Carcinoma, and Dyspnea

Diseases related with Carcinoma and Dyspnea

In the following list you will find some of the most common rare diseases related to Carcinoma and Dyspnea that can help you solving undiagnosed cases.


Top matches:

High match LUNG CANCER


Lung cancer is the leading cause of cancer deaths in the U.S. and worldwide. The 2 major forms of lung cancer are nonsmall cell lung cancer and small cell lung cancer (see {182280}), which account for 85% and 15% of all lung cancers, respectively. Nonsmall cell lung cancer can be divided into 3 major histologic subtypes: squamous cell carcinoma, adenocarcinoma, and large cell lung cancer. Cigarette smoking causes all types of lung cancer, but it is most strongly linked with small cell lung cancer and squamous cell carcinoma. Adenocarcinoma is the most common type in patients who have never smoked. Nonsmall cell lung cancer is often diagnosed at an advanced stage and has a poor prognosis (summary by Herbst et al., 2008).

Related symptoms:

  • Neoplasm
  • Pain
  • Fatigue
  • Respiratory distress
  • Diarrhea


SOURCES: OMIM MENDELIAN

More info about LUNG CANCER

High match OVARIAN CANCER


Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008).

Related symptoms:

  • Neoplasm
  • Pain
  • Fatigue
  • Respiratory distress
  • Vomiting


SOURCES: OMIM ORPHANET MENDELIAN

More info about OVARIAN CANCER

High match THYROID CARCINOMA, FAMILIAL MEDULLARY; MTC


Medullary thyroid carcinoma (MTC) is a malignant tumor of the calcitonin (OMIM )-secreting parafollicular C cells of the thyroid, and occurs sporadically or as a component of the multiple endocrine neoplasia (MEN) type 2 (see {171400})/familial medullary thyroid carcinoma (FMTC) syndromes (summary by Abu-Amero et al., 2006). Thyroid cancer derived from follicular epithelial cells is referred to as nonmedullary thyroid cancer and comprises several subtypes; see {188550}.

THYROID CARCINOMA, FAMILIAL MEDULLARY; MTC Is also known as mtc1|fmtc

Related symptoms:

  • Neoplasm
  • Pain
  • Respiratory distress
  • Hypothyroidism
  • Carcinoma


SOURCES: OMIM MENDELIAN

More info about THYROID CARCINOMA, FAMILIAL MEDULLARY; MTC

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Other less relevant matches:

High match IDIOPATHIC PULMONARY FIBROSIS


Idiopathic pulmonary fibrosis (IPF) is a nonneoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known cause.

IDIOPATHIC PULMONARY FIBROSIS Is also known as cfa|uip|usual interstitial pneumonia|interstitial pneumonitis, usual|idiopathic pulmonary fibrosis, familial|cryptogenic fibrosing alveolitis|fibrosing alveolitis, cryptogenic|fibrocystic pulmonary dysplasia

Related symptoms:

  • Neoplasm
  • Hypertension
  • Fever
  • Respiratory insufficiency
  • Respiratory distress


SOURCES: OMIM ORPHANET MENDELIAN

More info about IDIOPATHIC PULMONARY FIBROSIS

High match ALPHA-1-ANTITRYPSIN DEFICIENCY


Alpha-1-antitrypsin deficiency is a hereditary disease that develops in adulthood and is characterized by chronic liver disorders (cirrhosis), respiratory disorders (emphysema), and rarely panniculitis.

ALPHA-1-ANTITRYPSIN DEFICIENCY Is also known as deficiency in alpa-1-proteinase inhibitor

Related symptoms:

  • Neoplasm
  • Hypertension
  • Hepatomegaly
  • Fatigue
  • Respiratory distress


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about ALPHA-1-ANTITRYPSIN DEFICIENCY

High match LIPOID PROTEINOSIS


Lipoid proteinosis (LP) is a rare genodermatosis characterized clinically by mucocutaneous lesions, hoarseness developing in early childhood and, at times, neurological complications.

