Fever, and Hematuria
Diseases related with Fever and Hematuria
In the following list you will find some of the most common rare diseases related to Fever and Hematuria that can help you solving undiagnosed cases.
Medium match HEME OXYGENASE 1 DEFICIENCY; HMOX1D
- Growth delay
More info about HEME OXYGENASE 1 DEFICIENCY; HMOX1D
Medium match C3 GLOMERULONEPHRITIS
Immunodeficiency due to a classical component pathway complement deficiency is a primary immunodeficiency due to a deficiency in either complement components C1q, C1r, C1s, C2 or C4 characterized by increased susceptibility to bacterial infections, particularly with encapsulated bacteria, and increased risk for autoimmune disease. Most commonly, these include systemic lupus erythematosus (SLE), SLE-like disease, Henoch-Schonlein purpura, polymyositis and arthralgia. Disease severity is variable and dependent on the complement affected.
IMMUNODEFICIENCY DUE TO A CLASSICAL COMPONENT PATHWAY COMPLEMENT DEFICIENCY Is also known as immunodeficiency due to c1, c4, or c2 component complement deficiency|immunodeficiency due to an early component of complement deficiencyRelated symptoms:
- Renal insufficiency
More info about IMMUNODEFICIENCY DUE TO A CLASSICAL COMPONENT PATHWAY COMPLEMENT DEFICIENCY
Other less relevant matches:
Medium match IMMUNODEFICIENCY WITH FACTOR I ANOMALY
Immunodeficiency with factor I anomaly is a rare, genetic, primary immunodeficiency disease characterized by increased susceptibility to recurrent, usually severe, infections (particularly by Neisseria meningitidis, Haemophilus influenzae and Streptococcus pneumonia), typically manifesting as otitis, sinusitis, bronchitis, pneumonia, and/or meningitis. Autoimmune disease (e.g. systemic lupus erythematosus, glomerulonephritis) and atypical hemolytic uremic syndrome may be associated. Laboratory serum analysis reveals, in addition to diminished or undetectable complement factor I, variably decreased complement C3, complement factor B and complement factor H.
IMMUNODEFICIENCY WITH FACTOR I ANOMALY Is also known as complement component 3 inactivator deficiency|c3 inactivator deficiencyRelated symptoms:
- Renal insufficiency
- Recurrent infections
- Recurrent respiratory infections
More info about IMMUNODEFICIENCY WITH FACTOR I ANOMALY
Medium match NEPHROBLASTOMA
Nephroblastoma is the most frequent malignant renal tumor in children and is associated with an abnormal proliferation of cells that resemble the kidney cells of an embryo (metanephroma), leading to the term embryonal tumor.
NEPHROBLASTOMA Is also known as wilms tumor|nephroblastoma|renal embryonic tumorRelated symptoms:
- Intellectual disability
- Renal insufficiency
More info about NEPHROBLASTOMA
Medium match UROFACIAL SYNDROME 1; UFS1
The urofacial syndrome (UFS) is a rare autosomal recessive disease characterized by a severe and early-onset form of dysfunctional urinary voiding. Affected individuals usually present prenatally or in early childhood with grossly distorted renal tracts, comprising dysmorphic bladders and dilatation of the ureter and renal pelvis. They are at high risk of vesicoureteral reflux (VUR), with ascending bacterial infection leading to kidney damage, hypertension, and renal failure. One-third of UFS children also experience constipation or fecal soiling, suggesting that the pathophysiology of the syndrome encompasses a broader functional impairment of elimination. In addition, affected individuals have a characteristic facial grimace when trying to smile (summary by Daly et al., 2010).
UROFACIAL SYNDROME 1; UFS1 Is also known as facial palsy, partial, with urinary abnormalities|ochoa syndrome|hydronephrosis with peculiar facial expression|urofacial syndrome|inverted smile and occult neuropathic bladder|ufsRelated symptoms:
- Abnormal facial shape
More info about UROFACIAL SYNDROME 1; UFS1
Typical hemolytic uremic syndrome is characterized by acute renal failure, thrombocytopenia, and microangiopathic hemolytic anemia associated with distorted erythrocytes ('burr cells'). The vast majority of cases (90%) are sporadic, occur in children under 3 years of age, and are associated with epidemics of diarrhea caused by verotoxin-producing E. coli. The death rate is very low, about 30% of cases have renal sequelae, and there is usually no relapse of the disease. This form of HUS usually presents with a diarrhea prodrome (thus referred to as D+HUS) and has a good prognosis in most cases. In contrast, a subgroup of patients with HUS have an atypical presentation (aHUS or D-HUS) without a prodrome of enterocolitis and diarrhea and have a much poorer prognosis, with a tendency to relapse and frequent development of end-stage renal failure or death. These cases tend to be familial. Both autosomal recessive and autosomal dominant inheritance have been reported (Goodship et al., 1997; Taylor, 2001; Veyradier et al., 2003; Noris et al., 2003). Noris and Remuzzi (2009) provided a detailed review of atypical HUS.
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1; AHUS1 Is also known as ahus, susceptibility to, 1Related symptoms:
- Cognitive impairment
More info about HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1; AHUS1
Medium match AMYLOIDOSIS, FAMILIAL VISCERAL
AMYLOIDOSIS, FAMILIAL VISCERAL Is also known as german type amyloidosis|amyloidosis, systemic nonneuropathic|amyloidosis viii|amyloidosis, familial renal|ostertag type amyloidosisRelated symptoms:
- Hearing impairment
- Peripheral neuropathy
More info about AMYLOIDOSIS, FAMILIAL VISCERAL
Medium match MAJEED SYNDROME
Majeed syndrome is a rare genetic multisystemic disorder characterized by chronic recurrent multifocal osteomyelitis, congenital dyserythropoietic anemia, which may be accompanied by neutrophilic dermatosis.
