Hypertension, and Sparse scalp hair

Diseases related with Hypertension and Sparse scalp hair

In the following list you will find some of the most common rare diseases related to Hypertension and Sparse scalp hair that can help you solving undiagnosed cases.

Top matches:

Hypotrichosis - lymphedema - telangiectasia is an extremely rare syndromic lymphedema disorder characterized by early-onset hypotrichosis, childhood-onset lymphedema, and variable telangiectasia, particularly of the palms.

HYPOTRICHOSIS-LYMPHEDEMA-TELANGIECTASIA-RENAL DEFECT SYNDROME Is also known as hypotrichosis-lymphedema-telangiectasia-membranoproliferative glomerulonephritis syndrome

Related symptoms:

  • Hypertension
  • Respiratory distress
  • Abnormality of the dentition
  • Alopecia
  • Hyperhidrosis


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about HYPOTRICHOSIS-LYMPHEDEMA-TELANGIECTASIA-RENAL DEFECT SYNDROME

LMNA-related cardiocutaneous progeria syndrome is a rare, genetic, premature aging syndrome characterized by adulthood-onset cutaneous manifestations that result in a prematurely aged appearance (i.e. premature thinning and graying of scalp hair, loss of subcutaneous fat, tightening of skin) associated with prominent cardiovascular manifestations, such as accelerated atherosclerosis, calcific valve disease, and cardiomyopathy. Patients present loss of eyebrows and eyelashes in childhood and have a predisposition to develop malignancies.

LMNA-RELATED CARDIOCUTANEOUS PROGERIA SYNDROME Is also known as lcps

Related symptoms:

  • Hypertension
  • Cardiomyopathy
  • Congestive heart failure
  • Sparse hair
  • Ventricular hypertrophy


SOURCES: ORPHANET MENDELIAN

More info about LMNA-RELATED CARDIOCUTANEOUS PROGERIA SYNDROME

Some ectodermal dysplasias are here classified as congenital disorders characterized by abnormal development in 2 or more ectodermal structures (hair, nails, teeth, and sweat glands) without other systemic findings.Hypohidrotic, or anhidrotic, ectodermal dysplasia (HED/EDA) is characterized by a triad of signs comprising sparse hair (hypotrichosis), abnormal or missing teeth (anodontia or hypodontia), and inability to sweat (anhidrosis or hypohidrosis). Typical clinical manifestations also include dryness of the skin, eyes, airways, and mucous membranes presumably due to the defective development of several exocrine glands. Hypohidrotic ectodermal dysplasia can be associated with dysmorphic features (forehead bumps, rings under the eyes, everted nose, and prominent lips) and occasionally with absent nipples. Ectodermal dysplasia-1, due to mutation in the EDA gene, is the most frequent form of hypohidrotic ectodermal dysplasia (summary by Cluzeau et al., 2011).

X-LINKED HYPOHIDROTIC ECTODERMAL DYSPLASIA Is also known as xhed|ectd1|cst syndrome|ed1|christ-siemens-touraine syndrome|eda1|eda|ectodermal dysplasia, anhidrotic, x-linked|ectodermal dysplasia, hypohidrotic, 1|x-linked anhidrotic ectodermal dysplasia|hed1|xlhed|ectodermal dysplasia 1, hypohidrotic/hair/tooth type

Related symptoms:

  • Intellectual disability
  • Feeding difficulties
  • Depressed nasal bridge
  • Hypertension
  • Fever


SOURCES: OMIM ORPHANET MENDELIAN

More info about X-LINKED HYPOHIDROTIC ECTODERMAL DYSPLASIA

Other less relevant matches:

Classical homocystinuria due to cystathionine beta-synthase (CbS) deficiency is characterized by the multiple involvement of the eye, skeleton, central nervous system, and vascular system.

CLASSIC HOMOCYSTINURIA Is also known as cystathionine beta-synthase deficiency|homocystinuria due to cystathionine beta-synthase deficiency

Related symptoms:

  • Intellectual disability
  • Seizures
  • Scoliosis
  • Cataract
  • High palate


SOURCES: ORPHANET MENDELIAN

More info about CLASSIC HOMOCYSTINURIA

Related symptoms:

  • Global developmental delay
  • Hearing impairment
  • Microcephaly
  • Growth delay
  • Failure to thrive


SOURCES: ORPHANET OMIM MENDELIAN

More info about NEUTROPENIA, SEVERE CONGENITAL, 4, AUTOSOMAL RECESSIVE; SCN4

Johanson-Blizzard syndrome (JBS) is a multiple congenital anomaly characterized by exocrine pancreatic insufficiency, hypoplasia/aplasia of the nasal alae, hypodontia, sensorineural hearing loss, growth retardation, anal and urogenital malformations, and variable intellectual disability.

