Hypertension, and Respiratory tract infection

Diseases related with Hypertension and Respiratory tract infection

In the following list you will find some of the most common rare diseases related to Hypertension and Respiratory tract infection that can help you solving undiagnosed cases.

Top matches:

SICKLE CELL-BETA-THALASSEMIA DISEASE SYNDROME Is also known as hbs-beta-thalassemia syndrome

Related symptoms:

  • Pain
  • Anemia
  • Hypertension
  • Pneumonia
  • Jaundice


SOURCES: ORPHANET MENDELIAN

More info about SICKLE CELL-BETA-THALASSEMIA DISEASE SYNDROME

Karyomegalic interstitial nephritis is a rare, genetic renal disease characterized by slowly progressive, chronic, tubulointerstitial nephritis, leading to end-stage renal disease before the age of 50 years, manifesting with mild proteinuria, glucosuria and, occasionally, urinary sediment abnormalities (mainly hematuria). Mild extrarenal manifestations, such as recurrent upper respiratory tract infections and abnormal liver function tests, may be associated. Renal biopsy reveals severe, chronic, interstitial fibrosis and tubular changes, as well as hallmark karyomegalic tubular epithelial cells which line the proximal and distal tubules and have enlarged, hyperchromatic nuclei.

KARYOMEGALIC INTERSTITIAL NEPHRITIS Is also known as kin|systemic karyomegaly

Related symptoms:

  • Anemia
  • Hypertension
  • Renal insufficiency
  • Recurrent infections
  • Pneumonia


SOURCES: OMIM ORPHANET MENDELIAN

More info about KARYOMEGALIC INTERSTITIAL NEPHRITIS

Trimethylaminuria results from the abnormal presence of large amounts of volatile and malodorous trimethylamine within the body. This chemical, a tertiary aliphatic amine, is excreted in the urine, sweat (ichthyohidrosis), and breath, which take on the offensive odor of decaying fish (Mitchell, 1996).

TRIMETHYLAMINURIA; TMAU Is also known as fish-odor syndrome

Related symptoms:

  • Anemia
  • Hypertension
  • Splenomegaly
  • Depressivity
  • Hyperhidrosis


SOURCES: OMIM ORPHANET MENDELIAN

More info about TRIMETHYLAMINURIA; TMAU

Other less relevant matches:

Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.

IDIOPATHIC PULMONARY FIBROSIS Is also known as cfa|uip|usual interstitial pneumonia|interstitial pneumonitis, usual|idiopathic pulmonary fibrosis, familial|cryptogenic fibrosing alveolitis|fibrosing alveolitis, cryptogenic|fibrocystic pulmonary dysplasia

Related symptoms:

  • Neoplasm
  • Hypertension
  • Fever
  • Respiratory insufficiency
  • Respiratory distress


SOURCES: OMIM ORPHANET MENDELIAN

More info about IDIOPATHIC PULMONARY FIBROSIS

Related symptoms:

  • Failure to thrive
  • Hypertension
  • Respiratory distress
  • Edema
  • Vomiting


SOURCES: OMIM MENDELIAN

More info about INFLAMMATORY SKIN AND BOWEL DISEASE, NEONATAL, 2; NISBD2

Alpha-1-antitrypsin deficiency is a hereditary disease that develops in adulthood and is characterized by chronic liver disorders (cirrhosis), respiratory disorders (emphysema), and rarely panniculitis.

ALPHA-1-ANTITRYPSIN DEFICIENCY Is also known as deficiency in alpa-1-proteinase inhibitor

Related symptoms:

  • Neoplasm
  • Hypertension
  • Hepatomegaly
  • Fatigue
  • Respiratory distress


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about ALPHA-1-ANTITRYPSIN DEFICIENCY

Low match KAPOSI SARCOMA

Kaposi sarcoma (KS) is a rare human herpes virus 8 (HHV-8)-induced endothelial inflammatory neoplasm that develops is various clinically distinct settings, manifesting mostly as cutaneous lesions, or mucosal or visceral involvement.

