Hypertension, and Eosinophilia
Diseases related with Hypertension and Eosinophilia
In the following list you will find some of the most common rare diseases related to Hypertension and Eosinophilia that can help you solving undiagnosed cases.
Severe combined immunodeficiency (SCID) due to adenosine deaminase (ADA) deficiency is a form of SCID characterized by profound lymphopenia and very low immunoglobulin levels of all isotypes resulting in severe and recurrent opportunistic infections.
SEVERE COMBINED IMMUNODEFICIENCY DUE TO ADENOSINE DEAMINASE DEFICIENCY Is also known as ada deficiency|ada-scid|scid due to adenosine deaminase deficiency|scid due to ada deficiency|scid due to ada deficiency, early-onsetRelated symptoms:
- Global developmental delay
- Failure to thrive
- Abnormality of the skeletal system
More info about SEVERE COMBINED IMMUNODEFICIENCY DUE TO ADENOSINE DEAMINASE DEFICIENCY
Congenital cataract - hypertrophic cardiomyopathy - mitochrondrial myopathy (CCM) is a mitochondrial disease (see this term) characterized by cataracts, hypertrophic cardiomyopathy, muscle weakness and lactic acidosis after exercise.
CONGENITAL CATARACT-HYPERTROPHIC CARDIOMYOPATHY-MITOCHONDRIAL MYOPATHY SYNDROME Is also known as mtdps10|sengers syndrome|cardiomyopathy and cataract|mitochondrial dna depletion syndrome 10 (cardiomyopathic type)Related symptoms:
- Intellectual disability
- Generalized hypotonia
- Growth delay
More info about CONGENITAL CATARACT-HYPERTROPHIC CARDIOMYOPATHY-MITOCHONDRIAL MYOPATHY SYNDROME
Medium match HOLT-ORAM SYNDROME; HOS
Holt-Oram syndrome is an autosomal dominant disorder characterized by abnormalities of the upper limbs and shoulder girdle, associated with a congenital heart lesion. The typical combination is considered to be a triphalangeal thumb with a secundum atrial septal defect (ASD), but there is a great range in the severity of both the heart and skeletal lesions (summary by Hurst et al., 1991).
HOLT-ORAM SYNDROME; HOS Is also known as atriodigital dysplasia|heart-hand syndrome|hos1Related symptoms:
- Intellectual disability
- Short stature
- Failure to thrive
- Cleft palate
More info about HOLT-ORAM SYNDROME; HOS
Other less relevant matches:
Medium match SARCOIDOSIS
Sarcoidosis is a multisystemic disorder of unknown cause characterized by the formation of immune granulomas in involved organs.
SARCOIDOSIS Is also known as boeck sarcoid|besnier-boeck-schaumann disease|sarcoidosis|boeck's sarcoidRelated symptoms:
- Visual impairment
More info about SARCOIDOSIS
Low match MASTOCYTOSIS, CUTANEOUS; MASTC
Mastocytosis, or mast cell disease, is a heterogeneous group of clinical disorders characterized by the abnormal accumulation of mast cells in various tissues, especially in the skin and hematopoietic organs. Mastocytosis usually appears in infancy or early adulthood. In most pediatric cases, the disease is limited to the skin, but it can be associated with systemic symptoms due to the release of mediators from mast cells, even when there is no systemic infiltration. It usually has a good prognosis, with substantial improvement or spontaneous resolution before puberty. In rare cases, the disease may remain active through adolescence as a systemic adult mastocytosis. Cutaneous mastocytosis is characterized by macules, papules, nodules, or diffuse infiltration of the skin, often associated with localized hyperpigmentation. Gentle rubbing of the lesions induces histamine release from mechanically activated mast cells, causing local wheals, erythema, and often pruritus, a phenomenon termed the 'Darier sign.' In contrast to childhood-onset mastocytosis, adult-onset mastocytosis often persists for the lifetime of the patient and is also more likely to be a severe and systemic disease involving numerous organs. In some cases, it is associated with a clonal hematologic non-mast-cell lineage disease, such as a myelodysplastic or myeloproliferative disorder. Adult-onset mastocytosis can also lead to the rare mast cell leukemia, which carries a high risk of mortality (summary by Bodemer et al., 2010 and Kambe et al., 2010).
MASTOCYTOSIS, CUTANEOUS; MASTC Is also known as mastocytosis, maculopapular cutaneous|mastocytosis, diffuse cutaneous|urticaria pigmentosaRelated symptoms:
More info about MASTOCYTOSIS, CUTANEOUS; MASTC
Low match ESSENTIAL THROMBOCYTHEMIA
Essential thrombocythemia (ET) is a myeloproliferative neoplasm (MPN, see this term) characterized by a sustained elevation of platelet number (> 450 x 109/L) with a tendency for thrombosis and hemorrhage.
