Lymphoma, and Gynecomastia

Diseases related with Lymphoma and Gynecomastia

In the following list you will find some of the most common rare diseases related to Lymphoma and Gynecomastia that can help you solving undiagnosed cases.


Top matches:

Medium match COWDEN SYNDROME


Cowden syndrome (CS) is a difficult to recognize, under-diagnosed genodermatosis characterized by the presence of multiple hamartomas in various tissues and an increased risk for malignancies of the breast, thyroid, endometrium, kidney and colorectum. When CS is accompanied by germline PTEN mutations, it belongs to the PTEN hamartoma tumor syndrome (PHTS; see this term) group.

COWDEN SYNDROME Is also known as bzs|cowden disease|bbrs|macrocephaly, multiple lipomas, and hemangiomata|pten hamartoma tumor syndrome with granular cell tumor|bannayan-zonana syndrome|macrocephaly, pseudopapilledema, and multiple hemangiomata|cs|cd|mham|pten hamartoma tumor syndrome|ri

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


SOURCES: ORPHANET OMIM MENDELIAN

More info about COWDEN SYNDROME

Medium match PEUTZ-JEGHERS SYNDROME; PJS


Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by melanocytic macules of the lips, buccal mucosa, and digits; multiple gastrointestinal hamartomatous polyps; and an increased risk of various neoplasms.

PEUTZ-JEGHERS SYNDROME; PJS Is also known as polyps-and-spots syndrome|polyposis, hamartomatous intestinal

Related symptoms:

  • Neoplasm
  • Hypertension
  • Edema
  • Diarrhea
  • Headache


SOURCES: OMIM MENDELIAN

More info about PEUTZ-JEGHERS SYNDROME; PJS

Low match COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5; HNPCC5


Hereditary nonpolyposis colorectal cancer type 5 is a cancer predisposition syndrome characterized by onset of colorectal cancer and/or extracolonic cancers, particularly endometrial cancer, usually in mid-adulthood. The disorder shows autosomal dominant inheritance with incomplete penetrance (summary by Castellsague et al., 2015).For a phenotypic description and a discussion of genetic heterogeneity of hereditary nonpolyposis colorectal cancer (HNPCC), see HNPCC1 (OMIM ).

Related symptoms:

  • Neoplasm
  • Carcinoma
  • Lymphoma
  • Breast carcinoma
  • Colon cancer


SOURCES: MESH OMIM MENDELIAN

More info about COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5; HNPCC5

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Other less relevant matches:

Low match HYPERPLASTIC POLYPOSIS SYNDROME


Hyperplastic polyposis syndrome is a rare, genetic intestinal disease characterized by the presence of multiple (usually large) hyperplastic/serrated colorectal polyps, usually with a pancolonic distribution. Histology reveals hyperplastic polyps, sessile serrated adenomas (most common), traditional serrated adenomas or mixed polyps. It is associated with an increased personal and familial (first-degree relatives) risk of colorectal cancer.

HYPERPLASTIC POLYPOSIS SYNDROME Is also known as serrated polyposis

Related symptoms:


SOURCES: ORPHANET MENDELIAN

More info about HYPERPLASTIC POLYPOSIS SYNDROME

Low match NTHL1-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS


Familial adenomatous polyposis-3 is an autosomal recessive cancer predisposition syndrome characterized by the development of multiple colonic adenomas, often with progression to colorectal cancer. Carcinomas affecting other tissues may also occur, and the carcinomas tend to develop in middle age or late adulthood (summary by Weren et al., 2015).For a discussion of genetic heterogeneity of familial adenomatous polyposis, see FAP1 (OMIM ).

NTHL1-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS Is also known as nthl1-related attenuated fap|nthl1-related afap

Related symptoms:

  • Neoplasm
  • Carcinoma
  • Nevus
  • Lymphoma
  • Neoplasm of the skin


SOURCES: OMIM ORPHANET MENDELIAN

More info about NTHL1-RELATED ATTENUATED FAMILIAL ADENOMATOUS POLYPOSIS

Low match OVARIAN CANCER


Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008).

Related symptoms:

  • Neoplasm
  • Pain
  • Fatigue
  • Respiratory distress
  • Vomiting


SOURCES: OMIM ORPHANET MENDELIAN

More info about OVARIAN CANCER

Low match PUNCTATE PALMOPLANTAR KERATODERMA TYPE 1


Punctate palmoplantar keratoderma type I (PPKP1), also known as Buschke-Fischer-Brauer syndrome, is a very rare hereditary skin disease characterized by irregularly distributed epidermal hyperkeratosis of the palms and soles with wide variation among patients..

