Edema, and Psoriasiform dermatitis

Diseases related with Edema and Psoriasiform dermatitis

In the following list you will find some of the most common rare diseases related to Edema and Psoriasiform dermatitis that can help you solving undiagnosed cases.

Top matches:

Peeling skin syndrome is a rare genodermatosis with variable age of onset from birth to adulthood. Clinically, it is characterized by a pruritic or nonpruritic spontaneous superficial peeling of the skin, which sometimes is accompanied by erythema or vesiculation. The skin involvement is usually general, but in some patients the scalp, face, palms, and soles may be unaffected. Seasonal changes have been reported. The histologic picture is characterized by separation of the epidermis between the statum corneum and the stratum granulosum (summary by Hacham-Zadeh and Holubar, 1985).Generalized PSS has been subclassified into a noninflammatory type, designated type A, and an inflammatory type, designated type B (Traupe, 1989; Judge et al., 2004). Type B, in which generalized peeling skin is associated with pruritus and atopy, is characterized by lifelong patchy peeling of the entire skin with onset at birth or shortly thereafter. Several patients have been reported with high IgE levels (summary by Oji et al., 2010). Type A, a continuous nonerythematous exfoliation, is usually congenital or appears during childhood (summary by Mallet et al., 2013). Genetic Heterogeneity of Peeling Skin SyndromePeeling skin syndrome-2 (PSS2 ), an acral form of the disorder that mainly involves palmar and plantar skin, is caused by mutation in the TGM5 gene (OMIM ) on chromosome 15q15. Peeling skin syndrome-3 (PSS3 ) is caused by mutation in the CHST8 gene (OMIM ) on chromosome 19q13. Peeling skin syndrome-4 (PSS4 ) is caused by mutation in the CSTA gene (OMIM ) on chromosome 3q21. Peeling skin syndrome-5 (PSS5 ) is caused by mutation in the SERPINB8 gene (OMIM ) on chromosome 18q22. PSS6 (OMIM ) is caused by mutation in the FLG2 gene (OMIM ) on chromosome 1q21.

PEELING SKIN SYNDROME 1; PSS1 Is also known as pss|keratolysis exfoliativa congenita|deciduous skin|skin peeling, familial continuous generalized

Related symptoms:

  • Short stature
  • Edema
  • Abnormality of metabolism/homeostasis
  • Alopecia
  • Hyperkeratosis


SOURCES: OMIM MENDELIAN

More info about PEELING SKIN SYNDROME 1; PSS1

Classical mycosis fungoides is the most common type of mycosis fungoides (MF; see this term), a form of cutaneous T-cell lymphoma, and is characterized by slow progression from patches to more infiltrated plaques and eventually to tumors.

CLASSIC MYCOSIS FUNGOIDES Is also known as mycosis fungoides, alibert-bazin type

Related symptoms:

  • Hepatomegaly
  • Edema
  • Splenomegaly
  • Alopecia
  • Hyperkeratosis


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about CLASSIC MYCOSIS FUNGOIDES

Sterile multifocal osteomyelitis with periostitis and pustulosis is a rare, severe, genetic autoinflammatory syndrome characterized by usually neonatal onset of generalized neutrophilic cutaneous pustulosis and severe, recurrent, multifocal, aseptic osteomyelitis with marked periostitis, typically affecting distal ribs, long bones and vertebral bodies. High levels of acute-phase reactants (with no fever associated) and onychosis are frequently observed additional features.

STERILE MULTIFOCAL OSTEOMYELITIS WITH PERIOSTITIS AND PUSTULOSIS Is also known as interleukin-1 receptor antagonist deficiency|interleukin 1 receptor antagonist deficiency|autoinflammatory disease due to interleukin-1 receptor antagonist deficiency|dira|ompp

Related symptoms:

  • Pain
  • Feeding difficulties
  • Hepatomegaly
  • Fever
  • Respiratory insufficiency


SOURCES: ORPHANET OMIM MENDELIAN

More info about STERILE MULTIFOCAL OSTEOMYELITIS WITH PERIOSTITIS AND PUSTULOSIS

Other less relevant matches:

Medium match NETHERTON SYNDROME

Netherton syndrome (NS) is a skin disorder characterized by congenital ichthyosiform erythroderma (CIE), a distinctive hair shaft defect (trichorrhexis invaginata; TI) and atopic manifestations.

