q13; STHAG9 (OMIM ), caused by mutation in the GREM2 gene (OMIM ) on chromosome 1q43; and STHAGX1 (OMIM ), caused by mutation in the EDA gene (OMIM ) on chromosome Xq13.A type of selective tooth agenesis that was formerly designated STHAG6 has been incorporated into the dental anomalies and short stature syndrome (DASS ).Of 34 unrelated patients with nonsyndromic tooth agenesis, van den Boogaard et al. (2012) found that 56% (19 patients) had mutations in the WNT10A gene (STHAG4), whereas only 3% and 9% had mutations in the MSX1 (STHAG1) and PAX9 (STHAG3) genes, respectively. The authors concluded that WNT10A is a major gene in the etiology of isolated hypodontia. Genotype-Phenotype CorrelationsYu et al. (2016) observed that the most frequently missing permanent teeth in WNT10B-associated oligodontia were the lateral incisors (83.3%), whereas premolars were missing only 51.4% of the time, which they noted was a pattern 'clearly different' from the oligodontia patterns resulting from WNT10A mutations. They also stated that the selective pattern in WNT10B mutants was different from that associated with mutations in other genes, such as MSX1, in which second premolars are missing, and PAX9, in which there is agenesis of molars.

TOOTH AGENESIS, SELECTIVE, 1; STHAG1 Is also known as hyd1|hypodontia/oligodontia 1|second premolars and third molars, absence of|tooth agenesis, familial

Related symptoms:

  • Short stature
  • Abnormality of the dentition
  • Hypodontia
  • Oligodontia
  • Reduced number of teeth


SOURCES: OMIM MENDELIAN

More info about TOOTH AGENESIS, SELECTIVE, 1; STHAG1

PRIMARY FAILURE OF TOOTH ERUPTION Is also known as posterior openbite malocclusion, familial|unerupted second primary molar|dental noneruption|pfe|primary failure of eruption, nonsyndromic|primary retention of teeth

Related symptoms:

  • Abnormality of the dentition
  • Hypodontia
  • Open bite
  • Agenesis of permanent teeth
  • Increased number of teeth


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about PRIMARY FAILURE OF TOOTH ERUPTION

Van der Woude syndrome (VWS) is a rare congenital genetic dysmorphic syndrome characterized by paramedian lower-lip fistulae, cleft lip with or without cleft palate, or isolated cleft palate.

VAN DER WOUDE SYNDROME Is also known as cleft lip/palate with mucous cysts of lower lip|lip-pit syndrome|vws

Related symptoms:

  • Cleft palate
  • Cleft upper lip
  • Hypodontia
  • Abnormal salivary gland morphology
  • Lip pit


SOURCES: ORPHANET MENDELIAN

More info about VAN DER WOUDE SYNDROME

Top 5 symptoms//phenotypes associated to Lymphoma and Hypodontia

Symptoms // Phenotype % cases
Short stature Common - Between 50% and 80% cases
Abnormality of the dentition Uncommon - Between 30% and 50% cases
Hyperkeratosis Uncommon - Between 30% and 50% cases
Leukemia Uncommon - Between 30% and 50% cases
Nail dystrophy Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Lymphoma and Hypodontia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Ectodermal dysplasia Intellectual disability Neoplasm Microdontia Hearing impairment Cleft palate Cleft upper lip Growth delay Strabismus Agenesis of permanent teeth Ventricular septal defect Taurodontia Renal agenesis Reduced number of teeth Global developmental delay Abnormal heart morphology Abnormality of the kidney Intrauterine growth retardation Cryptorchidism Sparse hair