JOHANSON-BLIZZARD SYNDROME Is also known as jbs|nasal alar hypoplasia, hypothyroidism, pancreatic achylia, and congenital deafness

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Generalized hypotonia
  • Hearing impairment


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about JOHANSON-BLIZZARD SYNDROME

Medium match WERNER SYNDROME

Werner syndrome (WS) is a rare inherited syndrome characterized by premature aging with onset in the third decade of life and with cardinal clinical features including bilateral cataracts, short stature, graying and thinning of scalp hair, characteristic skin disorders and premature onset of additional age-related disorders.

WERNER SYNDROME Is also known as ws|adult progeria

Related symptoms:

  • Short stature
  • Neoplasm
  • Pain
  • Cataract
  • Visual impairment


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about WERNER SYNDROME

Mandibuloacral dysplasia with type A lipodystrophy (MADA) is an autosomal recessive disorder characterized by growth retardation, craniofacial anomalies with mandibular hypoplasia, skeletal abnormalities with progressive osteolysis of the distal phalanges and clavicles, and pigmentary skin changes. The lipodystrophy is characterized by a marked acral loss of fatty tissue with normal or increased fatty tissue in the neck and trunk. Some patients may show progeroid features. Metabolic complications can arise due to insulin resistance and diabetes (Young et al., 1971; Simha and Garg, 2002; summary by Garavelli et al., 2009).See also MAD type B (MADB ), which is caused by mutation in the ZMPSTE24 gene (OMIM ).

MANDIBULOACRAL DYSPLASIA WITH TYPE A LIPODYSTROPHY; MADA Is also known as craniomandibular dermatodysostosis|lipodystrophy, type a, associated with mandibuloacral dysplasia

Related symptoms:

  • Short stature
  • Generalized hypotonia
  • Hearing impairment
  • Growth delay
  • Neoplasm


SOURCES: OMIM MENDELIAN

More info about MANDIBULOACRAL DYSPLASIA WITH TYPE A LIPODYSTROPHY; MADA

Gorlin-Chaudhry-Moss (GCM) syndrome is a multiple congenital anomaly syndrome characterized by craniofacial dysostosis, facial dysmorphism, conductive hearing loss, generalized hypertrichosis, and extremity, ocular and dental anomalies.

GORLIN-CHAUDHRY-MOSS SYNDROME Is also known as gcm syndrome|gorlin-chaudhry-moss syndrome|craniofacial dysostosis, hypertrichosis, hypoplasia of labia majora, dental and eye anomalies, patent ductus arteriosus, and normal intelligence|craniofacial dysostosis-genital, dental, cardiac anomalies syndrome

Related symptoms:

  • Global developmental delay
  • Short stature
  • Generalized hypotonia
  • Hearing impairment
  • Microcephaly


SOURCES: OMIM ORPHANET MENDELIAN

More info about GORLIN-CHAUDHRY-MOSS SYNDROME

Medium match YUNIS-VARON SYNDROME

Yunis-Varon syndrome is a severe autosomal recessive disorder characterized by skeletal defects, including cleidocranial dysplasia and digital anomalies, and severe neurologic involvement with neuronal loss. Enlarged cytoplasmic vacuoles are found in neurons, muscle, and cartilage. The disorder is usually lethal in infancy (summary by Campeau et al., 2013).

YUNIS-VARON SYNDROME Is also known as cleidocranial dysplasia with micrognathia, absent thumbs, and distal aphalangia|cleidocranial dysplasia-micrognathia-absent thumbs syndrome

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Generalized hypotonia
  • Hearing impairment


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about YUNIS-VARON SYNDROME

Top 5 symptoms//phenotypes associated to Hypertension and Sparse scalp hair

Symptoms // Phenotype % cases
Abnormality of the dentition Common - Between 50% and 80% cases
Sparse hair Common - Between 50% and 80% cases
Short stature Uncommon - Between 30% and 50% cases
Respiratory distress Uncommon - Between 30% and 50% cases
Hypotrichosis Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Hypertension and Sparse scalp hair. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Hearing impairment Growth delay Absent eyebrow Postnatal growth retardation Micropenis Intellectual disability Short nose Generalized hypotonia Failure to thrive Atrial septal defect Cryptorchidism Convex nasal ridge Microcephaly Global developmental delay Hepatomegaly High palate Prematurely aged appearance Cataract Proptosis Alopecia Intrauterine growth retardation Hypoplasia of the maxilla Absent eyelashes Diabetes mellitus Abnormal heart morphology Hypospadias Feeding difficulties Depressed nasal bridge Single transverse palmar crease Edema Microdontia Sepsis Dermal atrophy Pulmonary arterial hypertension Prominent superficial veins Short distal phalanx of finger Premature loss of teeth Hypoplastic nipples Muscle weakness Thin skin Atherosclerosis Narrow mouth Micrognathia Aplasia/Hypoplasia of the eyebrow Cardiomyopathy Hernia Osteoporosis Absent nipple Joint stiffness Reduced subcutaneous adipose tissue

