Hypertension, and Confusion

Diseases related with Hypertension and Confusion

In the following list you will find some of the most common rare diseases related to Hypertension and Confusion that can help you solving undiagnosed cases.

Top matches:

Corticosteroid-binding globulin deficiency is a rare, genetic, adrenal disease characterized by diminished corticosteroid-binding capacity associated with normal or low plasma corticosteroid-binding globulin concentration and reduced total plasma cortisol levels. Patients typically present chronic pain, fatigue and hypo/hypertension.

CORTICOSTEROID-BINDING GLOBULIN DEFICIENCY Is also known as transcortin deficiency|cbg deficiency

Related symptoms:

  • Pain
  • Hypertension
  • Fatigue
  • Abnormality of metabolism/homeostasis
  • Depressivity


SOURCES: OMIM ORPHANET MENDELIAN

More info about CORTICOSTEROID-BINDING GLOBULIN DEFICIENCY

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a common cause of hyponatremia. The syndrome manifests as an inability to excrete a free water load, with inappropriately concentrated urine and resultant hyponatremia, hypoosmolality, and natriuresis. SIADH occurs in a setting of normal blood volume, without evidence of renal disease or deficiency of thyroxine or cortisol. Although usually transient, SIADH may be chronic; it is often associated with drug use or a lesion in the central nervous system or lung. When the cardinal features of SIADH were defined by Bartter and Schwartz (1967), levels of AVP could not be measured. Subsequently, radioimmunoassays revealed that SIADH is usually associated with measurably elevated serum levels of AVP. Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) is characterized by a clinical picture similar to SIADH, but is associated with undetectable levels of AVP (Feldman et al., 2005).

Related symptoms:

  • Seizures
  • Pain
  • Hypertension
  • Edema
  • Hypoglycemia


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about NEPHROGENIC SYNDROME OF INAPPROPRIATE ANTIDIURESIS; NSIAD

Focal segmental glomerulosclerosis (FSGS) is a pathologic finding in several renal disorders that manifest clinically as proteinuria and progressive decline in renal function. Some patients with FSGS develop the clinical entity called 'nephrotic syndrome' (see NPHS1; {256300}), which includes massive proteinuria, hypoalbuminemia, hyperlipidemia, and edema. However, patients with FSGS may have proteinuria in the nephrotic range without other features of the nephrotic syndrome (summary by D'Agati et al., 2004; Mathis et al., 1998).D'Agati et al. (2011) provided a detailed review of FSGS, emphasizing that the disorder results from defects of the podocyte.Because of confusion in the literature regarding use of the terms 'nephrotic syndrome' and 'focal segmental glomerulosclerosis' (see NOMENCLATURE section), these disorders in OMIM are classified as NPHS or FSGS according to how they were first designated in the literature. Genetic Heterogeneity of Focal Segmental Glomerulosclerosis and Nephrotic SyndromeFocal segmental glomerulosclerosis and nephrotic syndrome are genetically heterogeneous disorders representing a spectrum of hereditary renal diseases. See also FSGS2 (OMIM ), caused by mutation in the TRPC6 gene (OMIM ); FSGS3 (OMIM ), associated with variation in the CD2AP gene (OMIM ); FSGS4 (OMIM ), mapped to chromosome 22q12; FSGS5 (OMIM ), caused by mutation in the INF2 gene (OMIM ); FSGS6 (OMIM ), caused by mutation in the MYO1E gene (OMIM ); FSGS7 (OMIM ), caused by mutation in the PAX2 gene (OMIM ); FSGS8 (OMIM ), caused by mutation in the ANLN gene (OMIM ); and FSGS9 (OMIM ), caused by mutation in the CRB2 gene (OMIM ).See also NPHS1 (OMIM ), caused by mutation in the NPHS1 gene (OMIM ); NPHS2 (OMIM ), caused by mutation in the podocin gene (OMIM ); NPHS3 (OMIM ), caused by mutation in the PLCE1 gene (OMIM ); and NPHS4 (OMIM ), caused by mutation in the WT1 gene (OMIM ).

FOCAL SEGMENTAL GLOMERULOSCLEROSIS 1; FSGS1 Is also known as glomerulosclerosis, focal segmental, 1

Related symptoms:

  • Hearing impairment
  • Pain
  • Anemia
  • Hypertension
  • Edema


SOURCES: OMIM MESH MENDELIAN

More info about FOCAL SEGMENTAL GLOMERULOSCLEROSIS 1; FSGS1

Other less relevant matches:

Medium match PITUITARY APOPLEXY

The sudden loss of blood supply to the PITUITARY GLAND, leading to tissue NECROSIS and loss of function (PANHYPOPITUITARISM). The most common cause is hemorrhage or INFARCTION of a PITUITARY ADENOMA. It can also result from acute hemorrhage into SELLA TURCICA due to HEAD TRAUMA; INTRACRANIAL HYPERTENSION; or other acute effects of central nervous system hemorrhage. Clinical signs include severe HEADACHE; HYPOTENSION; bilateral visual disturbances; UNCONSCIOUSNESS; and COMA.

