Fever, and Ichthyosis

Diseases related with Fever and Ichthyosis

In the following list you will find some of the most common rare diseases related to Fever and Ichthyosis that can help you solving undiagnosed cases.

Top matches:

Medium match ICHTHYOSIS VULGARIS

The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin.

ICHTHYOSIS VULGARIS Is also known as ichthyosis simplex

Related symptoms:

  • Fever
  • Hyperkeratosis
  • Ichthyosis
  • Asthma
  • Eczema


SOURCES: OMIM MESH MENDELIAN

More info about ICHTHYOSIS VULGARIS

Medium match PSORIASIS 2; PSORS2

Related symptoms:

  • Fever
  • Hyperkeratosis
  • Arthralgia
  • Arthritis
  • Ichthyosis


SOURCES: OMIM MENDELIAN

More info about PSORIASIS 2; PSORS2

Muckle-Wells syndrome (MWS) is characterized by episodic skin rash, arthralgias, and fever associated with late-onset sensorineural deafness and renal amyloidosis (Dode et al., 2002).See also familial cold-induced autoinflammatory syndrome-1 (FCAS1, CAPS1; {120100}), an allelic disorder with overlapping clinical features.

MUCKLE-WELLS SYNDROME; MWS Is also known as caps2|uda syndrome|urticaria-deafness-amyloidosis syndrome|cryopyrin-associated periodic syndrome 2

Related symptoms:

  • Seizures
  • Hearing impairment
  • Sensorineural hearing impairment
  • Pain
  • Anemia


SOURCES: OMIM MENDELIAN

More info about MUCKLE-WELLS SYNDROME; MWS

Other less relevant matches:

Medium match NETHERTON SYNDROME

Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations.

NETHERTON SYNDROME Is also known as erythroderma, ichthyosiform, with hypotrichosis and hyper-ige|comÈl-netherton syndrome|bamboo hair syndrome|comel-netherton syndrome|ns|netherton disease

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Growth delay


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about NETHERTON SYNDROME

Muckle-Wells syndrome (MWS) is an intermediate form of cryopyrin-associated periodic syndrome (CAPS; see this term) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type).

MUCKLE-WELLS SYNDROME Is also known as neutrophilic urticaria

Related symptoms:

  • Short stature
  • Anemia
  • Hepatomegaly
  • Fever
  • Optic atrophy


SOURCES: ORPHANET MENDELIAN

More info about MUCKLE-WELLS SYNDROME

Medium match BLAU SYNDROME

Blau syndrome (BS) is a rare systemic inflammatory disease characterized by early onset granulomatous arthritis, uveitis and skin rash. BS now refers to both the familial and sporadic (formerly early-onset sarcoidosis) form of the same disease. The proposed term pediatric granulomatous arthritis is currently questioned since it fails to represent the systemic nature of the disease.

Related symptoms:

  • Cataract
  • Anemia
  • Hypertension
  • Fever
  • Splenomegaly


SOURCES: ORPHANET MENDELIAN

More info about BLAU SYNDROME

Gaucher disease type 2 is the acute neurological form of Gaucher disease (GD; see this term). It is characterized by early-onset and severe neurological involvement of the brainstem, associated with an organomegaly and generally leading to death before the age of 2.

GAUCHER DISEASE TYPE 2 Is also known as infantile cerebral gaucher disease|acute neuronopathic gaucher disease

Related symptoms:

  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Microcephaly
  • Scoliosis


SOURCES: ORPHANET MENDELIAN

More info about GAUCHER DISEASE TYPE 2

Medium match H SYNDROME

H syndrome is a systemic inherited histiocytosis, with characteristic cutaneous findings accompanying systemic manifestations. H syndrome refers to the major clinical findings of hyperpigmentation, hypertrichosis, hepatosplenomegaly, heart anomalies, hearing loss, hypogonadism, low height, and occasionally, hyperglycemia/diabetes mellitus. Due to overlapping clinical features, H syndrome is now considered to include pigmented hypertrichosis with insulin dependent diabetes mellitus syndrome (PHID), Faisalabad histiocytosis (FHC) and familial sinus histiocytosis with massive lymphadenopathy (FSHML).

H SYNDROME Is also known as sinus histiocytosis and massive lymphadenopathy|hjcd|shml|hyperpigmentation, cutaneous, with hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism with or without hearing loss|h syndrome|faisalabad histiocytosis|pigmented hypertrichosis wi

Related symptoms:

  • Global developmental delay
  • Short stature
  • Generalized hypotonia
  • Hearing impairment
  • Growth delay


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about H SYNDROME

Low match MELAS

MELAS (Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke) syndrome is a rare progressive multisystemic disorder characterized by encephalomyopathy, lactic acidosis, and stroke-like episodes. Other features include endocrinopathy, heart disease, diabetes, hearing loss, and neurological and psychiatric manifestations.