KAPOSI SARCOMA Is also known as multiple idiopathic pigmented hemangiosarcoma, susceptibility to

Related symptoms:

  • Neoplasm
  • Hypertension
  • Fever
  • Fatigue
  • Edema


SOURCES: OMIM ORPHANET MENDELIAN

More info about KAPOSI SARCOMA

Primary pulmonary arterial hypertension is a rare, often fatal, progressive vascular lung disease characterized by increased pulmonary vascular resistance and sustained elevation of mean pulmonary arterial pressure, leading to right ventricular hypertrophy and right heart failure. Pathologic features include a narrowing and thickening of small pulmonary vessels and plexiform lesions. There is pulmonary vascular remodeling of all layers of pulmonary arterial vessels: intimal thickening, smooth muscle cell hypertrophy or hyperplasia, adventitial fibrosis, and occluded vessels by in situ thrombosis (summary by Machado et al., 2009 and Han et al., 2013).Heterozygous mutations in the BMPR2 gene are found in nearly 70% of families with heritable PPH and in 25% of patients with sporadic disease. The disease is more common in women (female:male ratio of 1.7:1). However, the penetrance of PPH1 is incomplete: only about 10 to 20% of individuals with BMPR2 mutations develop the disease during their lifetime, suggesting that development of the disorder is triggered by other genetic or environmental factors. Patients with PPH1 are less likely to respond to acute vasodilater testing and are unlikely to benefit from treatment with calcium channel blockade (summary by Machado et al., 2009 and Han et al., 2013). Genetic Heterogeneity of Primary Pulmonary HypertensionPPH2 (OMIM ) is caused by mutation in the SMAD9 gene (OMIM ) on chromosome 13q13; PPH3 (OMIM ) is caused by mutation in the CAV1 gene (OMIM ) on chromosome 7q31; and PPH4 (OMIM ) is caused by mutation in the KCNK3 gene (OMIM ) on chromosome 2p23.See {265400} for a possible autosomal recessive form of PPH.Primary pulmonary hypertension may also be found in association with hereditary hemorrhagic telangiectasia type 1 (HHT1 ), caused by mutation in the ENG gene (OMIM ), and HHT2 (OMIM ), caused by mutation in the ACVRL1 (ALK1) gene (OMIM ).

PULMONARY HYPERTENSION, PRIMARY, 1; PPH1 Is also known as pulmonary arterial hypertension|pht|pah

Related symptoms:

  • Pain
  • Hypertension
  • Hepatomegaly
  • Fatigue
  • Respiratory distress


SOURCES: OMIM ORPHANET MENDELIAN

More info about PULMONARY HYPERTENSION, PRIMARY, 1; PPH1

Monocytopenia with susceptibility to infections is a rare, genetic, primary immunodeficiency disorder characterized by profound circulating monocytopenia, B- and NK-cell lymphopenia and severe dentritic cell decrease, which manifests clinically with disseminated mycobacterial and viral infections, as well as opportunistic fungal and parasitic infections and frequent pulmonary alveolar proteinosis. Predisposition to developping myeloid neoplasms is associated.

MONOCYTOPENIA WITH SUSCEPTIBILITY TO INFECTIONS Is also known as dendritic cell, monocyte, b and nk lymphoid deficiency|dcml|dendritic cell, monocyte, b lymphocyte, and natural killer lymphocyte deficiency|monocytopenia with susceptibility to mycobacterial, fungal, and papillomavirus infections and myelodysplasia|monoc

Related symptoms:

  • Hearing impairment
  • Sensorineural hearing impairment
  • Anemia
  • Hypertension
  • Immunodeficiency


SOURCES: OMIM ORPHANET MENDELIAN

More info about MONOCYTOPENIA WITH SUSCEPTIBILITY TO INFECTIONS

Combined immunodeficiency and megaloblastic anemia with or without hyperhomocysteinemia is an inborn error of folate metabolism due to deficiency of methylenetetrahydrofolate dehydrogenase-1. Manifestations may include hemolytic uremic syndrome, macrocytosis, epilepsy, hearing loss, retinopathy, mild mental retardation, lymphopenia involving all subsets, and low T-cell receptor excision circles. Folinic acid supplementation is an effective treatment (summary by Ramakrishnan et al., 2016).

COMBINED IMMUNODEFICIENCY AND MEGALOBLASTIC ANEMIA WITH OR WITHOUT HYPERHOMOCYSTEINEMIA; CIMAH Is also known as methylenetetrahydrofolate dehydrogenase 1 deficiency

Related symptoms:

  • Intellectual disability
  • Seizures
  • Hearing impairment
  • Sensorineural hearing impairment
  • Anemia


SOURCES: OMIM MENDELIAN

More info about COMBINED IMMUNODEFICIENCY AND MEGALOBLASTIC ANEMIA WITH OR WITHOUT HYPERHOMOCYSTEINEMIA; CIMAH

Top 5 symptoms//phenotypes associated to Hypertension and Respiratory tract infection

