Edema, and Burkitt lymphoma

Diseases related with Edema and Burkitt lymphoma

In the following list you will find some of the most common rare diseases related to Edema and Burkitt lymphoma that can help you solving undiagnosed cases.

Top matches:

Medium match EWING SARCOMA

Ewing's sarcoma is a malignant small round cell bone tumor with strong metastatic potential.

Related symptoms:

  • Neoplasm
  • Pain
  • Anemia
  • Fever
  • Weight loss


SOURCES: OMIM ORPHANET MENDELIAN

More info about EWING SARCOMA

Follicular lymphoma is a form of non-Hodgkin lymphoma (see this term) characterized by a proliferation of B cells whose nodular structure of follicular architecture is preserved.

FOLLICULAR LYMPHOMA Is also known as oncogene b-cell leukemia 2

Related symptoms:

  • Neoplasm
  • Fever
  • Fatigue
  • Diarrhea
  • Splenomegaly


SOURCES: OMIM ORPHANET MENDELIAN

More info about FOLLICULAR LYMPHOMA

Classical mycosis fungoides is the most common type of mycosis fungoides (MF; see this term), a form of cutaneous T-cell lymphoma, and is characterized by slow progression from patches to more infiltrated plaques and eventually to tumors.

CLASSIC MYCOSIS FUNGOIDES Is also known as mycosis fungoides, alibert-bazin type

Related symptoms:

  • Hepatomegaly
  • Edema
  • Splenomegaly
  • Alopecia
  • Hyperkeratosis


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about CLASSIC MYCOSIS FUNGOIDES

Other less relevant matches:

Sézary syndrome (SS) is an aggressive form of cutaneous T-cell lymphoma characterized by a triad of erythroderma, lymphadenopathy and circulating atypical lymphocytes (Sézary cells).

SÉZARY SYNDROME Is also known as sÉzary lymphoma

Related symptoms:

  • Neoplasm
  • Abnormal facial shape
  • Peripheral neuropathy
  • Hepatomegaly
  • Fever


SOURCES: MESH ORPHANET MENDELIAN

More info about SÉZARY SYNDROME

Zur Stadt et al. (2005) summarized the clinical features of hemophagocytic lymphohistiocytosis (HLH), a rare autosomal recessive disorder characterized by massive infiltration of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, and less frequently central nervous system involvement. In FHL, the familial form of the disease, first episodes occur mostly during infancy, with a rapidly fatal outcome if untreated. Diagnostic criteria also include low fibrinogen and high triglyceride and ferritin levels. Chemoimmunotherapy based on corticosteroids, epipodophyllotoxins, and cyclosporin succeeds in controlling the disease in the majority of patients, although remission is rarely obtained (Henter et al., 2002). Most patients suffer an early death unless they are treated by hematopoietic stem cell transplantation (Durken et al., 1999). Genetic Heterogeneity of Familial Hemophagocytic LymphohistiocytosisFamilial hemophagocytic lymphohistiocytosis exhibits genetic heterogeneity. In some families, familial hemophagocytic lymphohistiocytosis has been found to be linked to chromosome 9q (HPLH1, FHL1). FHL2 (OMIM ) is caused by mutation in the PRF1 gene (OMIM ) on chromosome 10q22; FHL3 (OMIM ) is caused by mutation in the UNC13D gene (OMIM ) on chromosome 17q25; FHL4 (OMIM ) is caused by mutation in the syntaxin-11 gene (STX11 ) on chromosome 6q24; and FHL5 (OMIM ) is caused by mutation in the syntaxin-binding protein-2 (STXBP2 ), which is an interaction partner of STX11, on chromosome 19p13.Furthermore, before the identification of mutations in the RAG1 (OMIM ) and RAG2 (OMIM ) genes, both of which map to 11p, Omenn syndrome (familial reticuloendotheliosis with eosinophilia; {603554}) was not thought to be clearly distinct from other reported cases of hemophagocytic lymphohistiocytosis.

HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 1; FHL1 Is also known as hemophagocytic reticulosis, familial|hlh1|hemophagocytic lymphohistiocytosis, familial|erythrophagocytic lymphohistiocytosis, familial|reticulosis, familial histiocytic|hplh1|fhl|fhlh|hplh|fel

Related symptoms:

  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Ataxia
  • Neoplasm


SOURCES: OMIM MENDELIAN

More info about HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 1; FHL1

Lymphoproliferative syndrome-1 is an autosomal recessive primary immunodeficiency characterized by onset in early childhood of Epstein-Barr virus (EBV)-associated immune dysregulation, manifest as lymphoma, lymphomatoid granulomatosis, hemophagocytic lymphohistiocytosis, Hodgkin disease, and/or hypogammaglobulinemia. Autoimmune disorders, such as autoimmune hemolytic anemia or renal disease, may also occur. Patients show a high EBV viral load and decreased invariant natural killer T cells. It is unknown whether patients with ITK mutations are intrinsically susceptible to development of lymphoma or dysgammaglobulinemia in the absence of EBV infection (summary by Stepensky et al., 2011; Linka et al., 2012).For a discussion of genetic heterogeneity of lymphoproliferative syndrome, see XLP1 (OMIM ).