MELAS Is also known as mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes|melas syndrome|mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Hearing impairment


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about MELAS

HELIX SYNDROME; HELIX Is also known as hypohidrosis, electrolyte imbalance, lacrimal gland dysfunction, ichthyosis, and xerostomia

Related symptoms:

  • Pain
  • Renal insufficiency
  • Dry skin
  • Ichthyosis
  • Postural instability


SOURCES: OMIM MENDELIAN

More info about HELIX SYNDROME; HELIX

Top 5 symptoms//phenotypes associated to Fever and Ichthyosis

Symptoms // Phenotype % cases
Anemia Common - Between 50% and 80% cases
Dyspnea Uncommon - Between 30% and 50% cases
Failure to thrive Uncommon - Between 30% and 50% cases
Short stature Uncommon - Between 30% and 50% cases
Global developmental delay Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Fever and Ichthyosis. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Hepatomegaly Nephropathy Skin rash Abdominal pain Seizures Lymphadenopathy Arthralgia Splenomegaly Elevated erythrocyte sedimentation rate Delayed puberty Malabsorption Pulmonary arterial hypertension Xerostomia Urticaria Dry skin Progressive sensorineural hearing impairment Hepatosplenomegaly Scaling skin Epidermal acanthosis Growth delay Delayed skeletal maturation Apnea Myalgia Nephrotic syndrome Pain Diarrhea Psoriasiform dermatitis Arthritis Fatigue Hyperkeratosis Atopic dermatitis Renal insufficiency Hearing impairment Sensorineural hearing impairment