Related symptoms:

  • Ptosis
  • Hypertension
  • Fever
  • Fatigue
  • Headache


SOURCES: MESH ORPHANET MENDELIAN

More info about PITUITARY APOPLEXY

Fatal familial insomnia (FFI) is a very rare form of prion disease (see this term) characterized by subacute onset of insomnia showing as a reduced overall sleep time, autonomic dysfunction, and motor disturbances.

FATAL FAMILIAL INSOMNIA Is also known as insomnia, fatal familial

Related symptoms:

  • Seizures
  • Ataxia
  • Nystagmus
  • Spasticity
  • Hypertension


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about FATAL FAMILIAL INSOMNIA

Congenital thrombotic thrombocytopenic purpura is the hereditary form of thrombotic thrombocytopenic purpura (TTP; see this term) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and single or multiple organ failure of variable severity.

CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA Is also known as congenital ttp|microangiopathic hemolytic anemia|thrombotic microangiopathy, familial|microangiopathic hemolytic anemia, congenital|congenital adamts-13 deficiency|upshaw factor, deficiency of|uss|thrombotic thrombocytopenic purpura, familial|familial ttp

Related symptoms:

  • Seizures
  • Pain
  • Anemia
  • Hypertension
  • Fever


SOURCES: OMIM ORPHANET MENDELIAN

More info about CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA

DYSTONIA, DOPA-RESPONSIVE; DRD Is also known as dystonia, progressive, with diurnal variation|dystonia 5|segawa syndrome, autosomal dominant|dystonia, dopa-responsive, autosomal dominant|dopa-responsive dystonia, autosomal dominant|dystonia-parkinsonism with diurnal fluctuation|dyt5

Related symptoms:

  • Intellectual disability
  • Hearing impairment
  • Scoliosis
  • Nystagmus
  • Spasticity


SOURCES: ORPHANET OMIM MENDELIAN

More info about DYSTONIA, DOPA-RESPONSIVE; DRD

Acute intermittent porphyria is the most frequent and the most severe form of the acute hepatic porphyrias (see this term). It is characterized by the occurrence of neuro-visceral attacks without cutaneous manifestations.

ACUTE INTERMITTENT PORPHYRIA Is also known as ups deficiency|porphyria, swedish type|pbgd deficiency|porphobilinogen deaminase deficiency|uroporphyrinogen synthase deficiency

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Muscle weakness
  • Pain


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about ACUTE INTERMITTENT PORPHYRIA

Medium match SNEDDON SYNDROME

Sneddon's syndrome (SS) is a rare non-inflammatory thrombotic vasculopathy characterized by the combination of cerebrovascular disease with livedo racemosa.

SNEDDON SYNDROME Is also known as livedo reticularis-cerebrovascular accident syndrome|livedo racemosa-cerebrovascular accident syndrome|livedo reticularis and cerebrovascular accidents|ehrmann-sneddon syndrome

Related symptoms:

  • Seizures
  • Muscle weakness
  • Pain
  • Visual impairment
  • Motor delay


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about SNEDDON SYNDROME

Hereditary coproporphyria is a form of acute hepatic porphyria (see this term) characterized by the occurrence of neuro-visceral attacks and, more rarely, by the presence of cutaneous lesions.

HEREDITARY COPROPORPHYRIA Is also known as cpox deficiency|cpx deficiency|coproporphyrinogen oxidase deficiency|cpo deficiency

Related symptoms:

  • Seizures
  • Muscle weakness
  • Pain
  • Anemia
  • Hypertension


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about HEREDITARY COPROPORPHYRIA

Top 5 symptoms//phenotypes associated to Hypertension and Confusion

Symptoms // Phenotype % cases
Pain Common - Between 50% and 80% cases
Seizures Common - Between 50% and 80% cases
Fatigue Uncommon - Between 30% and 50% cases
Depressivity Uncommon - Between 30% and 50% cases
Coma Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Hypertension and Confusion. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Anxiety Nausea Nausea and vomiting Anemia Paralysis Hyponatremia Tremor Behavioral abnormality Constipation Vomiting Insomnia Fever Headache Tachycardia Hypotension Delirium Renal insufficiency Myalgia Diarrhea Arrhythmia Abdominal pain Hallucinations Irritability Muscle weakness