PUNCTATE PALMOPLANTAR KERATODERMA TYPE 1 Is also known as palmoplantar keratoderma, punctate type i|ppkp1|keratodermia palmoplantaris papulosa, buschke-fischer-brauer type|buschke-fischer-brauer syndrome|keratosis palmoplantaris papulosa|kppp1

Related symptoms:

  • Neoplasm
  • Pain
  • Dilatation
  • Depressivity
  • Hyperkeratosis


SOURCES: ORPHANET OMIM MENDELIAN

More info about PUNCTATE PALMOPLANTAR KERATODERMA TYPE 1

Low match MUIR-TORRE SYNDROME


Muir-Torre syndrome (MTS) is a form of hereditary nonpolyposis colon cancer (HNPCC) characterized by cutaneous sebaceous tumors, keratoacanthomas and at least one visceral malignancy, most frequently gastrointestinal carcinoma.

MUIR-TORRE SYNDROME Is also known as cutaneous sebaceous neoplasms and keratoacanthomas, multiple, with gastrointestinal and other carcinomas|multiple keratoacanthoma, muir-torre type

Related symptoms:

  • Neoplasm
  • Carcinoma
  • Leukemia
  • Nevus
  • Lymphoma


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about MUIR-TORRE SYNDROME

Low match LI-FRAUMENI SYNDROME


Li-Fraumeni syndrome (LFS) is a rare cancer predisposition syndrome characterized by the early-onset of multiple primary cancers such as breast cancer, soft tissue and bone sarcomas (see these terms), brain tumors and adrenal cortical carcinoma (ACC) (see this term).

LI-FRAUMENI SYNDROME Is also known as sarcoma family syndrome of li and fraumeni|sbla syndrome

Related symptoms:

  • Neoplasm
  • Carcinoma
  • Leukemia
  • Lymphoma
  • Neoplasm of the skin


SOURCES: OMIM ORPHANET MENDELIAN

More info about LI-FRAUMENI SYNDROME

Low match BREAST CANCER


Breast cancer (referring to mammary carcinoma, not mammary sarcoma) is histopathologically and almost certainly etiologically and genetically heterogeneous. Important genetic factors have been indicated by familial occurrence and bilateral involvement.

BREAST CANCER Is also known as breast cancer, familial

Related symptoms:

  • Neoplasm
  • Pain
  • Carcinoma
  • Gynecomastia
  • Breast carcinoma


SOURCES: ORPHANET OMIM MENDELIAN

More info about BREAST CANCER

Top 5 symptoms//phenotypes associated to Lymphoma and Gynecomastia

Symptoms // Phenotype % cases
Carcinoma Very Common - Between 80% and 100% cases
Neoplasm Very Common - Between 80% and 100% cases
Breast carcinoma Very Common - Between 80% and 100% cases
Hodgkin lymphoma Common - Between 50% and 80% cases
Ovarian neoplasm Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Lymphoma and Gynecomastia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Neoplasm of the pancreas Colon cancer Pain Endometrial carcinoma Neoplasm of the skin Dilatation Leukemia Renal cell carcinoma Ovarian carcinoma Intestinal polyp Intestinal polyposis Nevus Prostate cancer Melanoma

