Fever, and Gait disturbance

Diseases related with Fever and Gait disturbance

In the following list you will find some of the most common rare diseases related to Fever and Gait disturbance that can help you solving undiagnosed cases.

Top matches:

Low match BRODY MYOPATHY

Brody myopathy, a disorder of fast-twitch skeletal muscle function, is characterized by exercise-induced impairment of skeletal muscle relaxation, stiffening, and cramps, predominantly in the arms, legs, and eyelids (summary by Odermatt et al., 2000).

Related symptoms:

  • Pain
  • Spasticity
  • Flexion contracture
  • Fever
  • Myopathy


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about BRODY MYOPATHY

Essential tremor may be the most common human movement disorder. The main feature of essential tremor is postural tremor of the arms, but the head, legs, trunk, voice, jaw, and facial muscles also may be involved. Aggravated by emotions, hunger, fatigue, and temperature extremes, the condition may cause a functional disability or even incapacitation. Autosomal dominant inheritance can be demonstrated in most families (summary by Higgins et al., 1997).Deng et al. (2007) provided a detailed review of the genetics of essential tremor. Genetic Heterogeneity of Essential TremorOther forms of hereditary essential tremor include ETM2 (OMIM ), mapped to chromosome 2p25-p22; ETM3 (OMIM ), mapped to chromosome 6p23; ETM4 (OMIM ), caused by mutation in the FUS gene (OMIM ) on chromosome 16p11; and ETM5 (OMIM ), caused by mutation in the TENM4 gene (OMIM ) on chromosome 11q14.

TREMOR, HEREDITARY ESSENTIAL, 1; ETM1 Is also known as fet1|tremor, familial essential, 1

Related symptoms:

  • Hearing impairment
  • Ataxia
  • Cognitive impairment
  • Dysarthria
  • Fever


SOURCES: OMIM MENDELIAN

More info about TREMOR, HEREDITARY ESSENTIAL, 1; ETM1

Acute inflammatory demyelinating polyradiculoneuropathy (AIDP) is an inflammatory neuropathy belonging to the clinical spectrum of Guillain-Barré syndrome (GBS; see this term).

ACUTE INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY Is also known as guillain-barrÉ syndrome, acute inflammatory demyelinating polyradiculoneuropathic form|aidp|acute inflammatory polyneuropathy|acute idiopathic demyelinating polyneuropathy|gbs, acute inflammatory demyelinating polyradiculoneuropathic form

Related symptoms:

  • Generalized hypotonia
  • Hyporeflexia
  • Gait ataxia
  • Unsteady gait
  • Drooling


SOURCES: ORPHANET MENDELIAN

More info about ACUTE INFLAMMATORY DEMYELINATING POLYRADICULONEUROPATHY

Other less relevant matches:

A rare, genetic, neurological disorder characterized by early-onset, progressive ataxia associated with myoclonic seizures (frequently associated with other seizure types such as generalized tonic-clonic, absence and drop attacks), scoliosis of variable severity, areflexia, elevated creatine kinase serum levels, and relative preservation of cognitive function until late in the disease course.

PROGRESSIVE MYOCLONIC EPILEPSY TYPE 6 Is also known as north sea progressive myoclonus epilepsy|pme type 6|gosr2-related progressive myoclonus ataxia|epm6|progressive myoclonus epilepsy type 6

Related symptoms:

  • Seizures
  • Scoliosis
  • Ataxia
  • Peripheral neuropathy
  • Dysarthria


SOURCES: OMIM ORPHANET MENDELIAN

More info about PROGRESSIVE MYOCLONIC EPILEPSY TYPE 6

Low match MALARIA

Malaria is a preventable life-threatening parasitic disease caused by Plasmodium (P. ) parasites that are transmitted by Anophles mosquito bites to humans and is typically clinically characterized by attacks of fever, headache, chills and vomiting.