Rare Symptoms - Less than 30% cases

Gait ataxia Red urine Weight loss Dysarthria Hyperhidrosis Mental deterioration Acute episodes of neuropathic symptoms Encephalopathy Respiratory paralysis Memory impairment Urinary retention Ileus Arthralgia Motor delay Intellectual disability Prolonged neonatal jaundice Personality changes Hemiparesis Hemolytic anemia Jaundice Hepatosplenomegaly Apathy Nystagmus Paresthesia Nephropathy Dysuria Psychosis Cutaneous photosensitivity Aphasia Agitation Spasticity Dementia Stage 5 chronic kidney disease Increased circulating cortisol level Proteinuria Hematuria Hyperlipidemia Lethargy Hypoglycemia Edema Microscopic hematuria Pallor Diplopia Cranial nerve paralysis Impotence Hearing impairment Abnormality of metabolism/homeostasis Lower limb hyperreflexia Dysphonia Fixed facial expression Abnormality of the substantia nigra Decreased CSF homovanillic acid Visual hallucinations Obsessive-compulsive behavior Paresis of extensor muscles of the big toe Global developmental delay Rheumatoid arthritis Torticollis Cerebral palsy Transient hyperphenylalaninemia Intellectual disability, mild Fragile skin Orthostatic hypotension Hypermelanotic macule Horizontal nystagmus Thin skin Hypertrichosis Involuntary movements Auditory hallucinations Paranoia Resting tremor Brisk reflexes Hyperactive deep tendon reflexes Impaired vibration sensation in the lower limbs Compensated hemolytic anemia Limb dystonia Generalized dystonia Focal dystonia Gaze-evoked nystagmus Upper motor neuron dysfunction Torsion dystonia Congenital hemolytic anemia Spastic diplegia Parkinsonism with favorable response to dopaminergic medication Postural tremor Abnormal blistering of the skin Writer's cramp Axial dystonia Infantile encephalopathy Obsessive-compulsive trait Progressive flexion contractures Oromandibular dystonia Thrombocytosis Metabolic acidosis Stroke Bradykinesia Cerebral ischemia Facial paralysis Visual impairment Peripheral arterial stenosis Arteriovenous malformation Acrocyanosis Transient ischemic attack Facial palsy Developmental regression Vertigo Arterial stenosis Chorea Migraine Myocardial infarction Vasculitis Systemic lupus erythematosus Hemiplegia Intracranial hemorrhage Heart murmur Cutis marmorata Visual field defect Hemianopia Elevated urinary delta-aminolevulinic acid Carcinoma Paraparesis Atrophic scars Pruritus Elevated hepatic transaminase Abdominal distention Urinary incontinence Acidosis Areflexia Splenomegaly Hepatomegaly Anorexia Hepatocellular carcinoma Thromboembolic stroke Peripheral neuropathy Lupus anticoagulant Diaphragmatic paralysis Abnormal urinary color Antiphospholipid antibody positivity Psychotic episodes Hypertensive crisis Vascular skin abnormality Amaurosis fugax Paralytic ileus Abnormality of extrapyramidal motor function Acute kidney injury Parkinsonism Mydriasis Growth hormone excess Oligomenorrhea Prolactin excess Pituitary adenoma Excessive daytime somnolence Pituitary hypothyroidism Adrenocorticotropic hormone deficiency Central diabetes insipidus Normochromic anemia Galactorrhea Abnormality of the cerebrospinal fluid Prolactin deficiency Blurred vision Trigeminal neuralgia Bitemporal hemianopia Abnormal kinetic perimetry test Thunderclap headache Abnormal caudate nucleus morphology Abnormal static automated perimetry test Ataxia Dysphagia Cerebellar atrophy Myoclonus Apnea Hypopituitarism Hypergonadotropic hypogonadism Inability to walk Inappropriate antidiuretic hormone secretion Hepatic steatosis Chronic fatigue Chronic pain Increased muscle fatiguability Asthenia Generalized-onset seizure Muscle fibrillation Decreased circulating renin level Hypernatriuria Elevated systolic blood pressure Decreased serum creatinine Ascites Growth hormone deficiency Nephrotic syndrome Chronic kidney disease Hypoalbuminemia Glomerulosclerosis Focal segmental glomerulosclerosis Ocular pain Microalbuminuria Congenital nephrotic syndrome Ptosis Reduced visual acuity Photophobia Generalized tonic-clonic seizures Neurodegeneration Abnormal cerebellum morphology Hypertonia Abnormal renal physiology Hemolytic-uremic syndrome Neonatal hyperbilirubinemia Bloody diarrhea Increased blood urea nitrogen Microangiopathic hemolytic anemia Schistocytosis Scoliosis Hyperreflexia Gait disturbance Talipes equinovarus Dystonia Elevated serum creatinine Babinski sign Pes cavus Hypothyroidism Difficulty walking Rigidity Hyperlordosis Abnormal pyramidal sign Spastic paraplegia Abnormality of movement Paraplegia Sleep disturbance Preeclampsia Reticulocytosis Gliosis Astrocytosis Neuronal loss in central nervous system Progressive neurologic deterioration Abnormal autonomic nervous system physiology Hyperkinesis Slurred speech Stridor Hyperventilation Urinary bladder sphincter dysfunction Hypothermia Bulbar signs Central apnea Hypersomnia Autoimmune thrombocytopenia Snoring Respiratory distress Thrombocytopenia Abnormality of the kidney Skin rash Abnormal bleeding Increased serum lactate Hyperbilirubinemia Purpura Glomerulonephritis Hyperkalemia Abdominal colic


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