NETHERTON SYNDROME Is also known as erythroderma, ichthyosiform, with hypotrichosis and hyper-ige|comÈl-netherton syndrome|bamboo hair syndrome|comel-netherton syndrome|ns|netherton disease

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Growth delay


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about NETHERTON SYNDROME

Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by melanocytic macules of the lips, buccal mucosa, and digits; multiple gastrointestinal hamartomatous polyps; and an increased risk of various neoplasms.

PEUTZ-JEGHERS SYNDROME; PJS Is also known as polyps-and-spots syndrome|polyposis, hamartomatous intestinal

Related symptoms:

  • Neoplasm
  • Hypertension
  • Edema
  • Diarrhea
  • Headache


SOURCES: OMIM MENDELIAN

More info about PEUTZ-JEGHERS SYNDROME; PJS

Medium match PROLIDASE DEFICIENCY

Prolidase deficiency is an inherited disorder of peptide metabolism characterized by severe skin lesions, recurrent infections (involving mainly the skin and respiratory system), dysmorphic facial features, variable cognitive impairment, and splenomegaly.

PROLIDASE DEFICIENCY Is also known as hyperimidodipeptiduria

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Hearing impairment
  • Hypertelorism
  • Micrognathia


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about PROLIDASE DEFICIENCY

Low match H SYNDROME

H syndrome is a systemic inherited histiocytosis, with characteristic cutaneous findings accompanying systemic manifestations. H syndrome refers to the major clinical findings of hyperpigmentation, hypertrichosis, hepatosplenomegaly, heart anomalies, hearing loss, hypogonadism, low height, and occasionally, hyperglycemia/diabetes mellitus. Due to overlapping clinical features, H syndrome is now considered to include pigmented hypertrichosis with insulin dependent diabetes mellitus syndrome (PHID), Faisalabad histiocytosis (FHC) and familial sinus histiocytosis with massive lymphadenopathy (FSHML).

H SYNDROME Is also known as sinus histiocytosis and massive lymphadenopathy|hjcd|shml|hyperpigmentation, cutaneous, with hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism with or without hearing loss|h syndrome|faisalabad histiocytosis|pigmented hypertrichosis wi

Related symptoms:

  • Global developmental delay
  • Short stature
  • Generalized hypotonia
  • Hearing impairment
  • Growth delay


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about H SYNDROME

Buruli ulcer is an infectious disease prevalent in many tropical and subtropical regions caused by infection with Mycobacterium ulcerans. It is the third most frequent mycobacterial disease in humans worldwide, after tuberculosis (OMIM ) and leprosy (OMIM ). Lesions are most common on exposed parts of the body, especially the limbs. Buruli ulcer derives its name from a county in Uganda, East Africa, north of Kampala, where the disease was found in the late 1950s in hundreds of people living near marshes and riverine areas near the Nile River (Clancey et al., 1961; Barker, 1971). The disease was first described in the medical literature in 1948 in a report on patients in Australia (MacCallum et al., 1948). Patients have also been reported from tropical areas in Latin America and Asia (Stienstra et al., 2006; van der Werf et al., 2005).

