Fever, and Palmoplantar keratoderma

Diseases related with Fever and Palmoplantar keratoderma

In the following list you will find some of the most common rare diseases related to Fever and Palmoplantar keratoderma that can help you solving undiagnosed cases.

Top matches:

Medium match SÉZARY SYNDROME

Sézary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma characterized by a triad of erythroderma, lymphadenopathy and circulating atypical lymphocytes (Sézary cells).

SÉZARY SYNDROME Is also known as sÉzary lymphoma

Related symptoms:

  • Neoplasm
  • Abnormal facial shape
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


SOURCES: MESH ORPHANET MENDELIAN

More info about SÉZARY SYNDROME

Naegeli-Franceschetti-Jadassohn (NFJ) syndrome is a rare ectodermal dysplasia that affects the skin, sweat glands, nails, and teeth.

NAEGELI-FRANCESCHETTI-JADASSOHN SYNDROME Is also known as nfj syndrome|naegeli syndrome

Related symptoms:

  • Hyperhidrosis
  • Hyperkeratosis
  • Carious teeth
  • Palmoplantar keratoderma
  • Ectodermal dysplasia


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about NAEGELI-FRANCESCHETTI-JADASSOHN SYNDROME

Ectodermal dysplasia-syndactyly syndrome is a rare, genetic ectodermal dysplasia syndrome characterized by sparse to absent scalp hair, eyebrows, and eyelashes (with pili torti when present), widely spaced, conical-shaped teeth with peg-shaped, conical crowns and enamel hypoplasia and palmoplantar hyperkeratosis, associated with partial cutaneous syndactyly in hands and feet.

ECTODERMAL DYSPLASIA-SYNDACTYLY SYNDROME Is also known as edss|edss1

Related symptoms:

  • Cognitive impairment
  • Syndactyly
  • Alopecia
  • Hyperhidrosis
  • Hyperkeratosis


SOURCES: ORPHANET OMIM MENDELIAN

More info about ECTODERMAL DYSPLASIA-SYNDACTYLY SYNDROME

Other less relevant matches:

Epidermolytic ichthyosis (EI) is a rare keratinopathic ichthyosis (KPI; see this term), that is characterized by a blistering phenotype at birth which progressively becomes hyperkeratotic.

AUTOSOMAL DOMINANT EPIDERMOLYTIC ICHTHYOSIS Is also known as bullous congenital ichthyosiform erythroderma of brock|epidermolytic ichthyosis|bie|bullous congenital ichthyosiform erythroderma|ehk|bullous erythroderma ichthyosiformis congenita of brocq|bcie|bullous ichthyosiform erythroderma|ichthyosis hystrix brocq

Related symptoms:

  • Growth delay
  • Hyperhidrosis
  • Hyperkeratosis
  • Weight loss
  • Erythema


SOURCES: OMIM ORPHANET MENDELIAN

More info about AUTOSOMAL DOMINANT EPIDERMOLYTIC ICHTHYOSIS

ANKYLOBLEPHARON-ECTODERMAL DEFECTS-CLEFT LIP/PALATE Is also known as hay-wells syndrome|aec syndrome

Related symptoms:

  • Short stature
  • Hearing impairment
  • Failure to thrive
  • Cleft palate
  • Pain


SOURCES: OMIM MESH MENDELIAN

More info about ANKYLOBLEPHARON-ECTODERMAL DEFECTS-CLEFT LIP/PALATE

Ichthyosis follicularis - alopecia - photophobia (IFAP) is a rare genetic disorder characterized by the triad of ichthyosis follicularis, alopecia, and photophobia from birth.

ICHTHYOSIS FOLLICULARIS-ALOPECIA-PHOTOPHOBIA SYNDROME Is also known as ichthyosis follicularis-atrichia-photophobia syndrome|ifap syndrome|ichthyosis follicularis, atrichia, and photophobia with or without brain anomalies, retardation, ectodermal dysplasia, skeletal malformations, hirschsprung disease, ear/eye anomalies, cle