Symptoms // Phenotype % cases
Pneumonia Common - Between 50% and 80% cases
Anemia Uncommon - Between 30% and 50% cases
Respiratory distress Uncommon - Between 30% and 50% cases
Abnormal lung morphology Uncommon - Between 30% and 50% cases
Pulmonary arterial hypertension Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Hypertension and Respiratory tract infection. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Neoplasm Immunodeficiency Fatigue Abnormality of the liver Carcinoma Cirrhosis Recurrent infections Dyspnea Fever Edema

Rare Symptoms - Less than 30% cases

Vomiting Cyanosis Cough Congestive heart failure Bronchiectasis Right ventricular failure Pain Diarrhea Papule Hepatomegaly Recurrent pneumonia Nephrotic syndrome Hemoptysis Lymphedema Hearing impairment Sensorineural hearing impairment Decreased antibody level in blood Pancytopenia Lymphopenia Leukopenia Weight loss Panniculitis Jaundice Neutropenia Cholestasis Elevated hepatic transaminase Ascites Recurrent respiratory infections Pulmonary capillary hemangiomatosis Elevated right atrial pressure Arterial intimal fibrosis Pulmonary arterial medial hypertrophy Pulmonary aterial intimal fibrosis Pulmonary artery vasoconstriction Neoplasm by anatomical site Increased pulmonary vascular resistance Renal insufficiency Hypothyroidism Leukemia Heart murmur Otitis media Delayed puberty Recurrent otitis media Hemangiomatosis Spontaneous, recurrent epistaxis Vertigo Telangiectasia Chest pain Sudden cardiac death Hypotension Cardiomegaly Epistaxis Ventricular hypertrophy Palpitations Hoarse voice Abnormal tricuspid valve morphology Scleroderma Acrocyanosis Capillary hemangioma Right ventricular hypertrophy Edema of the lower limbs Stroke Abnormal thrombosis Abnormality of the cardiovascular system Spontaneous abortion Bone marrow hypocellularity Thrombocytosis Autoimmunity Retinopathy Metabolic acidosis Bilateral sensorineural hearing impairment Recurrent urinary tract infections Combined immunodeficiency Macrocytic anemia Severe combined immunodeficiency Arthritis Antinuclear antibody positivity Megaloblastic anemia Anisocytosis Hemolytic-uremic syndrome Folate deficiency Asthenia Septic arthritis Decreased methylcobalamin Pallor Acidosis Skin plaque B lymphocytopenia Venous thrombosis Myelodysplasia Myeloid leukemia Acute myeloid leukemia Severe sensorineural hearing impairment Aplastic anemia Recurrent viral infections Verrucae Recurrent fungal infections Intellectual disability, mild Alveolar proteinosis Severe viral infections Chronic myelomonocytic leukemia Monocytopenia Recurrent mycobacterium avium complex infections Abnormal natural killer cell morphology Intellectual disability Seizures Susceptibility to herpesvirus Skin nodule Generalized lymphadenopathy Crackles Interstitial pulmonary abnormality Exertional dyspnea Polycythemia Pulmonary infiltrates Clubbing of fingers Tubular atrophy Pulmonary insufficiency Alveolar cell carcinoma Pulmonary fibrosis Hypocapnia Reticular pattern on pulmonary HRCT Honeycomb lung Ground-glass opacification on pulmonary HRCT Failure to thrive Elevated serum creatinine Tubulointerstitial nephritis Glycosuria Increased antibody level in blood Clubbing Postural instability Respiratory failure Body odor Fish odor Trimethylaminuria Abnormal bleeding Respiratory insufficiency Tachycardia Anxiety Hyperhidrosis Scaling skin Gastroesophageal reflux Scarring Depressivity Splenomegaly Chronic tubulointerstitial nephritis Mild proteinuria Increased blood urea nitrogen Normocytic anemia Nephronophthisis Dehydration Venous insufficiency Sarcoma Skin rash Lymphadenopathy Lymphoma Gastrointestinal hemorrhage Proteinuria Neoplasm of the skin Hemangioma Hypermelanotic macule Abnormality of the kidney Abnormal retinal morphology Macule Abnormality of the gastrointestinal tract Abnormality of the lower limb Lymphoproliferative disorder Abnormality of the spleen Cellular immunodeficiency Alzheimer disease Encephalopathy Neoplasm of the liver Coarctation of aorta Hepatic failure Epidermal acanthosis Long eyelashes Pustule Enlarged kidney Bronchiolitis Recurrent bronchiolitis Nephritis Chronic kidney disease Hepatitis Chronic obstructive pulmonary disease Hematuria Vasculitis Recurrent upper respiratory tract infections Portal hypertension Emphysema Wheezing Stage 5 chronic kidney disease Hepatocellular carcinoma Thiamine-responsive megaloblastic anemia


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