Leukemia, and Amyotrophic lateral sclerosis

Diseases related with Leukemia and Amyotrophic lateral sclerosis

In the following list you will find some of the most common rare diseases related to Leukemia and Amyotrophic lateral sclerosis that can help you solving undiagnosed cases.

Top matches:

Machado-Joseph disease, named for affected families of Azorean extraction, is an autosomal dominant progressive neurologic disorder characterized principally by ataxia, spasticity, and ocular movement abnormalities. Although independently described as a seemingly separate disorder, spinocerebellar ataxia-3 is now known to be the same as Machado-Joseph disease.Three classic clinical subtypes of MJD are recognized: type 1 with early onset and marked pyramidal and dystonic signs; type 2, or pure, with predominant cerebellar ataxia; and type 3 with later-onset and peripheral neuropathy (Franca et al., 2008).

MACHADO-JOSEPH DISEASE; MJD Is also known as spinocerebellar ataxia 3|spinocerebellar atrophy iii|spinopontine atrophy|azorean neurologic disease|nigrospinodentatal degeneration|sca3

Related symptoms:

  • Ataxia
  • Nystagmus
  • Pain
  • Spasticity
  • Ptosis


SOURCES: OMIM MENDELIAN

More info about MACHADO-JOSEPH DISEASE; MJD

Related symptoms:

  • Dementia
  • Pallor
  • Neuronal loss in central nervous system
  • Amyotrophic lateral sclerosis


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 23; ALS23

Other less relevant matches:

Related symptoms:

  • Dementia
  • Mental deterioration
  • Amyotrophic lateral sclerosis
  • Frontotemporal dementia
  • Abnormal lower motor neuron morphology


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 22 WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA; ALS22

Related symptoms:

  • Muscular dystrophy
  • Elevated alkaline phosphatase
  • Amyotrophic lateral sclerosis
  • Rimmed vacuoles
  • Muscle fiber inclusion bodies


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 20; ALS20

Related symptoms:

  • Skeletal muscle atrophy
  • Amyotrophic lateral sclerosis
  • Bulbar signs
  • Upper motor neuron dysfunction


SOURCES: OMIM MESH MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 11; ALS11

Amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam is a neurodegenerative disorder with unusually high incidence among the Chamorro people of Guam. Both ALS and parkinsonism-dementia are chronic, progressive, and uniformly fatal disorders in this population. Both diseases are known to occur in the same kindred, the same sibship, and even the same individual.

AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM-DEMENTIA COMPLEX Is also known as guam disease|als-pdc|parkinsonism-dementia-als complex|pdals|amyotrophic lateral sclerosis-parkinsonism-dementia of guam syndrome|amyotrophic lateral sclerosis-parkinsonism/dementia complex of guam|lytico-bodig disease

Related symptoms:

  • Muscle weakness
  • Dementia
  • Paralysis
  • Muscle cramps
  • Parkinsonism


SOURCES: OMIM ORPHANET MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM-DEMENTIA COMPLEX

Related symptoms:

  • Muscle weakness
  • Spasticity
  • Hyperreflexia
  • Paralysis
  • Lower limb spasticity


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 16, JUVENILE; ALS16

Related symptoms:

  • Spasticity
  • Dementia
  • Distal muscle weakness
  • Distal amyotrophy
  • Parkinsonism


SOURCES: OMIM MESH MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 9; ALS9

Related symptoms:

  • Cognitive impairment
  • Respiratory insufficiency due to muscle weakness
  • Amyotrophic lateral sclerosis
  • Loss of ability to walk


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 19; ALS19

Top 5 symptoms//phenotypes associated to Leukemia and Amyotrophic lateral sclerosis

Symptoms // Phenotype % cases
Dementia Uncommon - Between 30% and 50% cases
Abnormal lower motor neuron morphology Uncommon - Between 30% and 50% cases
Spasticity Uncommon - Between 30% and 50% cases
Parkinsonism Uncommon - Between 30% and 50% cases
Paralysis Rare - less than 30% cases

Other less frequent symptoms

Patients with Leukemia and Amyotrophic lateral sclerosis. may also develop some of the following symptoms:

Rare Symptoms - Less than 30% cases

Frontotemporal dementia Distal amyotrophy Muscle weakness Skeletal muscle atrophy Bulbar palsy Neuronal loss in central nervous system Muscle cramps Chronic pain Dilated fourth ventricle Low back pain Torsion dystonia Hypometric saccades Ataxia Tongue fasciculations Myokymia Olivopontocerebellar atrophy Spastic dysarthria Spinocerebellar tract degeneration Absent Achilles reflex Delusions Urinary bladder sphincter dysfunction Progressive external ophthalmoplegia Atrophy/Degeneration affecting the brainstem Decreased number of peripheral myelinated nerve fibers Restless legs Impaired horizontal smooth pursuit Dysmetric saccades Muscle fiber inclusion bodies Respiratory insufficiency due to muscle weakness Cognitive impairment Distal muscle weakness Abnormal upper motor neuron morphology Lower limb spasticity Hyperreflexia Upper motor neuron dysfunction Bulbar signs Rimmed vacuoles Delirium Elevated alkaline phosphatase Muscular dystrophy Mental deterioration Pallor Abnormal electrooculogram Facial-lingual fasciculations Palatal myoclonus Downbeat nystagmus Supranuclear ophthalmoplegia Gaze-evoked nystagmus Back pain Impaired vibratory sensation Dystonia Abnormality of the eye Anxiety Rigidity Proptosis Gait ataxia Diabetes mellitus Myoclonus Babinski sign Depressivity Cerebellar atrophy Dysphagia Tremor Optic atrophy Dysarthria Peripheral neuropathy Visual impairment Flexion contracture Ptosis Pain Abnormal pyramidal sign Ophthalmoplegia Akinesia Limb ataxia Ophthalmoparesis Spinal muscular atrophy Nystagmus External ophthalmoplegia Abnormal autonomic nervous system physiology Truncal ataxia Fasciculations Hallucinations Diplopia Abnormality of extrapyramidal motor function Abnormality of eye movement Bradykinesia Gliosis Progressive cerebellar ataxia Abnormal cerebellum morphology Postural instability Polyneuropathy Neurodegeneration Sensory neuropathy Confusion Unsteady gait Loss of ability to walk


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