Lymphoma, and Dementia

Diseases related with Lymphoma and Dementia

In the following list you will find some of the most common rare diseases related to Lymphoma and Dementia that can help you solving undiagnosed cases.

Top matches:

Schimke immuno-osseous dysplasia (SIOD) is a multisystem disorder characterized by spondyloepiphyseal dysplasia and disproportionate short stature, facial dysmorphism, T-cell immunodeficiency, and glomerulonephritis with nephrotic syndrome.

SCHIMKE IMMUNO-OSSEOUS DYSPLASIA Is also known as immunoosseous dysplasia, schimke type|schimke syndrome|spondyloepiphyseal dysplasia-nephrotic syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Scoliosis
  • Growth delay


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about SCHIMKE IMMUNO-OSSEOUS DYSPLASIA

X-linked lymphoproliferative disease is a hereditary immunodeficiency characterized, in the majority of cases, by an inadequate immune response to infection with the Epstein-Barr virus (EBV).

X-LINKED LYMPHOPROLIFERATIVE DISEASE Is also known as xlpd|duncan disease|xlp|immunodeficiency 5|infectious mononucleosis, severe, susceptibility to|purtilo syndrome|imd5|ebvs|lymphoproliferative disease, x-linked|epstein-barr virus infection, familial fatal|lyp|ebv infection, severe, susceptibility to|immun

Related symptoms:

  • Seizures
  • Neoplasm
  • Anemia
  • Hepatomegaly
  • Fever


SOURCES: ORPHANET OMIM MENDELIAN

More info about X-LINKED LYMPHOPROLIFERATIVE DISEASE

Chédiak-Higashi syndrome (CHS) is a rare severe genetic disorder generally characterized by partial oculocutaneous albinism (OCA, see this term), severe immunodeficiency, mild bleeding, neurological dysfunction and lymphoproliferative disorder. A classic, early-onset form and an attenuated, later-onset form (Atypical CHS; see this term) have been described.

CHÉDIAK-HIGASHI SYNDROME Is also known as chÉdiak-higashi-steinbrink syndrome|chÉdiak-higashi disease

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Ataxia


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about CHÉDIAK-HIGASHI SYNDROME

Other less relevant matches:

Nijmegen breakage syndrome is a rare genetic disease presenting at birth with microcephaly, dysmorphic facial features, becoming more noticeable with age, growth delay, and later-onset complications such as malignancies and infections.

NIJMEGEN BREAKAGE SYNDROME Is also known as microcephaly-immunodeficiency-lymphoreticuloma syndrome|ataxia-telangiectasia variant v1|microcephaly with normal intelligence, immunodeficiency, and lymphoreticular malignancies|at-v1|berlin breakage syndrome|ataxia-telangiectasia, variant 1|seemanova sy

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Microcephaly
  • Ataxia


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about NIJMEGEN BREAKAGE SYNDROME

Nasu-Hakola disease (NHD), also referred to as polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), is a rare inherited leukodystrophy characterized by progressive presenile dementia associated with recurrent bone fractures due to polycystic osseous lesions of the lower and upper extremities.

NASU-HAKOLA DISEASE Is also known as plosl|dementia, prefrontal, with bone cysts|plo-sl|dementia, progressive, with lipomembranous polycystic osteodysplasia|nasu-hakola disease|polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy|brain-bone-fat disease|nhd|presenile d

Related symptoms:

  • Seizures
  • Pain
  • Spasticity
  • Gait disturbance
  • Ventriculomegaly


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about NASU-HAKOLA DISEASE

Low match PGM3-CDG

PGM3-CDG is a rare congenital disorder of glycosylation caused by mutations in the PGM3 gene and characterized by neonatal to childhood onset of recurrent bacterial and viral infections, inflammatory skin diseases, atopic dermatitis and atopic diatheses, and marked serum IgE elevation. Early neurologic impairment is evident including developmental delay, intellectual disability, ataxia, dysarthria, sensorineural hearing loss, myoclonus and seizures.