Related symptoms:

  • Anemia
  • Hepatomegaly
  • Fever
  • Splenomegaly
  • Immunodeficiency


SOURCES: OMIM MESH MENDELIAN

More info about LYMPHOPROLIFERATIVE SYNDROME 1; LPFS1

Buruli ulcer is an infectious disease prevalent in many tropical and subtropical regions caused by infection with Mycobacterium ulcerans. It is the third most frequent mycobacterial disease in humans worldwide, after tuberculosis (OMIM ) and leprosy (OMIM ). Lesions are most common on exposed parts of the body, especially the limbs. Buruli ulcer derives its name from a county in Uganda, East Africa, north of Kampala, where the disease was found in the late 1950s in hundreds of people living near marshes and riverine areas near the Nile River (Clancey et al., 1961; Barker, 1971). The disease was first described in the medical literature in 1948 in a report on patients in Australia (MacCallum et al., 1948). Patients have also been reported from tropical areas in Latin America and Asia (Stienstra et al., 2006; van der Werf et al., 2005).

BURULI ULCER, SUSCEPTIBILITY TO Is also known as mycobacterium ulcerans, susceptibility to

Related symptoms:

  • Edema


SOURCES: OMIM MENDELIAN

More info about BURULI ULCER, SUSCEPTIBILITY TO

Low match KAPOSI SARCOMA

Kaposi sarcoma (KS) is a rare human herpes virus 8 (HHV-8)-induced endothelial inflammatory neoplasm that develops is various clinically distinct settings, manifesting mostly as cutaneous lesions, or mucosal or visceral involvement.

KAPOSI SARCOMA Is also known as multiple idiopathic pigmented hemangiosarcoma, susceptibility to

Related symptoms:

  • Neoplasm
  • Hypertension
  • Fever
  • Fatigue
  • Edema


SOURCES: OMIM ORPHANET MENDELIAN

More info about KAPOSI SARCOMA

Autoimmune lymphoproliferative syndrome (ALPS) is a rare, inherited disorder characterized by non-malignant lymphoproliferation, multilineage cytopenias, and a lifelong increased risk of Hodgkin's and non-Hodgkin's lymphoma.

AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME Is also known as alps|autoimmune lymphoproliferative syndrome, type i, autosomal dominant|fas deficiency|canale-smith syndrome

Related symptoms:

  • Neoplasm
  • Anemia
  • Hepatomegaly
  • Edema
  • Splenomegaly


SOURCES: OMIM ORPHANET MENDELIAN

More info about AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME

Low match OMENN SYNDROME

Omenn syndrome (OS) is an inflammatory condition characterized by erythroderma, desquamation, alopecia, chronic diarrhea, failure to thrive, lymphadenopathy, and hepatosplenomegaly, associated with severe combined immunodeficiency (SCID; see this term).

OMENN SYNDROME Is also known as combined immunodeficiency with hypereosinophilia|reticuloendotheliosis, familial, with eosinophilia|severe combined immunodeficiency with hypereosinophilia

Related symptoms:

  • Failure to thrive
  • Anemia
  • Hepatomegaly
  • Fever
  • Edema


SOURCES: ORPHANET OMIM MENDELIAN

More info about OMENN SYNDROME

Top 5 symptoms//phenotypes associated to Edema and Burkitt lymphoma

Symptoms // Phenotype % cases
Lymphoma Very Common - Between 80% and 100% cases
Lymphadenopathy Common - Between 50% and 80% cases
Fever Common - Between 50% and 80% cases
Splenomegaly Common - Between 50% and 80% cases
Hepatomegaly Common - Between 50% and 80% cases

Other less frequent symptoms

Patients with Edema and Burkitt lymphoma. may also develop some of the following symptoms:

Common Symptoms - More than 50% cases

Neoplasm

Uncommon Symptoms - Between 30% and 50% cases

Anemia Hepatosplenomegaly Skin rash Immunodeficiency Leukemia Thrombocytopenia Weight loss Generalized lymphadenopathy Hemolytic anemia Alopecia Eosinophilia Abnormal lymphocyte morphology Pruritus Hypotrichosis Dry skin T-cell lymphoma Erythroderma Neoplasm of the skin Cellular immunodeficiency Pleural effusion Autoimmunity Pneumonia Diarrhea

