Hypertension, and Paresthesia

Diseases related with Hypertension and Paresthesia

In the following list you will find some of the most common rare diseases related to Hypertension and Paresthesia that can help you solving undiagnosed cases.

Top matches:

Autosomal dominant primary hypomagnesemia with hypocalciuria (ADPHH) is a mild form of familial primary hypomagnesemia (FPH, see this term), characterized by extreme weakness, tetany and convulsions. Secondary disturbances in calcium excretion are observed.

AUTOSOMAL DOMINANT PRIMARY HYPOMAGNESEMIA WITH HYPOCALCIURIA Is also known as isolated renal magnesium wasting|isolated autosomal dominant hypomagnesemia|magnesium wasting, renal|homg2|renal hypomagnesemia type 2|magnesium loss, isolated renal

Related symptoms:

  • Seizures
  • Hypertension
  • Fatigue
  • Renal insufficiency
  • Muscle cramps


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about AUTOSOMAL DOMINANT PRIMARY HYPOMAGNESEMIA WITH HYPOCALCIURIA

Porphyria of doss or deficiency of delta-aminolevulinic acid dehydratase (DALAD) is an extremely rare form of acute hepatic porphyria (see this term) characterized by neuro-visceral attacks without cutaneous manifestations.

PORPHYRIA DUE TO ALA DEHYDRATASE DEFICIENCY Is also known as porphyria due to alad deficiency|doss porphyria|delta-aminolevulinate dehydratase deficiency|alad porphyria|porphyria, alad|porphyria of doss|alad deficiency|porphyria due to delta-aminolevulinate dehydratase deficiency|porphobilinogen synthase deficiency

Related symptoms:

  • Seizures
  • Generalized hypotonia
  • Failure to thrive
  • Muscular hypotonia
  • Pain


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about PORPHYRIA DUE TO ALA DEHYDRATASE DEFICIENCY

AMYLOIDOSIS, FAMILIAL VISCERAL Is also known as german type amyloidosis|amyloidosis, systemic nonneuropathic|amyloidosis viii|amyloidosis, familial renal|ostertag type amyloidosis

Related symptoms:

  • Hearing impairment
  • Neoplasm
  • Pain
  • Hypertension
  • Peripheral neuropathy


SOURCES: ORPHANET OMIM MENDELIAN

More info about AMYLOIDOSIS, FAMILIAL VISCERAL

Other less relevant matches:

Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN, see this term) characterized by a sustained elevation of platelet number (> 450 x 109/L) with a tendency for thrombosis and hemorrhage.

ESSENTIAL THROMBOCYTHEMIA Is also known as thrombocytosis 1|essential thrombocytosis|et

Related symptoms:

  • Pain
  • Hypertension
  • Hepatomegaly
  • Abnormality of the skeletal system
  • Respiratory distress


SOURCES: ORPHANET OMIM MENDELIAN

More info about ESSENTIAL THROMBOCYTHEMIA

Acute intermittent porphyria is the most frequent and the most severe form of the acute hepatic porphyrias (see this term). It is characterized by the occurrence of neuro-visceral attacks without cutaneous manifestations.

ACUTE INTERMITTENT PORPHYRIA Is also known as ups deficiency|porphyria, swedish type|pbgd deficiency|porphobilinogen deaminase deficiency|uroporphyrinogen synthase deficiency

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Muscle weakness
  • Pain


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about ACUTE INTERMITTENT PORPHYRIA

Hereditary coproporphyria is a form of acute hepatic porphyria (see this term) characterized by the occurrence of neuro-visceral attacks and, more rarely, by the presence of cutaneous lesions.

HEREDITARY COPROPORPHYRIA Is also known as cpox deficiency|cpx deficiency|coproporphyrinogen oxidase deficiency|cpo deficiency

Related symptoms:

  • Seizures
  • Muscle weakness
  • Pain
  • Anemia
  • Hypertension


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about HEREDITARY COPROPORPHYRIA

Multiple symmetric lipomatosis (MSL) is a rare subcutaneous tissue disease characterized by growth of symmetric non-encapsulated masses of adipose tissue mostly around the face and neck with variable clinical repercussions (e.g. reduced neck mobility, compression of respiratory structures).

MULTIPLE SYMMETRIC LIPOMATOSIS Is also known as launois-bensaude lipomatosis|familial benign cervical lipomatosis|madelung disease|cephalothoracic lipodystrophy|lipomatosis, familial benign cervical|lipodystrophy, cephalothoracic

Related symptoms:

  • Neoplasm
  • Pain
  • Anemia
  • Hypertension
  • Peripheral neuropathy


SOURCES: ORPHANET OMIM MENDELIAN

More info about MULTIPLE SYMMETRIC LIPOMATOSIS

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a rare neurodegenerative disorder characterized by adult-onset progressive intention tremor and gait ataxia.

