Cardiomyopathy, and Migraine

Diseases related with Cardiomyopathy and Migraine

In the following list you will find some of the most common rare diseases related to Cardiomyopathy and Migraine that can help you solving undiagnosed cases.


Top matches:

Medium match SENSORY ATAXIC NEUROPATHY-DYSARTHRIA-OPHTHALMOPARESIS SYNDROME


Sensory ataxic neuropathy-dysarthria-ophthalmoparesis syndrome is characterised by adult-onset severe sensory ataxic neuropathy, dysarthria and chronic progressive external ophthalmoplegia.

SENSORY ATAXIC NEUROPATHY-DYSARTHRIA-OPHTHALMOPARESIS SYNDROME Is also known as sando

Related symptoms:


SOURCES: ORPHANET MENDELIAN

More info about SENSORY ATAXIC NEUROPATHY-DYSARTHRIA-OPHTHALMOPARESIS SYNDROME

Medium match CYCLIC VOMITING SYNDROME; CVS


Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Hearing impairment


SOURCES: OMIM MENDELIAN

More info about CYCLIC VOMITING SYNDROME; CVS

Medium match ADULT-ONSET CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL MYOPATHY


Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy is a rare mitochondrial disease characterized by adult onset of progressive external ophthalmoplegia, exercise intolerance, muscle weakness, manifestations of spinocerebellar ataxia (e.g. impaired gait, dysarthria) and mild motor peripheral neuropathy. Respiratory insufficiency has been reported in some cases.

ADULT-ONSET CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL MYOPATHY Is also known as adult-onset cpeo with mitochondrial myopathy

Related symptoms:


SOURCES: ORPHANET MENDELIAN

More info about ADULT-ONSET CHRONIC PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL MYOPATHY

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Other less relevant matches:

Medium match TAKAYASU ARTERITIS


Takayasu arteritis (TAK) is a rare inflammatory large-vessel vasculitis primarily affecting the aorta and its major branches, but also other large vessels, causing stenosis, occlusion, or aneurysm.

TAKAYASU ARTERITIS Is also known as young female arteritis|aortic arch syndrome|pulseless disease

Related symptoms:

  • Seizures
  • Muscle weakness
  • Anemia
  • Hypertension
  • Fever


SOURCES: ORPHANET OMIM MENDELIAN

More info about TAKAYASU ARTERITIS

Medium match SPINOCEREBELLAR ATAXIA WITH EPILEPSY


Spinocerebellar ataxia with epilepsy is a rare, mitochondrial DNA maintenance syndrome characterized by cerebellar ataxia, sensory peripheral neuropathy, myoclonus, epilepsy, progressive cognitive impairment, late-onset ptosis and external ophthalmoplegia. Liver failure may also occur, most often in association with the use of antiepileptic drug sodium valproate.

SPINOCEREBELLAR ATAXIA WITH EPILEPSY Is also known as mitochondrial spinocerebellar ataxia with epilepsy|mscae|sensory ataxic neuropathy with mitochondrial dna deletions, autosomal recessive|scae

Related symptoms:

  • Seizures
  • Hearing impairment
  • Ataxia
  • Nystagmus
  • Sensorineural hearing impairment


SOURCES: OMIM ORPHANET MENDELIAN

More info about SPINOCEREBELLAR ATAXIA WITH EPILEPSY

Medium match COL4A1-RELATED FAMILIAL VASCULAR LEUKOENCEPHALOPATHY


COL4A1-related familial vascular leukoencephalopathy is a rare, genetic, neurological disease characterized by the presence of fragile small-vessel intracerebral vasculature in various members of a single family, manifesting, clinically, with single or recurrent hemorrhagic and/or ischemic stroke and, frequently, ocular and renal involvement. Neuroimaging reveals diffuse, periventricular leukoencephalopathy associated with dilated perivascular spaces, lacunar infarction and microhemorrhages.