Related symptoms:

  • Cognitive impairment
  • Anemia
  • Fever
  • Respiratory distress
  • Headache


SOURCES: OMIM ORPHANET MENDELIAN

More info about MALARIA

Recurrent myoglobinuria is characterized by recurrent attacks of rhabdomyolysis associated with muscle pain and weakness and followed by excretion of myoglobin in the urine. Renal failure may occasionally occur. Onset is usually in early childhood under the age of 5 years. Unlike the exercise-induced rhabdomyolyses such as McArdle syndrome (OMIM ), carnitine palmitoyltransferase deficiency (see {255110}), and the Creteil variety of phosphoglycerate kinase deficiency (OMIM ), the attacks in recurrent myoglobinuria no relation to exercise, but are triggered by intercurrent illnesses, commonly upper respiratory tract infections. (Ramesh and Gardner-Medwin, 1992).See {160010} for discussion of a possible autosomal dominant form of myglobinuria.Severe rhabdomyolysis is a major clinical feature of anesthetic-induced malignant hyperthermia (OMIM ), an autosomal dominant disorder.

MYOGLOBINURIA, ACUTE RECURRENT, AUTOSOMAL RECESSIVE Is also known as rhabdomyolysis, acute recurrent|myoglobinuria, familial paroxysmal paralytic

Related symptoms:

  • Muscle weakness
  • Pain
  • Fever
  • Renal insufficiency
  • Areflexia


SOURCES: OMIM MESH MENDELIAN

More info about MYOGLOBINURIA, ACUTE RECURRENT, AUTOSOMAL RECESSIVE

Autosomal dominant intermediate Charcot-Marie-Tooth disease type E is a rare hereditary motor and sensory neuropathy disorder characterized by the typical CMT phenotype (slowly progressive distal muscle weakness and atrophy in upper and lower limbs, distal sensory loss in extremities, reduced or absent deep tendon reflexes and foot deformities) associated with focal segmental glomerulosclerosis (manifesting with proteinuria and progression to end-stage renal disease). Mild or moderate sensorineural hearing loss may also been associated. Nerve biopsy reveals both axonal and demyelinating changes and nerve conduction velocities vary from the demyelinating to axonal range (typically between 25-50m/sec.

AUTOSOMAL DOMINANT INTERMEDIATE CHARCOT-MARIE-TOOTH DISEASE TYPE E Is also known as cmtdie|charcot-marie-tooth disease-nephropathy syndrome|charcot-marie-tooth neuropathy with focal segmental glomerulonephritis

Related symptoms:

  • Hearing impairment
  • Sensorineural hearing impairment
  • Muscle weakness
  • Fever
  • Skeletal muscle atrophy


SOURCES: OMIM ORPHANET MENDELIAN

More info about AUTOSOMAL DOMINANT INTERMEDIATE CHARCOT-MARIE-TOOTH DISEASE TYPE E

Rapid-onset dystonia-parkinsonism (RDP) is a very rare movement disorder, characterized by the abrupt onset of parkinsonism and dystonia, often triggered by physical or psychological stress.

RAPID-ONSET DYSTONIA-PARKINSONISM Is also known as dyt12|dystonia-parkinsonism, rapid-onset|rdp|dystonia 12

Related symptoms:

  • Intellectual disability
  • Seizures
  • Generalized hypotonia
  • Ataxia
  • Motor delay


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about RAPID-ONSET DYSTONIA-PARKINSONISM

This disease is characterised by progressive cerebellar ataxia with pyramidal and spinal cord dysfunction, associated with distinctive MRI anomalies and increased lactate in the abnormal white matter.

LEUKOENCEPHALOPATHY WITH BRAIN STEM AND SPINAL CORD INVOLVEMENT-HIGH LACTATE SYNDROME Is also known as mitochondrial aspartyl-trna synthetase deficiency|leukoencephalopathy with brain stem and spinal cord involvement-lactate elevation syndrome|lbsl

Related symptoms:

  • Intellectual disability
  • Seizures
  • Generalized hypotonia
  • Ataxia
  • Nystagmus


SOURCES: MESH OMIM ORPHANET MENDELIAN

More info about LEUKOENCEPHALOPATHY WITH BRAIN STEM AND SPINAL CORD INVOLVEMENT-HIGH LACTATE SYNDROME

Systemic-onset juvenile idiopathic arthritis is marked by the severity of the extra-articular manifestations (fever, cutaneous eruptions) and by an equal sex ratio.

SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS Is also known as systemic-onset jia|systemic juvenile rheumatoid arthritis|still disease|systemic polyarthritis

Related symptoms:

  • Visual impairment
  • Hepatomegaly
  • Fever
  • Splenomegaly
  • Visual loss


SOURCES: ORPHANET OMIM MENDELIAN

More info about SYSTEMIC-ONSET JUVENILE IDIOPATHIC ARTHRITIS

Top 5 symptoms//phenotypes associated to Fever and Gait disturbance

Symptoms // Phenotype % cases
Ataxia Uncommon - Between 30% and 50% cases
Hyporeflexia Uncommon - Between 30% and 50% cases
Gait ataxia Uncommon - Between 30% and 50% cases
Myalgia Uncommon - Between 30% and 50% cases
Tremor Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Fever and Gait disturbance. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Dysarthria Seizures Unsteady gait Areflexia Progressive cerebellar ataxia Cognitive impairment Generalized hypotonia Muscle weakness

Rare Symptoms - Less than 30% cases

Cerebellar atrophy Falls Intellectual disability Skeletal muscle atrophy Drooling Onion bulb formation Peripheral neuropathy Elevated C-reactive protein level Motor delay Progressive neurologic deterioration Hyperreflexia Clumsiness Acute kidney injury Spasticity Inability to walk Resting tremor Elevated serum creatine phosphokinase Pain Mental deterioration Dystonia Depressivity Flexion contracture Hearing impairment Parkinsonism Abnormality of movement Difficulty walking Anxiety Myoglobinuria Pericarditis Bradykinesia Elevated erythrocyte sedimentation rate Abdominal pain Apraxia Gliosis Broad-based gait Rheumatoid arthritis Torticollis Mutism Neuronal loss in central nervous system Hypertonia Uveitis Postural instability Intellectual disability, mild Emotional lability Dysphagia Joint swelling Juvenile rheumatoid arthritis Anterior uveitis Distal upper limb amyotrophy Mild proteinuria Distal lower limb amyotrophy Axonal loss Focal segmental glomerulosclerosis Steppage gait Hammertoe Dysphonia Torsion dystonia Limb dystonia Glomerulonephritis Splenomegaly Arthralgia Hepatomegaly Visual impairment Sensory ataxia Hepatosplenomegaly Arthritis Episodic ataxia Slurred speech Leukoencephalopathy Truncal ataxia Peripheral axonal neuropathy Poor speech Abnormality of the cerebral white matter Babinski sign Hypomimic face Autoimmunity Skin rash Delayed speech and language development Lymphadenopathy Nystagmus Retrocollis Oculogyric crisis Personality disorder Pleural effusion Craniofacial dystonia Abnormal posturing Weak voice Visual loss Focal dystonia Nephritis Hyperkalemia Glomerulosclerosis Postural tremor Myoclonus Syndactyly Scoliosis Impaired oropharyngeal swallow response Sleepy facial expression Acute demyelinating polyneuropathy Dysesthesia Distal lower limb muscle weakness EMG: neuropathic changes Episodic fever Kinetic tremor Head tremor Hand tremor Personality changes Abnormality of extrapyramidal motor function Febrile seizures Memory impairment Migraine Rigidity Hypoglycemia Dementia Cerebral atrophy Fatigue Myotonia Spastic paraparesis Paraparesis Muscle stiffness Muscle cramps Myopathy Sensory neuropathy Cutaneous photosensitivity Foot dorsiflexor weakness Rhabdomyolysis Frequent falls Split hand Sensory impairment Distal sensory impairment Distal amyotrophy Stage 5 chronic kidney disease Distal muscle weakness Proteinuria Pes cavus Sensorineural hearing impairment Acute rhabdomyolysis Recurrent myoglobinuria Dark urine Malignant hyperthermia Recurrent upper respiratory tract infections Absence seizures Retinopathy Atonic seizures Motor deterioration Anemia Respiratory distress Headache Thrombocytopenia Nausea and vomiting Generalized muscle weakness Hyperbilirubinemia Abnormality of blood and blood-forming tissues Reduced consciousness/confusion Gait imbalance Morphological abnormality of the central nervous system Renal insufficiency Serositis


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