PGM3-CDG Is also known as cid due to pgm3 deficiency|immunodeficiency with hyper ige and cognitive impairment|pgm3-related congenital disorder of glycosylation|combined immunodeficiency due to pgm3 deficiency|immunodeficiency-vasculitis-myoclonus syndrome|ivms

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Generalized hypotonia


SOURCES: OMIM ORPHANET MENDELIAN

More info about PGM3-CDG

A congenital disease caused by an inborn error involving APOLIPOPROTEINS E leading to abnormal LIPID METABOLISM and the accumulation of GLYCOSPHINGOLIPIDS, particularly SPHINGOMYELINS in the HISTIOCYTES. This disorder is characterized by SPLENOMEGALY and the sea-blue histiocytes in the spleen and bone marrow after May Grunwald staining.

SEA-BLUE HISTIOCYTOSIS Is also known as sea-blue histiocytosis|histiocytosis, sea-blue

Related symptoms:

  • Seizures
  • Ataxia
  • Peripheral neuropathy
  • Hepatomegaly
  • Gait disturbance


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about SEA-BLUE HISTIOCYTOSIS

Waldenström macroglobulinemia (WM) is an indolent B-cell lymphoproliferative disorder characterized by the accumulation of monoclonal cells in the bone marrow and peripheral lymphoid tissues, and associated with the production of serum immunoglobulin M (IgM) monoclonal protein.

Related symptoms:

  • Hearing impairment
  • Ataxia
  • Neoplasm
  • Anemia
  • Peripheral neuropathy


SOURCES: OMIM ORPHANET MENDELIAN

More info about WALDENSTRÖM MACROGLOBULINEMIA

Machado-Joseph disease, named for affected families of Azorean extraction, is an autosomal dominant progressive neurologic disorder characterized principally by ataxia, spasticity, and ocular movement abnormalities. Although independently described as a seemingly separate disorder, spinocerebellar ataxia-3 is now known to be the same as Machado-Joseph disease.Three classic clinical subtypes of MJD are recognized: type 1 with early onset and marked pyramidal and dystonic signs; type 2, or pure, with predominant cerebellar ataxia; and type 3 with later-onset and peripheral neuropathy (Franca et al., 2008).

MACHADO-JOSEPH DISEASE; MJD Is also known as spinocerebellar ataxia 3|spinocerebellar atrophy iii|spinopontine atrophy|azorean neurologic disease|nigrospinodentatal degeneration|sca3

Related symptoms:

  • Ataxia
  • Nystagmus
  • Pain
  • Spasticity
  • Ptosis


SOURCES: OMIM MENDELIAN

More info about MACHADO-JOSEPH DISEASE; MJD

Top 5 symptoms//phenotypes associated to Lymphoma and Dementia

Symptoms // Phenotype % cases
Leukemia Common - Between 50% and 80% cases
Ataxia Common - Between 50% and 80% cases
Seizures Common - Between 50% and 80% cases
Thrombocytopenia Uncommon - Between 30% and 50% cases
Immunodeficiency Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Lymphoma and Dementia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Anemia Intellectual disability Fever Recurrent infections Peripheral neuropathy Neoplasm Hepatomegaly Splenomegaly Vasculitis Lymphadenopathy Combined immunodeficiency Abnormality of the eye Hepatosplenomegaly Recurrent respiratory infections Neutropenia Lymphopenia Edema Gliosis Gait disturbance Skeletal muscle atrophy Memory impairment Developmental regression Bronchiectasis Global developmental delay Neurodegeneration B-cell lymphoma Short stature Cerebellar atrophy Diarrhea Pneumonia Myoclonus