COL4A1-RELATED FAMILIAL VASCULAR LEUKOENCEPHALOPATHY Is also known as col4a1-related brain small vessel disease with hemorrhage|leukoencephalopathy with axenfeld-rieger anomaly|brain small vessel disease with axenfeld-rieger anomaly|brain small vessel disease with hemorrhage|infantile hemiparesis|retinal arteriolar tortuosi

Related symptoms:

  • Seizures
  • Global developmental delay
  • Hearing impairment
  • Microcephaly
  • Nystagmus


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about COL4A1-RELATED FAMILIAL VASCULAR LEUKOENCEPHALOPATHY

Medium match ATTRV30M AMYLOIDOSIS


Familial amyloid polyneuropathy (FAP) or transthyretin (TTR) amyloid polyneuropathy is a progressive sensorimotor and autonomic neuropathy of adulthood onset. Weight loss and cardiac involvement are frequent; ocular or renal complications may also occur.

ATTRV30M AMYLOIDOSIS Is also known as familial amyloid polyneuropathy type i|ttr amyloid neuropathy|attrv30m-related amyloidosis|hereditary amyloidosis, transthyretin-related|transthyretin amyloid polyneuropathy|familial amyloid polyneuropathy, portuguese-swedish-japanese type|fap|amyloid pol

Related symptoms:

  • Seizures
  • Hearing impairment
  • Ataxia
  • Nystagmus
  • Sensorineural hearing impairment


SOURCES: OMIM ORPHANET MENDELIAN

More info about ATTRV30M AMYLOIDOSIS

Medium match PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS, AUTOSOMAL DOMINANT 3; PEOA3


Progressive external ophthalmoplegia is characterized by multiple mitochondrial DNA deletions in skeletal muscle. The most common clinical features include adult onset of weakness of the external eye muscles and exercise intolerance. Patients with C10ORF2-linked adPEO may have other clinical features including proximal muscle weakness, ataxia, peripheral neuropathy, cardiomyopathy, cataracts, depression, and endocrine abnormalities (summary by Fratter et al., 2010).For a general phenotypic description and a discussion of genetic heterogeneity of autosomal dominant progressive external ophthalmoplegia, see PEOA1 (OMIM ).PEO caused by mutations in the POLG gene (OMIM ) are associated with more complicated phenotypes than those forms caused by mutations in the SLC25A4 (OMIM ) or C10ORF2 genes (Lamantea et al., 2002).

PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS, AUTOSOMAL DOMINANT 3; PEOA3 Is also known as progressive external ophthalmoplegia, autosomal dominant 3

Related symptoms:

  • Seizures
  • Global developmental delay
  • Short stature
  • Hearing impairment
  • Ataxia


SOURCES: MESH OMIM MENDELIAN

More info about PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS, AUTOSOMAL DOMINANT 3; PEOA3

Medium match ACROMEGALY


Acromegaly is an acquired disorder related to excessive production of growth hormone (GH) and characterized by progressive somatic disfigurement (mainly involving the face and extremities) and systemic manifestations.

Related symptoms:

  • Neoplasm
  • Hypertension
  • Fatigue
  • Frontal bossing
  • Abnormality of the dentition


SOURCES: ORPHANET MENDELIAN

More info about ACROMEGALY

Medium match GLUTARYL-COA DEHYDROGENASE DEFICIENCY


Glutaryl-CoA dehydrogenase (GCDH) deficiency (GDD) is an autosomal recessive neurometabolic disorder clinically characterized by encephalopathic crises resulting in striatal injury and a severe dystonic dyskinetic movement disorder.

GLUTARYL-COA DEHYDROGENASE DEFICIENCY Is also known as ga i|glutaric aciduria i|gcdhd|ga1|glutaryl-coenzyme a dehydrogenase deficiency|glutaric aciduria type 1|glutaric acidemia type 1|glutaryl-coa dehydrogenase deficiency

Related symptoms:

  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Ataxia
  • Failure to thrive


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about GLUTARYL-COA DEHYDROGENASE DEFICIENCY

