Hyperreflexia, and Dysphagia

Diseases related with Hyperreflexia and Dysphagia

In the following list you will find some of the most common rare diseases related to Hyperreflexia and Dysphagia that can help you solving undiagnosed cases.

Top matches:

Autosomal dominant striatal degeneration (ADSD) is an adult-onset movement disorder characterized by bradykinesia, dysarthria and muscle rigidity.

AUTOSOMAL DOMINANT STRIATAL NEURODEGENERATION Is also known as adsd

Related symptoms:

  • Dysarthria
  • Tremor
  • Gait disturbance
  • Dysphagia
  • Rigidity


SOURCES: OMIM ORPHANET MENDELIAN

More info about AUTOSOMAL DOMINANT STRIATAL NEURODEGENERATION

Related symptoms:

  • Spasticity
  • Cognitive impairment
  • Hyperreflexia
  • Dysarthria
  • Dysphagia


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS, SUSCEPTIBILITY TO, 24; ALS24

CHILDHOOD-ONSET BASAL GANGLIA DEGENERATION SYNDROME Is also known as lenk-ploski syndrome

Related symptoms:

  • Delayed speech and language development
  • Hyperreflexia
  • Dysphagia
  • Hypertonia
  • Dystonia


SOURCES: ORPHANET OMIM MENDELIAN

More info about CHILDHOOD-ONSET BASAL GANGLIA DEGENERATION SYNDROME

Other less relevant matches:

Primary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production.

PRIMARY LATERAL SCLEROSIS Is also known as pls, adult|adult-onset primary lateral sclerosis|adult-onset pls|pls|plsa

Related symptoms:

  • Muscle weakness
  • Spasticity
  • Peripheral neuropathy
  • Hyperreflexia
  • Dysarthria


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about PRIMARY LATERAL SCLEROSIS

Spinocerebellar ataxia type 6 (SCA6) is the most common subtype of autosomal dominant cerebellar ataxia type III (ADCA type III; see this term) characterized by late-onset and slowly progressive gait ataxia and other cerebellar signs such as impaired muscle coordination and nystagmus.

SPINOCEREBELLAR ATAXIA TYPE 6 Is also known as sca6

Related symptoms:

  • Nystagmus
  • Hyperreflexia
  • Dysarthria
  • Dysphagia
  • Dystonia


SOURCES: ORPHANET MENDELIAN

More info about SPINOCEREBELLAR ATAXIA TYPE 6

SPINOCEREBELLAR ATAXIA 19; SCA19 Is also known as sca22|spinocerebellar ataxia 22

Related symptoms:

  • Seizures
  • Ataxia
  • Nystagmus
  • Cognitive impairment
  • Hyperreflexia


SOURCES: OMIM MENDELIAN

More info about SPINOCEREBELLAR ATAXIA 19; SCA19

Spinocerebellar ataxia type 28 (SCA28) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by juvenile onset, slowly progressive cerebellar ataxia due to Purkinje cell degeneration.

SPINOCEREBELLAR ATAXIA TYPE 28 Is also known as sca28

Related symptoms:

  • Ataxia
  • Nystagmus
  • Spasticity
  • Ptosis
  • Cognitive impairment


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about SPINOCEREBELLAR ATAXIA TYPE 28

Medium match DYSTONIA 16

Dystonia 16 (DYT16) is a very rare and newly discovered movement disorder which is characterized by early-onset progressive limb dystonia, laryngeal and oromandibular dystonia, and parkinsonism.

DYSTONIA 16 Is also known as dyt16|early-onset dystonia parkinsonism

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Pain
  • Cognitive impairment
  • Delayed speech and language development


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about DYSTONIA 16

Related symptoms:

