Hypertension, and Vertigo

Diseases related with Hypertension and Vertigo

In the following list you will find some of the most common rare diseases related to Hypertension and Vertigo that can help you solving undiagnosed cases.

Top matches:

Related symptoms:

  • Neoplasm
  • Hypertension
  • Hyperhidrosis
  • Vertigo
  • Tachycardia


SOURCES: OMIM MENDELIAN

More info about PARAGANGLIOMAS 5; PGL5

Orthostatic hypotension-2 is an autosomal recessive disorder characterized by severe orthostatic hypotension, recurrent hypoglycemia, and low norepinephrine levels. The disorder has onset in infancy or early childhood. Some patients may also have renal dysfunction and reduced life expectancy. The disorder results from a defect in the biosynthesis of norepinephrine from dopamine due to a cofactor deficiency.For a discussion of genetic heterogeneity of ORTHYP, see ORTHYP1 (OMIM ).

Related symptoms:

  • Anemia
  • Hypoglycemia
  • Vertigo
  • Tachycardia
  • Hypotension


SOURCES: OMIM MENDELIAN

More info about ORTHOSTATIC HYPOTENSION 2; ORTHYP2

Atrial fibrillation (AF) is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, and to 5.9% over the age of 65. The most dreaded complication is thromboembolic stroke (Brugada et al., 1997).For a discussion of genetic heterogeneity of atrial fibrillation, see {608583}.

Related symptoms:

  • Hypertension
  • Cardiomyopathy
  • Stroke
  • Vertigo
  • Tachycardia


SOURCES: OMIM MESH MENDELIAN

More info about ATRIAL FIBRILLATION, FAMILIAL, 6; ATFB6

Other less relevant matches:

Primary familial polycythemia is an inherited hematological disorder resulting from mutations in the erythropoietin (EPO) receptor and is characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production in the presence of low EPO levels.

PRIMARY FAMILIAL POLYCYTHEMIA Is also known as polycythemia, primary familial and congenital|primary familial and congenital polycythemia|familial erythrocytosis|erythrocytosis, autosomal dominant benign|pfcp|congenital polycythemia due to erythropoietin receptor mutation|congenital erythrocytosis due

Related symptoms:

  • Pain
  • Hypertension
  • Fatigue
  • Respiratory distress
  • Splenomegaly


SOURCES: OMIM ORPHANET MENDELIAN

More info about PRIMARY FAMILIAL POLYCYTHEMIA

Dopamine beta-hydroxylase deficiency is an extremely rare genetic metabolic disorder characterized by autonomic dysregulation leading mainly to orthostatic hypotension.

DOPAMINE BETA-HYDROXYLASE DEFICIENCY Is also known as norepinephrine deficiency|noradrenaline deficiency

Related symptoms:

  • Seizures
  • Generalized hypotonia
  • Muscular hypotonia
  • Pain
  • Ptosis


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about DOPAMINE BETA-HYDROXYLASE DEFICIENCY

Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN, see this term) characterized by a sustained elevation of platelet number (> 450 x 109/L) with a tendency for thrombosis and hemorrhage.

ESSENTIAL THROMBOCYTHEMIA Is also known as thrombocytosis 1|essential thrombocytosis|et

Related symptoms:

  • Pain
  • Hypertension
  • Hepatomegaly
  • Abnormality of the skeletal system
  • Respiratory distress