BURULI ULCER, SUSCEPTIBILITY TO Is also known as mycobacterium ulcerans, susceptibility to

Related symptoms:

  • Edema


SOURCES: OMIM MENDELIAN

More info about BURULI ULCER, SUSCEPTIBILITY TO

PUSTULOSIS PALMARIS ET PLANTARIS Is also known as localized pustular psoriasis|lpp|ppp|palmoplantar pustulosis

Related symptoms:

  • Pain
  • Pruritus
  • Psoriasiform dermatitis
  • Pustule


SOURCES: ORPHANET MENDELIAN

More info about PUSTULOSIS PALMARIS ET PLANTARIS

Top 5 symptoms//phenotypes associated to Edema and Psoriasiform dermatitis

Symptoms // Phenotype % cases
Skin rash Uncommon - Between 30% and 50% cases
Hyperkeratosis Uncommon - Between 30% and 50% cases
Pruritus Uncommon - Between 30% and 50% cases
Inflammatory abnormality of the skin Uncommon - Between 30% and 50% cases
Alopecia Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Edema and Psoriasiform dermatitis. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Splenomegaly Hepatomegaly Short stature Fever Dry skin Global developmental delay Scaling skin Erythroderma Erythema Epidermal acanthosis Ichthyosis Asthma

Rare Symptoms - Less than 30% cases

Recurrent respiratory infections Sepsis Ptosis Pain Abnormality of the kidney Hypertelorism Hearing impairment Increased antibody level in blood Gynecomastia Diarrhea Recurrent infections Osteolysis Leukocytosis Osteomyelitis Pustule Intellectual disability Dehydration Growth delay Irregular hyperpigmentation Failure to thrive Malabsorption Anemia Elevated erythrocyte sedimentation rate Hypotrichosis Eczema Proptosis Angioedema Palmoplantar keratoderma Fine hair Lymphadenopathy Intellectual disability, mild Increased IgE level Skin ulcer Abnormality of metabolism/homeostasis Congenital ichthyosiform erythroderma Hepatosplenomegaly Urticaria Brittle hair Frontal bossing Anteverted nares Ventricular septal defect Ventriculomegaly Low anterior hairline Wide nasal bridge Brachydactyly Atrial septal defect Hyperreflexia Convex nasal ridge Hydrocephalus Pneumonia Hernia Micropenis Camptodactyly Low-set, posteriorly rotated ears Conductive hearing impairment Pes planus Dyspnea Hypothyroidism Diabetes mellitus Clinodactyly Hypogonadism Posteriorly rotated ears Severe short stature Delayed skeletal maturation Abnormal heart morphology Patent ductus arteriosus Epicanthus Hepatitis Flexion contracture Aplasia/Hypoplasia of the skin Recurrent pneumonia Generalized hirsutism Abnormality of the fingernails Lymphedema Abnormality of retinal pigmentation Reduced bone mineral density Systemic lupus erythematosus Abnormal lung morphology Petechiae Thin skin Abnormality of the hip bone Depressed nasal ridge Cutaneous photosensitivity Abnormality of the immune system Sensorineural hearing impairment Prolonged neonatal jaundice Hypoplasia of the zygomatic bone Low posterior hairline Chronic lung disease Concave nasal ridge White forelock Abnormality of the middle ear Poliosis Facial hirsutism Crusting erythematous dermatitis Diffuse telangiectasia Recurrent cystitis Generalized hypotonia Bilateral single transverse palmar creases Apnea Hypertrichosis Abnormal cardiac septum morphology Varicose veins Histiocytosis Skin nodule Nasal obstruction Recurrent pharyngitis Decreased serum testosterone level Communicating hydrocephalus Aspiration pneumonia Chronic rhinitis Abnormal eyebrow morphology Enlarged kidney Exocrine pancreatic insufficiency Severe sensorineural hearing impairment Episodic fever Polycythemia Scleroderma Reticulocytopenia Abnormality of cardiovascular system physiology Microcytic anemia Snoring Seborrheic keratosis Retroperitoneal fibrosis Upper eyelid edema Bilateral camptodactyly Cervical lymphadenopathy