Congestive heart failure, and Gynecomastia

Diseases related with Congestive heart failure and Gynecomastia

In the following list you will find some of the most common rare diseases related to Congestive heart failure and Gynecomastia that can help you solving undiagnosed cases.


Top matches:

High match SYMPTOMATIC FORM OF HEMOCHROMATOSIS TYPE 1


Symptomatic form of hemochromatosis type 1 is a rare, hereditary hemochromatosis characterized by inappropriately regulated intestinal iron absorption which leads to excessive iron storage in various organs and manifests with a wide range of signs and symptoms, including abdominal pain, weakness, lethargy, weight loss, elevated serum aminotransferase levels, increase in skin pigmentation, and/or arthropathy in the metacarpophalangeal joints. Other commonly associated manifestations include hepatomegaly, cirrhosis, liver fibrosis, hepatocellular carcinoma, restrictive cardiomyopathy and/or diabetes mellitus.

SYMPTOMATIC FORM OF HEMOCHROMATOSIS TYPE 1 Is also known as symptomatic form of hfe-related hereditary hemochromatosis|symptomatic form of classic hemochromatosis

Related symptoms:

  • Peripheral neuropathy
  • Hepatomegaly
  • Fatigue
  • Cardiomyopathy
  • Congestive heart failure


SOURCES: ORPHANET MENDELIAN

More info about SYMPTOMATIC FORM OF HEMOCHROMATOSIS TYPE 1

High match TSH-SECRETING PITUITARY ADENOMA


A rare adenoma of the anterior lobe of the pituitary gland that produces thyrotropin. It is usually associated with goiter and hyperthyroidism.

TSH-SECRETING PITUITARY ADENOMA Is also known as thyrotroph adenoma|pituitary thyrotrophic adenoma|thyroid stimulating hormone-secreting pituitary adenoma|tsh-oma

Related symptoms:

  • Seizures
  • Ptosis
  • Hypertension
  • Tremor
  • Fatigue


SOURCES: ORPHANET MENDELIAN

More info about TSH-SECRETING PITUITARY ADENOMA

High match CARNEY COMPLEX, TYPE 1; CNC1


Carney complex is an autosomal dominant multiple neoplasia syndrome characterized by cardiac, endocrine, cutaneous, and neural myxomatous tumors, as well as a variety of pigmented lesions of the skin and mucosae. Carney complex may simultaneously involve multiple endocrine glands, similar to classic MEN syndromes (MEN1; {131100} and MEN2; {171400}). Carney complex shows some similarities to McCune-Albright syndrome (MAS ), a sporadic condition that is also characterized by multiple endocrine and nonendocrine tumors, and shares skin abnormalities and some nonendocrine tumors with the lentiginoses and certain of the hamartomatoses, particularly Peutz-Jeghers syndrome (PJS ). Carney complex is often associated with the unusual large-cell calcifying Sertoli cell tumor and psammomatous melanotic schwannomas (Kirschner et al., 2000; Stratakis et al., 2001).

CARNEY COMPLEX, TYPE 1; CNC1 Is also known as lamb syndrome|myxoma, spotty pigmentation, and endocrine overactivity|carney myxoma-endocrine complex|car|carney syndrome|name syndrome

Related symptoms:

  • Neoplasm
  • Muscle weakness
  • Pain
  • Hypertension
  • Fever


SOURCES: OMIM MENDELIAN

More info about CARNEY COMPLEX, TYPE 1; CNC1

Mendelian

Too many results?
We can help you with your rare disease diagnosis.

Learn more

Other less relevant matches:

High match MCCUNE-ALBRIGHT SYNDROME; MAS


Activating or gain-of-function GNAS1 mutations in patients with the McCune-Albright syndrome are present in the mosaic state, resulting from a postzygotic somatic mutation appearing early in the course of development which yields a monoclonal population of mutated cells within variously affected tissues. The nonmosaic state for most activating mutations is presumably lethal to the embryo. The disorder is characterized clinically by the classic triad of polyostotic fibrous dysplasia (POFD), cafe-au-lait skin pigmentation, and peripheral precocious puberty. However, the disorder is clinically heterogeneous and can include various other endocrinologic anomalies such as thyrotoxicosis, pituitary gigantism, and Cushing syndrome (OMIM ) (Lumbroso et al., 2004).