SOURCES: ORPHANET OMIM MENDELIAN

More info about ESSENTIAL THROMBOCYTHEMIA

Primary pulmonary arterial hypertension is a rare, often fatal, progressive vascular lung disease characterized by increased pulmonary vascular resistance and sustained elevation of mean pulmonary arterial pressure, leading to right ventricular hypertrophy and right heart failure. Pathologic features include a narrowing and thickening of small pulmonary vessels and plexiform lesions. There is pulmonary vascular remodeling of all layers of pulmonary arterial vessels: intimal thickening, smooth muscle cell hypertrophy or hyperplasia, adventitial fibrosis, and occluded vessels by in situ thrombosis (summary by Machado et al., 2009 and Han et al., 2013).Heterozygous mutations in the BMPR2 gene are found in nearly 70% of families with heritable PPH and in 25% of patients with sporadic disease. The disease is more common in women (female:male ratio of 1.7:1). However, the penetrance of PPH1 is incomplete: only about 10 to 20% of individuals with BMPR2 mutations develop the disease during their lifetime, suggesting that development of the disorder is triggered by other genetic or environmental factors. Patients with PPH1 are less likely to respond to acute vasodilater testing and are unlikely to benefit from treatment with calcium channel blockade (summary by Machado et al., 2009 and Han et al., 2013). Genetic Heterogeneity of Primary Pulmonary HypertensionPPH2 (OMIM ) is caused by mutation in the SMAD9 gene (OMIM ) on chromosome 13q13; PPH3 (OMIM ) is caused by mutation in the CAV1 gene (OMIM ) on chromosome 7q31; and PPH4 (OMIM ) is caused by mutation in the KCNK3 gene (OMIM ) on chromosome 2p23.See {265400} for a possible autosomal recessive form of PPH.Primary pulmonary hypertension may also be found in association with hereditary hemorrhagic telangiectasia type 1 (HHT1 ), caused by mutation in the ENG gene (OMIM ), and HHT2 (OMIM ), caused by mutation in the ACVRL1 (ALK1) gene (OMIM ).

PULMONARY HYPERTENSION, PRIMARY, 1; PPH1 Is also known as pulmonary arterial hypertension|pht|pah

Related symptoms:

  • Pain
  • Hypertension
  • Hepatomegaly
  • Fatigue
  • Respiratory distress


SOURCES: OMIM ORPHANET MENDELIAN

More info about PULMONARY HYPERTENSION, PRIMARY, 1; PPH1

Medium match POLYCYTHEMIA VERA

Polycythemia vera (PV) is an acquired myeloproliferative disorder characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production, frequently associated with uncontrolled white blood cell and platelet production.

POLYCYTHEMIA VERA Is also known as polycythemia rubra vera|acquired primary erythrocytosis|prv|vaquez disease|osler-vaquez disease|pv

Related symptoms:

  • Neoplasm
  • Visual impairment
  • Hypertension
  • Hepatomegaly
  • Fatigue


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about POLYCYTHEMIA VERA

Medium match SNEDDON SYNDROME

Sneddon's syndrome (SS) is a rare non-inflammatory thrombotic vasculopathy characterized by the combination of cerebrovascular disease with livedo racemosa.

SNEDDON SYNDROME Is also known as livedo reticularis-cerebrovascular accident syndrome|livedo racemosa-cerebrovascular accident syndrome|livedo reticularis and cerebrovascular accidents|ehrmann-sneddon syndrome

Related symptoms:

  • Seizures
  • Muscle weakness
  • Pain
  • Visual impairment
  • Motor delay


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about SNEDDON SYNDROME

Juvenile polyposis syndrome is an autosomal dominant condition that predisposes gene carriers to various types of tumors. The diagnosis is based on the occurrence of hamartomatous gastrointestinal polyps that turn into malignant lesions in approximately 20% of cases (Handra-Luca et al., 2005).It had been suggested that juvenile polyposis can be caused by mutations in the PTEN gene (OMIM ), the same gene that is mutant in Cowden syndrome-1 (OMIM ). In a comprehensive review of PTEN, Waite and Eng (2002) concluded that juvenile intestinal polyposis is not a so-called PTEN hamartoma-tumor syndrome (PHTS). They suggested that the discovery of the germline PTEN mutation in an individual considered to have JPS should raise a suspicion that the clinical diagnosis is incorrect and that such an individual should be managed medically in the same manner as all patients with PHTS.

JUVENILE POLYPOSIS SYNDROME; JPS Is also known as polyposis, juvenile intestinal|pji|jip|juvenile intestinal polyposis|polyposis, familial, of entire gastrointestinal tract

Related symptoms:

  • Seizures
  • Neoplasm
  • Failure to thrive
  • Pain
  • Cryptorchidism


SOURCES: OMIM MENDELIAN

More info about JUVENILE POLYPOSIS SYNDROME; JPS

Top 5 symptoms//phenotypes associated to Hypertension and Vertigo

Symptoms // Phenotype % cases
Pain Common - Between 50% and 80% cases
Headache Uncommon - Between 30% and 50% cases
Stroke Uncommon - Between 30% and 50% cases
Respiratory distress Uncommon - Between 30% and 50% cases
Dyspnea Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Hypertension and Vertigo. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Fatigue Epistaxis Myocardial infarction Hepatomegaly Cough Myalgia Venous thrombosis Abdominal pain Polycythemia Splenomegaly Leukemia Neoplasm Seizures Acrocyanosis Chest pain Tachycardia Thrombocytosis Hypotension

