Hyperreflexia, and Bradykinesia

Diseases related with Hyperreflexia and Bradykinesia

In the following list you will find some of the most common rare diseases related to Hyperreflexia and Bradykinesia that can help you solving undiagnosed cases.


Top matches:

High match PARKINSON DISEASE 22, AUTOSOMAL DOMINANT; PARK22


Related symptoms:

  • Hyperreflexia
  • Tremor
  • Gait disturbance
  • Depressivity
  • Rigidity


SOURCES: OMIM MENDELIAN

More info about PARKINSON DISEASE 22, AUTOSOMAL DOMINANT; PARK22

High match AUTOSOMAL DOMINANT STRIATAL NEURODEGENERATION


Autosomal dominant striatal degeneration (ADSD) is an adult-onset movement disorder characterized by bradykinesia, dysarthria and muscle rigidity.

AUTOSOMAL DOMINANT STRIATAL NEURODEGENERATION Is also known as adsd

Related symptoms:

  • Dysarthria
  • Tremor
  • Gait disturbance
  • Dysphagia
  • Rigidity


SOURCES: OMIM ORPHANET MENDELIAN

More info about AUTOSOMAL DOMINANT STRIATAL NEURODEGENERATION

High match SPINOCEREBELLAR ATAXIA TYPE 12


Spinocerebellar ataxia type 12 (SCA12) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by the presence of action tremor associated with relatively mild cerebellar ataxia. Associated pyramidal and extrapyramidal signs and dementia have been reported.

SPINOCEREBELLAR ATAXIA TYPE 12 Is also known as sca12

Related symptoms:

  • Ataxia
  • Cognitive impairment
  • Hyperreflexia
  • Gait disturbance
  • Cerebellar atrophy


SOURCES: ORPHANET MENDELIAN

More info about SPINOCEREBELLAR ATAXIA TYPE 12

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Other less relevant matches:

Medium match X-LINKED PARKINSONISM-SPASTICITY SYNDROME


X-linked parkinsonism-spasticity syndrome is a rare genetic neurological disorder characterized by parkinsonian features (including resting or action tremor, cogwheel rigidity, hypomimia and bradykinesia) associated with variably penetrant spasticity, hyperactive deep tendon reflexes and Babinski sign.

X-LINKED PARKINSONISM-SPASTICITY SYNDROME Is also known as xpds

Related symptoms:

  • Seizures
  • Spasticity
  • Hyperreflexia
  • Tremor
  • Babinski sign


SOURCES: ORPHANET OMIM MENDELIAN

More info about X-LINKED PARKINSONISM-SPASTICITY SYNDROME

Medium match PARKINSON-DEMENTIA SYNDROME


Related symptoms:

  • Hyperreflexia
  • Dysarthria
  • Tremor
  • Dementia
  • Kyphoscoliosis


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about PARKINSON-DEMENTIA SYNDROME

Medium match SPINOCEREBELLAR ATAXIA TYPE 20


Spinocerebellar ataxia type 20 (SCA20) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I; see this term). It is characterized by cerebellar dysarthria as the initial typical manifestation.

SPINOCEREBELLAR ATAXIA TYPE 20 Is also known as sca20

Related symptoms:

  • Ataxia
  • Hyperreflexia
  • Dysarthria
  • Cerebellar atrophy
  • Gait ataxia


SOURCES: ORPHANET MENDELIAN

More info about SPINOCEREBELLAR ATAXIA TYPE 20

Medium match PARKINSON DISEASE 19A, JUVENILE-ONSET; PARK19A


Parkinson disease-19A is an autosomal recessive neurodegenerative disorder characterized by onset of parkinsonism in the first or second decade. Some patients may have additional neurologic features, including mental retardation and seizures (summary by Edvardson et al., 2012 and Koroglu et al., 2013).Parkinson disease-19B is an autosomal recessive neurodegenerative disorder with onset of parkinsonism between the third and fifth decades. It is slowly progressive, shows features similar to classic late-onset Parkinson disease (PD), and has a beneficial response to dopaminergic therapy (Olgiati et al., 2016).For a phenotypic description and a discussion of genetic heterogeneity of Parkinson disease, see PD (OMIM ).