MCCUNE-ALBRIGHT SYNDROME; MAS Is also known as albright syndrome

Related symptoms:

  • Hearing impairment
  • Neoplasm
  • Abnormal facial shape
  • Depressed nasal bridge
  • Blindness


SOURCES: ORPHANET OMIM MENDELIAN

More info about MCCUNE-ALBRIGHT SYNDROME; MAS

High match FRANK-TER HAAR SYNDROME


Frank-ter Haar syndrome (formerly considered as an autosomal recessive form of Melnick-Needles syndrome; see this term) is defined by megalocornea, multiple skeletal anomalies, characteristic facial dysmorphism (wide fontanels, prominent forehead, hypertelorism, prominent eyes, full cheeks and micrognathia) and developmental delay.

FRANK-TER HAAR SYNDROME Is also known as ter haar syndrome|borrone dermatocardioskeletal syndrome|melnick-needles syndrome, autosomal recessive, formerly

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Scoliosis
  • Growth delay


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about FRANK-TER HAAR SYNDROME

Medium match ALSTRÖM SYNDROME


Alström syndrome (AS) is a multisystemic disorder characterized by cone-rod dystrophy, hearing loss, obesity, insulin resistance and hyperinsulinemia, type 2 diabetes mellitus, dilated cardiomyopathy (DCM; see this term), and progressive hepatic and renal dysfunction.

ALSTRÖM SYNDROME Is also known as alss

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Hearing impairment


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about ALSTRÖM SYNDROME

Low match SEGMENTAL OUTGROWTH-LIPOMATOSIS-ARTERIOVENOUS MALFORMATION-EPIDERMAL NEVUS SYNDROME


Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome is a rare, genetic, polymalformative syndrome characterized by progressive, proportionate, asymmetric segmental overgrowth (with soft tissue hypertrophy and ballooning effect) that develops and progresses rapidly in early childhood, arteriovenous and lymphatic vascular malformations, lipomatosis and linear epidermal nevus (arranged in whorls along the lines of Blaschko). Clinical symptoms of Cowden syndrome, such as macrocephaly and progressive development of numerous hypertrophic hamartomatous and neoplastic lesions involving multiple organs and systems, are also associated. Patients present an increased risk of developing cancer.

SEGMENTAL OUTGROWTH-LIPOMATOSIS-ARTERIOVENOUS MALFORMATION-EPIDERMAL NEVUS SYNDROME Is also known as solamen syndrome

Related symptoms:

  • Macrocephaly
  • Congestive heart failure
  • Papule
  • Talipes
  • Recurrent fractures


SOURCES: ORPHANET MENDELIAN

More info about SEGMENTAL OUTGROWTH-LIPOMATOSIS-ARTERIOVENOUS MALFORMATION-EPIDERMAL NEVUS SYNDROME

Low match CARNEY COMPLEX


Carney complex (CNC) is characterized by spotty skin pigmentation, endocrine overactivity and myxomas.

CARNEY COMPLEX Is also known as myxoma-spotty pigmentation-endocrine overactivity syndrome|carney syndrome|carney myxoma-endocrine complex, type 2

Related symptoms:

  • Neoplasm
  • Congestive heart failure
  • Stroke
  • Hirsutism
  • Sudden cardiac death


SOURCES: ORPHANET OMIM MENDELIAN

More info about CARNEY COMPLEX

Low match CHAR SYNDROME


Char syndrome is characterized by the triad of patent ductus arteriosus (PDA), facial dysmorphism and hand anomalies.