Rare Symptoms - Less than 30% cases

Episcleritis Hypertonia Congestive heart failure Photophobia Dystonia Kyphosis Encephalopathy Erythema Glaucoma Arrhythmia Vomiting Motor delay Edema Respiratory distress Dysphagia Flexion contracture Ataxia Microcephaly Generalized hypotonia Cataract Visual loss Aortic aneurysm Hyperpigmentation of the skin Camptodactyly of finger Retinopathy Abnormality of the liver Hypertension Anorexia Dementia Hypogonadism Histiocytosis Spontaneous hematomas Hypertelorism Ptosis Hyperreflexia Ventriculomegaly Diabetes mellitus Aspiration pneumonia Hypothyroidism Polyneuropathy Amenorrhea Bilateral sensorineural hearing impairment Hypertrichosis Gingival overgrowth Type I diabetes mellitus Postural instability Hyponatremia Myoclonus Generalized myoclonic seizures Jaundice Developmental regression Feeding difficulties in infancy Lethargy Ophthalmoplegia Nausea Epistaxis Bilateral ptosis Decreased body weight Cachexia Aspiration Cardiac arrest Elbow flexion contracture Osteolysis Purpura Optic atrophy Gastroesophageal reflux Pruritus Inflammatory abnormality of the skin Heat intolerance Intracranial hemorrhage Episodic fever Eczema Congenital ichthyosiform erythroderma Congenital nonbullous ichthyosiform erythroderma Allergic rhinitis Asthma Recurrent aphthous stomatitis Leukocytosis Alopecia Recurrent respiratory infections Renal amyloidosis Conjunctivitis Weight loss Stage 5 chronic kidney disease Vasculitis Abnormality of the skin Coma Intellectual disability Paresthesia Dysmetria Nephrocalcinosis Confusion Vertigo Anal atresia Carious teeth Nausea and vomiting Lactic acidosis Congenital cataract Arthrogryposis multiplex congenita Generalized tonic-clonic seizures Dilated cardiomyopathy Neurological speech impairment Stroke Attention deficit hyperactivity disorder Hypokalemia Nyctalopia Polyuria Peripheral axonal neuropathy Proximal tubulopathy Polymicrogyria Hypohidrosis Clonus Cerebral visual impairment Hallucinations Abnormality of retinal pigmentation Left ventricular hypertrophy Involuntary movements Hemiparesis Atrial fibrillation Ventricular hypertrophy Psychosis Status epilepticus Type II diabetes mellitus Generalized-onset seizure Hirsutism Abnormality of the cardiovascular system Pigmentary retinopathy Cerebral calcification Specific learning disability Hip dysplasia Memory impairment Increased serum lactate Migraine Sensory impairment Protruding ear Abnormal cerebellum morphology Muscle cramps Sudden cardiac death Proteinuria Abnormality of the pinna Cervical lymphadenopathy Dysarthria Hypermagnesemia Peripheral neuropathy Visual impairment Feeding difficulties Cognitive impairment Muscular hypotonia Muscle weakness Nystagmus Seborrheic keratosis Retroperitoneal fibrosis Upper eyelid edema Bilateral camptodactyly Stiff skin Tremor Snoring Panniculitis Facial telangiectasia Myelofibrosis Generalized lymphadenopathy Corneal arcus Hyperplasia of the maxilla Broad finger Pancreatic hypoplasia Abnormality of cardiovascular system physiology Chronic rhinitis Reticulocytopenia Skin nodule Skeletal muscle atrophy Gait disturbance Mental deterioration Alacrima Hypertrophic cardiomyopathy Anhidrosis EMG abnormality Anxiety EEG abnormality Hyperparathyroidism Acidosis Autism Gait ataxia Cerebral cortical atrophy Osteoporosis Rod-cone dystrophy Cerebellar hypoplasia Hypocalciuria Respiratory insufficiency Constipation Elevated serum creatine phosphokinase Hyporeflexia Areflexia Depressivity Cerebral atrophy Headache Abnormality of the dentition Cerebellar atrophy Myopathy Blindness Cardiomyopathy Short neck Secondary hyperparathyroidism Truncal ataxia Reduced tendon reflexes Generalized hirsutism Hashimoto thyroiditis Cardiorespiratory arrest Delusions Renal Fanconi syndrome Transient ischemic attack Posterior subcapsular cataract Progressive external ophthalmoplegia Mitochondrial myopathy Hypoparathyroidism Heart block Vitiligo Neonatal hypoglycemia Abnormality of visual evoked potentials Drowsiness Abnormal nerve conduction velocity Distal arthrogryposis Pulmonary embolism Primary adrenal insufficiency Tubulointerstitial abnormality Psychotic episodes Abnormality of immune system physiology Thyroiditis Rhabdomyolysis Hyperthyroidism Abnormality of the cerebellar vermis Crohn's disease Basal ganglia calcification Hemeralopia Facial diplegia Aortic dissection Spotty hypopigmentation Reduced consciousness/confusion Abnormality of peripheral nerve conduction Hemianopia Retinal pigment epithelial atrophy Speech apraxia Abnormality of the renal tubule Episodic vomiting Motor polyneuropathy Left ventricular failure Seborrheic dermatitis Stroke-like episode Anterior hypopituitarism Gait imbalance Cerebral ischemia Auditory hallucinations Wolff-Parkinson-White syndrome Dysesthesia Increased CSF lactate Psychomotor deterioration Muscle fiber atrophy Writer's cramp Persistence of primary teeth Visual hallucinations Leber optic atrophy Gastroparesis Amaurosis fugax Tubulointerstitial nephritis Renal tubular dysfunction Abnormal macular morphology Paronychia Hypogonadotrophic hypogonadism Growth abnormality Ophthalmoparesis Abnormality of mitochondrial metabolism Bilateral intracranial calcifications Hemiplegia Hypercalciuria Morphological abnormality of the vestibule of the inner ear Decreased nerve conduction velocity Morphological abnormality of the inner ear Atrioventricular block Chronic kidney disease Prominent ear helix Hypotension Easy fatigability Intestinal obstruction Hyperkinesis Nephrolithiasis Goiter Schizophrenia Mutism Hypopigmented skin patches Ischemic stroke Ragged-red