Rare Symptoms - Less than 30% cases

Abnormality of skin pigmentation Alopecia Microcephaly Hypotrichosis Scoliosis Nail dysplasia Nail pits Duplicated collecting system Thin nail Urethral stenosis Selective tooth agenesis Palmoplantar hyperkeratosis Aplasia/Hypoplasia of the nipples Palmoplantar keratoderma Large hands Pancytopenia Atrial septal defect Seizures Generalized hypotonia Hypertelorism Heterotopia Frontal bossing Prominent forehead Genu valgum Conductive hearing impairment Carcinoma Skin ulcer Small nail Tall stature Abnormal dermatoglyphics Abnormality of female internal genitalia Ridged nail Acute lymphoblastic leukemia Long foot Abnormality of the fingernails Bone marrow hypocellularity Increased number of teeth Hyperhidrosis Acute leukemia Polydactyly Aplasia/Hypoplasia of the skin Hydroureter Keratitis Hypoplastic toenails Hypospadias Renal hypoplasia/aplasia Abnormality of dental enamel Hypoplastic nipples Hydronephrosis Hypoplasia of dental enamel Carious teeth Fine hair Hypoplasia of the maxilla Vesicoureteral reflux Depressed nasal bridge Blepharitis Otitis media Apocrine hidrocystoma Clumsiness Abnormal oral mucosa morphology Apraxia Sloping forehead Overgrowth High, narrow palate Abnormal vertebral morphology Joint hypermobility Hypermetropia Dolichocephaly Respiratory tract infection Joint laxity Neonatal short-limb short stature Lymphedema Cone-shaped epiphyses of phalanges 2 to 5 Aggressive behavior Horizontal ribs Epispadias Neuroblastoma Prolonged neonatal jaundice Partial agenesis of the corpus callosum Bird-like facies Nephroblastoma Abnormality of primary teeth Narrow face Precocious puberty Redundant skin Cutis laxa Narrow nail Accelerated skeletal maturation Narrow palate Pointed chin Poroma Oligodontia Abnormal salivary gland morphology High palate Downslanted palpebral fissures Unerupted tooth Optic atrophy Macrocephaly Hyperreflexia Delayed speech and language development Abnormal facial shape Ventriculomegaly Nystagmus Congenital megaureter Abnormality of dental eruption Lip pit Short iliac bones Acetabular spurs Abnormality of the alveolar ridges Failure of eruption of permanent teeth Behavioral abnormality Anodontia Persistence of primary teeth Open bite Ankylosis Abnormality of bone marrow cell morphology Neonatal hypotonia Jaundice Pes planus Poor coordination Capitate-hamate fusion Macrotia Common atrium Multiple impacted teeth Mandibular prognathia Abnormal oral frenulum morphology Conical incisor Patent ductus arteriosus Coarse facial features Aplasia/Hypoplasia of the phalanges of the hand High anterior hairline Thick vermilion border Broad-based gait Depressed nasal ridge Thick lower lip vermilion Tetralogy of Fallot Webbed neck Bifid uvula Short foot Short palm Joint contracture of the hand Low-set nipples Abnormality of the eye Ichthyosis Squamous cell carcinoma Aplasia/Hypoplasia of the eyebrow Hip dislocation Corneal opacity Abnormality of epiphysis morphology Osteolysis Ovarian neoplasm Large for gestational age Aplastic clavicle Ureteropelvic junction obstruction Peripheral pulmonary artery stenosis Retinal coloboma Pulmonary valve atresia Transposition of the great arteries Decreased fertility Abnormality of dental morphology Widely spaced teeth Erythroderma Overfolded helix Brittle hair Growth abnormality Violent behavior Recurrent skin infections Abnormality of the outer ear Aplasia/Hypoplasia of the phalanges of the toes Basal cell carcinoma Short philtrum Enlarged cisterna magna Expressive language delay Ptosis Trichodysplasia Muscular hypotonia Abnormality of the cerebral ventricles Small cell lung carcinoma Gray matter heterotopias Sacrococcygeal teratoma Hyperplasia of the maxilla Feeding difficulties Teratoma Hamartomatous polyposis Overbite Abnormal glucose tolerance Clubbing of toes Oxycephaly Cavum septum pellucidum Advanced eruption of teeth Facial telangiectasia Epicanthus Coloboma Cerebral cortical atrophy Wide mouth Renal cell carcinoma Erythema