Cardiomyopathy, and Hypotension

Diseases related with Cardiomyopathy and Hypotension

In the following list you will find some of the most common rare diseases related to Cardiomyopathy and Hypotension that can help you solving undiagnosed cases.

Top matches:

Related symptoms:

  • Muscle weakness
  • Fatigue
  • Cardiomyopathy
  • Myopathy
  • Congestive heart failure


SOURCES: OMIM MESH MENDELIAN

More info about CARDIOMYOPATHY, DILATED, 1I; CMD1I

Related symptoms:

  • Cardiomyopathy
  • Hypertrophic cardiomyopathy
  • Tachycardia
  • Hypotension
  • Atrial fibrillation


SOURCES: OMIM MESH MENDELIAN

More info about CARDIOMYOPATHY, FAMILIAL RESTRICTIVE, 3; RCM3

A group of conditions in which HEART VENTRICLE activation by the atrial impulse is faster than the normal impulse conduction from the SINOATRIAL NODE. In these pre-excitation syndromes, atrial impulses often bypass the ATRIOVENTRICULAR NODE delay and travel via ACCESSORY CONDUCTING PATHWAYS connecting the atrium directly to the BUNDLE OF HIS.

WOLFF-PARKINSON-WHITE SYNDROME Is also known as wpw syndrome

Related symptoms:

  • Pain
  • Respiratory distress
  • Cardiomyopathy
  • Congestive heart failure
  • Arrhythmia


SOURCES: OMIM ORPHANET MENDELIAN

More info about WOLFF-PARKINSON-WHITE SYNDROME

Other less relevant matches:

Transthyretin (TTR)-related familial amyloidotic cardiomyopathy is a hereditary TTR-related systemic amyloidosis (ATTR) with predominant cardiac involvement resulting from myocardial infiltration of abnormal amyloid protein.

ATTRV122I AMYLOIDOSIS Is also known as attr cardiomyopathy|attrv122i-related amyloidosis|transthyretin-related familial amyloid cardiomyopathy|transthyretin amyloid cardiopathy|ttr-related amyloid cardiomyopathy|ttr-related cardiac amyloidosis

Related symptoms:

  • Muscle weakness
  • Cardiomyopathy
  • Diarrhea
  • Congestive heart failure
  • Arrhythmia


SOURCES: ORPHANET MENDELIAN

More info about ATTRV122I AMYLOIDOSIS

AGel amyloidosis is a rare, systemic amyloidosis characterized by a triad of ophthalmologic, neurologic and dermatologic findings due to the deposition of gelsolin amyloid fibrils in these tissues. Clinical manifestations include corneal lattice dystrophy, cranial neuropathy, especially affecting the facial nerve, bulbar signs, cutis laxa, increased skin fragility, and less commonly peripheral neuropathy and renal failure.

AGEL AMYLOIDOSIS Is also known as amyloid cranial neuropathy with lattice corneal dystrophy|amyloidosis, meretoja type|amyloidosis due to mutant gelsolin|amyloidosis v|familial amyloidosis, finnish type|gelsolin amyloidosis|familial amyloid polyneuropathy type iv|hereditary amyloidosis, f

Related symptoms:

  • Cataract
  • Ptosis
  • Peripheral neuropathy
  • Cardiomyopathy
  • Renal insufficiency


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about AGEL AMYLOIDOSIS

Familial glucocorticoid deficiency is a rare autosomal recessive disorder characterized by an inability of the adrenal cortex to produce cortisol in response to stimulation by adrenocorticotropic hormone (ACTH). Affected individuals typically present within the first few months of life with symptoms related to cortisol deficiency, including failure to thrive, recurrent illnesses or infections, hypoglycemia, convulsions, and shock. The disease is life-threatening if untreated (summary by Meimaridou et al., 2012).For a discussion of genetic heterogeneity of familial glucocorticoid deficiency, see GCCD1 (OMIM ).

Related symptoms:

  • Seizures
  • Neoplasm
  • Failure to thrive
  • Cryptorchidism
  • Cardiomyopathy


SOURCES: OMIM MENDELIAN

More info about GLUCOCORTICOID DEFICIENCY 4 WITH OR WITHOUT MINERALOCORTICOID DEFICIENCY; GCCD4

FATAL CONGENITAL HYPERTROPHIC CARDIOMYOPATHY DUE TO GLYCOGEN STORAGE DISEASE Is also known as fatal congenital hypertrophic cardiomyopathy due to glycogenosis|fatal congenital hypertrophic cardiomyopathy due to gsd|phosphorylase kinase deficiency of heart|glycogen storage disease of heart

Related symptoms:

  • Seizures
  • Generalized hypotonia
  • Failure to thrive
  • Micrognathia
  • Abnormal facial shape


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about FATAL CONGENITAL HYPERTROPHIC CARDIOMYOPATHY DUE TO GLYCOGEN STORAGE DISEASE

Adult polyglucosan body disease (APBD) is a glycogen storage disease of adults characterized by progressive upper and lower motor neuron dysfunction, progressive neurogenic bladder and cognitive difficulties that can lead to dementia.