FRAGILE X-ASSOCIATED TREMOR/ATAXIA SYNDROME Is also known as fxtas syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Hearing impairment
  • Ataxia


SOURCES: MESH OMIM ORPHANET MENDELIAN

More info about FRAGILE X-ASSOCIATED TREMOR/ATAXIA SYNDROME

Gitelman syndrome is an autosomal recessive renal tubular salt-wasting disorder characterized by hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria. It is the most common renal tubular disorder among Caucasians (prevalence of 1 in 40,000). Most patients have onset of symptoms as adults, but some can present in childhood. Clinical features include transient periods of muscle weakness and tetany, abdominal pains, and chondrocalcinosis (summary by Glaudemans et al., 2012). Gitelman syndrome is sometimes referred to as a mild variant of classic Bartter syndrome (OMIM ).For a discussion of genetic heterogeneity of Bartter syndrome, see {607364}.

GITELMAN SYNDROME; GTLMNS Is also known as hypomagnesemia-hypokalemia, primary renotubular, with hypocalciuria|potassium and magnesium depletion

Related symptoms:

  • Seizures
  • Short stature
  • Generalized hypotonia
  • Ataxia
  • Growth delay


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about GITELMAN SYNDROME; GTLMNS

Emery-Dreifuss muscular dystrophy is characterized classically by the triad of weakness of the shoulder and pelvic girdle muscles, contractures of the elbows, neck, and Achilles tendon, and cardiac involvement, most commonly arrhythmias (summary by Jimenez-Escrig et al., 2012).For a discussion of genetic heterogeneity of EDMD, see {310300}.

AUTOSOMAL RECESSIVE EMERY-DREIFUSS MUSCULAR DYSTROPHY Is also known as edmd3

Related symptoms:

  • Intellectual disability
  • Scoliosis
  • Micrognathia
  • Muscle weakness
  • Abnormal facial shape


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about AUTOSOMAL RECESSIVE EMERY-DREIFUSS MUSCULAR DYSTROPHY

Top 5 symptoms//phenotypes associated to Hypertension and Paresthesia

Symptoms // Phenotype % cases
Pain Common - Between 50% and 80% cases
Seizures Common - Between 50% and 80% cases
Muscle weakness Uncommon - Between 30% and 50% cases
Tachycardia Uncommon - Between 30% and 50% cases
Abdominal pain Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Hypertension and Paresthesia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Peripheral neuropathy Hepatosplenomegaly Vomiting Diarrhea Arthralgia Hepatomegaly Arrhythmia Anxiety Constipation Anemia Splenomegaly Respiratory paralysis Nephropathy Psychosis Vertigo Intellectual disability Depressivity Paralysis Nausea and vomiting Nausea Hypotension Gait disturbance Hyponatremia Myalgia Polyneuropathy Behavioral abnormality Muscle cramps