Rare Symptoms - Less than 30% cases


Basal cell carcinoma Melanocytic nevus Abnormality of the kidney Squamous cell carcinoma Papule Hemangioma Nausea and vomiting Palmoplantar keratoderma Meningioma Hereditary nonpolyposis colorectal carcinoma Duodenal adenocarcinoma Stomach cancer Hamartoma Neoplasm of the breast Ovarian cyst Macule Diarrhea Sarcoma Colonic diverticula Soft tissue sarcoma Abdominal distention Adenoma sebaceum Abdominal pain Hamartomatous polyposis Transitional cell carcinoma of the bladder Headache Endolymphatic sac tumor Psoriasiform dermatitis Polycystic kidney dysplasia Congenital shortened small intestine Growth abnormality Accelerated skeletal maturation Multiple trichilemmomata Merkel cell skin cancer Hypertension Lobular carcinoma in situ Intestinal obstruction Precocious puberty with Sertoli cell tumor Hyperhidrosis Edema Clubbing Clubbing of fingers Thyroid nodule Nasal polyposis Pancreatic cysts Biliary tract abnormality Abnormality of the mouth Rectal prolapse Vitiligo Abnormality of the ureter Iron deficiency anemia Hypermelanotic macule Uterine neoplasm Intestinal bleeding Hematemesis Thrombophlebitis Bloody diarrhea Testicular neoplasm Intussusception Multiple myeloma Gastrointestinal carcinoma Clear cell renal cell carcinoma Abnormality of metabolism/homeostasis Bladder neoplasm Acute leukemia Neoplasm of the stomach Sebaceous gland carcinoma Keratoacanthoma Laryngeal carcinoma Salivary gland neoplasm Benign gastrointestinal tract tumors Malignant genitourinary tract tumor Benign genitourinary tract neoplasm Nephroblastoma Acute lymphoblastic leukemia Neoplasm of the lung Progressive encephalopathy Osteosarcoma Chondrosarcoma Brain neoplasm Medulloblastoma Rhabdomyosarcoma Adrenocortical carcinoma Lung adenocarcinoma Neoplasm of the nervous system Monoclonal immunoglobulin M proteinemia Plethora Impaired lymphocyte transformation with phytohemagglutinin Neoplasm of the colon Neoplasm of the adrenal cortex Prostate neoplasm Hematological neoplasm Neoplasm of the liver Bladder carcinoma Non-Hodgkin lymphoma Fatigue Respiratory distress Vomiting Conjunctival hamartoma Constipation Weight loss Gastroesophageal reflux Nausea Ascites Increased body weight Back pain Dysgerminoma Ovarian papillary adenocarcinoma Renal neoplasm Depressivity Hyperkeratosis Abnormality of the skin Epidermal acanthosis Thickened skin Abnormality of the nail Scaling skin Parakeratosis Hypergranulosis Orthokeratosis Vasculitis Hyperlipidemia Ductal carcinoma in situ Intellectual disability Dysplastic gangliocytoma of the cerebellum Abnormal cerebellum morphology Immunodeficiency Recurrent infections Pectus excavatum Autism Narrow mouth Hypothyroidism Proximal muscle weakness Intellectual disability, moderate Joint hypermobility Polymicrogyria Hypoplasia of the maxilla Macroglossia Intellectual disability, mild Decreased antibody level in blood Overgrowth Intention tremor Broad thumb Subcutaneous nodule Telangiectasia Chronic diarrhea Exotropia Cafe-au-lait spot Lymphopenia Cranial nerve paralysis Kyphosis Myopathy Increased intracranial pressure Low-set ears Global developmental delay Short stature Generalized hypotonia Hearing impairment Scoliosis Ataxia Hypertelorism Failure to thrive Micrognathia Muscle weakness Cataract Cognitive impairment Atrial septal defect High palate Delayed speech and language development Motor delay Brachydactyly Myopia Skeletal muscle atrophy Macrocephaly Downslanted palpebral fissures Tremor Frontal bossing Hydrocephalus Drooling Hypopigmented skin patches Trichilemmoma Seizures Long penis Cavernous hemangioma Enlarged polycystic ovaries Papilloma Fibroma Generalized hyperkeratosis Neoplasm of the central nervous system Decreased proportion of CD4-positive T cells Subcutaneous lipoma Abnormality of the penis Angioid streaks of the fundus Thyroid adenoma Bone cyst Varicocele Follicular thyroid carcinoma Colorectal polyposis Progressive macrocephaly Pseudopapilledema Mucosal telangiectasiae Acrokeratosis Neoplasm of the thyroid gland Fibroadenoma of the breast Cutis marmorata telangiectatica congenita Enlarged cerebellum Cellular immunodeficiency Astrocytoma Goiter Acute myeloid leukemia Palmoplantar hyperkeratosis Incoordination Dysdiadochokinesis Intracranial hemorrhage Hand polydactyly Cutis marmorata Abnormality of the thyroid gland Multiple lipomas Cystic hygroma Cellulitis Multiple cafe-au-lait spots Hyperthyroidism Abnormality of the uterus Thyroiditis Hashimoto thyroiditis Scaphocephaly Lipoma Abnormality of the vasculature Papilledema Prolactin excess Skin tags Megalencephaly Hydrocele testis Arteriovenous malformation Furrowed tongue Retinoblastoma



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