CHAR SYNDROME Is also known as patent ductus arteriosus with facial dysmorphism and abnormal fifth digits

Related symptoms:

  • Global developmental delay
  • Hearing impairment
  • Hypertelorism
  • Strabismus
  • Abnormal facial shape


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about CHAR SYNDROME

Low match COG7-CDG


COG7-CDG is a congenital disorder of glycosylation characterised by dysmorphism, skeletal dysplasia, hypotonia, hepatosplenomegaly, jaundice, cardiac insufficiency, recurrent infections and epilepsy. To date, it has been described in two infants, both of whom died within the first three months of life. The syndrome is caused by a mutation in the gene encoding COG-7 (chromosome 16), a subunit of the oligomeric Golgi complex.

COG7-CDG Is also known as carbohydrate deficient glycoprotein syndrome type iie|congenital disorder of glycosylation type 2e|cdg iie|cdg syndrome type iie|cdg2e|congenital disorder of glycosylation type iie|cdg-iie|cdgiie

Related symptoms:

  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Microcephaly
  • Growth delay


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about COG7-CDG

Top 5 symptoms//phenotypes associated to Congestive heart failure and Gynecomastia

Symptoms // Phenotype % cases
Hirsutism Uncommon - Between 30% and 50% cases
Global developmental delay Uncommon - Between 30% and 50% cases
Fatigue Uncommon - Between 30% and 50% cases
Osteoporosis Uncommon - Between 30% and 50% cases
Hypogonadism Uncommon - Between 30% and 50% cases
Mendelian

Accelerate your rare disease diagnosis with us

Learn more

Other less frequent symptoms

Patients with Congestive heart failure and Gynecomastia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Growth hormone excess Nevus Thick vermilion border Blindness Vomiting Weight loss Infertility Prolactin excess Acne Growth delay Ovarian cyst Seizures Depressed nasal bridge Hearing impairment Neoplasm Pituitary adenoma Increased circulating cortisol level Precocious puberty Cafe-au-lait spot Hypertension Goiter Hepatomegaly