ESSENTIAL THROMBOCYTHEMIA Is also known as thrombocytosis 1|essential thrombocytosis|etRelated symptoms:
- Abnormality of the skeletal system
- Respiratory distress
More info about ESSENTIAL THROMBOCYTHEMIA
Low match ACQUIRED PARTIAL LIPODYSTROPHY
Acquired partial lipodystrophy, or Barraquer-Simons syndrome, is characterised by the association of lipoatrophy of the upper part of the body and lipohypertrophy of the thighs.
ACQUIRED PARTIAL LIPODYSTROPHY Is also known as apld, susceptibility to|progressive cephalothoracic lipodystrophy|barraquer-simons syndrome|lipodystrophy, cephalothoracic type|lipodystrophy, partial, progressiveRelated symptoms:
- Intellectual disability
- Hearing impairment
More info about ACQUIRED PARTIAL LIPODYSTROPHY
Low match PRIMARY SCLEROSING CHOLANGITIS
Primary sclerosing cholangitis (PSC) is a rare, slowly progressive liver disease characterized by inflammation and destruction of the intra- and/or extra-hepatic bile ducts that lead to cholestasis, liver fibrosis, liver cirrhosis and ultimately liver failure.
PRIMARY SCLEROSING CHOLANGITIS Is also known as pscRelated symptoms:
More info about PRIMARY SCLEROSING CHOLANGITIS
Low match POLYCYTHEMIA VERA
Polycythemia vera (PV) is an acquired myeloproliferative disorder characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production, frequently associated with uncontrolled white blood cell and platelet production.
POLYCYTHEMIA VERA Is also known as polycythemia rubra vera|acquired primary erythrocytosis|prv|vaquez disease|osler-vaquez disease|pvRelated symptoms:
- Visual impairment
More info about POLYCYTHEMIA VERA
Low match VASCULITIS DUE TO ADA2 DEFICIENCY
Vasculitis due to ADA2 deficiency is a rare, genetic, systemic and rheumatologic disease due to adenosine deaminase-2 inactivating mutations, combining variable features of autoinflammation, vasculitis, and a mild immunodeficiency. Variable clinical presentation includes chronic or recurrent systemic inflammation with fever, livedo reticularis or racemosa, early-onset ischemic or hemorrhagic strokes, peripheral neuropathy, abdominal pain, hepatosplenomegaly, portal hypertension, cutaneous polyarteritis nodosa, variable cytopenia and immunoglobulin deficiency.
VASCULITIS DUE TO ADA2 DEFICIENCY Is also known as ada2 deficiency|vasculitis due to dada2Related symptoms:
- Peripheral neuropathy
More info about VASCULITIS DUE TO ADA2 DEFICIENCY
Top 5 symptoms//phenotypes associated to Hypertension and Eosinophilia
|Symptoms // Phenotype||% cases|
|Hepatomegaly||Common - Between 50% and 80% cases|
|Splenomegaly||Common - Between 50% and 80% cases|
|Fatigue||Common - Between 50% and 80% cases|
|Hepatosplenomegaly||Common - Between 50% and 80% cases|
|Headache||Common - Between 50% and 80% cases|
Other less frequent symptoms
Patients with Hypertension and Eosinophilia. may also develop some of the following symptoms:
Uncommon Symptoms - Between 30% and 50% casesThrombocytopenia Pain Anemia Weight loss Portal hypertension Abdominal pain Respiratory distress Erythema Fever Allergy Pruritus Stroke Failure to thrive Arthralgia Congestive heart failure Papule Leukopenia Dyspnea Lymphadenopathy Seizures Intellectual disability Leukemia Thrombocytosis Acute leukemia Myeloproliferative disorder Asthma Autoimmunity Gastrointestinal hemorrhage Leukocytosis Immunodeficiency Diarrhea Abnormality of the skeletal system Bruising susceptibility
Rare Symptoms - Less than 30% casesPulmonary embolism Arterial thrombosis Cirrhosis Myelodysplasia Myelofibrosis Epistaxis Venous thrombosis Glaucoma Respiratory insufficiency Myocardial infarction Scarring Osteopenia Hemiparesis Elevated hepatic transaminase Abnormality of the liver Premature ovarian insufficiency Cataract Edema Renal insufficiency Arrhythmia Abnormal eosinophil morphology Visual impairment Alopecia Heart block Ascites Arthritis Increased megakaryocyte count Vertigo Nausea Peripheral neuropathy Inflammation of the large intestine Chest pain Cerebral hemorrhage Recurrent infections Erythema nodosum Immune dysregulation Hepatitis Purpura Uveitis Recurrent upper respiratory tract infections Combined immunodeficiency Elevated erythrocyte sedimentation rate Pleural effusion Myopathy Osteolysis Pancytopenia Sudden cardiac death Myalgia Neoplasm Osteoporosis