Fever, and Migraine

Diseases related with Fever and Migraine

In the following list you will find some of the most common rare diseases related to Fever and Migraine that can help you solving undiagnosed cases.

Top matches:

Essential tremor may be the most common human movement disorder. The main feature of essential tremor is postural tremor of the arms, but the head, legs, trunk, voice, jaw, and facial muscles also may be involved. Aggravated by emotions, hunger, fatigue, and temperature extremes, the condition may cause a functional disability or even incapacitation. Autosomal dominant inheritance can be demonstrated in most families (summary by Higgins et al., 1997).Deng et al. (2007) provided a detailed review of the genetics of essential tremor. Genetic Heterogeneity of Essential TremorOther forms of hereditary essential tremor include ETM2 (OMIM ), mapped to chromosome 2p25-p22; ETM3 (OMIM ), mapped to chromosome 6p23; ETM4 (OMIM ), caused by mutation in the FUS gene (OMIM ) on chromosome 16p11; and ETM5 (OMIM ), caused by mutation in the TENM4 gene (OMIM ) on chromosome 11q14.

TREMOR, HEREDITARY ESSENTIAL, 1; ETM1 Is also known as fet1|tremor, familial essential, 1

Related symptoms:

  • Hearing impairment
  • Ataxia
  • Cognitive impairment
  • Dysarthria
  • Fever


SOURCES: OMIM MENDELIAN

More info about TREMOR, HEREDITARY ESSENTIAL, 1; ETM1

DFNA34 is an autosomal dominant form of postlingual, slowly progressive sensorineural hearing loss with variable severity and variable additional features. Some patients have pure hearing loss without significant additional features, whereas some patients have features of an autoinflammatory disorder with systemic manifestations, including periodic fevers, arthralgias, and episodic urticaria. The disorder results from abnormally increased activation of the inflammatory pathway, and treatment with an IL1 receptor antagonist (see {147679}) may be effective if started early (summary by Nakanishi et al., 2017).

Related symptoms:

  • Hearing impairment
  • Sensorineural hearing impairment
  • Fever
  • Edema
  • Headache


SOURCES: OMIM MENDELIAN

More info about DEAFNESS, AUTOSOMAL DOMINANT 34, WITH OR WITHOUT INFLAMMATION; DFNA34

Women show menstrual cycle-dependent physiologic changes in relation to sex hormone levels. Because ovulation triggers a significant change in the hormonal milieu that is similar to local inflammation, a 0.5 to 1.0 degree Celsius increase in basal body temperature after ovulation is commonly associated with progesterone secretion and is believed to be triggered by the induction of several inflammatory cytokines. Rare menstrual cycle-dependent febrile episodes have been reported, some of which have shown a luteal-phase-dependent pattern (summary by Jiang et al., 2012).

Related symptoms:

  • Ataxia
  • Fever
  • Tremor
  • Myalgia
  • Lower limb muscle weakness


SOURCES: OMIM MENDELIAN

More info about PERIODIC FEVER, MENSTRUAL CYCLE-DEPENDENT

Other less relevant matches:

Medium match DRAVET SYNDROME

Dravet syndrome (DS) is a genetic epilepsy of childhood characterized by a variety of drug-resistant seizures often induced by fever, presenting in previously healthy children, and which frequently leads to cognitive and motor impairment.

DRAVET SYNDROME Is also known as smei|severe myoclonus epilepsy of infancy|ds|severe myoclonic epilepsy of infancy|dravet syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Microcephaly
  • Ataxia


SOURCES: OMIM ORPHANET MENDELIAN

More info about DRAVET SYNDROME

MIGRAINE, FAMILIAL HEMIPLEGIC, 2; FHM2 Is also known as mhp2

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Hearing impairment
  • Ataxia


SOURCES: OMIM MENDELIAN

More info about MIGRAINE, FAMILIAL HEMIPLEGIC, 2; FHM2

MIGRAINE, FAMILIAL HEMIPLEGIC, 1; FHM1 Is also known as mhp1|fhm

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Hearing impairment


SOURCES: OMIM MENDELIAN

More info about MIGRAINE, FAMILIAL HEMIPLEGIC, 1; FHM1

Classic Hodgkin lymphoma is a lymph node cancer of germinal center B-cell origin. Hodgkin lymphoma tumors consist of a minority of malignant cells, known as 'Reed-Sternberg' (RS) cells, mixed with reactive lymphocytes and other benign inflammatory cells. A defining feature of RS cells is the presence of 2 nuclei (summary by Salipante et al., 2009).

LYMPHOMA, HODGKIN, CLASSIC; CHL Is also known as hodgkin disease

Related symptoms:

  • Ataxia
  • Neoplasm
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


SOURCES: OMIM ORPHANET MENDELIAN

More info about LYMPHOMA, HODGKIN, CLASSIC; CHL

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Hearing impairment


SOURCES: OMIM MENDELIAN

More info about CYCLIC VOMITING SYNDROME; CVS

Medium match TAKAYASU ARTERITIS

Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.

TAKAYASU ARTERITIS Is also known as young female arteritis|aortic arch syndrome|pulseless disease

Related symptoms:

  • Seizures
  • Muscle weakness
  • Anemia
  • Hypertension
  • Fever


SOURCES: ORPHANET OMIM MENDELIAN

More info about TAKAYASU ARTERITIS

Episodic ataxia is a genetically heterogeneous neurologic condition characterized by spells of incoordination and imbalance, often associated with progressive ataxia. Episodic ataxia type 2 is the most common form of EA (Jen et al., 2007).For a discussion of genetic heterogeneity of episodic ataxia, see EA1 (OMIM ).