Rare Symptoms - Less than 30% cases


Thickened skin Abdominal distention Thyroid follicular hyperplasia Abnormality of the liver Abnormal facial shape Proteinuria Hypothyroidism Nephrocalcinosis Decreased liver function Cardiac myxoma Neoplasm of the skin Elevated alkaline phosphatase Elevated hepatic transaminase Hyperostosis Multinodular goiter Profuse pigmented skin lesions Testicular neoplasm Intellectual disability Freckling Tall stature Neoplasm of the breast Increased body weight Ovarian neoplasm Hypermelanotic macule Neurofibromas Subcutaneous nodule Pituitary prolactin cell adenoma Polycystic ovaries Thyroid carcinoma Sleep disturbance Schwannoma Red hair Multiple lentigines Precocious puberty in females Hepatosplenomegaly Broad nasal tip Protruding ear Respiratory failure High forehead Short neck Kyphoscoliosis Deeply set eye Abnormality of the pinna Respiratory insufficiency Abnormal heart morphology Short philtrum Broad forehead Feeding difficulties Strabismus Failure to thrive Cholelithiasis Clinodactyly of the 5th finger Abnormality of cardiovascular system morphology Short stature Motor delay Scoliosis Polydactyly Hypertelorism Micrognathia Low-set ears Patent ductus arteriosus Clinodactyly Kyphosis Wide nasal bridge Downslanted palpebral fissures Abnormality of the skeletal system Ventricular septal defect Behavioral abnormality Anteverted nares Peripheral neuropathy Jaundice Progressive visual loss Osteopenia Vertigo Pericardial effusion Retinopathy Impotence Hyperhidrosis Hypogonadotrophic hypogonadism Pallor Pain Cardiomyopathy Abnormality of the pituitary gland Female hypogonadism Alopecia Delayed puberty Palpitations Splenomegaly Ptosis Hyperthyroidism Papule Diabetes mellitus Cholestasis Stroke Menstrual irregularities Hyperpigmentation of the skin Male hypogonadism Myalgia Cirrhosis Dyspnea Ascites Hepatic steatosis Fever Respiratory distress Abnormal renal physiology Abnormal renal morphology Arteriosclerosis Esophageal varix Elevated C-reactive protein level Decreased HDL cholesterol concentration Urinary retention Tubulointerstitial fibrosis Restrictive cardiomyopathy Endocardial fibroelastosis High-frequency hearing impairment Testicular atrophy Retinal pigment epithelial atrophy Abnormal left ventricle morphology Disinhibition Confusion Achromatopsia Poor fine motor coordination Abnormal spermatogenesis Urethral obstruction Squared iliac bones Renovascular hypertension Albuminuria Abnormal muscle tone Impaired temperature sensation Urethral stricture Abnormal chorioretinal morphology Epigastric pain Abnormality of dental color Lumbar scoliosis Abnormality of the urethra Chronic infection Decreased glomerular filtration rate Pyelonephritis Abnormality of the optic disc First degree atrioventricular block Melena Hematemesis Frontal balding Increased total bilirubin Vertical nystagmus Bull's eye maculopathy Abnormality of female external genitalia Hepatic encephalopathy Urethral stenosis Chronic fatigue Acute pancreatitis Chills Chronic obstructive pulmonary disease Attenuation of retinal blood vessels Myocardial fibrosis Obsessive-compulsive behavior Chorioretinal atrophy Abnormal retinal morphology Truncal obesity Urinary urgency Hydroureter Pulmonary fibrosis Emphysema Polyuria Glucose intolerance Diabetes insipidus Hyperglycemia Impaired vibratory sensation Constriction of peripheral visual field Aplasia/Hypoplasia of the cerebellum Chronic otitis media Short finger Nephritis Polydipsia Portal hypertension Lipodystrophy Hyperinsulinemia Abnormality of the hand Cone/cone-rod dystrophy Tachypnea Hypercholesterolemia Pancreatitis Hyperlipidemia Atherosclerosis Acanthosis nigricans Macular degeneration Polyphagia Agenesis of permanent teeth Oligospermia Poor coordination Myocarditis Tubular atrophy Recurrent bronchitis Acute hepatic failure Elevated serum creatinine Right ventricular hypertrophy Hepatic necrosis Tubulointerstitial nephritis Pendular nystagmus Gingivitis Ketoacidosis Broad foot Posterior subcapsular cataract Oligomenorrhea Hyperventilation Progressive sensorineural hearing impairment Pericarditis Glomerulopathy Glycosuria Bronchitis Hyperuricemia Increased number of teeth Subcapsular cataract Thoracic scoliosis Alopecia of scalp Autoimmune thrombocytopenia