Hypertension, and Dementia

Diseases related with Hypertension and Dementia

In the following list you will find some of the most common rare diseases related to Hypertension and Dementia that can help you solving undiagnosed cases.

Top matches:

A degenerative disease of the brain characterized by the insidious onset of dementia. Impairment of memory, judgment, attention span, and problem solving skills are followed by severe apraxia and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of senile plaques, neurofibrillary tangles, and neuropil threads. [HPO:probinson]

ALZHEIMER DISEASE 2; AD2 Is also known as alzheimer disease associated with apoe4|alzheimer disease 2, late-onset

Related symptoms:

  • Hypertension
  • Dementia
  • Diabetes mellitus
  • Stroke
  • Parkinsonism


SOURCES: OMIM MESH MENDELIAN

More info about ALZHEIMER DISEASE 2; AD2

Hereditary cerebral hemorrhage with amyloidosis, Dutch type (HCHWA-D) is a form of HCHWA (see this term), a group of familial central nervous system disorders, characterized by severe cerebral amyloid angiopathy (CAA), hemorrhagic and non-hemorrhagic strokes and dementia.

ABETA AMYLOIDOSIS, DUTCH TYPE Is also known as hchwad|amyloidosis, hereditary, with cerebral hemorrhage, dutch variant|hereditary cerebral hemorrhage with amyloidosis, dutch type|cerebral amyloid angiopathy, app-related, iowa variant|cerebral amyloid angiopathy, app-related, italian variant|hchwa, dut

Related symptoms:

  • Seizures
  • Cognitive impairment
  • Hypertension
  • Behavioral abnormality
  • Headache


SOURCES: ORPHANET OMIM MENDELIAN

More info about ABETA AMYLOIDOSIS, DUTCH TYPE

Fatal familial insomnia (FFI) is a very rare form of prion disease (see this term) characterized by subacute onset of insomnia showing as a reduced overall sleep time, autonomic dysfunction, and motor disturbances.

FATAL FAMILIAL INSOMNIA Is also known as insomnia, fatal familial

Related symptoms:

  • Seizures
  • Ataxia
  • Nystagmus
  • Spasticity
  • Hypertension


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about FATAL FAMILIAL INSOMNIA

Other less relevant matches:

Low match CARASIL

CARASIL is a hereditary cerebral small vessel disease characterized by early-onset gait disturbances, premature scalp alopecia, ischemic stroke, acute mid to lower back pain and progressive cognitive disturbances leading to severe dementia.

CARASIL Is also known as cerebrovascular disease with thin skin, alopecia, and disc disease|subcortical vascular encephalopathy, progressive|maeda syndrome|cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy

Related symptoms:

  • Ataxia
  • Nystagmus
  • Pain
  • Spasticity
  • Cognitive impairment


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about CARASIL

Sneddon's syndrome (SS) is a rare non-inflammatory thrombotic vasculopathy characterized by the combination of cerebrovascular disease with livedo racemosa.

SNEDDON SYNDROME Is also known as livedo reticularis-cerebrovascular accident syndrome|livedo racemosa-cerebrovascular accident syndrome|livedo reticularis and cerebrovascular accidents|ehrmann-sneddon syndrome

Related symptoms:

  • Seizures
  • Muscle weakness
  • Pain
  • Visual impairment
  • Motor delay


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about SNEDDON SYNDROME

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a rare neurodegenerative disorder characterized by adult-onset progressive intention tremor and gait ataxia.

FRAGILE X-ASSOCIATED TREMOR/ATAXIA SYNDROME Is also known as fxtas syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Hearing impairment
  • Ataxia


SOURCES: MESH OMIM ORPHANET MENDELIAN

More info about FRAGILE X-ASSOCIATED TREMOR/ATAXIA SYNDROME

Juvenile Huntington disease (JHD) is a form of Huntington disease (HD; see this term), characterized by onset of signs and symptoms before 20 years of age.

JUVENILE HUNTINGTON DISEASE Is also known as huntington chorea|jhd|juvenile huntington chorea

Related symptoms:

  • Seizures
  • Ataxia
  • Cognitive impairment
  • Anemia
  • Delayed speech and language development


SOURCES: OMIM ORPHANET MENDELIAN

More info about JUVENILE HUNTINGTON DISEASE

Bilateral striopallidodentate calcinosis (BSPDC, also erroneously called Fahr disease) is characterized by the accumulation of calcium deposits in different brain regions, particularly the basal ganglia and dentate nucleus, and is often associated with neurodegeneration.

