Lymphoma, and Headache

Diseases related with Lymphoma and Headache

In the following list you will find some of the most common rare diseases related to Lymphoma and Headache that can help you solving undiagnosed cases.

Top matches:

Classic Hodgkin lymphoma is a lymph node cancer of germinal center B-cell origin. Hodgkin lymphoma tumors consist of a minority of malignant cells, known as 'Reed-Sternberg' (RS) cells, mixed with reactive lymphocytes and other benign inflammatory cells. A defining feature of RS cells is the presence of 2 nuclei (summary by Salipante et al., 2009).

LYMPHOMA, HODGKIN, CLASSIC; CHL Is also known as hodgkin disease

Related symptoms:

  • Ataxia
  • Neoplasm
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


SOURCES: OMIM ORPHANET MENDELIAN

More info about LYMPHOMA, HODGKIN, CLASSIC; CHL

Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN, see this term) characterized by a sustained elevation of platelet number (> 450 x 109/L) with a tendency for thrombosis and hemorrhage.

ESSENTIAL THROMBOCYTHEMIA Is also known as thrombocytosis 1|essential thrombocytosis|et

Related symptoms:

  • Pain
  • Hypertension
  • Hepatomegaly
  • Abnormality of the skeletal system
  • Respiratory distress


SOURCES: ORPHANET OMIM MENDELIAN

More info about ESSENTIAL THROMBOCYTHEMIA

Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases. The retinoblastoma gene (RB1) was the first tumor suppressor gene cloned. It is a negative regulator of the cell cycle through its ability to bind the transcription factor E2F (OMIM ) and repress transcription of genes required for S phase (Hanahan and Weinberg, 2000).

RETINOBLASTOMA; RB1 Is also known as rb

Related symptoms:

  • Intellectual disability
  • Hearing impairment
  • Microcephaly
  • Nystagmus
  • Neoplasm


SOURCES: OMIM ORPHANET MENDELIAN

More info about RETINOBLASTOMA; RB1

Other less relevant matches:

Waldenström macroglobulinemia (WM) is an indolent B-cell lymphoproliferative disorder characterized by the accumulation of monoclonal cells in the bone marrow and peripheral lymphoid tissues, and associated with the production of serum immunoglobulin M (IgM) monoclonal protein.

Related symptoms:

  • Hearing impairment
  • Ataxia
  • Neoplasm
  • Anemia
  • Peripheral neuropathy


SOURCES: OMIM ORPHANET MENDELIAN

More info about WALDENSTRÖM MACROGLOBULINEMIA

Schimke immuno-osseous dysplasia (SIOD) is a multisystem disorder characterized by spondyloepiphyseal dysplasia and disproportionate short stature, facial dysmorphism, T-cell immunodeficiency, and glomerulonephritis with nephrotic syndrome.

SCHIMKE IMMUNO-OSSEOUS DYSPLASIA Is also known as immunoosseous dysplasia, schimke type|schimke syndrome|spondyloepiphyseal dysplasia-nephrotic syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Scoliosis
  • Growth delay


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about SCHIMKE IMMUNO-OSSEOUS DYSPLASIA

Neurofibromatosis type I is an autosomal dominant disorder characterized by cafe-au-lait spots, Lisch nodules in the eye, and fibromatous tumors of the skin. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors. NF1 is sometimes referred to as 'peripheral neurofibromatosis.' The worldwide incidence of NF1 is 1 in 2,500 to 1 in 3,000 individuals (reviews by Shen et al., 1996 and Williams et al., 2009).Type II neurofibromatosis (NF2 ) is a genetically distinct disorder caused by mutation in the gene encoding merlin (NF2 ) on chromosome 22q12. NF2, sometimes known as 'central neurofibromatosis,' is characterized by bilateral acoustic neuroma and meningioma, but few skin lesions or neurofibromas (Rouleau et al., 1993).Some patients with homozygous or compound heterozygous mutations in mismatch repair genes (see, e.g., MLH1; {120436} and MSH2; {609309}) have a phenotype characterized by early onset malignancies and mild features of NF1, especially cafe-au-lait spots; this is known as the mismatch repair cancer syndrome (OMIM ), sometimes referred to as brain tumor-polyposis syndrome-1 or Turcot syndrome. These patients typically do not have germline mutations in the NF1 gene, although a study by Wang et al. (2003) suggested that biallelic mutations in mismatch repair genes may cause somatic mutations in the NF1 gene, perhaps resulting in isolated features resembling NF1.See also Legius syndrome (OMIM ), a genetically distinct disorder with a similar phenotype to NF1.

NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION Is also known as von recklinghausen disease due to nf1 mutation or intragenic deletion|neurofibromatosis, peripheral type|von recklinghausen disease

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Scoliosis
  • Hypertelorism


SOURCES: ORPHANET OMIM MENDELIAN

More info about NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION

Low match COWDEN SYNDROME

Cowden syndrome (CS) is a difficult to recognize, under-diagnosed genodermatosis characterized by the presence of multiple hamartomas in various tissues and an increased risk for malignancies of the breast, thyroid, endometrium, kidney and colorectum. When CS is accompanied by germline PTEN mutations, it belongs to the PTEN hamartoma tumor syndrome (PHTS; see this term) group.

COWDEN SYNDROME Is also known as bzs|cowden disease|bbrs|macrocephaly, multiple lipomas, and hemangiomata|pten hamartoma tumor syndrome with granular cell tumor|bannayan-zonana syndrome|macrocephaly, pseudopapilledema, and multiple hemangiomata|cs|cd|mham|pten hamartoma tumor syndrome|ri

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


SOURCES: ORPHANET OMIM MENDELIAN

More info about COWDEN SYNDROME

Low match FANCONI ANEMIA

Fanconi anemia (FA) is a hereditary DNA repair disorder characterized by progressive pancytopenia with bone marrow failure, variable congenital malformations and predisposition to develop hematological or solid tumors.

FANCONI ANEMIA Is also known as fanconi pancytopenia|fanconi anemia|fa

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Hearing impairment
  • Microcephaly


SOURCES: OMIM ORPHANET MENDELIAN

More info about FANCONI ANEMIA

Both familial and sporadic pituitary adenomas have been found to be caused by germline mutation in the CDH23 gene. Familial pituitary adenoma types include growth hormone (GH)-secreting and nonfunctional tumors. Sporadic pituitary adenoma types include GH-secreting, nonfunctional, prolactin (PRL)-secreting, adrenocorticotropin (ACTH)-secreting, thyroid-stimulating hormone (TSH)-secreting, and plurihormonal (GH and TSH) tumors.For a general description and a discussion of genetic heterogeneity of pituitary adenomas, see PITA1 (OMIM ).

Related symptoms:

  • Neoplasm
  • Headache
  • Pituitary adenoma


SOURCES: OMIM MENDELIAN

More info about PITUITARY ADENOMA 5, MULTIPLE TYPES; PITA5

Primary familial polycythemia is an inherited hematological disorder resulting from mutations in the erythropoietin (EPO) receptor and is characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production in the presence of low EPO levels.

PRIMARY FAMILIAL POLYCYTHEMIA Is also known as polycythemia, primary familial and congenital|primary familial and congenital polycythemia|familial erythrocytosis|erythrocytosis, autosomal dominant benign|pfcp|congenital polycythemia due to erythropoietin receptor mutation|congenital erythrocytosis due

Related symptoms:

  • Pain
  • Hypertension
  • Fatigue
  • Respiratory distress
  • Splenomegaly


SOURCES: OMIM ORPHANET MENDELIAN

More info about PRIMARY FAMILIAL POLYCYTHEMIA

Top 5 symptoms//phenotypes associated to Lymphoma and Headache

Symptoms // Phenotype % cases
Leukemia Common - Between 50% and 80% cases
Neoplasm Common - Between 50% and 80% cases
Intellectual disability Uncommon - Between 30% and 50% cases
Pain Uncommon - Between 30% and 50% cases
Weight loss Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Lymphoma and Headache. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Anemia Vertigo Multiple cafe-au-lait spots Hearing impairment Hypertension Abnormal facial shape Hydrocephalus Scoliosis Ataxia Short stature Splenomegaly Hepatomegaly Fever Fatigue Abnormality of skin pigmentation Proptosis Abnormality of the kidney Hypertelorism Renal insufficiency Acute myeloid leukemia Reduced bone mineral density Cognitive impairment Diarrhea Recurrent infections Carcinoma Visual loss Stroke Malabsorption Seizures Cranial nerve paralysis Visual impairment Astrocytoma Hypothyroidism Cataract Congestive heart failure Myelodysplasia Venous thrombosis Abnormality of the skeletal system Bone marrow hypocellularity Respiratory distress Anorexia Cafe-au-lait spot Pruritus Migraine Cellular immunodeficiency Peripheral neuropathy Respiratory insufficiency