Severe sensorineural hearing impairment Hypoventilation Insulin-resistant diabetes mellitus Retinal atrophy Peripheral visual field loss Hypoplastic male external genitalia Receptive language delay Chronic hepatic failure Toe syndactyly Prominent occiput Supernumerary nipple Hand polydactyly Coarse hair Bicuspid aortic valve Finger clinodactyly Depressed nasal ridge Coarctation of aorta Premature birth Hypodontia Highly arched eyebrow Everted lower lip vermilion Thick eyebrow Craniosynostosis Persistence of primary teeth Syndactyly Malar flattening Long philtrum Short nose Intellectual disability, mild Myopia Intra-oral hyperpigmentation Abnormality of circulating adrenocorticotropin level Sertoli cell neoplasm Pigmentation of the sclera Abnormal pigmentation of the oral mucosa Peripheral Schwannoma Blue nevus Short middle phalanx of the 5th finger Triangular mouth Pigmented micronodular adrenocortical disease Hypertrophic cardiomyopathy Abnormal glycosylation Areflexia of lower limbs Premature skin wrinkling Distal arthrogryposis Inverted nipples Protruding tongue Abnormality of immune system physiology Adducted thumb Dehydration Delayed myelination Polyneuropathy Flat face Arthrogryposis multiplex congenita Areflexia Mesoaxial hand polydactyly Thrombocytopenia Recurrent infections Cerebral atrophy Diarrhea Anemia Muscular hypotonia Microcephaly Generalized hypotonia Distal/middle symphalangism of 5th finger Mesoaxial foot polydactyly Symphalangism of the 5th finger Muscular ventricular septal defect Parasomnia No permanent dentition Hepatocellular adenoma Histiocytoma Facial hirsutism Unilateral breast hypoplasia Recurrent fractures Talipes Macrocephaly Abnormality of the femoral head Vitreous haze Localized hirsutism Abnormality of renal calyx morphology Abnormality of prothrombin EEG with occipital slowing Abnormal retinal artery morphology Widely-spaced incisors Recurrent cystitis Glue ear Dilatation of the bladder Hemiplegia/hemiparesis Thickened ears Granular macular appearance Absence seizures Hyperostosis frontalis interna Chronic active hepatitis Abnormal adipose tissue morphology Nonproductive cough Exudative retinopathy Increased circulating androgen level High-frequency sensorineural hearing impairment Childhood-onset truncal obesity Multifocal atrial tachycardia ST segment depression Reduced bone mineral density Hamartoma Bronchogenic cyst Adrenocortical carcinoma Uterine neoplasm Hypertension associated with pheochromocytoma Nodular goiter Vestibular Schwannoma Fibroadenoma of the breast Increased urinary cortisol level Adrenal pheochromocytoma Pituitary growth hormone cell adenoma Abnormal prolactin level Recurrent paroxysmal headache Osteochondroma Pancreatic adenocarcinoma Thyroid adenoma Enlarged polycystic ovaries Arteriovenous malformation Hypoplasia of the musculature Stomach cancer Parathyroid adenoma Neoplasm of the endocrine system Neoplasm of the pancreas Colon cancer Sudden cardiac death Neoplasm of the thyroid gland Upper limb asymmetry Lymphangioma Excessive wrinkled skin Visceral angiomatosis Venous insufficiency Lower limb asymmetry Accelerated skeletal maturation Recurrent otitis media Generalized hirsutism Hemianopia Hernia Cranial nerve paralysis Intellectual disability, severe Ventricular arrhythmia Talipes equinovarus Easy fatigability Hypokalemia Brachydactyly Increased circulating gonadotropin level High palate Flexion contracture Adrenocorticotropic hormone deficiency Supraventricular arrhythmia Diplopia Abnormality of the menstrual cycle Oculomotor nerve palsy Secondary growth hormone deficiency Monostotic fibrous dysplasia Large cafe-au-lait macules with irregular margins Decreased fertility in females Polyostotic fibrous dysplasia Thyroid nodule Axillary freckling Myelofibrosis Decreased female libido Hamartomatous polyposis Pseudohypoparathyroidism Pectus excavatum Inguinal hernia Craniofacial hyperostosis Corneal opacity Bowing of the long bones Interphalangeal joint contracture of finger Mitral valve prolapse Hip dysplasia Dental malocclusion Full cheeks Delayed eruption of teeth Single transverse palmar crease Tremor Short palm Thin vermilion border Smooth philtrum Genu valgum Headache Prominent forehead Camptodactyly of finger Wide mouth Joint stiffness