BILATERAL STRIOPALLIDODENTATE CALCINOSIS Is also known as cerebrovascular ferrocalcinosis|primary familial brain calcification|ferrocalcinosis, cerebrovascular|pfbc|bspdc|striopallidodentate calcinosis, bilateral|cerebral calcification, nonarteriosclerotic, idiopathic, adult-onset|basal ganglia calcification, id

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Microcephaly
  • Ataxia


SOURCES: ORPHANET OMIM MENDELIAN

More info about BILATERAL STRIOPALLIDODENTATE CALCINOSIS

Xeroderma pigmentosum is an autosomal recessive disorder characterized by sun sensitivity and increased skin sensitivity to UV light, as well as an increased risk of skin cancer associated with a defect in nucleotide excision repair (NER). The XPF form of XP is usually relatively mild compared to other forms. Patients with XPF tend to have later onset of skin cancer. Some patients with XPF may develop neurologic impairment or growth defects, and are then classified as having Cockayne syndrome (summary by Kashiyama et al., 2013).For a general phenotypic description and a discussion of genetic heterogeneity of xeroderma pigmentosa, see XPA (OMIM ), and of Cockayne syndrome, see CSA (OMIM ).

XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP F; XPF Is also known as xp6|xp, group f|xeroderma pigmentosum vi

Related symptoms:

  • Intellectual disability
  • Short stature
  • Hearing impairment
  • Microcephaly
  • Scoliosis


SOURCES: MESH OMIM MENDELIAN

More info about XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP F; XPF

Low match CADASIL

CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a hereditary cerebrovascular disorder characterized by mid-adult onset of recurrent subcortical ischemic stroke and cognitive impairment progressing to dementia in addition to migraines with aura and mood disturbances seen in about a third of patients.

CADASIL Is also known as dementia, hereditary multi-infarct type|cadasil|cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy|casil|hereditary multi-infarct dementia

Related symptoms:

  • Seizures
  • Hearing impairment
  • Ataxia
  • Sensorineural hearing impairment
  • Muscle weakness


SOURCES: OMIM ORPHANET MENDELIAN

More info about CADASIL

Top 5 symptoms//phenotypes associated to Hypertension and Dementia

Symptoms // Phenotype % cases
Mental deterioration Common - Between 50% and 80% cases
Seizures Common - Between 50% and 80% cases
Ataxia Common - Between 50% and 80% cases
Dysarthria Common - Between 50% and 80% cases
Tremor Common - Between 50% and 80% cases

Other less frequent symptoms

Patients with Hypertension and Dementia. may also develop some of the following symptoms:

Common Symptoms - More than 50% cases

Memory impairment

Uncommon Symptoms - Between 30% and 50% cases

Cognitive impairment

Common Symptoms - More than 50% cases

Dysphagia

Uncommon Symptoms - Between 30% and 50% cases

Stroke Gait disturbance Hyperreflexia Depressivity Encephalopathy Pain Cerebellar atrophy Gait ataxia Nystagmus Brain atrophy Slurred speech Apathy Bradykinesia Chorea Urinary incontinence Progressive neurologic deterioration Dysmetria Rigidity Abnormality of the cerebral white matter Headache Behavioral abnormality Delayed speech and language development Hemiparesis Progressive cerebellar ataxia Muscle weakness Confusion Neurodegeneration Abnormal cerebellum morphology Aphasia Abnormality of movement Gliosis Neuronal loss in central nervous system Vertigo Hearing impairment Intellectual disability Personality changes Anxiety Abnormality of extrapyramidal motor function Cerebral ischemia Parkinsonism Spasticity Transient ischemic attack Myocardial infarction Leukoencephalopathy