Rare Symptoms - Less than 30% cases

Peripheral demyelination Babinski sign Purpura Histiocytosis Pulmonary infiltrates Respiratory insufficiency Abnormality of the nervous system Pancytopenia Falls Proptosis Spinocerebellar tract degeneration Hemolytic anemia Spasticity Respiratory failure Pain Cafe-au-lait spot Polyneuropathy Mucopolysacchariduria Cellular immunodeficiency Lymphoproliferative disorder Dysgammaglobulinemia Gingival bleeding Generalized hypotonia Rigidity Gastrointestinal hemorrhage Parkinsonism Abnormal bleeding Hypopigmentation of the skin Abnormality of extrapyramidal motor function Sensory neuropathy Epistaxis Cutaneous photosensitivity Mental deterioration Hypertriglyceridemia Bradykinesia Hyporeflexia Hyperpigmentation of the skin Dysarthria Leukopenia Cranial nerve paralysis Tremor Hearing impairment Visual impairment Nystagmus Abnormality of movement Acute leukemia Stroke Short neck Cognitive impairment Depressed nasal bridge Glomerulonephritis Encephalitis Reduced bone mineral density Bone marrow hypocellularity Intrauterine growth retardation Migraine Growth delay Brain atrophy Abnormal cerebellum morphology Congestive heart failure Renal insufficiency Headache Malabsorption Autoimmunity Abnormal facial shape Abnormality of epiphysis morphology Melanocytic nevus Scoliosis Mastoiditis Functional abnormality of the gastrointestinal tract Failure to thrive Supranuclear ophthalmoplegia Euphoria Lack of insight Abnormal adipose tissue morphology Caudate atrophy Frontal lobe dementia Downbeat nystagmus Abnormal hair quantity Agnosia Abnormal upper motor neuron morphology Inappropriate behavior Primitive reflex Bone cyst Decrease in T cell count Disinhibition Sensorineural hearing impairment Glioma Rhabdomyosarcoma Hypometric saccades Abnormal eyelid morphology Myokymia Low back pain Dilated fourth ventricle Recurrent bronchitis Chronic pain Torsion dystonia Restless legs Senile plaques Recurrent sinopulmonary infections Brachydactyly Medulloblastoma Dysmetric saccades High palate Delirium Abnormality of chromosome stability Cerebral edema Axonal loss Neurofibrillary tangles Facial-lingual fasciculations Aggressive behavior Recurrent infection of the gastrointestinal tract EEG abnormality Palatal myoclonus Arthralgia Skeletal dysplasia Cerebral cortical atrophy Anorectal anomaly Neurological speech impairment Cerebral atrophy Penoscrotal hypospadias Behavioral abnormality Hydrocephalus Hypoplasia of the corpus callosum Ventriculomegaly Malar prominence Irritability T-cell lymphoma Progressive vitiligo Bone pain Basal ganglia calcification Pathologic fracture Alzheimer disease Personality changes Abnormality of the hand Leukoencephalopathy Oculomotor apraxia B lymphocytopenia Abnormality of the foot Olivopontocerebellar atrophy Apraxia Pollakisuria Cerebral calcification Urinary incontinence Limitation of joint mobility Impaired horizontal smooth pursuit Chorea Ophthalmoplegia Spastic dysarthria Tongue fasciculations Postural instability Hypercoagulability Edema of the lower limbs Raynaud phenomenon Elevated erythrocyte sedimentation rate Cutis marmorata Pleural effusion Urticaria Anorexia Muscle cramps Reduced consciousness/confusion Vertigo Progressive cerebellar ataxia Neuronal loss in central nervous system Limb ataxia Pallor Diplopia Hallucinations Fasciculations Weight loss Abnormality of the retinal vasculature Periorbital edema Fatigue Ptosis Abnormal pyramidal sign Anxiety Gait ataxia Diabetes mellitus Depressivity Dystonia Dysphagia Optic atrophy Flexion contracture Unsteady gait Distal amyotrophy Confusion Polyclonal elevation of IgM Cryoglobulinemia Impaired lymphocyte transformation with phytohemagglutinin Monoclonal immunoglobulin M proteinemia Multifocal epileptiform discharges Retinal hemorrhage Abnormality of neutrophils Normocytic anemia Visual loss Sea-blue histiocytosis Abnormality of the skeletal system Eczema Amyotrophic lateral sclerosis Gaze-evoked nystagmus Decreased number of peripheral myelinated nerve fibers Recurrent skin infections Narrow palpebral fissure Atrophy/Degeneration affecting the brainstem Progressive external ophthalmoplegia Inflammatory abnormality of the skin Sensory impairment Impaired vibratory sensation Asthma Urinary bladder sphincter dysfunction Delusions Absent Achilles reflex Erythema Abnormality of eye movement Respiratory tract infection Conductive hearing impairment Gastroesophageal reflux Atopic