Rare Symptoms - Less than 30% cases

Myopia Immunodeficiency Failure to thrive Kyphosis Micrognathia High palate Cardiomyopathy Autoimmunity Intrauterine growth retardation Hypopigmented skin patches Cutis marmorata Frontal bossing Abnormality of the uterus Growth delay Thrombocytopenia Atrial septal defect Arteriovenous malformation Telangiectasia Lymphoproliferative disorder Gastrointestinal hemorrhage Epistaxis Motor delay Neoplasm of the central nervous system Global developmental delay Melanocytic nevus Facial asymmetry Hypertrophic cardiomyopathy Autism Abnormal heart morphology Abnormality of cardiovascular system morphology Dilatation Intellectual disability, mild Macrocephaly Delayed speech and language development Aganglionic megacolon B-cell lymphoma Abnormality of the vasculature Spina bifida Overgrowth Azoospermia Atherosclerosis Lymphopenia Abnormal cerebellum morphology Neutropenia Breast carcinoma Astigmatism Hip dislocation Incoordination Osteopenia Renal cell carcinoma Meningioma Ptosis Tetralogy of Fallot Vomiting Sarcoma Transient ischemic attack Nystagmus Cough Acute monocytic leukemia Myeloid leukemia Monoclonal immunoglobulin M proteinemia Impaired lymphocyte transformation with phytohemagglutinin Chromosome breakage Cellulitis Neurofibromas Increased intracranial pressure Gangrene Glaucoma Myocardial infarction Skin rash Blindness Cleft palate Polyclonal elevation of IgM Dyspnea Strabismus Microcephaly Paresthesia Lymphadenopathy Bruising susceptibility Leiomyosarcoma Hodgkin lymphoma Chest pain Soft tissue sarcoma Bone pain Varicocele Fibroadenoma of the breast Cutis marmorata telangiectatica congenita Intestinal polyposis Ovarian cyst Hyperhidrosis Furrowed tongue Enlarged cerebellum Trichilemmoma Neoplasm of the thyroid gland Hydrocele testis Megalencephaly Dysplastic gangliocytoma of the cerebellum Conjunctival hamartoma Ductal carcinoma in situ Merkel cell skin cancer Multiple trichilemmomata Skin tags Lobular carcinoma in situ Bone cyst Transitional cell carcinoma of the bladder Long penis Progressive macrocephaly Intestinal polyp Ovarian carcinoma Follicular thyroid carcinoma Endometrial carcinoma Angioid streaks of the fundus Colorectal polyposis Abnormality of the penis Subcutaneous lipoma Colonic diverticula Pseudopapilledema Thyroid adenoma Decreased proportion of CD4-positive T cells Generalized hyperkeratosis Fibroma Mucosal telangiectasiae Hamartomatous polyposis Papilloma Enlarged polycystic ovaries Cavernous hemangioma Acrokeratosis Adenoma sebaceum Fibrosarcoma Prolactin excess Proximal muscle weakness Intention tremor Decreased antibody level in blood Macroglossia Hypoplasia of the maxilla Palmoplantar keratoderma Polymicrogyria Joint hypermobility Nausea and vomiting Papule Intellectual disability, moderate Narrow mouth Subcutaneous nodule Pectus excavatum Myopathy Tremor Downslanted palpebral fissures Skeletal muscle atrophy Brachydactyly Osteolysis Low-set ears Muscle weakness Hemoptysis Broad thumb Chronic diarrhea Papilledema Abnormality of the thyroid gland Lipoma Scaphocephaly Epicanthus Hashimoto thyroiditis Thyroiditis Ovarian neoplasm Hyperthyroidism Hamartoma Cystic hygroma Multiple lipomas Macule Exotropia Hand polydactyly Intracranial hemorrhage Dysdiadochokinesis Palmoplantar hyperkeratosis Goiter Melanoma Hemangioma Drooling Neoplasm of the skin Gynecomastia Cryptorchidism Hypogonadism Hyperreflexia Abnormal aortic morphology Decreased fertility in males Clubbing of toes Partial duplication of thumb phalanx Complete duplication of thumb phalanx Aplasia/Hypoplasia of the iris Low-grade fever Meckel diverticulum Duplicated collecting system Duodenal stenosis Primary hypothyroidism Abnormality of nervous system morphology Reticulocytopenia Hypoplastic anemia Abnormality of chromosome stability Abnormal localization of kidney Abnormal renal morphology Abnormal aortic valve morphology Abnormality of the hypothalamus-pituitary axis Abnormality of femur morphology Bicornuate uterus Abnormality of the thumb Abnormality of the testis Aplastic anemia Abnormality of the upper limb Chromosomal breakage induced by crosslinking agents Absent testis Abnormal eyelid morphology Arthralgia Increased red blood cell mass Plethora Increased hematocrit Increased hemoglobin Abnormal hemoglobin Thromboembolism Polycythemia Exertional dyspnea Cerebral hemorrhage Abnormal bleeding Myalgia Abdominal pain Compensated hypothyroidism Pituitary adenoma Abnormality of the preputium Pyridoxine-responsive sideroblastic anemia Aplasia/Hypoplasia of fingers Aplasia/Hypoplasia of the uvula Neoplasm of head and neck Deficient excision of UV-induced pyrimidine dimers in DNA Anemic pallor Prolonged G2 phase of cell cycle Abnormal carotid artery morphology Almond-shaped palpebral fissure Abnormality of the ulna Hearing abnormality Ventriculomegaly Postnatal growth retardation Sloping forehead Renal agenesis Hypopigmentation of the skin Anal atresia Abnormality of the foot Toe syndactyly Dolichocephaly Finger syndactyly Small for gestational age Abnormal cardiac septum morphology Abnormality of the liver Irritability Pancytopenia Abnormality of the eye Pes planus Umbilical hernia Diabetes mellitus Upslanted palpebral fissure Poor appetite Severe short stature Clinodactyly