Rare Symptoms - Less than 30% cases

Behavioral abnormality Kyphosis Elevated hepatic transaminase Tapered finger Joint laxity Patent ductus arteriosus Pectus carinatum Hydronephrosis Dental crowding Abnormality of retinal pigmentation Midface retrusion Rocker bottom foot Abnormality of the skeletal system Respiratory insufficiency Anemia Progeroid facial appearance High pitched voice Sensorineural hearing impairment Retrognathia Sclerocornea Hyperkeratosis Tented upper lip vermilion Hydrocephalus Oligodontia Clitoral hypertrophy Cerebellar hypoplasia Microphthalmia Syndactyly Anteriorly placed anus Hypoplasia of the corpus callosum Abnormality of the pinna Anteverted nares Low-set ears Hypertelorism Aplasia/Hypoplasia of the clavicles Wide cranial sutures Neoplasm Thin upper lip vermilion Intestinal malrotation Anonychia Insulin resistance Lipodystrophy Muscular hypotonia Pain Large fontanelles Ventricular septal defect Long philtrum Pachygyria Short clavicles Delayed skeletal maturation Scoliosis Hypopigmentation of the skin Small nail Cerebellar vermis hypoplasia Abnormal cardiac septum morphology High, narrow palate Upslanted palpebral fissure Narrow nasal ridge Underdeveloped nasal alae Intracranial hemorrhage Abnormality of the nail Recurrent respiratory infections Hypodontia Hydrops fetalis Intellectual disability, severe Sparse eyelashes Short chin Type I diabetes mellitus Congestive heart failure Hoarse voice Hypertriglyceridemia Agenesis of permanent teeth Sparse and thin eyebrow Mitral regurgitation Lipoatrophy Hyperhidrosis Everted lower lip vermilion Sparse body hair Scleroderma Premature skin wrinkling Premature graying of hair Delayed eruption of teeth Broad distal phalanx of finger Osteolytic defects of the phalanges of the hand Limb-girdle muscle atrophy Bird-like facies Short proximal phalanx of hallux Mottled pigmentation Loss of subcutaneous adipose tissue in limbs Hematemesis Vertebral compression fractures Breast aplasia Calcinosis Slender long bones with narrow diaphyses Generalized lipodystrophy Hypoplasia of teeth Aplasia of the 1st metacarpal Shortening of all distal phalanges of the toes Osteolytic defects of the distal phalanges of the hand Abnormality of the fingertips Aplasia/Hypoplasia of the hallux Broad secondary alveolar ridge Conductive hearing impairment Hypoplastic facial bones Umbilical hernia Gastroesophageal reflux Mandibular prognathia Brachycephaly Gingival recession Posteriorly rotated ears Abnormality of the scapula Generalized hypotrichosis Intellectual disability, mild Absent sternal ossification Increased adipose tissue around the neck Downslanted palpebral fissures Brachydactyly Nystagmus Bilateral external ear deformity Stiff elbow Foamy urine Progressive clavicular acroosteolysis Increased facial adipose tissue Acroosteolysis of distal phalanges (feet) Foot pain Thin clavicles Abnormal pelvis bone morphology Short thumb Down-sloping shoulders Aplasia of the distal phalanges of the hand Full cheeks Abnormality of skin pigmentation Delayed puberty Nail dystrophy Muscular dystrophy Scarring Paralysis Abnormality of the kidney Proximal muscle weakness Rigidity Narrow nasal base Aplasia/Hypoplasia of the proximal phalanx of the hallux Myopathy Round face Aplasia/hypoplasia of the 1st metatarsal Flexion contracture Acral lentiginous melanoma Aplasia/Hypoplasia of the testes Neoplasm of the oral cavity Premature arteriosclerosis Gastrointestinal carcinoma Neoplasm of the small intestine Subcutaneous calcification Poliosis Abnormal hair whorl Soft tissue sarcoma Aplasia/Hypoplasia of the scapulae Dental malocclusion Narrow nose Hyperglycemia Insulin-resistant diabetes mellitus Tapered toe Arthropathy Aplasia/Hypoplasia of the nails Abnormal parietal bone morphology Spinal rigidity Hypermelanotic macule Delayed cranial suture closure Glucose intolerance Focal segmental glomerulosclerosis Hyperostosis Abnormality of the occipital bone Congenital