Rare Symptoms - Less than 30% cases

Papule Irregular hyperpigmentation Lymphoproliferative disorder Skin plaque Hodgkin lymphoma Autoimmune hemolytic anemia Cutaneous T-cell lymphoma Hemophagocytosis Histiocytosis Generalized edema Hypoproteinemia Thickened skin Failure to thrive Recurrent infections Pulmonary infiltrates Encephalopathy Abnormality of the liver Severe combined immunodeficiency Increased antibody level in blood Pancytopenia Purpura Sepsis Combined immunodeficiency Fatigue Leukocytosis Lymphedema Sarcoma Skin nodule Meningitis Chronic lymphatic leukemia Psoriasiform dermatitis Hepatitis Susceptibility to herpesvirus Neoplasm by anatomical site Renal insufficiency Carcinoma Glomerulonephritis Vasculitis Urticaria Abnormality of the spleen Petechiae Basal cell carcinoma Iron deficiency anemia Autoimmune thrombocytopenia Uveitis Hepatocellular carcinoma Venous insufficiency Macule Abnormality of the lower limb Paraplegia Elevated erythrocyte sedimentation rate Pericardial effusion Myeloid leukemia IgG deficiency Immune dysregulation Stomatitis Recurrent aphthous stomatitis Granulomatosis Dysgammaglobulinemia Abnormality of the gastrointestinal tract Hypertension Paralysis Gastrointestinal hemorrhage Pulmonary arterial hypertension Abnormal lung morphology Hemangioma Hypermelanotic macule Abnormal retinal morphology Multiple myeloma Antinuclear antibody positivity Chronic noninfectious lymphadenopathy Extramedullary hematopoiesis Aplasia/Hypoplasia of the eyebrow Abnormality of the metaphysis Chronic diarrhea Short toe Increased body weight Recurrent bacterial infections Shock Disproportionate short-limb short stature Scaling skin Thyroiditis Nephrotic syndrome Hashimoto thyroiditis Recurrent viral infections Hypoplasia of the thymus Metaphyseal chondrodysplasia B lymphocytopenia Recurrent fungal infections Protracted diarrhea Desquamation of skin soon after birth Inflammatory abnormality of the skin Hypothyroidism Lymphocytosis Cervical lymphadenopathy Decreased antibody level in blood Increased IgA level Antiphospholipid antibody positivity Follicular hyperplasia Increased IgM level Autoimmune neutropenia Reduced delayed hypersensitivity Increased IgG level Rheumatoid factor positive Severe short stature Coombs-positive hemolytic anemia Platelet antibody positive Decreased lymphocyte apoptosis Antineutrophil antibody positivity Smooth muscle antibody positivity Elevated proportion of CD4-negative, CD8-negative, alpha-beta regulatory T cells Increased proportion of HLA DR+ T cells Intermediate uveitis Lymphopenia Acute lymphoblastic leukemia Ascites B-cell lymphoma Seizures Global developmental delay Generalized hypotonia Ataxia Night sweats Muscular hypotonia Hypertonia Glucose intolerance Lichenification Jaundice Elevated hepatic transaminase Abnormality of the nervous system Irritability Confusion Hepatic failure Coma Tetraplegia Abnormal immunoglobulin level Abnormality of the pleura Gliosis Abnormal facial shape Abnormality of the nail Abnormal eyelid morphology Poikiloderma Abnormality of bone marrow cell morphology Skin ulcer Eczema Erythema Hyperkeratosis Peripheral neuropathy Gangrene Skeletal muscle atrophy Tremor Abnormality of the peritoneum Mediastinal lymphadenopathy Nail dystrophy Palmoplantar keratoderma Abnormality of the face Ectropion Insulin resistance Peripheral demyelination Neuroblastoma Increased total bilirubin Primitive neuroectodermal tumor Decreased HDL cholesterol concentration Prolonged prothrombin time Chronic myelogenous leukemia Meningioma Increased LDL cholesterol concentration Partial albinism Granulocytopenia Ewing sarcoma Increased VLDL cholesterol concentration Hypofibrinogenemia CSF pleocytosis Polyneuritis Plasmacytosis Lipogranulomatosis Abnormal natural killer cell physiology Hypopigmented skin patches Prolonged partial thromboplastin time Acute leukemia Neutropenia Hypoalbuminemia Hypertriglyceridemia Aspiration Hyperbilirubinemia Nausea Leukopenia Increased intracranial pressure Respiratory tract infection Encephalitis Hemiplegia Increased serum ferritin Hyponatremia Albinism Abnormality of the coagulation cascade Pain Episodic fever Neoplasm of the peripheral nervous system Peripheral neuroepithelioma Increased CSF protein Severe B lymphocytopenia


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