ADULT POLYGLUCOSAN BODY DISEASE Is also known as apbd|polyglucosan body disease, adult form

Related symptoms:

  • Intellectual disability
  • Ataxia
  • Muscle weakness
  • Spasticity
  • Cognitive impairment


SOURCES: OMIM ORPHANET MESH MENDELIAN

More info about ADULT POLYGLUCOSAN BODY DISEASE

The mitochondrial trifunctional protein, composed of 4 alpha and 4 beta subunits, catalyzes 3 steps in mitochondrial beta-oxidation of fatty acids: long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD), long-chain enoyl-CoA hydratase, and long-chain thiolase activities. Trifunctional protein deficiency is characterized by decreased activity of all 3 enzymes. Clinically, classic trifunctional protein deficiency can be classified into 3 main clinical phenotypes: neonatal onset of a severe, lethal condition resulting in sudden unexplained infant death (SIDS ), infantile onset of a hepatic Reye-like syndrome, and late-adolescent onset of primarily a skeletal myopathy (Spiekerkoetter et al., 2003).Some patients with MTP deficiency show a protracted progressive course associated with myopathy, recurrent rhabdomyolysis, and sensorimotor axonal neuropathy. These patients tend to survive into adolescence and adulthood (den Boer et al., 2003).See also isolated LCHAD deficiency (OMIM ), which is caused by mutation in the HADHA gene.

MITOCHONDRIAL TRIFUNCTIONAL PROTEIN DEFICIENCY; MTPD Is also known as trifunctional protein deficiency

Related symptoms:

  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Failure to thrive
  • Muscle weakness


SOURCES: OMIM MENDELIAN

More info about MITOCHONDRIAL TRIFUNCTIONAL PROTEIN DEFICIENCY; MTPD

Carnitine-acylcarnitine translocase (CACT) deficiency is a life-threatening, inherited disorder of fatty acid oxidation which usually presents in the neonatal period with severe hypoketotic hypoglycemia, hyperammonemia, cardiomyopathy and/or arrhythmia, hepatic dysfunction, skeletal muscle weakness, and encephalopathy.

CARNITINE-ACYLCARNITINE TRANSLOCASE DEFICIENCY Is also known as cact deficiency

Related symptoms:

  • Seizures
  • Global developmental delay
  • Generalized hypotonia
  • Microcephaly
  • Nystagmus


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about CARNITINE-ACYLCARNITINE TRANSLOCASE DEFICIENCY

Top 5 symptoms//phenotypes associated to Cardiomyopathy and Hypotension

Symptoms // Phenotype % cases
Muscle weakness Uncommon - Between 30% and 50% cases
Congestive heart failure Uncommon - Between 30% and 50% cases
Hypertrophic cardiomyopathy Uncommon - Between 30% and 50% cases
Hypoglycemia Uncommon - Between 30% and 50% cases
Atrial fibrillation Uncommon - Between 30% and 50% cases

Other less frequent symptoms

Patients with Cardiomyopathy and Hypotension. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases

Cardiomegaly Respiratory distress Seizures Atrioventricular block Failure to thrive Cardiac arrest Vomiting Peripheral neuropathy Coma Generalized hypotonia Arrhythmia Orthostatic hypotension Decreased liver function Exercise intolerance Tachycardia Myopathy Bradycardia Peripheral axonal neuropathy