EPISODIC ATAXIA, TYPE 2; EA2 Is also known as cerebellopathy, hereditary paroxysmal|ataxia, familial paroxysmal|capa|acetazolamide-responsive hereditary paroxysmal cerebellar ataxia|apca|cerebellar ataxia, paroxysmal, acetazolamide-responsive|ataxia, episodic, with nystagmus|episodic ataxia, nystagmu

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Scoliosis


SOURCES: OMIM MENDELIAN

More info about EPISODIC ATAXIA, TYPE 2; EA2

Top 5 symptoms//phenotypes associated to Fever and Migraine

Symptoms // Phenotype % cases
Ataxia Common - Between 50% and 80% cases
Tremor Common - Between 50% and 80% cases
Seizures Common - Between 50% and 80% cases
Hearing impairment Uncommon - Between 30% and 50% cases
Global developmental delay Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Fever and Migraine. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Fatigue Intellectual disability Headache Motor delay Abnormal cerebellum morphology Hyperhidrosis Vomiting Myalgia Muscle weakness Paresthesia Edema Hemiplegia Anorexia Nausea Dysarthria Depressivity Nystagmus Cognitive impairment Behavioral abnormality Generalized hypotonia Pain Vertigo

Rare Symptoms - Less than 30% cases

Hemoptysis Gait ataxia Photophobia Confusion Epileptic encephalopathy Focal-onset seizure Hemiparesis Coma Intention tremor Diplopia Tinnitus Chest pain Stroke Dysphasia Drowsiness Episodic ataxia Migraine with aura Nausea and vomiting Transient unilateral blurring of vision Weight loss Cerebellar atrophy Myopathy Loss of consciousness Focal impaired awareness seizure Developmental regression Muscular hypotonia Dystonia Cerebral atrophy Rigidity Anxiety Mental deterioration Abnormality of extrapyramidal motor function Arthralgia Arthritis Microcephaly Lymphadenopathy Encephalopathy EEG abnormality Ascending tubular aorta aneurysm Vestibular dysfunction Attention deficit hyperactivity disorder Lethargy Arteritis Cerebellar vermis atrophy Gaze-evoked nystagmus Abnormal autonomic nervous system physiology Optic atrophy Autism Exercise intolerance Myotonia Ophthalmoparesis Incoordination CNS hypomyelination Pallor Diarrhea Abdominal pain Malignant hyperthermia Saccadic smooth pursuit Increased inflammatory response Poor appetite Cellular immunodeficiency Lung adenocarcinoma Monoclonal immunoglobulin M proteinemia Rhabdomyolysis Gastrointestinal dysmotility Impaired lymphocyte transformation with phytohemagglutinin Polyclonal elevation of IgM Growth delay Strabismus Hypertensive crisis Cardiomyopathy Skeletal muscle atrophy Abnormality of mitochondrial metabolism Sleep apnea Anemia Psoriasiform dermatitis Myocardial infarction Subcutaneous nodule Abnormal endocardium morphology Skin ulcer Vasculitis Aortic regurgitation Abnormal heart valve morphology Pulmonary arterial hypertension Gangrene Cerebral ischemia Reduced consciousness/confusion Osteolysis Abnormal aortic valve morphology Inflammatory abnormality of the eye Abnormal pattern of respiration Amaurosis fugax Ventriculomegaly Arterial stenosis Dilatation Hypertension Horizontal nystagmus Progressive cerebellar ataxia Gastrointestinal infarctions Scoliosis Generalized muscle weakness Muscle cramps Hypoplasia of the corpus callosum Postural instability Apnea Facial palsy Proximal muscle weakness Hypertrophic cardiomyopathy Retinopathy Neurological speech impairment Hodgkin lymphoma Phonophobia Bone marrow hypocellularity Generalized myoclonic seizures Recurrent spontaneous abortion Myoclonus Hyperactivity Abnormal pyramidal sign Severe global developmental delay Generalized tonic-clonic seizures Febrile seizures Hepatitis Generalized-onset seizure Status epilepticus Cutaneous photosensitivity Postnatal microcephaly Cerebral visual impairment Progressive microcephaly Absence seizures Increased circulating cortisol level Lower limb muscle weakness Atonic seizures Personality changes Gait disturbance Dementia Hypoglycemia Abnormality of movement Parkinsonism Memory impairment Postural tremor Resting tremor Cervical lymphadenopathy Hand tremor Head tremor Kinetic tremor Sensorineural hearing impairment Conjunctivitis Progressive hearing impairment Urticaria Neurodevelopmental delay Generalized tonic-clonic seizures with focal onset Bone pain Peripheral neuropathy Hallucinations Agitation Visual hallucinations Auditory hallucinations Dyscalculia Psychotic episodes Neoplasm Hepatomegaly Retinal degeneration Respiratory insufficiency Splenomegaly Skin rash Cough Leukemia Pruritus Lymphoma Psychosis Personality disorder Multifocal seizures Intellectual disability, moderate Hemiclonic seizures Focal clonic seizures Psychomotor retardation Obtundation status Delayed speech and language development Blindness Intellectual disability, mild Autistic behavior Migraine without aura Dysmetria Apraxia Aphasia Blurred vision Severe hearing impairment Restlessness Borderline personality disorder Downbeat nystagmus


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