LIPOID PROTEINOSIS Is also known as lipoid proteinosis|urbach-wiethe disease|hyalinosis cutis et mucosae

Related symptoms:

  • Intellectual disability
  • Seizures
  • High palate
  • Dysphagia
  • Respiratory distress


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about LIPOID PROTEINOSIS

High match JUVENILE POLYPOSIS SYNDROME; JPS


Juvenile polyposis syndrome is an autosomal dominant condition that predisposes gene carriers to various types of tumors. The diagnosis is based on the occurrence of hamartomatous gastrointestinal polyps that turn into malignant lesions in approximately 20% of cases (Handra-Luca et al., 2005).It had been suggested that juvenile polyposis can be caused by mutations in the PTEN gene (OMIM ), the same gene that is mutant in Cowden syndrome-1 (OMIM ). In a comprehensive review of PTEN, Waite and Eng (2002) concluded that juvenile intestinal polyposis is not a so-called PTEN hamartoma-tumor syndrome (PHTS). They suggested that the discovery of the germline PTEN mutation in an individual considered to have JPS should raise a suspicion that the clinical diagnosis is incorrect and that such an individual should be managed medically in the same manner as all patients with PHTS.

JUVENILE POLYPOSIS SYNDROME; JPS Is also known as polyposis, juvenile intestinal|pji|jip|juvenile intestinal polyposis|polyposis, familial, of entire gastrointestinal tract

Related symptoms:

  • Seizures
  • Neoplasm
  • Failure to thrive
  • Pain
  • Cryptorchidism


SOURCES: OMIM MENDELIAN

More info about JUVENILE POLYPOSIS SYNDROME; JPS

High match CARNEY COMPLEX, TYPE 1; CNC1


Carney complex is an autosomal dominant multiple neoplasia syndrome characterized by cardiac, endocrine, cutaneous, and neural myxomatous tumors, as well as a variety of pigmented lesions of the skin and mucosae. Carney complex may simultaneously involve multiple endocrine glands, similar to classic MEN syndromes (MEN1; {131100} and MEN2; {171400}). Carney complex shows some similarities to McCune-Albright syndrome (MAS ), a sporadic condition that is also characterized by multiple endocrine and nonendocrine tumors, and shares skin abnormalities and some nonendocrine tumors with the lentiginoses and certain of the hamartomatoses, particularly Peutz-Jeghers syndrome (PJS ). Carney complex is often associated with the unusual large-cell calcifying Sertoli cell tumor and psammomatous melanotic schwannomas (Kirschner et al., 2000; Stratakis et al., 2001).

CARNEY COMPLEX, TYPE 1; CNC1 Is also known as lamb syndrome|myxoma, spotty pigmentation, and endocrine overactivity|carney myxoma-endocrine complex|car|carney syndrome|name syndrome

Related symptoms:

  • Neoplasm
  • Muscle weakness
  • Pain
  • Hypertension
  • Fever


SOURCES: OMIM MENDELIAN

More info about CARNEY COMPLEX, TYPE 1; CNC1

High match CYSTIC FIBROSIS


Cystic fibrosis (CF) is a genetic disorder characterized by the production of sweat with a high salt content and mucus secretions with an abnormal viscosity.

CYSTIC FIBROSIS Is also known as mucoviscidosis|cf

Related symptoms:

  • Growth delay
  • Neoplasm
  • Failure to thrive
  • Pain
  • Hypertension


SOURCES: ORPHANET OMIM MENDELIAN

More info about CYSTIC FIBROSIS

High match TUBEROUS SCLEROSIS 1; TSC1


Tuberous sclerosis complex (TSC) is an autosomal dominant multisystem disorder characterized by hamartomas in multiple organ systems, including the brain, skin, heart, kidneys, and lung. Central nervous system manifestations include epilepsy, learning difficulties, behavioral problems, and autism. Renal lesions, usually angiomyolipomas, can cause clinical problems secondary to hemorrhage or by compression and replacement of healthy renal tissue, which can cause renal failure. Patients can also develop renal cysts and renal-cell carcinomas. Pulmonary lymphangioleiomyomatosis can develop in the lungs. Skin lesions include melanotic macules, facial angiofibromas, and patches of connective tissue nevi. There is a wide clinical spectrum, and some patients may have minimal symptoms with no neurologic disability (reviews by Crino et al., 2006 and Curatolo et al., 2008). Genetic Heterogeneity of Tuberous SclerosisSee also tuberous sclerosis-2 (OMIM ), which is caused by mutation in the TSC2 gene (OMIM ) on chromosome 16p13.Approximately 10 to 30% of cases of tuberous sclerosis are due to mutations in the TSC1 gene: the frequency of cases due to mutations in the TSC2 gene is consistently higher. TSC2 mutations are associated with more severe disease (Crino et al., 2006) (see GENOTYPE/PHENOTYPE CORRELATIONS section).