dermatitis Akinesia Elevated serum acid phosphatase Subcutaneous nodule Absent axillary hair Hearing abnormality Chronic myelogenous leukemia Truncal ataxia Blepharitis Autoimmune thrombocytopenia Abnormal autonomic nervous system physiology Petechiae External ophthalmoplegia Cirrhosis Ophthalmoparesis Back pain Retinopathy Cortical myoclonus Autoimmune neutropenia Vasculitis in the skin Membranoproliferative glomerulonephritis Allergic rhinitis Severe combined immunodeficiency Spinal muscular atrophy Mediastinal lymphadenopathy Generalized hypopigmentation of hair Acute lymphoblastic leukemia Cerebral ischemia Steroid-resistant nephrotic syndrome Multiple lentigines Hypoplasia of the capital femoral epiphysis Arteriosclerosis Right ventricular cardiomyopathy Dentinogenesis imperfecta Subvalvular aortic stenosis Precocious atherosclerosis Villous atrophy Increased thyroid-stimulating hormone level Disproportionate short-trunk short stature Ovoid vertebral bodies Thoracic kyphosis Transient ischemic attack Abnormality of the vasculature Protuberant abdomen Glomerulopathy Multiple cafe-au-lait spots Steatorrhea Shallow acetabular fossae Encephalomalacia High pitched voice Meningitis Lymphocytosis Recurrent pharyngitis Immune dysregulation Aplastic anemia Agammaglobulinemia IgG deficiency Hodgkin lymphoma Increased antibody level in blood Sarcoma Hemiparesis Abnormal T cell morphology Decreased antibody level in blood Hepatic failure Dilatation Lateral displacement of the femoral head Nephrosclerosis Anterior pituitary dysgenesis Premature arteriosclerosis Moyamoya phenomenon Abnormal immunoglobulin level Hypermelanotic macule Emphysema Granulomatosis Proteinuria Stage 5 chronic kidney disease Astigmatism Platyspondyly Hip dislocation Corneal opacity Scarring Hyperlordosis Abnormality of the kidney Thin upper lip vermilion Bulbous nose Osteopenia Hypothyroidism Kyphosis Abnormality of the dentition Vomiting Cardiomyopathy Myopia Hypertension Motor delay Abnormality of skin pigmentation Nephropathy Focal segmental glomerulosclerosis Opacification of the corneal stroma Spondyloepiphyseal dysplasia Nephritis Epiphyseal dysplasia Glomerulosclerosis Chronic kidney disease Coarse hair Azoospermia Hyperlipidemia Atherosclerosis Heterotopia Premature birth Abnormal form of the vertebral bodies Abnormal lung morphology Fine hair Intellectual disability, profound Lumbar hyperlordosis Nephrotic syndrome Microdontia Decreased testicular size Waddling gait Hepatic encephalopathy Chorioretinitis Anal stenosis Retrognathia Prominent nose Cleft upper lip Anal atresia Small for gestational age Prominent nasal bridge Attention deficit hyperactivity disorder Intellectual disability, moderate Hydronephrosis Macrotia Convex nasal ridge Hyperactivity Upslanted palpebral fissure Hypospadias Cleft palate Muscle weakness Micrognathia Microcephaly Recurrent systemic pyogenic infections Abnormality of multiple cell lineages in the bone marrow Otitis media Amenorrhea Recurrent cutaneous abscess formation Cachexia Neuroblastoma Autoimmune hemolytic anemia Abnormality of the musculature Freckling Long nose Non-midline cleft lip Abnormality of neuronal migration Premature ovarian insufficiency Deep philtrum Recurrent pneumonia Sloping forehead Low anterior hairline Abnormality of the hair Sinusitis Telangiectasia Chronic diarrhea Recurrent urinary tract infections Abnormality of the face Choanal atresia Primary amenorrhea Giant melanosomes in melanocytes Abnormal leukocyte morphology Increased IgM level Reduced visual acuity Bruising susceptibility Peripheral axonal neuropathy Paresthesia Paraplegia Spastic paraplegia Photophobia Difficulty walking Jaundice Areflexia Skin ulcer Atrial septal defect Strabismus Fulminant hepatitis Reduced natural killer cell activity Pharyngitis Non-Hodgkin lymphoma Burkitt lymphoma Hepatic necrosis Pure red cell aplasia Amblyopia Foot dorsiflexor weakness Hypofibrinogenemia Fair hair Oculogyric crisis Recurrent bacterial skin infections Macular hypoplasia Partial albinism Hypersplenism Progressive peripheral neuropathy Hemophagocytosis White hair Generalized hypopigmentation Periodontitis Abnormality of vision Gingivitis Iris hypopigmentation Hypopigmentation of hair Generalized hyperpigmentation Resting tremor Sensory axonal neuropathy Cerebral hemorrhage Albinism Decreased nerve conduction velocity Abnormal electrooculogram


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