Skin rash Anaphylactic shock Cutaneous mastocytosis Dermatographic urticaria Abnormal conjunctiva morphology Mastocytosis Food intolerance Abnormality of the gastric mucosa Telangiectasia macularis eruptiva perstans Vitreous floaters Impaired temperature sensation Asthenia Immunologic hypersensitivity Chronic leukemia Abnormal salivary gland morphology Paresthesia Iridocyclitis Hypersplenism Anterior uveitis Dacryocystitis Chorioretinitis Lymphoma Malabsorption Abnormality of the adrenal glands Abnormality of the lymph nodes Skin plaque Generalized lymphadenopathy Prolonged bleeding time Myeloid leukemia Ichthyosis Gastrointestinal stroma tumor Generalized osteosclerosis Transient ischemic attack Non-caseating epithelioid cell granulomatosis Pulmonary granulomatosis Tachycardia Vitreous snowballs Enlarged lacrimal glands Recurrent fractures Maculopapular exanthema Abnormality of the nasal mucosa Hypotension Abnormal blistering of the skin Increased T cell count Abnormal cardiac ventricular function Parotitis Abnormal liver parenchyma morphology Telangiectasia Bone pain Abnormal trabecular meshwork morphology Shock Flushing Abnormality of blood and blood-forming tissues Hypermelanotic macule Loss of consciousness Urticaria Nausea and vomiting Bone marrow hypocellularity Abnormality of T cell physiology Vitritis Gastroesophageal reflux Abnormal reproductive system morphology Abnormality of skin morphology Posterior vitreous detachment Enlargement of parotid gland Sarcoma Hirsutism Acrocyanosis Neoplasm of the gallbladder Abnormal thrombosis Cerebral ischemia Angina pectoris Deep venous thrombosis Gingival bleeding Thromboembolism Polycythemia Tinnitus Adenocarcinoma of the large intestine Dilated superficial abdominal veins Recurrent systemic pyogenic infections Abnormal large intestine physiology Erythroid hyperplasia Spider hemangioma Polyclonal elevation of IgM Elevated alkaline phosphatase of hepatic origin Palmar telangiectasia Abnormal biliary tract morphology Chronic hepatic failure Vitamin K deficiency Vitamin A deficiency Cholangiocarcinoma Vitamin E deficiency Sclerosing cholangitis Intermittent claudication Portal vein thrombosis Histiocytosis Hemiplegia Retinal arterial occlusion Lupus anticoagulant Pure red cell aplasia Panniculitis Antiphospholipid antibody positivity Granulocytopenia Hypercoagulability Raynaud phenomenon Aphasia Agitation Cutis marmorata Ischemic stroke Increased hemoglobin Vasculitis Foot dorsiflexor weakness Decreased antibody level in blood Paraplegia Ophthalmoplegia Dilatation Optic atrophy Ataxia Elevated leukocyte alkaline phosphatase Increased red blood cell mass Budd-Chiari syndrome Increased hematocrit Vitamin D deficiency Prolonged prothrombin time Gangrene Cystoid macular edema Glomerulonephritis Lipodystrophy Polycystic ovaries Generalized hirsutism Insulin resistance Hypertrichosis Hypertriglyceridemia Nephrotic syndrome Nephropathy Hematuria Hepatic steatosis Proteinuria Glomerulopathy Diabetes mellitus Hearing impairment Abnormal platelet aggregation Decreased mean platelet volume Abnormal platelet morphology Bloody diarrhea Abnormality of bone marrow cell morphology Amaurosis fugax Impaired platelet aggregation Abnormal thrombocyte morphology Abnormality of the cerebral vasculature Lipoatrophy Abnormality of lipid metabolism Cholangitis Pancreatitis Cholestatic liver disease Ulcerative colitis Acute hepatic failure Hepatocellular carcinoma Thyroiditis Amyloidosis Celiac disease Abnormality of the thyroid gland Generalized amyotrophy Cholelithiasis Hypoalbuminemia Type I diabetes mellitus Microscopic hematuria Hepatic fibrosis Cholestasis Jaundice Encephalopathy Depressivity Loss of subcutaneous adipose tissue from upper limbs Progressive loss of facial adipose tissue Loss of truncal subcutaneous adipose tissue Decreased serum complement C3 Membranoproliferative glomerulonephritis Lymphocytosis Progeroid facial appearance Abnormality of the cerebrospinal fluid Global developmental delay Chylothorax Aciduria Abnormality of mitochondrial metabolism Abnormal electroretinogram Easy fatigability Ragged-red muscle fibers Tachypnea Corneal dystrophy Exercise intolerance Cardiac arrest Pulmonary arterial hypertension Esotropia Increased serum lactate Mitochondrial myopathy