Top 5 symptoms//phenotypes associated to Cardiomyopathy and Migraine

Symptoms // Phenotype % cases
Seizures Common - Between 50% and 80% cases
Muscle weakness Uncommon - Between 30% and 50% cases
Ataxia Uncommon - Between 30% and 50% cases
Headache Uncommon - Between 30% and 50% cases
Hearing impairment Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Cardiomyopathy and Migraine. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Tremor Fatigue Gliosis Global developmental delay Paresthesia Hyperhidrosis Myopathy Depressivity Fever Dysarthria Visual impairment Dementia Cognitive impairment Areflexia Hyporeflexia Gait disturbance Elevated serum creatine phosphokinase Exercise intolerance Peripheral neuropathy Dysphagia Neuronal loss in central nervous system Weight loss Dilatation Impotence Cataract Nystagmus Sensorineural hearing impairment Vomiting Sensory ataxia Pain

Rare Symptoms - Less than 30% cases


Subsarcolemmal accumulations of abnormally shaped mitochondria Ophthalmoplegia Retinal hemorrhage Proximal muscle weakness Acidosis Cytochrome C oxidase-negative muscle fibers Multiple mitochondrial DNA deletions Hemiplegia Encephalopathy Hemiparesis Muscle cramps Nephropathy Cerebral palsy Facial palsy Ptosis Stroke Abnormality of eye movement Peripheral axonal neuropathy Intracranial hemorrhage Bilateral ptosis Decreased number of peripheral myelinated nerve fibers Dysphonia Axonal degeneration Progressive external ophthalmoplegia Leukoencephalopathy Sensory axonal neuropathy Ophthalmoparesis Progressive hearing impairment Polyneuropathy External ophthalmoplegia Status epilepticus Spastic paraparesis Increased serum lactate Brain atrophy Paraparesis Acute encephalopathy Cerebral hemorrhage Ragged-red muscle fibers Abnormality of the cerebral white matter Abnormality of mitochondrial metabolism Rigidity Neurological speech impairment Hypertrophic cardiomyopathy Arthritis Myalgia Arthralgia Hypertension Diabetes mellitus Abnormal autonomic nervous system physiology Coma Anorexia Vertigo Malnutrition Diarrhea Motor delay Muscular hypotonia Strabismus Microcephaly Generalized hypotonia Vasculitis Retinopathy Cerebral ischemia Spasticity Arrhythmia Vitreous floaters Hypogonadism Left ventricular hypertrophy Cerebral atrophy Respiratory insufficiency Skeletal muscle atrophy Short stature Wide nose Amyloid deposition in the vitreous humor Cardiac amyloidosis Tapered finger Macroglossia Parkinsonism Bradykinesia Apathy Progressive muscle weakness Full cheeks Thick lower lip vermilion Osteoarthritis Mitral regurgitation Diplopia Hoarse voice Orthostatic hypotension due to autonomic dysfunction Tall stature Bradycardia EMG: myopathic abnormalities Thickened skin Ventricular hypertrophy Ventricular fibrillation Amenorrhea Hypothyroidism Mitochondrial myopathy Sensory neuropathy Limb-girdle muscle weakness Neoplasm Frontal bossing Bipolar affective disorder Lower limb muscle weakness Abnormality of the dentition Limb muscle weakness Severe global developmental delay Memory impairment Kyphosis Mandibular prognathia Generalized muscle weakness Macrotia Coarse facial features Mutism Insomnia Anxiety Resting tremor Broad forehead Abnormality of the thyroid gland Coronary artery atherosclerosis Synophrys Long face Cerebral cortical atrophy Premature ovarian insufficiency Intellectual disability Generalized hirsutism Metabolic acidosis Choreoathetosis Abnormality of extrapyramidal motor function Dehydration Aciduria Delayed myelination Abnormal cerebellum morphology Dyskinesia Joint dislocation Inability to walk Abnormality of movement Paralysis Respiratory tract infection Irritability Developmental regression Feeding difficulties in infancy Large fontanelles Hyperkinesis Prominent forehead Decreased plasma carnitine Ketonemia Symmetrical progressive peripheral demyelination Macrocephaly at birth Glutaric acidemia Glutaric aciduria Infantile encephalopathy Fasting hypoglycemia Dilation of lateral ventricles Encephalitis Abnormality of the retinal vasculature Ketonuria Generalized dystonia Malignant hyperthermia Bulbar palsy Opisthotonus Spastic diplegia Hypoglycemia Dystonia