Stiff skin Episcleritis Pancreatic hypoplasia Panniculitis Facial telangiectasia Myelofibrosis Generalized lymphadenopathy Corneal arcus Hyperplasia of the maxilla Broad finger Lipoatrophy Hallux valgus Retinopathy Growth hormone deficiency Bilateral sensorineural hearing impairment Mitral valve prolapse Overgrowth Amenorrhea Decreased testicular size Wide intermamillary distance Full cheeks Epistaxis Recurrent fractures Polyneuropathy Flat face Cleft upper lip Abnormality of the foot Delayed puberty Pectus carinatum Cardiomegaly Blue sclerae Hyperglycemia Elbow flexion contracture Stridor Lipodystrophy Sleep apnea Azoospermia Plagiocephaly Type I diabetes mellitus Hypergonadotropic hypogonadism Hypertriglyceridemia Aspiration Hyperpigmentation of the skin Gingival overgrowth Telangiectasia Bronchiectasis Primary amenorrhea Arachnodactyly Hirsutism Endolymphatic sac tumor Genu valgum Acanthosis nigricans Low-grade fever Cerebral vasculitis Periostitis Chronic recurrent multifocal osteomyelitis Onychomadesis Seizures Weight loss Hydronephrosis Decreased antibody level in blood Sparse scalp hair Sparse and thin eyebrow Abnormality of the hair Aminoaciduria Sparse eyelashes Abnormal intestine morphology Fused cervical vertebrae Hypothermia Allergic rhinitis Trichorrhexis nodosa Congenital nonbullous ichthyosiform erythroderma Allergy Verrucae Villous atrophy Severe postnatal growth retardation Recurrent skin infections Atopic dermatitis Abnormality of the musculature Ectopic kidney Malnutrition Emphysema Intracranial hemorrhage Fetal distress Stomatitis Hypernatremia Abnormality of hair texture Abnormal eyelid morphology Hypopigmented skin patches Neoplasm of the skin Abnormality of the nail Lymphoma Orthokeratotic hyperkeratosis Concave nail Abnormality of bone marrow cell morphology Hypergranulosis Onycholysis Dystrophic fingernails Parakeratosis Ectropion Abnormal blistering of the skin Poikiloderma T-cell lymphoma Thrombocytosis Meningitis Joint swelling Fragile skin Vertebral fusion Interstitial pulmonary abnormality Hyperostosis Vasculitis Arthralgia Skin plaque Osteopenia Respiratory distress Respiratory insufficiency Feeding difficulties Cutaneous T-cell lymphoma Abnormal lymphocyte morphology Immunologic hypersensitivity Hypernatremic dehydration Carious teeth Intestinal polyp Congenital shortened small intestine Thyroid nodule Uterine neoplasm Gastrointestinal carcinoma Clear cell renal cell carcinoma Intussusception Testicular neoplasm Micrognathia Bloody diarrhea Thrombophlebitis Hematemesis Intestinal bleeding Hamartomatous polyposis Neoplasm of the breast Precocious puberty with Sertoli cell tumor Abnormal facial shape Rectal prolapse Malar flattening Papule Elevated hepatic transaminase High forehead Prominent forehead Obesity Thrombocytopenia Short nose High palate Vomiting Intellectual disability, severe Downslanted palpebral fissures Depressed nasal bridge Visual impairment Delayed speech and language development Nasal polyposis Biliary tract abnormality Brittle scalp hair Carcinoma Growth abnormality Breast carcinoma Hemangioma Accelerated skeletal maturation Nevus Abdominal distention Abdominal pain Melanocytic nevus Hyperhidrosis Dilatation Headache Hypertension Neoplasm IgE-mediated food allergy Polycystic kidney dysplasia Clubbing Pancreatic cysts Vitiligo Intestinal polyposis Ovarian cyst Multiple myeloma Clubbing of fingers Neoplasm of the pancreas Abnormality of the mouth Renal cell carcinoma Intestinal obstruction Abnormality of the ureter Iron deficiency anemia Ovarian neoplasm Hamartoma Macule Hypermelanotic macule Nail dystrophy


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