Rare Symptoms - Less than 30% cases

Developmental regression Facial palsy Myalgia Motor delay Abnormality of eye movement Broad-based gait Visual impairment Clumsiness Intrauterine growth retardation Schizophrenia Pseudobulbar paralysis Stroke-like episode Progressive encephalopathy Emotional lability Microcephaly Mania Paralysis Hemiplegia Psychosis Aggressive behavior Dysdiadochokinesis Obsessive-compulsive behavior Mask-like facies Postural instability Bipolar affective disorder Subcutaneous hemorrhage Subcortical dementia Irritability Cerebral cortical atrophy Migraine Peripheral neuropathy Anemia Ventriculomegaly Global developmental delay Dystonia Amaurosis fugax Attention deficit hyperactivity disorder Hyperactivity Sensorineural hearing impairment Tetraparesis Diffuse leukoencephalopathy Peripheral demyelination Diplopia Urinary bladder sphincter dysfunction Impotence Agitation Hyperkinesis Amyloidosis Astrocytosis Cerebral hemorrhage Intracranial hemorrhage Cerebral calcification Abnormal autonomic nervous system physiology Fever Babinski sign Neurofibrillary tangles Diabetes mellitus Alzheimer disease Coma Fatigue Inability to walk Abnormal pyramidal sign Generalized tonic-clonic seizures Weight loss Myoclonus Pseudohypoparathyroidism Alcoholism Mood swings Perseveration Limb dysmetria Abnormality of nervous system morphology Migraine with aura Focal motor seizures Micrographia Dense calcifications in the cerebellar dentate nucleus Short stature Progressive choreoathetosis Focal dystonia Pill-rolling tremor Calcification of the small brain vessels Orofacial dyskinesia Abnormality of neuronal migration Calcinosis Corneal opacity Paranoia Abnormal involuntary eye movements Neuronal loss in basal ganglia Suicidal ideation Frequent temper tantrums Oral motor hypotonia Scintillating scotoma Hepatomegaly Nonarteritic anterior ischemic optic neuropathy Recurrent subcortical infarcts Thrombocytopenia Abnormality of the liver Neurological speech impairment Abnormal lower motor neuron morphology Dyskinesia Abulia Retinal arteriolar tortuosity Choreoathetosis Focal sensory seizure Muscle stiffness Oral-pharyngeal dysphagia Athetosis Growth delay Basal ganglia calcification Frontotemporal dementia Lewy bodies Scoliosis Optic neuropathy Neoplasm Dilated fourth ventricle Shock Atherosclerosis Verrucae Spastic tetraparesis Recurrent pneumonia Truncal ataxia Abnormality of the skin Tetraplegia Sensory neuropathy Morphological abnormality of the central nervous system Defective DNA repair after ultraviolet radiation damage Cholangiocarcinoma Freckling Seborrheic keratosis Numerous pigmented freckles Nausea Myopathy Vomiting Hypertonia Lower limb muscle weakness Visual loss Elevated serum creatine phosphokinase Pallor EEG abnormality Hypoglycemia Tubular atrophy Cranial nerve paralysis Varicose veins Abnormality of the nervous system Flexion contracture Abnormality of visual evoked potentials Abnormality of the eye Feeding difficulties Impaired pain sensation Renal insufficiency Cerebral atrophy Photophobia Deeply set eye Bulbar palsy Proteinuria Erythema Neoplasm of the skin Scotoma Abnormal electroretinogram Papule Astigmatism Muscle cramps Delayed myelination Prominent nose Microdontia Cutaneous photosensitivity Decreased body weight Cafe-au-lait spot Bone marrow hypocellularity Testicular atrophy Spastic paraparesis Chronic bronchitis Diffuse demyelination of the cerebral white matter Unsteady gait Spastic gait Back pain Urinary urgency Gaze-evoked nystagmus Spastic ataxia Low back pain Arteriosclerosis Diffuse white matter abnormalities Knee pain Pseudobulbar signs Arteriosclerosis of small cerebral arteries Sparse hair Nephropathy Vasculitis Systemic lupus erythematosus Heart murmur Cutis marmorata Visual field defect Atrophic scars Thrombocytosis Acrocyanosis Arteriovenous malformation Peripheral arterial stenosis Ophthalmoplegia Osteoporosis Hemianopia Tachycardia Apraxia Long-tract signs Agnosia Senile plaques Cerebral amyloid angiopathy Cerebellar hemorrhage Recurrent cerebral hemorrhage Tortuous cerebral arteries Constipation Hyperhidrosis Apnea Hallucinations Alopecia Stridor Insomnia Hyperventilation Hypothermia Bulbar signs Dysuria Central apnea Urinary retention Hypersomnia Delirium Snoring Facial paralysis Arterial stenosis Head tremor Falls Abnormality of brainstem morphology Abnormal nerve conduction velocity Impaired distal vibration sensation Diffuse cerebellar atrophy Obsessive-compulsive trait Retrocollis Inertia Impaired tandem gait Arthritis Cough Infertility Generalized-onset seizure Poor fine motor coordination Type II diabetes mellitus Involuntary movements Incoordination Rheumatoid arthritis Akinesia Hypokinesia Muscle fibrillation Bronchitis Cerebellar vermis atrophy Restlessness Upper limb undergrowth Pollakisuria Saccadic smooth pursuit Thromboembolic stroke Horizontal nystagmus Vascular skin abnormality Antiphospholipid antibody positivity Lupus anticoagulant Hyporeflexia Autism Hypothyroidism Proximal muscle weakness Distal sensory impairment Hypotension Intention tremor Limb ataxia Paraparesis Dysesthesia Premature ovarian insufficiency Postural tremor Global brain atrophy Bowel incontinence Abnormality of the thyroid gland Resting tremor Atrophy/Degeneration affecting the brainstem Action tremor Diffuse cerebral atrophy Olivopontocerebellar atrophy Disinhibition Kinetic tremor Subdural hemorrhage


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