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Hearing impairment


SOURCES: ORPHANET OMIM MENDELIAN

More info about ICHTHYOSIS FOLLICULARIS-ALOPECIA-PHOTOPHOBIA SYNDROME

Epidermolysis bullosa simplex (EBS) is a clinically and genetically heterogeneous skin disorder characterized by recurrent blistering of the skin following minor physical trauma as a result of cytolysis within basal epidermal cells. Most forms show autosomal dominant inheritance. The 3 main types include the generalized Koebner form, the more severe generalized Dowling-Meara form (OMIM ), and the localized, mild Weber-Cockayne form (OMIM ) (Fine et al., 2008). All 3 forms can be caused by mutation in the KRT5 or the KRT14 gene. See {601001} for a rare autosomal recessive form caused by mutation in the KRT14 gene.Davison (1965) referred to generalized distribution of bullous vesicles as epidermolysis simplex bullosa. The condition in which bullae were limited to the hands and feet was referred to as the Cockayne type of epidermolysis bullosa (OMIM ).On the basis of an extensive study in Norway and review of the literature, Gedde-Dahl (1971) arrived at a classification of epidermolysis bullosa. EB simplex in this classification encompassed disorders characterized by bulla formation within the epidermis, basal cell vacuolization, and dissolution of tonofibrils on electron microscopy. The generalized Koebner form and the localized Weber-Cockayne type were believed to be allelic. Gedde-Dahl (1981) recognized at least 16 varieties of epidermolysis bullosa and suggested that dominant EB simplex can be clinically and genetically divided into at least 4 types: the generalized Koebner type, the localized Weber-Cockayne type, the mild Ogna type with fragile skin (OMIM ), and a form with mottled pigmentation (OMIM ).Fine et al. (1991) provided a revised classification of the subtypes of inherited epidermolysis bullosa based on clinical and laboratory criteria.

EPIDERMOLYSIS BULLOSA SIMPLEX, GENERALIZED Is also known as ebs, generalized|epidermolysis bullosa simplex, koebner type

Related symptoms:

  • Fever
  • Hyperkeratosis
  • Nail dystrophy
  • Nail dysplasia
  • Abnormal blistering of the skin


SOURCES: OMIM MENDELIAN

More info about EPIDERMOLYSIS BULLOSA SIMPLEX, GENERALIZED

The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin.

ICHTHYOSIS VULGARIS Is also known as ichthyosis simplex

Related symptoms:

  • Fever
  • Hyperkeratosis
  • Ichthyosis
  • Asthma
  • Eczema


SOURCES: OMIM MESH MENDELIAN

More info about ICHTHYOSIS VULGARIS

Related symptoms:

  • Fever
  • Hyperkeratosis
  • Arthralgia
  • Arthritis
  • Ichthyosis


SOURCES: OMIM MENDELIAN

More info about PSORIASIS 2; PSORS2

Hypohidrosis-enamel hypoplasia-palmoplantar keratoderma-intellectual disability syndrome is a rare, genetic, syndromic intellectual disability disorder characterized by severe intellectual disability with significant speech and language impairment, hypohydrosis (often resulting in hyperthermia) with normal sweat gland appearance, tooth enamel hypoplasia, palmoplantar hyperkeratosis and a high frequency of acquired microcephaly. Mild facial dysmorphism, including lateral flaring of the eyebrows, broad nasal tip, and thick vermilion border, may also be observed.

HYPOHIDROSIS-ENAMEL HYPOPLASIA-PALMOPLANTAR KERATODERMA-INTELLECTUAL DISABILITY SYNDROME Is also known as shaheen syndrome

Related symptoms:

  • Intellectual disability
  • Microcephaly
  • Delayed speech and language development
  • Fever
  • Hyperkeratosis


SOURCES: ORPHANET OMIM MENDELIAN

More info about HYPOHIDROSIS-ENAMEL HYPOPLASIA-PALMOPLANTAR KERATODERMA-INTELLECTUAL DISABILITY SYNDROME

Top 5 symptoms//phenotypes associated to Fever and Palmoplantar keratoderma

Symptoms // Phenotype % cases
Hyperkeratosis Very Common - Between 80% and 100% cases
Ectodermal dysplasia Common - Between 50% and 80% cases
Heat intolerance Common - Between 50% and 80% cases
Epidermal acanthosis Uncommon - Between 30% and 50% cases
Nail dystrophy Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Fever and Palmoplantar keratoderma. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Palmoplantar hyperkeratosis Hypohidrosis Hyperhidrosis Erythroderma Scaling skin Hypotrichosis Ichthyosis Alopecia Hypoplasia of dental enamel