  • Ataxia
  • Nystagmus
  • Cognitive impairment
  • Hyperreflexia
  • Dysarthria


SOURCES: OMIM MENDELIAN

More info about SPINOCEREBELLAR ATAXIA 14; SCA14

Hereditary spastic ataxia comprises a heterogeneous group of progressive neurodegenerative disorders characterized by lower-limb spasticity and generalized ataxia with dysarthria, impaired ocular movements, and gait disturbance. Spastic ataxia-1 (SPAX1) is an autosomal dominant form of the disorder with linkage to chromosome 12p13 (summary by Meijer et al., 2002). Genetic Heterogeneity of Spastic AtaxiaSee also SPAX2 (OMIM ), caused by mutation in the KIF1C gene (OMIM ) on chromosome 17p13; SPAX3 (OMIM ), caused by rearrangements of the MARS2 gene (OMIM ) on chromosome 2q33; SPAX4 (OMIM ), caused by mutation in the MTPAP gene (OMIM ) on chromosome 10p11; SPAX5 (OMIM ), caused by mutation in the AFG3L2 gene (OMIM ) on chromosome 18p11; SPAX6 (OMIM ), caused by mutation in the SACS gene (OMIM ) on chromosome 13q12; SPAX7 (OMIM ); and SPAX8 (OMIM ), caused by mutation in the NKX6-2 gene (OMIM ) on chromosome 8q21.

Related symptoms:

  • Ataxia
  • Spasticity
  • Ptosis
  • Hyperreflexia
  • Dysarthria


SOURCES: OMIM MENDELIAN

More info about SPASTIC ATAXIA 1, AUTOSOMAL DOMINANT; SPAX1

Top 5 symptoms//phenotypes associated to Hyperreflexia and Dysphagia

Symptoms // Phenotype % cases
Dysarthria Very Common - Between 80% and 100% cases
Dystonia Common - Between 50% and 80% cases
Gait disturbance Uncommon - Between 30% and 50% cases
Cognitive impairment Uncommon - Between 30% and 50% cases
Nystagmus Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Hyperreflexia and Dysphagia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Spasticity Tremor Ataxia Gait ataxia Rigidity Progressive cerebellar ataxia Cerebellar atrophy Babinski sign Unsteady gait Hypertonia Parkinsonism Memory impairment Abnormality of eye movement

Rare Symptoms - Less than 30% cases

Spastic gait Slow saccadic eye movements Gaze-evoked horizontal nystagmus Head tremor Limb dystonia Myoclonus Limb ataxia Postural tremor Akinesia Ptosis Depressivity Impaired vibratory sensation Amyotrophic lateral sclerosis Abnormality of movement Bradykinesia Delayed speech and language development Lower limb hyperreflexia Absent speech Tetraparesis Facial myokymia Pain Global developmental delay Intellectual disability Dysmetric saccades Kinetic tremor Impaired vibration sensation at ankles Spastic paraplegia Skeletal muscle atrophy Pes cavus Paraplegia Neuronal loss in central nervous system Supranuclear gaze palsy Gaze-evoked nystagmus Ophthalmoparesis Spastic ataxia Ophthalmoplegia Motor delay Abnormal pyramidal sign Chorea Orofacial dyskinesia Abnormal cerebellum morphology Dysmetria Attention deficit hyperactivity disorder Mental deterioration Retrocollis Limb pain Facial grimacing Focal dystonia Laryngeal dystonia Morphological abnormality of the pyramidal tract Scanning speech Myokymia Generalized dystonia Language impairment Dysphonia Ischemic stroke Torticollis Involuntary movements Dyskinesia Stroke Lower limb pain Bradyopsia Behavioral abnormality Elevated serum creatine phosphokinase Muscle weakness Craniofacial dystonia Loss of ability to walk Excessive salivation Steppage gait Drooling Frequent falls Falls Developmental regression Abnormal lower motor neuron morphology Confusion Bulbar signs Respiratory insufficiency Symmetric lesions of the basal ganglia Degeneration of the striatum Abnormality of the basal ganglia Hyperactive deep tendon reflexes Hypokinesia Dysdiadochokinesis Slurred speech Hyperkinesis Peripheral neuropathy Peripheral axonal neuropathy Intermittent microsaccadic pursuits Abnormality of vision Cogwheel rigidity Urinary urgency Horizontal nystagmus Truncal ataxia Hyporeflexia Seizures Choking episodes Vertical nystagmus Blepharospasm Incoordination Diplopia Clumsiness Intention tremor Postural instability Abnormal nerve conduction velocity Abnormal upper motor neuron morphology Degeneration of the lateral corticospinal tracts Spastic dysarthria Spastic tetraparesis Spastic paraparesis Paraparesis Muscle stiffness Leg muscle stiffness


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