Rare Symptoms - Less than 30% cases

Abnormal thrombosis Hemoptysis Telangiectasia Myelofibrosis Cyanosis Arterial thrombosis Bruising susceptibility Acute leukemia Amaurosis fugax Transient ischemic attack Pulmonary embolism Congestive heart failure Leukocytosis Myelodysplasia Increased megakaryocyte count Gastrointestinal hemorrhage Myeloproliferative disorder Increased red blood cell mass Cerebral hemorrhage Portal hypertension Visual impairment Anemia Hypoglycemia Orthostatic hypotension Recurrent hypoglycemia Palpitations Thromboembolic stroke Cerebral ischemia Arthralgia Pruritus Increased hematocrit Thromboembolism Increased hemoglobin Mental deterioration Deep venous thrombosis Intracranial hemorrhage Muscle weakness Hemiplegia Gingival bleeding Systemic lupus erythematosus Motor delay Dysarthria Tremor Vasculitis Hemiparesis Behavioral abnormality Angina pectoris Developmental regression Portal vein thrombosis Dementia Memory impairment Facial palsy Migraine Budd-Chiari syndrome Intermittent claudication Chorea Nephropathy Confusion Erythroid hyperplasia Paralysis Elevated leukocyte alkaline phosphatase Arterial stenosis Personality changes Rectal prolapse Hypoalbuminemia Clubbing Colon cancer Hamartoma Hematochezia Clubbing of fingers Intestinal polyposis Stomach cancer Diplopia Hamartomatous polyposis Hematemesis Melena Intussusception Multiple gastric polyps Duodenal adenocarcinoma Adenocarcinoma of the colon Hypokalemia Carcinoma Heart murmur Hemianopia Cutis marmorata Aphasia Visual field defect Atrophic scars Arteriovenous malformation Peripheral arterial stenosis Facial paralysis Vascular skin abnormality Jaundice Antiphospholipid antibody positivity Lupus anticoagulant Failure to thrive Cryptorchidism Macrocephaly Diarrhea Hernia Umbilical hernia Tinnitus Cardiomegaly Erythema Hypothermia Dehydration Abnormal autonomic nervous system physiology Epiphora Blurred vision Amyloidosis Neonatal hypoglycemia Multiple myeloma Abnormality of the nervous system Nocturia Intermittent hypothermia Retrograde ejaculation Abnormality of the skeletal system Hepatosplenomegaly Paresthesia Syncope Vomiting Prolonged bleeding time Abnormal bleeding Hyperhidrosis Pheochromocytoma Paraganglioma Cardiomyopathy Atrial fibrillation Sick sinus syndrome Exertional dyspnea Peripheral neuropathy Abnormal hemoglobin Plethora Peripheral thrombosis Generalized hypotonia Muscular hypotonia Ptosis High palate Lymphoma Myeloid leukemia Weight loss Hemangiomatosis Right ventricular hypertrophy Edema of the lower limbs Right ventricular failure Abnormal tricuspid valve morphology Spontaneous, recurrent epistaxis Increased pulmonary vascular resistance Pulmonary capillary hemangiomatosis Scleroderma Elevated right atrial pressure Arterial intimal fibrosis Pulmonary arterial medial hypertrophy Pulmonary aterial intimal fibrosis Pulmonary artery vasoconstriction Respiratory insufficiency Thrombocytopenia Capillary hemangioma Hoarse voice Gangrene Decreased mean platelet volume Abnormality of the cerebral vasculature Abnormal thrombocyte morphology Impaired platelet aggregation Abnormality of bone marrow cell morphology Bloody diarrhea Abnormal platelet morphology Abnormal platelet aggregation Abnormal lung morphology Edema Recurrent respiratory infections Cirrhosis Ascites Sudden cardiac death Pulmonary arterial hypertension Ventricular hypertrophy Hepatic vascular malformations


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