Rare Symptoms - Less than 30% cases

Fragile skin Conical tooth Camptodactyly Anhidrosis Abnormality of the hair Feeding difficulties Sparse eyelashes Widely spaced teeth Psoriasiform dermatitis Cleft palate Absent eyebrow Failure to thrive Hearing impairment Conjunctivitis Patchy alopecia Pili torti Congenital ichthyosiform erythroderma Choanal atresia Parakeratosis Growth delay Erythema Short stature Inflammatory abnormality of the skin Syndactyly Sepsis Abnormal blistering of the skin Nail dysplasia Scarring Skin vesicle Eczema Ectrodactyly Small nail Carious teeth Abnormality of dental enamel Absent eyelashes Intellectual disability Immunodeficiency Hyperpigmentation of the skin Blepharitis Microcephaly Dry skin Orthokeratosis Weight loss Microphthalmia Oligohydramnios Kyphosis Dilatation Postaxial hand polydactyly Specific learning disability Recurrent infections Mental deterioration Abnormality of the ribs Omphalocele Postaxial polydactyly Aganglionic megacolon Intellectual disability, severe Hypoplasia of the corpus callosum Respiratory distress Ventriculomegaly Frontal bossing Renal dysplasia Abnormal vertebral morphology Brain atrophy Cerebellar hypoplasia Hernia Papule Developmental regression Hydronephrosis Photophobia Multicystic kidney dysplasia Umbilical hernia Macrotia Respiratory tract infection Camptodactyly of finger Corneal opacity Hip dislocation Polydactyly Inguinal hernia Cerebral cortical atrophy Platyspondyly Talipes Dementia Severe short stature Astigmatism Pulmonary hypoplasia Recurrent respiratory infections Agenesis of corpus callosum Abnormality of the kidney Delayed skeletal maturation Abnormality of the nail Abnormality of the vertebral column Hemivertebrae Milia Abnormal nasolacrimal system morphology Abnormality of temperature regulation Hyperconvex fingernails Episcleritis Paronychia Cerebral cortical hemiatrophy Hypoplasia of the bladder Scleritis Thin fingernail Abnormal pelvis bone morphology Ichthyosis follicularis Unilateral chest hypoplasia Mottled pigmentation Corneal scarring Asthma Allergic rhinitis Eczematoid dermatitis Orthokeratotic hyperkeratosis Arthralgia Arthritis Dermal atrophy Rheumatoid arthritis Atopic dermatitis Diffuse skin atrophy Delayed speech and language development Hepatitis Postnatal microcephaly Subcortical cerebral atrophy Abnormality of the upper urinary tract Recurrent bacterial infections Oligodactyly Opacification of the corneal stroma Plagiocephaly Abnormality of the hand Urticaria Unilateral renal agenesis Bifid scrotum Intestinal obstruction Keratitis Hydroureter Mixed hearing impairment Absent septum pellucidum Myopia Atonic seizures Submucous cleft hard palate Cheilitis Uveitis Alopecia of scalp Abnormal eyelash morphology Abnormal eyelid morphology Corneal erosion Follicular hyperkeratosis Hypoplastic fingernail Recurrent corneal erosions Olivopontocerebellar atrophy Alopecia totalis Thin eyebrow Oxycephaly Alopecia universalis Intrauterine growth retardation Neoplasm Flexion contracture Palmar hyperkeratosis Adermatoglyphia Cognitive impairment Sparse scalp hair Sparse and thin eyebrow Cutaneous syndactyly Coarse hair Hypoplastic toenails Aplasia/Hypoplasia of the eyebrow Cutaneous finger syndactyly Ridged nail Hypoplasia of teeth Absent facial hair Reticular hyperpigmentation Epidermal hyperkeratosis 2-3 toe cutaneous syndactyly Confusion Dehydration Cutaneous photosensitivity Skin ulcer Recurrent skin infections Poor appetite Disseminated intravascular coagulation Generalized hyperkeratosis Congenital bullous ichthyosiform erythroderma Hypernatremia Diffuse palmoplantar keratoderma Dystrophic fingernails Conjunctival hamartoma Abnormality of the face Peripheral neuropathy Hepatomegaly Skeletal muscle atrophy Tremor Edema Splenomegaly Hepatosplenomegaly Skin rash Pruritus Lymphadenopathy Lymphoma Thickened skin Dystrophic toenail Neoplasm of the skin Ectropion Irregular hyperpigmentation Gangrene Abnormality of the pleura Lichenification T-cell lymphoma Abnormal lymphocyte morphology Abnormal immunoglobulin level Cutaneous T-cell lymphoma Premature loss of teeth Fragile nails Hypernatremic dehydration Pain Cryptorchidism Ankyloblepharon Supernumerary nipple Agenesis of permanent teeth Sparse body hair Keratoconjunctivitis sicca Abnormal facial shape Pustule Chronic sinusitis Trismus Selective tooth agenesis Skin erosion Plantar hyperkeratosis Hyperconvex nail 2-3 toe syndactyly Oval face Lacrimal duct atresia Bilateral choanal atresia 3-4 toe syndactyly Fibrous syngnathia Vaginal dryness Otitis externa Seizures Global developmental delay Scoliosis Nystagmus Muscular hypotonia Anonychia Hammertoe Wide nasal bridge Toe syndactyly Ventricular septal defect Abnormality of the dentition Hypospadias Patent ductus arteriosus Micropenis Narrow mouth Conductive hearing impairment Abnormality of the nervous system Cleft lip Sparse hair Microtia Oral cleft Brittle hair Cleft upper lip Hypoplasia of the maxilla Hypodontia Otitis media Microdontia Fine hair Split hand Recurrent otitis media Sinusitis Hoarse voice Increased body weight Atresia of the external auditory canal Mild microcephaly


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