TUBEROUS SCLEROSIS 1; TSC1 Is also known as tuberous sclerosis complex|ts|tuberose sclerosis|tsc

Related symptoms:

  • Intellectual disability
  • Seizures
  • Neoplasm
  • Pain
  • Hypertension


SOURCES: OMIM MENDELIAN

More info about TUBEROUS SCLEROSIS 1; TSC1

Top 5 symptoms//phenotypes associated to Carcinoma and Dyspnea

Symptoms // Phenotype % cases
Respiratory distress Very Common - Between 80% and 100% cases
Neoplasm Very Common - Between 80% and 100% cases
Pain Common - Between 50% and 80% cases
Hypertension Common - Between 50% and 80% cases
Fatigue Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Carcinoma and Dyspnea. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Cough Hemoptysis Weight loss Congestive heart failure Respiratory failure Scarring Bronchiectasis Cirrhosis Abnormal lung morphology Gastroesophageal reflux Clubbing Stroke Portal hypertension Seizures Nausea Respiratory tract infection Abdominal pain Wheezing Vomiting Diarrhea Chest pain

Rare Symptoms - Less than 30% cases


Elevated hepatic transaminase Fibroma Alveolar cell carcinoma Intellectual disability Headache Chronic obstructive pulmonary disease Cyanosis Generalized hypopigmentation Squamous cell carcinoma Failure to thrive Emphysema Sarcoma Pulmonary fibrosis Rectal prolapse Polycythemia Clubbing of fingers Hamartoma Tachypnea Abnormality of the liver Hepatomegaly Follicular thyroid carcinoma Fever Jaundice Papule Abdominal distention Lymphoma Increased body weight Precocious puberty Subcutaneous nodule Nasal polyposis Cafe-au-lait spot Nevus Hypothyroidism Cerebral calcification Dilatation Recurrent respiratory infections Hoarse voice Pneumothorax Thyroid carcinoma Meconium ileus Pancreatic adenocarcinoma Male infertility Bronchitis Exocrine pancreatic insufficiency Allergy Abnormality of the pancreas Productive cough Neoplasm of the pancreas Cor pulmonale Chronic lung disease Paraganglioma Chronic infection Chronic pancreatitis Ileus Obstructive lung disease Secretory diarrhea Biliary cirrhosis Nephrocalcinosis Steatorrhea Dyskinesia Testicular neoplasm Uterine leiomyoma Cardiac myxoma Profuse pigmented skin lesions Thyroid follicular hyperplasia Myxoid subcutaneous tumors Cutaneous myxoma Growth delay Immunodeficiency Recurrent infections Diabetes mellitus Malabsorption Delayed puberty Infertility Asthma Malnutrition Sinusitis Intestinal obstruction Hypercalciuria Azoospermia Pancreatitis Follicular hyperplasia Recurrent pneumonia Insulin resistance Decreased antibody level in blood Schwannoma Red hair Obstructive azoospermia Multiple lentigines Dehydration Pituitary prolactin cell adenoma Recurrent bronchopulmonary infections Attention deficit hyperactivity disorder Absent vas deferens Ependymoma Renal cell carcinoma Hyperventilation Skin tags Abnormality of the respiratory system Renal neoplasm White hair Wolff-Parkinson-White syndrome Brain neoplasm Astrocytoma Gingival fibromatosis Chylothorax Adenoma sebaceum Flank pain Shagreen patch Premature chromatid separation Nephroblastoma Cortical tubers Achromatic retinal patches Subungual fibromas Rhabdomyoma Connective tissue nevi Pulmonary lymphangiomyomatosis Chordoma Cardiac rhabdomyoma Renal angiomyolipoma Ungual fibroma Dental enamel pits Hypomelanotic macule Subependymal nodules Optic nerve glioma Angiofibromas Infantile spasms Aortic aneurysm Elevated sweat chloride Irritability Biliary tract obstruction Cellular metachromasia Echogenic fetal bowel Microscopic nephrocalcinosis