Abnormality of the fingernails Palpebral edema Neoplasm of the endocrine system Dysuria Abnormality of the endocrine system Abnormal toenail morphology Broad foot Growth hormone excess Joint swelling Spinal canal stenosis Anterior hypopituitarism Generalized hyperpigmentation Large hands Acne Growth abnormality Sleep apnea Widely spaced teeth Acanthosis nigricans Deep palmar crease Pheochromocytoma Edema Broad jaw Macrocephaly Hepatomegaly Feeding difficulties Abnormal facial shape Failure to thrive Cortical diaphyseal thickening of the upper limbs Abnormality of reproductive system physiology Macrodactyly Long penis Dysmenorrhea Pituitary prolactin cell adenoma Deep plantar creases Galactorrhea Urinary retention Hypersomnia Paraganglioma Psychomotor deterioration Corneal neovascularization Abnormal renal physiology Limb ataxia Pes cavus Myoclonus Gait ataxia EEG abnormality Mental deterioration Distal muscle weakness Dilated cardiomyopathy Lactic acidosis Falls Distal sensory impairment Progressive cerebellar ataxia Generalized myoclonic seizures Focal-onset seizure Frequent falls Cerebral visual impairment Blindness Intestinal pseudo-obstruction Sensory ataxic neuropathy Impaired distal proprioception Impaired distal vibration sensation Muscle fiber necrosis Gastroparesis Positive Romberg sign Progressive gait ataxia Increased variability in muscle fiber diameter Hyperventilation Axonal loss Centrally nucleated skeletal muscle fibers Gaze-evoked nystagmus Vestibular dysfunction Mildly elevated creatine phosphokinase Pneumonia Increased inflammatory response Myopia Lethargy Pulmonary arterial hypertension Chest pain Anemia Gastrointestinal dysmotility Nausea Nausea and vomiting Attention deficit hyperactivity disorder Subcutaneous nodule Pallor Photophobia Autism Abdominal pain Behavioral abnormality Growth delay Myocardial infarction Skin ulcer Hypertensive crisis Abnormal pattern of respiration Arteritis Gastrointestinal infarctions Amaurosis fugax Abnormal endocardium morphology Ascending tubular aorta aneurysm Arterial stenosis Inflammatory abnormality of the eye Aortic regurgitation Abnormal aortic valve morphology Reduced consciousness/confusion Gangrene Hemoptysis Abnormal heart valve morphology Psoriasiform dermatitis Atrophy/Degeneration involving the spinal cord Cerebellar atrophy Myelopathy Hypotension Optic neuritis Retinal arteriolar tortuosity Peripapillary atrophy Right hemiplegia Retinal arterial tortuosity Posterior leukoencephalopathy Thalamic hemorrhage Hydrocephalus Congestive heart failure Renal insufficiency Constipation Malabsorption Paraplegia Urinary incontinence Peripheral demyelination Perivascular spaces Amyloidosis Constrictive median neuropathy Stroke-like episode Multiple myeloma Restrictive cardiomyopathy Increased CSF protein Syringomyelia Orthostatic hypotension Bilateral sensorineural hearing impairment Aphasia Rheumatoid arthritis Cachexia Atrioventricular block Hallucinations Cardiomegaly Diffuse leukoencephalopathy Polycoria Intellectual disability, mild Tachycardia Tetraplegia Renal cyst Microcornea Hypopigmentation of the skin Retinal detachment Hematuria Astigmatism Amblyopia Congenital cataract Hypermetropia Corneal opacity Abnormality of the nervous system Glaucoma Microphthalmia Spastic tetraplegia Blurred vision Rieger anomaly Anterior segment developmental abnormality Arterial tortuosity Neuritis Migraine with aura Porencephalic cyst Hypopigmentation of the fundus Anterior synechiae of the anterior chamber Supraventricular tachycardia Congenital glaucoma Ectopia pupillae Increased intraocular pressure Hypoplasia of the iris Posterior embryotoxon Infantile spasms Scotoma Subdural hemorrhage



If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like Frontal bossing and Hyperhidrosis, related diseases and genetic alterations Melanoma and Everted lower lip vermilion, related diseases and genetic alterations Congestive heart failure and Pallor, related diseases and genetic alterations Tremor and Congenital diaphragmatic hernia, related diseases and genetic alterations

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