Camptodactyly Abnormal hair quantity Abnormality of the nervous system Autism Onycholysis Plantar hyperkeratosis Brachycephaly Upslanted palpebral fissure Premature loss of primary teeth Clinodactyly of the 5th finger Toenail dysplasia Cerebral atrophy Wide nasal bridge Brachydactyly Periventricular leukomalacia Postaxial polydactyly Thoracic dysplasia Dacryocystitis Periorbital hyperpigmentation Transverse vaginal septum Mesoaxial polydactyly Abnormality of the inner ear Aplasia/Hypoplasia of the breasts Megacystis Urethral atresia Ureterocele Absence of Stensen duct Abnormality of the middle ear Abnormality of the nasopharynx Central diabetes insipidus Inflammatory abnormality of the eye Bladder diverticulum Slow-growing hair Entropion Lacrimation abnormality Generalized microdontia Ataxia Hypoplasia of the thymus Malabsorption Hepatic fibrosis Hyperpigmentation of the skin Cerebral calcification Specific learning disability Abnormal blistering of the skin Recurrent fractures Hepatic failure Cirrhosis Diabetes mellitus Cataract Osteoporosis Recurrent respiratory infections Cerebellar hypoplasia Thrombocytopenia Immunodeficiency Splenomegaly Hepatomegaly Anemia Anterior hypopituitarism Sparse pubic hair Abnormal intestine morphology Microtia Sparse scalp hair Growth hormone deficiency Nevus Thick eyebrow Oral cleft Dry skin Toe syndactyly Finger syndactyly Blepharophimosis Split hand Cleft lip Photophobia Micropenis Dilatation Syndactyly Malar flattening Flexion contracture Sensorineural hearing impairment Choanal atresia Renal dysplasia Dysuria External ear malformation Sparse axillary hair Generalized hypopigmentation Corneal erosion Fair hair Blue irides Depressed nasal tip Split foot Xerostomia Ectrodactyly Recurrent urinary tract infections Aplasia/Hypoplasia of the thumb Proximal placement of thumb Coarse hair Cutaneous syndactyly Sparse eyelashes Hypogonadotrophic hypogonadism Sparse and thin eyebrow Hypohidrosis Lymphopenia Neoplasm of the skin Hypoplastic iliac wing Micromelia Abnormality of the hair Situs inversus totalis Postaxial hand polydactyly Limb undergrowth Dandy-Walker malformation Delayed eruption of teeth Short distal phalanx of finger Thin vermilion border Narrow chest Abnormality of the nail Pectus carinatum Skeletal dysplasia Severe short stature Delayed skeletal maturation Abnormality of cardiovascular system morphology Talipes equinovarus Abnormality of the skeletal system Failure to thrive Short ribs Short long bone Acute myeloid leukemia Disproportionate short stature Aplasia/Hypoplasia of the lungs Postaxial foot polydactyly Upper limb undergrowth Foot polydactyly Synostosis of carpal bones Abnormality of the ureter Natal tooth Abnormal heart valve morphology Atrioventricular canal defect Abnormality of pelvic girdle bone morphology Short thorax Thoracic hypoplasia Hypoplastic left heart Dextrocardia Emphysema Mild short stature Cubitus valgus Hand polydactyly Chromosome breakage Myeloid leukemia Hypopigmented skin patches Macule Periodontitis Abnormal eyebrow morphology Neoplasm of the pancreas Abnormal eyelash morphology Premature loss of teeth Aseptic necrosis Telangiectasia of the skin Skin vesicle Neurofibromas Abnormality of the testis Hypermelanotic macule Abnormality of coagulation Premature graying of hair Pulmonary fibrosis Epiphora Tracheoesophageal fistula Myelodysplasia Dermal atrophy White hair Oral leukoplakia Retinal dystrophy Reticular hyperpigmentation Dysphagia Visual impairment Absent lacrimal punctum Esophageal stenosis Palmar hyperkeratosis Displacement of the external urethral meatus Congenital bullous ichthyosiform erythroderma Anorectal anomaly Rough bone trabeculation Aplastic anemia Porokeratosis Aplastic/hypoplastic toenail Interstitial pneumonitis Abnormality of neutrophils Squamous cell carcinoma of the skin Abnormality of the pharynx Testicular atrophy Cellular immunodeficiency Lower lip pit


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