PARKINSON DISEASE 19A, JUVENILE-ONSET; PARK19A Is also known as park19, formerly

Related symptoms:

  • Intellectual disability
  • Seizures
  • Spasticity
  • Cognitive impairment
  • Hyperreflexia


SOURCES: OMIM MENDELIAN

More info about PARKINSON DISEASE 19A, JUVENILE-ONSET; PARK19A

Medium match PARKINSON DISEASE 6, AUTOSOMAL RECESSIVE EARLY-ONSET; PARK6


PARKINSON DISEASE 6, AUTOSOMAL RECESSIVE EARLY-ONSET; PARK6 Is also known as parkinson disease 6, early-onset|park6

Related symptoms:

  • Pain
  • Cognitive impairment
  • Hyperreflexia
  • Tremor
  • Behavioral abnormality


SOURCES: OMIM MESH MENDELIAN

More info about PARKINSON DISEASE 6, AUTOSOMAL RECESSIVE EARLY-ONSET; PARK6

Medium match DYSTONIA 16


Dystonia 16 (DYT16) is a very rare and newly discovered movement disorder which is characterized by early-onset progressive limb dystonia, laryngeal and oromandibular dystonia, and parkinsonism.

DYSTONIA 16 Is also known as dyt16|early-onset dystonia parkinsonism

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Pain
  • Cognitive impairment
  • Delayed speech and language development


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about DYSTONIA 16

Medium match PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE; PARK2


PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE; PARK2 Is also known as pdj|parkinson disease, juvenile, autosomal recessive|parkinsonism, early-onset, with diurnal fluctuation|epdf

Related symptoms:

  • Neoplasm
  • Peripheral neuropathy
  • Hyperreflexia
  • Tremor
  • Gait disturbance


SOURCES: OMIM MENDELIAN

More info about PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE; PARK2

Top 5 symptoms//phenotypes associated to Hyperreflexia and Bradykinesia

Symptoms // Phenotype % cases
Tremor Common - Between 50% and 80% cases
Rigidity Common - Between 50% and 80% cases
Parkinsonism Common - Between 50% and 80% cases
Gait disturbance Uncommon - Between 30% and 50% cases
Dyskinesia Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Hyperreflexia and Bradykinesia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Dysarthria Abnormal pyramidal sign Cognitive impairment Resting tremor Postural instability Dementia Dystonia Akinesia Alzheimer disease Neuronal loss in central nervous system Lewy bodies

Rare Symptoms - Less than 30% cases


Cogwheel rigidity Spasticity Laryngeal dystonia Neurofibrillary tangles Morphological abnormality of the pyramidal tract Dysphonia Tremor by anatomical site Intellectual disability Psychosis Hypomimic face Pain Gliosis Seizures Senile plaques Postural tremor Behavioral abnormality Dysphagia Kinetic tremor Depressivity Hypokinesia Hyperactive deep tendon reflexes Cerebellar atrophy Ataxia Abnormality of movement Abnormal cerebellum morphology Unsteady gait Intention tremor Global developmental delay Parkinsonism with favorable response to dopaminergic medication Orthostatic hypotension Urinary urgency Abnormal autonomic nervous system physiology Hypotension Anxiety Impaired vibratory sensation Sensory axonal neuropathy Anarthria Hypometric saccades Shuffling gait Visual hallucinations Olivopontocerebellar atrophy Global brain atrophy Delayed speech and language development Respiratory failure Diabetes mellitus Lower limb pain Peripheral neuropathy Neoplasm Retrocollis Limb pain Facial grimacing Peripheral axonal neuropathy Orofacial dyskinesia Stroke Generalized dystonia Limb dystonia Language impairment Ischemic stroke Hallucinations Torticollis Involuntary movements Motor delay Intellectual disability, moderate Hyperkinesis Ankle clonus Abnormality of eye movement Mental deterioration Kyphoscoliosis Dilated third ventricle Scissor gait Dilation of lateral ventricles Diffuse cerebral atrophy Mask-like facies Ophthalmoparesis Spastic paraparesis Paraparesis Cerebral atrophy Babinski sign Sensorimotor neuropathy Limb dysmetria Poor fine motor coordination Falls Symmetric lesions of the basal ganglia Generalized-onset seizure Hypermetric saccades Brain atrophy Inability to walk Action tremor Encephalopathy Slurred speech Dysdiadochokinesis Isometric tremor Upper limb postural tremor Degeneration of the striatum Downbeat nystagmus Lower limb hyperreflexia Gaze-evoked nystagmus Cerebral calcification Vertigo Gait ataxia Inappropriate behavior Abnormality of the basal ganglia Substantia nigra gliosis



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