MAJEED SYNDROME Is also known as chronic recurrent multifocal osteomyelitis-congenital dyserythropoietic anemia-neutrophilic dermatosis syndromeRelated symptoms:
- Failure to thrive
- Flexion contracture
More info about MAJEED SYNDROME
Medium match CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA
Congenital thrombotic thrombocytopenic purpura is the hereditary form of thrombotic thrombocytopenic purpura (TTP; see this term) characterized by profound peripheral thrombocytopenia, microangiopathic hemolytic anemia (MAHA) and single or multiple organ failure of variable severity.
CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA Is also known as congenital ttp|microangiopathic hemolytic anemia|thrombotic microangiopathy, familial|microangiopathic hemolytic anemia, congenital|congenital adamts-13 deficiency|upshaw factor, deficiency of|uss|thrombotic thrombocytopenic purpura, familial|familial ttpRelated symptoms:
More info about CONGENITAL THROMBOTIC THROMBOCYTOPENIC PURPURA
Top 5 symptoms//phenotypes associated to Fever and Hematuria
|Symptoms // Phenotype||% cases|
|Proteinuria||Very Common - Between 80% and 100% cases|
|Renal insufficiency||Common - Between 50% and 80% cases|
|Hypertension||Uncommon - Between 30% and 50% cases|
|Nephropathy||Uncommon - Between 30% and 50% cases|
|Glomerulonephritis||Uncommon - Between 30% and 50% cases|
Other less frequent symptoms
Patients with Fever and Hematuria. may also develop some of the following symptoms:
Uncommon Symptoms - Between 30% and 50% casesSkin rash Pain Microscopic hematuria Anemia Hemolytic-uremic syndrome Acute kidney injury Decreased serum complement factor I Purpura Stage 5 chronic kidney disease Abdominal pain Weight loss Hemolytic anemia Hepatomegaly Edema
Rare Symptoms - Less than 30% casesHeadache Schistocytosis Sepsis Recurrent urinary tract infections Splenomegaly Decreased serum complement factor H Pyelonephritis Decreased serum complement C3 Reticulocytosis Decreased serum complement factor B Glomerulopathy Neoplasm Microangiopathic hemolytic anemia Elevated serum creatinine Keratitis Pneumonia Hemiparesis Coma Thrombocytopenia Membranoproliferative glomerulonephritis IgA deposition in the glomerulus Macroscopic hematuria Mesangial hypercellularity Systemic lupus erythematosus Diarrhea Recurrent infections Increased blood urea nitrogen Arthralgia Meningitis Seizures Cardiomyopathy Optic neuropathy Failure to thrive Generalized amyloid deposition Renal amyloidosis Albuminuria Restrictive cardiomyopathy Enterocolitis Azotemia Complement deficiency Abnormal lactate dehydrogenase activity Drusen Papilledema Hepatosplenomegaly Paresthesia Glaucoma Amyloidosis Urticaria Abnormality of complement system Cholestasis Decreased level of thrombomodulin Anuria Hearing impairment Peripheral neuropathy Nephrotic syndrome Polyneuropathy Flexion contracture Growth delay Myalgia Abnormal bleeding Jaundice Abnormality of the kidney Pallor Paralysis Nausea and vomiting Confusion Nausea Increased serum lactate Vomiting Hyperbilirubinemia Personality changes Hyperkalemia Prolonged neonatal jaundice Autoimmune thrombocytopenia Preeclampsia Abnormal renal physiology Neonatal hyperbilirubinemia Arrhythmia Respiratory distress Cough Acne Papule Malabsorption Inflammatory abnormality of the skin Bone pain Increased bone mineral density Cachexia Increased susceptibility to fractures Metaphyseal irregularity Leukocytosis Fatigue Pustule Hypochromic microcytic anemia Synovitis Congenital hypoplastic anemia Abnormality of bone marrow cell morphology Chronic recurrent multifocal osteomyelitis Abnormal inflammatory response Tremor Pulmonary infiltrates Urinary retention Abnormality of blood and blood-forming tissues Recurrent sinusitis Sinusitis Vasculitis Recurrent bacterial infections Recurrent skin infections Chronic kidney disease Nephritis Septic arthritis Otitis media Recurrent streptococcus pneumoniae infections Tonsillitis Recurrent meningococcal disease Recurrent meningitis Glomerular deposits Recurrent Haemophilus influenzae infections Intellectual disability Recurrent otitis media Respiratory tract infection Overgrowth Cataract Asplenia Scarring Recurrent upper respiratory tract infections Abnormal retinal morphology Tubulointerstitial fibrosis Endocapillary hypercellularity Immunodeficiency Arthritis Erythema Autoimmunity Hepatitis Facial erythema Discoid lupus rash Loss of eyelashes Recurrent respiratory infections Lymphadenopathy Nephroblastoma Dysphasia Urethral obstruction Wolff-Parkinson-White syndrome Neurogenic bladder Facial grimacing Urethral stenosis Mild proteinuria Enuresis nocturna Urethral valve Dysuria Encopresis Abnormal facial expression Nocturnal lagophthalmos Cognitive impairment Abnormality of metabolism/homeostasis Hypertriglyceridemia Hyperlipidemia Enuresis Keratoconjunctivitis sicca Gonadal dysgenesis Cryptorchidism Aniridia Neoplasm of the lung Male pseudohermaphroditism Renal neoplasm Hemihypertrophy Neoplasm of the liver Abnormal facial shape Dilatation Hydroureter Constipation Hydronephrosis Vesicoureteral reflux Urinary incontinence Polydipsia Clubbing Polyuria Bloody diarrhea
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