Rare Symptoms - Less than 30% cases

Paraparesis Hallucinations Cutaneous photosensitivity Urinary incontinence Generalized muscle weakness Hypokalemia Agitation Pulmonary embolism Hypomagnesemia Chondrocalcinosis Dysesthesia Hypocalciuria Global developmental delay Renal magnesium wasting Apathy Ileus Insomnia Hypothyroidism Proximal muscle weakness Ataxia Pollakisuria Fatigue Reduced tendon reflexes Joint stiffness Renal insufficiency Generalized hypotonia Palpitations Confusion Irritability Acute episodes of neuropathic symptoms Red urine Delirium Myocardial infarction Postural instability Neoplasm Fever Failure to thrive Hearing impairment Elevated urinary delta-aminolevulinic acid Muscular hypotonia Abdominal colic Weight loss Hemolytic anemia Inertia Subcortical dementia Impaired tandem gait Short stature Retrocollis Growth delay Erythema Delayed puberty Obsessive-compulsive trait Generalized amyotrophy Inflammatory abnormality of the skin Dehydration Impaired distal vibration sensation Cardiac arrest Ventricular tachycardia Ventricular arrhythmia Hyperkinesis Hypercalciuria Polydipsia Polyuria Blurred vision Prolonged QT interval Permanent atrial fibrillation Rhabdomyolysis Limb-girdle muscle atrophy Episodic fever Diffuse cerebellar atrophy Ventricular escape rhythm Hyperventilation Pelvic girdle muscle atrophy Mask-like facies Postural tremor Obsessive-compulsive behavior Premature ovarian insufficiency Dysdiadochokinesis Spastic paraparesis Abnormal autonomic nervous system physiology Global brain atrophy Horizontal nystagmus Limb ataxia Intention tremor Bradykinesia Memory impairment Brain atrophy Impotence Bowel incontinence Abnormal nerve conduction velocity Olivopontocerebellar atrophy Abnormality of brainstem morphology Poor fine motor coordination Saccadic smooth pursuit Kinetic tremor Disinhibition Astrocytosis Diffuse cerebral atrophy Abnormality of the thyroid gland Action tremor Urinary bladder sphincter dysfunction Proximal upper limb amyotrophy Bipolar affective disorder Atrophy/Degeneration affecting the brainstem Resting tremor Absent muscle fiber emerin Alkalosis Renal salt wasting Waddling gait Kyphosis Ankle contracture Sprengel anomaly Rimmed vacuoles Obesity Pectus excavatum Elevated serum creatine phosphokinase Hyperlordosis Muscular dystrophy Dilated cardiomyopathy Limb muscle weakness Lower limb muscle weakness Ichthyosis Sudden cardiac death Lumbar hyperlordosis Decreased cervical spine flexion due to contractures of posterior cervical muscles Back pain Toe walking Congenital muscular dystrophy Myotonia Spinal rigidity Limb-girdle muscular dystrophy Lipodystrophy Atrioventricular block Hypertriglyceridemia EMG: myopathic abnormalities Scapular winging Elbow flexion contracture Diplopia Abnormal lung morphology Atrial fibrillation Progeroid facial appearance Myopathy Restrictive ventilatory defect Hypochloremia Enuresis Tetany Proximal muscle weakness in upper limbs Metabolic alkalosis Increased circulating renin level Periodic paralysis Hypovolemia Hypokalemic alkalosis Hypokalemic metabolic alkalosis Proximal lower limb amyotrophy Nocturia Renal potassium wasting Shoulder girdle muscle atrophy Increased LDL cholesterol concentration Type 1 muscle fiber atrophy Shoulder girdle muscle weakness Ptosis Progressive cerebellar ataxia Skeletal muscle atrophy Limb-girdle muscle weakness Achilles tendon contracture Flexion contracture Decreased HDL cholesterol concentration Increased connective tissue Supraventricular arrhythmia Abnormal facial shape Micrognathia Hyporeflexia of lower limbs Proximal muscle weakness in lower limbs Scoliosis Pelvic girdle muscle weakness Salt craving Axonal degeneration Parkinsonism Bloody diarrhea Myeloid leukemia Thrombocytosis Transient ischemic attack Acrocyanosis Gangrene Acute leukemia Abnormality of the cerebral vasculature Arterial thrombosis Abnormal thrombocyte morphology Impaired platelet aggregation Myeloproliferative disorder Amaurosis fugax Abnormality of bone marrow cell morphology Myelofibrosis Abnormal platelet morphology Leukocytosis Decreased mean platelet volume Abnormal platelet aggregation Increased megakaryocyte count Intellectual disability, mild Hyperhidrosis Carcinoma Lethargy Stage 5 chronic kidney disease Coma Abdominal distention Anorexia Hyperlipidemia Cranial nerve paralysis Hepatocellular carcinoma Prolonged bleeding time Myelodysplasia Urinary retention Urticaria Chronic fatigue Respiratory insufficiency Sensory neuropathy Hemiparesis Motor axonal neuropathy Wrist drop Cardiomyopathy Edema Glaucoma Proteinuria Skin rash Hematuria Nephrotic syndrome Cholestasis Amyloidosis Venous thrombosis Respiratory distress Lymphoma Chest pain Bruising susceptibility Leukemia Dyspnea Headache Abnormality of the skeletal system Optic neuropathy Generalized amyloid deposition Renal amyloidosis Albuminuria Restrictive cardiomyopathy Drusen Papilledema Dysuria Diaphragmatic paralysis Abnormal cerebellum morphology Tremor Macrocytic anemia Lipoma Oligomenorrhea Gout Hyperlipoproteinemia Alcoholism Decreased LDL cholesterol concentration Neuropathic arthropathy Increased HDL cholesterol concentration Abnormal adipose tissue morphology Nystagmus Cognitive impairment Hyperreflexia Dysarthria Dysphagia Multiple lipomas Cerebellar atrophy Hyporeflexia Dementia Cerebral cortical atrophy Gait ataxia Autism Rigidity Aggressive behavior Mental deterioration Stroke Abnormality of the cerebral white matter Abnormality of movement Dysmetria Distal sensory impairment Arthropathy Coronary artery atherosclerosis Abnormal urinary color Orthostatic hypotension Psychotic episodes Hypertensive crisis Paralytic ileus Abnormality of metabolism/homeostasis Areflexia Acidosis Jaundice Elevated hepatic transaminase Pruritus Metabolic acidosis Abnormal blistering of the skin Hypertrichosis Thin skin Hypermelanotic macule Prolonged neonatal jaundice Oral-pharyngeal dysphagia Diabetes mellitus Abnormality of mitochondrial metabolism Ragged-red muscle fibers Hoarse voice Insulin resistance Abnormality of the skin Abnormality of the liver Pes cavus Fragile skin Babinski sign Compensated hemolytic anemia Congenital hemolytic anemia Paranoia Auditory hallucinations Visual hallucinations Restricted neck movement due to contractures


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