Hydrocephalus Behavioral abnormality Intellectual disability, mild Renal insufficiency Arrhythmia Hyperactivity Glaucoma Autism Intellectual disability, moderate Abnormality of the kidney Autistic behavior Polycystic kidney dysplasia Focal-onset seizure CNS hypomyelination Hypoplasia of dental enamel Heterotopia Cardiomegaly Generalized-onset seizure Specific learning disability Brain atrophy Skin rash Gliosis Renal cyst Hypopigmentation of the skin Sleep disturbance Retinal detachment Abnormality of the cerebral white matter Pheochromocytoma Multiple gastric polyps Pituitary adenoma Cholestasis Interstitial pulmonary abnormality Exertional dyspnea Pulmonary infiltrates Right ventricular failure Pulmonary insufficiency Crackles Hypocapnia Reticular pattern on pulmonary HRCT Honeycomb lung Ground-glass opacification on pulmonary HRCT Hepatic failure Hepatitis Nephrotic syndrome Vasculitis Scaling skin Recurrent upper respiratory tract infections Hepatocellular carcinoma Neoplasm of the liver Panniculitis High palate Dysphagia Dystonia Absent speech Alopecia Hyperkeratosis Abnormality of the nervous system Aggressive behavior Memory impairment Increased antibody level in blood Pulmonary arterial hypertension Thick lower lip vermilion Hodgkin lymphoma Leukemia Neoplasm of the lung Lung adenocarcinoma Small cell lung carcinoma Non-small cell lung carcinoma Abnormality of metabolism/homeostasis Constipation Nausea and vomiting Ascites Melanoma Breast carcinoma Back pain Ovarian neoplasm Ovarian carcinoma Pneumonia Dysgerminoma Non-Hodgkin lymphoma Ovarian papillary adenocarcinoma Lymphadenopathy Aganglionic megacolon Goiter Amyloidosis Thyroiditis Neoplasm of the endocrine system Teratoma Papillary thyroid carcinoma Medullary thyroid carcinoma Cutaneous amyloidosis Respiratory insufficiency Abnormal blistering of the skin Thickened skin Macroorchidism Abnormality of the skin Hematemesis Melena Intussusception Duodenal adenocarcinoma Adenocarcinoma of the colon Hepatic vascular malformations Muscle weakness Osteoporosis Proximal muscle weakness Myalgia Abnormality of the eye Confusion Hirsutism Palpitations Stomach cancer Tall stature Gynecomastia Hemangioma Ischemic stroke Heart murmur Hypermelanotic macule Neurofibromas Macule Freckling Striae distensae Growth hormone excess Bipolar affective disorder Increased circulating cortisol level Blue irides Hamartomatous polyposis Intestinal polyposis Hallucinations Hoarse cry Oligodontia Oral-pharyngeal dysphagia Acne Fragile skin Alopecia of scalp Pustule Delusions Microglossia Verrucae Abnormal oral mucosa morphology Paranoia Patchy alopecia Abnormality of the gingiva Tongue nodules Hematochezia Bilateral intracranial calcifications Cryptorchidism Anemia Macrocephaly Hernia Umbilical hernia Vertigo Gastrointestinal hemorrhage Epistaxis Telangiectasia Diplopia Hypokalemia Hypoalbuminemia Colon cancer Projection of scalp hair onto lateral cheek



If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like Hepatomegaly and Chorea, related diseases and genetic alterations Macrocephaly and Constipation, related diseases and genetic alterations Hydrocephalus and Webbed neck, related diseases and genetic alterations Edema and Spinal muscular atrophy, related diseases and genetic alterations Flexion contracture and Osteoporosis, related diseases and genetic alterations Peripheral neuropathy and Gait ataxia, related diseases and genetic alterations

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