Rare Symptoms - Less than 30% cases

Decreased urine output Hepatic steatosis Impotence Respiratory insufficiency Reduced ejection fraction Biventricular hypertrophy Cardiac amyloidosis Hypoketotic hypoglycemia Renal insufficiency Rhabdomyolysis Polyneuropathy Hyperammonemia Generalized muscle weakness Hepatic failure Paresthesia Lethargy Muscular hypotonia Acidosis Global developmental delay Hepatomegaly Cyanosis Myoglobinuria Ventriculomegaly Difficulty walking Distal sensory impairment Sensory impairment Elevated hepatic transaminase Myalgia Supraventricular tachycardia Sudden cardiac death Pain Palpitations Dyspnea Sinus bradycardia Atrial flutter Shortened PR interval Left ventricular hypertrophy Dilated cardiomyopathy Ventricular hypertrophy Erectile abnormalities Abnormality of central motor function Decreased/absent ankle reflexes Diarrhea Lafora bodies Cervical spinal cord atrophy Progressive spastic paraparesis Hypokinesia Feeding difficulties Right bundle branch block Edema Dilatation Hyporeflexia Recurrent respiratory infections Abnormal upper motor neuron morphology Motor polyneuropathy Psychomotor deterioration Skin ulcer Urinary incontinence Limitation of joint mobility Left ventricular failure Bradykinesia Abnormality of extrapyramidal motor function Tetraparesis Hemiparesis Lower limb spasticity Progressive muscle weakness Restrictive cardiomyopathy Foot dorsiflexor weakness Mildly reduced ejection fraction EMG abnormality Reduced tendon reflexes Amyotrophic lateral sclerosis Urinary urgency Abnormality of the periventricular white matter Urinary bladder sphincter dysfunction Slow saccadic eye movements Hypomimic face Corpus callosum atrophy Neurogenic bladder CNS demyelination Respiratory failure Retinopathy Ventricular escape rhythm Ventricular extrasystoles Encephalopathy Elevated serum creatine phosphokinase Abnormality of the nervous system Apnea Irritability Aciduria Progressive neurologic deterioration Ventricular tachycardia Cardiorespiratory arrest Microcephaly Hypothermia Preeclampsia Decreased plasma carnitine Fasting hypoglycemia Dicarboxylic aciduria Oliguria Elevated plasma acylcarnitine levels Elevated creatine kinase after exercise Sudden episodic apnea Nystagmus Respiratory failure requiring assisted ventilation Respiratory tract infection Hydrops fetalis Abnormality of the liver Distal muscle weakness Paraplegia Small for gestational age Reduced systolic function Lactic acidosis Metabolic acidosis Muscle cramps Pigmentary retinopathy Tachypnea Acute hepatic steatosis Decreased nerve conduction velocity Tricuspid regurgitation Hypoparathyroidism Skeletal myopathy Progressive peripheral neuropathy Abnormality of the amniotic fluid Recurrent myoglobinuria Prenatal maternal abnormality Exercise-induced rhabdomyolysis Abnormal mitochondrial shape Spastic paraplegia Abnormality of the cerebral white matter Abnormality of abdomen morphology Corneal opacity Poor speech Everted lower lip vermilion Nephrotic syndrome Abnormal autonomic nervous system physiology Cutis laxa Corneal dystrophy Bulbar palsy Amyloidosis Bulbar signs Proteinuria Facial paralysis Mild proteinuria Lattice corneal dystrophy Bilateral facial palsy Generalized amyloid deposition Syncope Neoplasm Chest pain Cryptorchidism Paralysis Glaucoma Hypothyroidism Right ventricular hypertrophy Abnormal cardiac septum morphology Ventricular preexcitation with multiple accessory pathways Paroxysmal supraventricular tachycardia EMG: myopathic abnormalities Ventricular preexcitation Pericardial effusion Exertional dyspnea Heart block Edema of the lower limbs Prolonged QRS complex Ventricular fibrillation Abnormal echocardiogram Atrial arrhythmia Paroxysmal atrial fibrillation Peripheral edema Wolff-Parkinson-White syndrome Abnormal ventricular filling Orthostatic syncope Cataract Ptosis Muscle fibrillation Vertigo Stroke Constipation Cerebellar atrophy Elevated right atrial pressure Pulmonary edema Intellectual disability Ataxia Spasticity Cognitive impairment Gait disturbance Right atrial enlargement Hypoplasia of the corpus callosum Hypertonia Neonatal hypoglycemia Behavioral abnormality Abnormality of metabolism/homeostasis Babinski sign Dementia Cerebral cortical atrophy Gait ataxia Left ventricular systolic dysfunction Mental deterioration Abnormal pyramidal sign Enlarged kidney Heart murmur Anxiety Congenital hypothyroidism Dehydration Hyperpigmentation of the skin Azoospermia Shock Precocious puberty Hyponatremia Apathy Adrenal insufficiency Hyperkalemia Primary adrenal insufficiency Cyanotic episode Renal salt wasting Increased circulating renin level Hypoglycemic coma Hypernatriuria Abnormal heart morphology Micrognathia Abnormal facial shape Fatigue Ascites Macroglossia Abnormality of skeletal muscles


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