muscular dystrophy Abnormality of the skin Glomerulosclerosis Hyperinsulinemia Hyperlipidemia Acanthosis nigricans Osteolysis Wormian bones Increased body weight Hyperpigmentation of the skin Abnormality of dental structure Epidermal acanthosis Nephrotic syndrome Abnormality of the cardiovascular system Abnormality of the eye Smooth philtrum Craniosynostosis Inverted nipples Polyhydramnios Agenesis of corpus callosum Ventriculomegaly Macrocephaly Abnormal facial shape Aplasia/Hypoplasia of the nasal bone Abnormality of digit Severe hearing impairment Thin ribs Abnormality of blood and blood-forming tissues Aplasia/Hypoplasia of the thumb Aplastic/hypoplastic lacrimal glands Macrotia Glossoptosis Severe failure to thrive Congenital craniofacial dysostosis Hypoplasia of the abdominal wall musculature Wide nasal ridge Absent distal phalanges Upper eyelid coloboma Recurrent aspiration pneumonia Absence of subcutaneous fat Abnormality of finger Dermal translucency Hypoplasia of the musculature High forehead Hypertrophic cardiomyopathy Hypoplastic scapulae Metatarsus adductus Short ribs Abnormality of pelvic girdle bone morphology Short phalanx of finger Cardiomegaly Abnormality of the urinary system Pyloric stenosis Sparse eyebrow Tetralogy of Fallot Abnormality of dental morphology Neuronal loss in central nervous system Short middle phalanx of finger Flared metaphysis Irritability Dandy-Walker malformation Premature birth Thin vermilion border Toe syndactyly Dolichocephaly Severe global developmental delay Short finger Hip dislocation Microtia Absent thumb Short philtrum Protruding ear Hypoplastic labia majora Chorioretinitis Broad forehead Hypoplasia of the frontal lobes Aplastic clavicle Congenital microcephaly Heterotopia Arrhinencephaly Increased nuchal translucency Short upper lip Hypertrichosis Short palpebral fissure Generalized neonatal hypotonia Aplasia/Hypoplasia of the middle phalanges of the hand Multiple skeletal anomalies Low posterior hairline Recurrent urinary tract infections Renovascular hypertension Renal artery stenosis Oligohydramnios Triangular face Aplasia/Hypoplasia of the distal phalanges of the hand Pulmonary hypoplasia Astigmatism Short toe Abnormality of the foot Synophrys Hypermetropia Platyspondyly Small earlobe Bilateral microphthalmos Deep palmar crease Abnormality of the neck Decreased skull ossification Abnormal eyelid morphology Coronal craniosynostosis Abnormality of the skull Turricephaly Underdeveloped supraorbital ridges Protruding tongue Natal tooth Bilateral cryptorchidism Tricuspid regurgitation Large hands Aortic aneurysm Left ventricular hypertrophy Redundant neck skin Redundant skin Coarse hair Abnormality of vision Abnormality of the metacarpal bones Scrotal hypoplasia Bicuspid aortic valve Generalized hirsutism Low anterior hairline Aplasia/Hypoplasia of the nipples Premature loss of primary teeth Wide anterior fontanel Pneumothorax Small hand Cutaneous melanoma Psychosis Arterial thrombosis Cerebral ischemia Esophageal varix Arteriovenous malformation Pulmonary embolism Disproportionate tall stature Hemiplegia/hemiparesis Ectopia lentis Urticaria Venous thrombosis Anorexia Amblyopia Gastrointestinal hemorrhage Abnormality of amino acid metabolism Recurrent fractures Retinal detachment Arachnodactyly Genu valgum Glaucoma Pectus excavatum Optic atrophy Myopia Seizures Hypoplastic-absent sebaceous glands Aplasia/Hypoplastia of the eccrine sweat glands Periorbital hyperpigmentation Subcutaneous hemorrhage Cleft palate Everted upper lip vermilion Plagiocephaly Erythroid hypoplasia Congenital neutropenia Giant platelets Hypoplasia of the thymus Varicose veins Abnormality of lipid metabolism Iron deficiency anemia Long fingers Unilateral renal agenesis Failure to thrive in infancy Cutis laxa Leukopenia Recurrent bacterial infections Wide nasal bridge Lymphopenia Bronchiectasis Broad thumb Renal agenesis Asthma Neutropenia Pulmonic stenosis