muscle fibers Ileus External ophthalmoplegia Pancreatitis Macular degeneration Exercise intolerance Personality changes Aplasia/Hypoplasia of the cerebellum Abnormal mitochondrial morphology Visual field defect Edema of the dorsum of hands Cochlear malformation Progressive night blindness Glomerulopathy Cochlear degeneration Abnormal mitochondrial shape Paralytic ileus Abnormal cochlea morphology Vertebral fusion Recurrent pharyngitis Multiple lipomas Prolonged QT interval Hyperkalemia Bifid scrotum Dysphasia Homonymous hemianopia Vestibular dysfunction Aphasia Bundle branch block Adrenal insufficiency Abnormality of acid-base homeostasis Overlapping toe Abnormality of neuronal migration Focal segmental glomerulosclerosis Hemiplegia/hemiparesis Mask-like facies Episodic quadriplegia Nasal obstruction Intellectual disability, mild Decreased serum testosterone level Synovitis Strabismus Scoliosis Abnormal inflammatory response Retrobulbar optic neuritis Large vessel vasculitis Clear cell renal cell carcinoma Polyarticular arthritis Abnormal choroid morphology Abnormal salivary gland morphology Iridocyclitis Posterior uveitis Erythema nodosum Abnormality of the retinal vasculature Spasticity Abnormality of the optic nerve Abnormal cranial nerve morphology Joint swelling Pericarditis Keratitis Skin ulcer Limitation of joint mobility Papule Facial palsy Hernia of the abdominal wall Abnormality of the nose Broad foot Abnormal facial shape Intrauterine growth retardation Restrictive ventilatory defect Ascites Bone pain Progressive microcephaly Hydrops fetalis Thickened skin Cholestasis Progressive neurologic deterioration Pancytopenia Decreased fetal movement Cyanosis Brain atrophy Syncope Abnormal bleeding Pulmonary hypoplasia Thrombocytopenia Hepatic failure Cirrhosis Abnormality of eye movement Corneal opacity Cough Pallor Irritability Elevated hepatic transaminase Rigidity Hypoglycemia Umbilical hernia Osteopenia Polyhydramnios Uveitis Abnormality of the voice Knee flexion contracture Microscopic hematuria Sparse and thin eyebrow Sparse scalp hair Fine hair Dehydration Decreased antibody level in blood Sepsis Hydronephrosis Recurrent infections Rigors Band keratopathy Cystinuria Chills Papilledema Aminoaciduria Abnormality of the mouth Amyloidosis Meningitis Hematuria Abnormality of the skeletal system Diffuse skin atrophy Orthokeratosis Parakeratosis Rheumatoid arthritis Dermal atrophy Orthokeratotic hyperkeratosis Eczematoid dermatitis Abnormality of the hair Sparse eyelashes Abnormal palate morphology Trichorrhexis nodosa Cranial nerve paralysis Abnormality of the genital system Pes cavus Abnormality of metabolism/homeostasis Macrocephaly IgE-mediated food allergy Brittle scalp hair Hypernatremic dehydration Hypernatremia Immunologic hypersensitivity Angioedema Increased IgE level Allergy Acanthosis nigricans Verrucae Villous atrophy Hypothermia Severe postnatal growth retardation Irregular hyperpigmentation Abnormality of the musculature Ectopic kidney Malnutrition Emphysema Erythroderma Brittle hair Recurrent skin infections Abnormal intestine morphology Hypocalcemia Hyperbilirubinemia Communicating hydrocephalus Proptosis Recurrent fractures Flat face Cleft upper lip Abnormality of the foot Hypotrichosis Pectus carinatum Abnormal cardiac septum morphology Abnormality of the kidney Camptodactyly Low-set, posteriorly rotated ears Conductive hearing impairment Pes planus Micropenis Growth hormone deficiency Posteriorly rotated ears Severe short stature Pneumonia Abnormal heart morphology Patent ductus arteriosus Clinodactyly Hernia Atrial septal defect Hydrocephalus Anteverted nares Ventricular septal defect Frontal bossing Full cheeks Wide intermamillary distance Brachydactyly Stridor Varicose veins Abnormal eyebrow morphology Enlarged kidney Exocrine pancreatic insufficiency Severe sensorineural hearing impairment Polycythemia Scleroderma Lipoatrophy Microcytic anemia Increased antibody level in blood Hallux valgus Hyperglycemia Lipodystrophy Decreased testicular size Sleep apnea Azoospermia Plagiocephaly Hypergonadotropic hypogonadism Gynecomastia Telangiectasia Bronchiectasis Primary amenorrhea Hypertriglyceridemia Blue sclerae Cardiomegaly Mitral valve prolapse Overgrowth Wide nasal bridge Epicanthus Oculomotor apraxia Abnormality of coagulation Increased serum ferritin Hepatocellular carcinoma Epileptic spasms Limb hypertonia Protuberant abdomen Atrophy/Degeneration affecting the brainstem Poor eye contact Bulbar palsy Exertional dyspnea Hypokinesia Interstitial pulmonary abnormality Petechiae Opisthotonus Hypomagnesemia Menorrhagia Athetosis Heart murmur Akinesia Clubbing Ectropion Abnormality of the thorax Portal hypertension Cholelithiasis Poor suck Hyperammonemia Leukopenia Fetal akinesia sequence Bulbar signs EEG with temporal sharp waves Abducens palsy Slowed horizontal saccades Cardiac valve calcification Abnormal platelet aggregation Hematological neoplasm Decreased beta-glucocerebrosidase protein and activity Erlenmeyer flask deformity of the femurs CSF pleocytosis Orthopnea Laryngeal stridor Giant cell hepatitis Intestinal bleeding Subcutaneous hemorrhage Axial dystonia Trismus Hemophagocytosis Eclabion Abnormal pattern of respiration Generalized osteosclerosis Restrictive deficit on pulmonary function testing Avascular necrosis of the capital femoral epiphysis Abnormality of the spleen Hypoxemia Abnormality of the larynx Multiple myeloma Supranuclear gaze palsy Nonimmune hydrops fetalis Slow saccadic eye movements Generalized anhidrosis


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