Hepatomegaly, and Abdominal pain
Diseases related with Hepatomegaly and Abdominal pain
In the following list you will find some of the most common rare diseases related to Hepatomegaly and Abdominal pain that can help you solving undiagnosed cases.
High match DUBIN-JOHNSON SYNDROME
Dubin-Johnson syndrome (DJS) is a benign, inherited liver disorder characterized clinically by chronic, predominantly conjugated, hyperbilirubinemia and histopathologically by black-brown pigment deposition in parenchymal liver cells.
DUBIN-JOHNSON SYNDROME Is also known as hyperbilirubinemia ii|hblrdj|hyperbilirubinemia, dubin-johnson type|hyperbilirubinemia type 2|dubin-sprinz disease|sprinz-nelson syndromeRelated symptoms:
- Abdominal pain
More info about DUBIN-JOHNSON SYNDROME
High match HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR
The Rotor type of hyperbilirubinemia is an autosomal recessive form of primary conjugated hyperbilirubinemia. It is similar to Dubin-Johnson syndrome (DJS ) in that affected individuals develop mild jaundice not associated with hemolysis shortly after birth or in childhood. However, Rotor syndrome can be distinguished from DJS by a lack of hepatocyte pigment deposits, delayed plasma clearance of the unconjugated anionic dye bromsulfthalein, poor hepatic visualization on certain radiographic imaging studies, and prominent urinary excretion of coproporphyrin I (summary by van de Steeg et al., 2012).
HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR Is also known as rotor syndromeRelated symptoms:
- Abnormality of the skeletal system
- Abdominal pain
More info about HYPERBILIRUBINEMIA, ROTOR TYPE; HBLRR
High match CAROLI DISEASE
Other less relevant matches:
High match HEPATITIS B VIRUS, SUSCEPTIBILITY TO
HBV is a DNA virus that enters the liver via the bloodstream, and replication occurs only in liver tissue. Transmission occurs by percutaneous or mucosal exposure to infected blood or other body fluids. Approximately one third of all cases of cirrhosis and half of all cases of hepatocellular carcinoma (HCC ) can be attributed to chronic HBV infection. Worldwide, 2 billion people have been infected with HBV, 360 million have chronic infection, and 600,000 die each year from HBV-related liver disease or HCC. However, there is marked geographic variability in HBV prevalence, with chronic infection affecting less than 2% of the populations of North America and western and northern Europe; between 2 and 7% of the populations of eastern and central Europe, the Amazon basin, the Middle East, and the Indian subcontinent; and more than 8% of the populations of Asia, sub-Saharan Africa, and the Pacific (Seeff and Hoofnagle, 2006; Shepard et al., 2006).
HEPATITIS B VIRUS, SUSCEPTIBILITY TO Is also known as hbv, susceptibility toRelated symptoms:
More info about HEPATITIS B VIRUS, SUSCEPTIBILITY TO
High match HYPERLIPOPROTEINEMIA, TYPE ID
High match ISOLATED POLYCYSTIC LIVER DISEASE
Isolated polycystic liver disease (PCLD) is a genetic disorder characterized by the appearance of numerous cysts spread throughout the liver and that in most cases is described as autosomal dominant polycystic liver disease (ADPCLD).
ISOLATED POLYCYSTIC LIVER DISEASE Is also known as pcld|autosomal dominant polycystic liver disease|adpcldRelated symptoms:
- Respiratory insufficiency
- Abdominal pain
- Gastroesophageal reflux
More info about ISOLATED POLYCYSTIC LIVER DISEASE
High match DESMOPLASTIC SMALL ROUND CELL TUMOR
Desmoplastic small round cell tumor (DSRCT) is an aggressive soft tissue cancer that typically arises in serous lined surfaces of the abdominal or pelvic peritoneum, and spreads to the omentum, lymph nodes and hematogenously disseminates especially to the liver. Extraserous primary location has been reported in exceptional cases.
DESMOPLASTIC SMALL ROUND CELL TUMOR Is also known as dsrctRelated symptoms:
More info about DESMOPLASTIC SMALL ROUND CELL TUMOR
High match FAMILIAL APOLIPOPROTEIN C-II DEFICIENCY
FAMILIAL APOLIPOPROTEIN C-II DEFICIENCY Is also known as apoc2 deficiency|hyperlipoproteinemia, type ib|familial apoc-ii deficiency|c-ii anapolipoproteinemiaRelated symptoms:
- Global developmental delay
More info about FAMILIAL APOLIPOPROTEIN C-II DEFICIENCY
High match SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS
Systemic-onset juvenile idiopathic arthritis is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio.
SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS Is also known as systemic-onset jia|systemic juvenile rheumatoid arthritis|still disease|systemic polyarthritisRelated symptoms:
- Visual impairment
- Visual loss
More info about SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS
High match AA AMYLOIDOSIS
Secondary amyloidosis is a form of amyloidosis (see this term), that complicates chronic inflammatory disorders (mainly rheumatoid arthritis, see this term) and is characterized by the aggregation and deposition of amyloid fibrils composed of serum amyloid A protein, an acute phase reactant. Although spleen, suprarenal gland, liver and gut are frequent sites of amyloid deposition, the clinical picture is dominated by renal involvement.
AA AMYLOIDOSIS Is also known as secondary amyloidosis|inflammatory amyloidosis|reactive amyloidosisRelated symptoms:
- Abnormal heart morphology
- Abdominal pain
More info about AA AMYLOIDOSIS
Top 5 symptoms//phenotypes associated to Hepatomegaly and Abdominal pain
|Symptoms // Phenotype||% cases|
|Pain||Common - Between 50% and 80% cases|
|Fever||Uncommon - Between 30% and 50% cases|
|Splenomegaly||Uncommon - Between 30% and 50% cases|
|Hepatosplenomegaly||Uncommon - Between 30% and 50% cases|
|Abnormality of the kidney||Uncommon - Between 30% and 50% cases|
Other less frequent symptoms
Patients with Hepatomegaly and Abdominal pain. may also develop some of the following symptoms:
Uncommon Symptoms - Between 30% and 50% casesVomiting Ascites Jaundice Abnormality of the liver Fatigue
Rare Symptoms - Less than 30% casesHyperlipoproteinemia Abdominal distention Pancreatitis Polycystic kidney dysplasia Abnormality of the cardiovascular system Gastrointestinal hemorrhage Eruptive xanthomas Lipemia retinalis Nausea Epigastric pain Abnormality of the nervous system Hypertriglyceridemia Lymphadenopathy Cholestasis Abnormality of the gastric mucosa Hyperbilirubinemia Abnormality of coagulation Conjugated hyperbilirubinemia Biliary tract abnormality Dark urine Abnormal urinary color Increased circulating chylomicron concentration Dilatation Renal cyst Arthralgia Episodic abdominal pain Chronic pancreatitis Joint swelling Lethargy Uveitis Global developmental delay Visual impairment Visual loss Macrocephaly Encephalopathy Pericarditis Elevated erythrocyte sedimentation rate Rheumatoid arthritis Pleural effusion Hypercholesterolemia Skin rash Cerebral atrophy Autoimmunity Arthritis Myalgia Falls Malabsorption Juvenile rheumatoid arthritis Atrioventricular block Cardiac amyloidosis Abnormal cardiac ventricle morphology Renal amyloidosis Abnormal oral mucosa morphology Abnormal echocardiogram Abnormal renal physiology Enlarged kidney Acute kidney injury Amyloidosis Malnutrition Adrenal insufficiency Chronic kidney disease Elevated C-reactive protein level Venous thrombosis Ventricular tachycardia Chronic diarrhea Nephrotic syndrome Hypotension Nephropathy Abdominal mass Proteinuria Hypothyroidism Abnormal heart morphology Serositis Anterior uveitis Gastrointestinal obstruction Increased total bilirubin Abnormality of the peritoneum Carcinoma Failure to thrive Fulminant hepatitis Acute hepatitis Membranous nephropathy Chronic infection Membranoproliferative glomerulonephritis Hepatocellular carcinoma Glomerulonephritis Hepatitis Cirrhosis Cholangiocarcinoma Colitis Liver abscess Cholangitis Esophageal varix Episodic fever Portal hypertension Pruritus Hypertension Abnormality of skin pigmentation Abnormality of the skeletal system Intermittent jaundice Hyperlipidemia Acute pancreatitis Testicular neoplasm Constipation Neoplasm of the central nervous system Mediastinal lymphadenopathy Ileus Neoplasm of the pancreas Neoplasm of the lung Ovarian neoplasm Sarcoma Cachexia Nausea and vomiting Weight loss Anemia Respiratory insufficiency Neoplasm Polycystic liver disease Hepatic cysts Abnormality of the pancreas Abnormality of the respiratory system Multiple renal cysts Cerebral hemorrhage Elevated alkaline phosphatase Back pain Feeding difficulties in infancy Gastroesophageal reflux Hepatic amyloidosis
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