Hepatosplenomegaly Pneumonia Clinodactyly Thrombocytopenia Recurrent infections Splenomegaly Periorbital wrinkles Abnormal oral mucosa morphology Intermittent thrombocytopenia Palmar telangiectasia Abnormality of the pulmonary artery Squamous cell carcinoma of the skin Alopecia universalis Aortic root aneurysm Exertional dyspnea Basal cell carcinoma Coronary artery atherosclerosis Emphysema Hypercholesterolemia Aortic valve stenosis Ventricular hypertrophy Plantar telangiectasia Predominantly lower limb lymphedema Papillary renal cell carcinoma Abnormality of the lymphatic system Toenail dysplasia Alopecia totalis Nonimmune hydrops fetalis Hydrocele testis Palpebral edema Cutis marmorata Pleural effusion Lymphedema Telangiectasia Nevus Ascites Erythema Mitral valve calcification Coronary artery stenosis Hypohidrotic ectodermal dysplasia Dysphonia Anhidrotic ectodermal dysplasia Concave nail Anterior hypopituitarism Conical tooth Heat intolerance Anodontia Taurodontia Soft skin Rhinitis Anhidrosis Brittle hair Prominent supraorbital ridges Hypohidrosis Loss of eyelashes Depressed nasal ridge Eczema Ectodermal dysplasia Thick vermilion border Dry skin Respiratory tract infection Prominent forehead Immunodeficiency Frontal bossing Fever Abnormality of the intrahepatic bile duct Aortic atherosclerosis Pulmonary carcinoid tumor Monocytosis Neonatal sepsis Arteriosclerosis Myocardial infarction Sarcoma Laryngomalacia Breast carcinoma Melanoma Macular degeneration Spontaneous abortion Hypergonadotropic hypogonadism Increased bone mineral density Narrow face Abnormality of the hair Skin ulcer Decreased body weight Type II diabetes mellitus Myelodysplasia Decreased testicular size Chest pain Coma Nephropathy Retinal degeneration Leukemia Retinopathy Carcinoma Hypogonadism Rod-cone dystrophy Skeletal muscle atrophy Peripheral neuropathy Visual impairment Abnormality of the voice Polydipsia Hypoplasia of the primary teeth Meningioma Enlarged joints Thyroid carcinoma White forelock Slender build Abnormality of the testis Pili torti Chondrocalcinosis Lack of skin elasticity Peripheral arterial stenosis Abnormality of the cerebral vasculature Osteosarcoma Renal neoplasm Posterior subcapsular cataract Abnormality of the thorax Pulmonary artery stenosis Neoplasm of the lung Alopecia of scalp Subcapsular cataract Ovarian neoplasm Secondary amenorrhea Myeloid leukemia Telangiectasia of the skin Aplasia/Hypoplasia of the skin Decreased fertility Polyphagia Squamous cell carcinoma Polyuria Midline skin dimples over anterior/posterior fontanelles Urethrovaginal fistula Cor triatriatum Hepatic failure Severe muscular hypotonia Hyperbilirubinemia Pointed chin Hypocalcemia Situs inversus totalis Cafe-au-lait spot Cholestasis Hypoplasia of penis Growth hormone deficiency Generalized muscle weakness Abdominal distention Downturned corners of mouth Anal atresia Abnormality of the genitourinary system Malabsorption Dilated cardiomyopathy Small for gestational age Abnormality of the liver Cleft lip Hypothyroidism Severe short stature Clinodactyly of the 5th finger Abnormality of cardiovascular system morphology Dilatation Fatigue Cognitive impairment Strabismus Widely spaced teeth Portal hypertension Abnormality of the female genitalia Lacrimation abnormality Malrotation of small bowel Anasarca Septate vagina Absent lacrimal punctum Increased VLDL cholesterol concentration Colonic diverticula Abnormality of the nares Uterus didelphys Frontal upsweep of hair Skin dimples Aplasia cutis congenita of scalp Abnormal vagina morphology Abnormality of the pancreas Congenital sensorineural hearing impairment Rectovaginal fistula Hypoproteinemia Abnormal hair pattern Calvarial skull defect Fair hair Exocrine pancreatic insufficiency Anal stenosis Facial cleft Hypopituitarism Glycosuria Steatorrhea Hydroureter Dextrocardia Aplasia of the distal phalanx of the hallux


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