Generalized muscle weakness Lactic acidosis Congenital cataract Feeding difficulties in infancy Mental deterioration Hypertrophic cardiomyopathy Acidosis Cerebellar hypoplasia Cardiomyopathy Myopia Hypoplasia of the brainstem Meningocele Muscular hypotonia Depletion of mitochondrial DNA in muscle tissue Abnormality of cardiovascular system morphology Syndactyly Vomiting Atrial septal defect Ventricular septal defect Frontal bossing Depressed nasal bridge Cleft palate Micrognathia Short stature Abnormal muscle fiber protein expression Cardiorespiratory arrest Exercise-induced lactic acidemia Infantile axial hypotonia Inferior vermis hypoplasia Fatty replacement of skeletal muscle Decreased activity of mitochondrial respiratory chain Abnormal myelination 3-Methylglutaconic aciduria Skeletal myopathy Organic aciduria Right ventricular hypertrophy Motor delay Muscle weakness Clinodactyly Recurrent pneumonia B-cell lymphoma Recurrent lower respiratory tract infections Severe combined immunodeficiency Autoimmune thrombocytopenia IgA deficiency Autoimmune hemolytic anemia Malnutrition Abnormality of pelvic girdle bone morphology Leukoencephalopathy Recurrent bacterial infections Lymphopenia Verrucae Sinusitis Chronic diarrhea Recurrent otitis media Inflammatory abnormality of the skin Sepsis Neutropenia Platyspondyly Respiratory tract infection Recurrent respiratory infections Pneumonia Recurrent viral infections IgM deficiency Strabismus Absence of lymph node germinal center Nystagmus Growth delay Generalized hypotonia Absent specific antibody response Reduced red cell adenosine deaminase activity Anti-thyroid peroxidase antibody positivity Lack of T cell function Severe B lymphocytopenia Abnormality of humoral immunity Absent tonsils Immunoglobulin IgG2 deficiency Cellular immunodeficiency Recurrent opportunistic infections Cortical sclerosis Aplasia of the thymus Anterior rib cupping Recurrent fungal infections Diffuse mesangial sclerosis B lymphocytopenia Decrease in T cell count Pulmonary insufficiency Increased IgE level Pectus excavatum Patent ductus arteriosus Vitreous hemorrhage Subcutaneous nodule Epiphora Hypercalcemia Hypercalciuria Ventricular tachycardia Nephrocalcinosis Decreased liver function Hyperpigmentation of the skin Anorexia Bronchiectasis Nephrolithiasis Abnormal lung morphology Emphysema Palpitations Syncope Hypopigmentation of the skin Hemolytic anemia Hepatic failure Cough Facial palsy Proximal muscle weakness Photophobia Hypothyroidism Diabetes insipidus Pulmonary fibrosis Skeletal muscle atrophy Hypothermia Abnormality of the pleura Pneumothorax Anterior synechiae of the anterior chamber Night sweats Skin nodule Bone cyst Macular edema Upper airway obstruction Abnormality of the gastrointestinal tract Tubulointerstitial nephritis Increased CSF protein Blurred vision Joint swelling Optic neuropathy Hemoptysis Keratoconjunctivitis sicca Hyperuricemia Hyperthyroidism Abnormality of the musculature Interstitial pulmonary abnormality Chorioretinal atrophy Increased antibody level in blood Blindness Quadricuspid aortic valve Abnormal heart morphology Finger clinodactyly Hypoplastic left heart Right bundle branch block Bundle branch block Menorrhagia Hypoplasia of the ulna Bowing of the legs Triphalangeal thumb Atrioventricular block Hypoplasia of the radius Aortic regurgitation Horseshoe kidney Limited elbow extension Aortic valve stenosis Bradycardia Abnormal vertebral morphology Short thumb Atrial fibrillation Coarctation of aorta Mitral valve prolapse Abnormality of the cardiovascular system Abnormal cardiac septum morphology Polydactyly Petechiae Absent thumb Patellar subluxation Total anomalous pulmonary venous return Lactose intolerance Tibial torsion Aplasia of the pectoralis major muscle Mesoaxial polydactyly Short digit Aplasia of the ulna Partial duplication of thumb phalanx Abnormality of the carpal bones Small thenar eminence Hematemesis Phocomelia Atrioventricular canal defect Anomalous pulmonary venous return Complete atrioventricular canal defect Ecchymosis Secundum atrial septal defect Down-sloping shoulders Truncus arteriosus Short clavicles Thoracic scoliosis Absent radius Oligodactyly Short humerus Central retinal artery occlusion
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