Camptodactyly Nausea and vomiting Umbilical hernia Coarse facial features Skeletal dysplasia Hypotension Mandibular prognathia Proptosis Glaucoma Brachycephaly Sudden loss of visual acuity Intestinal polyposis Short phalanx of finger Muscle weakness Fourth cranial nerve palsy Uterine leiomyoma Follicular thyroid carcinoma Follicular hyperplasia Internal ophthalmoplegia Abnormal visual field test Fibroma Abnormality of hair density Heteronymous hemianopia Thyroid crisis Paraganglioma Pheochromocytoma Generalized hypopigmentation Cranial nerve VI palsy Macroorchidism Blue irides Bipolar affective disorder Striae distensae Macule Proximal muscle weakness Heart murmur Sarcoma Ischemic stroke Hemangioma Carcinoma Abnormality of the eye Abnormality of the skin Enlarged pituitary gland Myxoid subcutaneous tumors Pituitary hypothyroidism Hypercalciuria Osteosarcoma Syringomyelia Osteomalacia Hyperparathyroidism Abnormality of the thyroid gland Pathologic fracture Hypophosphatemia Adrenal insufficiency Decreased circulating ACTH level Increased thyroid-stimulating hormone level Rickets Hypercalcemia Central adrenal insufficiency Adrenocorticotropin deficient adrenal insufficiency Cutaneous myxoma Aspiration Decreased fertility in males Nephrolithiasis Primary amenorrhea Amenorrhea Bitemporal hemianopia Facial asymmetry Synophrys Autoimmunity Erectile abnormalities Hyperactivity Periodic hypokalemic paresis Euthyroid hyperthyroxinemia Abnormality of the hypothalamus-pituitary axis Gingival overgrowth Horizontal nystagmus Hypotrichosis Retinal dystrophy Hepatic failure Tachycardia Nausea Stage 5 chronic kidney disease Lymphadenopathy Retinal degeneration Dry skin Carious teeth Pulmonic stenosis Ophthalmoplegia Hypermetropia Generalized tonic-clonic seizures Arthralgia Dilated cardiomyopathy Cough Nyctalopia Scarring Sparse hair Autistic behavior Respiratory tract infection Postnatal growth retardation Irritability Abnormality of the kidney Conductive hearing impairment Photophobia Pes planus Nephropathy Asthma Autism Pulmonary arterial hypertension Recurrent pneumonia Hypergonadotropic hypogonadism Short toe Sinusitis Hepatic fibrosis Insulin resistance Abnormality of retinal pigmentation Anorexia Chronic diarrhea Left ventricular hypertrophy Recurrent urinary tract infections Involuntary movements Hypertriglyceridemia Epidermal acanthosis Vesicoureteral reflux Type II diabetes mellitus Cardiomegaly Optic disc pallor Hepatitis Pigmentary retinopathy Cyanosis Specific learning disability Decreased testicular size Otitis media Growth hormone deficiency Gastrointestinal hemorrhage Round face Urinary incontinence Gastroesophageal reflux Hyperkeratosis Wide anterior fontanel Premature loss of teeth Broad clavicles Multiple skeletal anomalies Hyperplasia of the maxilla Broad alveolar ridges Thoracolumbar kyphosis Vacuolated lymphocytes Anterior segment developmental abnormality Buphthalmos Concave nasal ridge Beaking of vertebral bodies Abnormally large globe Genu recurvatum Double outlet right ventricle Megalocornea Serpentine fibula Aseptic necrosis Congenital glaucoma Delayed cranial suture closure Flared metaphysis Metatarsus adductus Tricuspid regurgitation Flat occiput Chondrocalcinosis Short long bone Abnormality of the metacarpal bones Osteolysis Short chin Wormian bones Prominent coccyx Cortical irregularity Limitation of joint mobility Dystonia Abdominal pain Myoclonus Rod-cone dystrophy Recurrent respiratory infections Pneumonia Constipation Hyporeflexia Visual loss Encephalopathy Depressivity Obesity Dilatation Renal insufficiency Joint dislocation Anterior concavity of thoracic vertebrae Abnormality of the dentition Arthropathy Optic atrophy Visual impairment Delayed speech and language development Hepatocellular carcinoma Cognitive impairment Cataract Sensorineural hearing impairment Exocrine pancreatic insufficiency Increased serum ferritin Nystagmus Ataxia Mild proteinuria



If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like Frontal bossing and Abnormality of the dentition, related diseases and genetic alterations Ventricular septal defect and Anal atresia, related diseases and genetic alterations

Need help with a diagnosis?

Learn more about how to achieve it with Mendelian


Learn more