of the 5th finger Patent ductus arteriosus Hypospadias Microphthalmia Oligohydramnios Short palpebral fissure External ear malformation Triphalangeal thumb Irregular hyperpigmentation Aplasia/Hypoplasia of the radius Absent radius Abnormality of blood and blood-forming tissues Absent thumb Hydroureter Ectopic kidney Squamous cell carcinoma Hypoplasia of the ulna Glucose intolerance Tracheoesophageal fistula Hyperinsulinemia Choanal atresia Abnormality of the urinary system Abnormality of vision Renal hypoplasia/aplasia Leukopenia Type I diabetes mellitus Horseshoe kidney Hypergonadotropic hypogonadism Abnormal vertebral morphology Insulin resistance Short thumb Recurrent urinary tract infections Abnormality of the genital system Generalized hypotonia Vestibular Schwannoma Brow ptosis Gliosis Abnormal lung morphology Fine hair Intellectual disability, profound Lumbar hyperlordosis Nephrotic syndrome Microdontia Decreased testicular size Waddling gait Premature birth Brain atrophy Abnormal platelet aggregation Heterotopia Increased megakaryocyte count Nephropathy Bulbous nose Stage 5 chronic kidney disease Platyspondyly Corneal opacity Scarring Hyperlordosis Developmental regression Proteinuria Thin upper lip vermilion Abnormal form of the vertebral bodies Abnormality of epiphysis morphology Pneumonia Abnormality of bone marrow cell morphology Protuberant abdomen Glomerulopathy Amaurosis fugax Steatorrhea Hypermelanotic macule Combined immunodeficiency High pitched voice Emphysema Focal segmental glomerulosclerosis Spondyloepiphyseal dysplasia Nephritis Decreased mean platelet volume Glomerulonephritis Epiphyseal dysplasia Glomerulosclerosis Encephalitis Chronic kidney disease Coarse hair Myelofibrosis Bloody diarrhea Hyperlipidemia Abnormal platelet morphology Opacification of the corneal stroma Dementia Malar flattening Thoracic kyphosis Neuroblastic tumors Retinoblastoma Memory impairment Vitreous hemorrhage Polyneuropathy Ocular pain Anisocoria Pallor Leukocoria Malar rash Glioblastoma multiforme Pineoblastoma Purpura Retinal calcification Pinealoma Iris neovascularization Pineal cyst Ewing sarcoma Hyphema Neoplasm of the eye Sebaceous gland carcinoma Liposarcoma Histiocytoma Vitritis Vasculitis Inflammatory abnormality of the eye Abnormality of the dentition Abnormality of neutrophils Cerebellar atrophy Postural instability Short neck Depressed nasal bridge Uveitis Osteosarcoma Anemia of inadequate production Cryoglobulinemia Multifocal epileptiform discharges Retinal hemorrhage Normocytic anemia Urticaria Periorbital edema Reduced consciousness/confusion Abnormality of the retinal vasculature Hypercoagulability Edema of the lower limbs Raynaud phenomenon Pulmonary infiltrates Gingival bleeding Elevated erythrocyte sedimentation rate Buphthalmos Pleural effusion Myeloproliferative disorder Ovoid vertebral bodies Tibial pseudoarthrosis Brain neoplasm Nasolacrimal duct obstruction Rhabdomyosarcoma Carcinoid tumor Paraganglioma Night sweats Anomalous pulmonary venous return Complete atrioventricular canal defect Pheochromocytoma Parathyroid adenoma Aqueductal stenosis Myocardial fibrosis Schwannoma Neoplasm of the endocrine system Increased reactive oxygen species production Overweight Severe vision loss Osteomalacia Freckling Tibial bowing Pulmonary fibrosis Hypophosphatemia Sensory axonal neuropathy Clitoral hypertrophy Glioma Renal phosphate wasting Back pain Burkitt lymphoma Cerebral artery stenosis Arterial fibromuscular dysplasia Spinal neurofibromas Inguinal freckling Plexiform neurofibroma Acute promyelocytic leukemia Subcutaneous neurofibromas Optic nerve glioma Neurofibrosarcoma Neuroma Embryonal rhabdomyosarcoma Chronic myelogenous leukemia Axillary freckling Renovascular hypertension Renal artery stenosis Single ventricle Pseudoarthrosis Epigastric pain Dural ectasia Fibular bowing Gastrointestinal stroma tumor Lung adenocarcinoma Lisch nodules Precocious puberty Hepatosplenomegaly Disproportionate short-trunk short stature Shallow acetabular fossae Abnormal thrombocyte morphology Lateral displacement of the femoral head Nephrosclerosis Anterior pituitary dysgenesis Premature arteriosclerosis Moyamoya phenomenon Abnormal immunoglobulin level Abnormal T cell morphology Encephalomalacia Increased thyroid-stimulating hormone level Steroid-resistant nephrotic syndrome Abnormality of the cerebral vasculature Multiple lentigines Mucopolysacchariduria Hypoplasia of the capital femoral epiphysis Arteriosclerosis Right ventricular cardiomyopathy Dentinogenesis imperfecta Subvalvular aortic stenosis Precocious atherosclerosis Cerebral ischemia Villous atrophy Impaired platelet aggregation Arterial thrombosis Dysarthria Sensorimotor neuropathy Pulmonic stenosis Hypsarrhythmia Coarctation of aorta Mitral valve prolapse Abnormality of the cardiovascular system Leukocytosis Specific learning disability Recurrent fractures Peripheral axonal neuropathy Prolonged bleeding time Genu valgum Attention deficit hyperactivity disorder Acute leukemia Paralysis Autistic behavior Hypoglycemia Kyphoscoliosis Pulmonary embolism Hyperactivity Osteoporosis Thrombocytosis Depressivity Acrocyanosis Behavioral abnormality Peripheral thrombosis


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