Breast carcinoma, and Hypotension

Diseases related with Breast carcinoma and Hypotension

In the following list you will find some of the most common rare diseases related to Breast carcinoma and Hypotension that can help you solving undiagnosed cases.


Top matches:

Medium match PEUTZ-JEGHERS SYNDROME; PJS


Peutz-Jeghers syndrome is an autosomal dominant disorder characterized by melanocytic macules of the lips, buccal mucosa, and digits; multiple gastrointestinal hamartomatous polyps; and an increased risk of various neoplasms.

PEUTZ-JEGHERS SYNDROME; PJS Is also known as polyps-and-spots syndrome|polyposis, hamartomatous intestinal

Related symptoms:

  • Neoplasm
  • Hypertension
  • Edema
  • Diarrhea
  • Headache


SOURCES: OMIM MENDELIAN

More info about PEUTZ-JEGHERS SYNDROME; PJS

Medium match WERNER SYNDROME


Werner syndrome (WS) is a rare inherited syndrome characterized by premature aging with onset in the third decade of life and with cardinal clinical features including bilateral cataracts, short stature, graying and thinning of scalp hair, characteristic skin disorders and premature onset of additional age-related disorders.

WERNER SYNDROME Is also known as ws|adult progeria

Related symptoms:

  • Short stature
  • Neoplasm
  • Pain
  • Cataract
  • Visual impairment


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about WERNER SYNDROME

Medium match SAETHRE-CHOTZEN SYNDROME


Saethre-Chotzen syndrome (SCS) is an inherited craniosynostosis syndrome characterized by unilateral or bilateral coronal synostosis, facial asymmetry, ptosis, strabismus and small ears with prominent crus, among other less common manifestations.

SAETHRE-CHOTZEN SYNDROME Is also known as acs3|acrocephalosyndactyly type 3|scs|acrocephaly, skull asymmetry, and mild syndactyly|acs iii|acrocephalosyndactyly, type iii|chotzen syndrome

Related symptoms:

  • Intellectual disability
  • Seizures
  • Global developmental delay
  • Short stature
  • Hearing impairment


SOURCES: OMIM ORPHANET MENDELIAN

More info about SAETHRE-CHOTZEN SYNDROME

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Other less relevant matches:

Medium match NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION


Neurofibromatosis type I is an autosomal dominant disorder characterized by cafe-au-lait spots, Lisch nodules in the eye, and fibromatous tumors of the skin. Individuals with the disorder have increased susceptibility to the development of benign and malignant tumors. NF1 is sometimes referred to as 'peripheral neurofibromatosis.' The worldwide incidence of NF1 is 1 in 2,500 to 1 in 3,000 individuals (reviews by Shen et al., 1996 and Williams et al., 2009).Type II neurofibromatosis (NF2 ) is a genetically distinct disorder caused by mutation in the gene encoding merlin (NF2 ) on chromosome 22q12. NF2, sometimes known as 'central neurofibromatosis,' is characterized by bilateral acoustic neuroma and meningioma, but few skin lesions or neurofibromas (Rouleau et al., 1993).Some patients with homozygous or compound heterozygous mutations in mismatch repair genes (see, e.g., MLH1; {120436} and MSH2; {609309}) have a phenotype characterized by early onset malignancies and mild features of NF1, especially cafe-au-lait spots; this is known as the mismatch repair cancer syndrome (OMIM ), sometimes referred to as brain tumor-polyposis syndrome-1 or Turcot syndrome. These patients typically do not have germline mutations in the NF1 gene, although a study by Wang et al. (2003) suggested that biallelic mutations in mismatch repair genes may cause somatic mutations in the NF1 gene, perhaps resulting in isolated features resembling NF1.See also Legius syndrome (OMIM ), a genetically distinct disorder with a similar phenotype to NF1.

NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION Is also known as von recklinghausen disease due to nf1 mutation or intragenic deletion|neurofibromatosis, peripheral type|von recklinghausen disease

Related symptoms:

  • Intellectual disability
  • Seizures
  • Short stature
  • Scoliosis
  • Hypertelorism


SOURCES: ORPHANET OMIM MENDELIAN

More info about NEUROFIBROMATOSIS TYPE 1 DUE TO NF1 MUTATION OR INTRAGENIC DELETION

Low match DOWN SYNDROME


Down syndrome is a chromosomal abnormality caused by the presence of a third (partial or total) copy of chromosome 21 and that is characterized by variable intellectual disability, muscular hypotonia, and joint laxity, often associated with a characteristic facial dysmorphism and various anomalies such as cardiac, gastrointestinal, or endocrine defects.

DOWN SYNDROME Is also known as trisomy 21

Related symptoms:

  • Intellectual disability
  • Global developmental delay
  • Short stature
  • Generalized hypotonia
  • Hearing impairment


SOURCES: ORPHANET MESH OMIM MENDELIAN

More info about DOWN SYNDROME

Low match CARNEY COMPLEX


Carney complex (CNC) is characterized by spotty skin pigmentation, endocrine overactivity and myxomas.

CARNEY COMPLEX Is also known as myxoma-spotty pigmentation-endocrine overactivity syndrome|carney syndrome|carney myxoma-endocrine complex, type 2

Related symptoms:

  • Neoplasm
  • Congestive heart failure
  • Stroke
  • Hirsutism
  • Sudden cardiac death


SOURCES: ORPHANET OMIM MENDELIAN

More info about CARNEY COMPLEX

Low match PANHYPOPITUITARISM


Insufficient production of all the anterior pituitary hormones.

PANHYPOPITUITARISM Is also known as pituitary dwarfism iv, formerly

Related symptoms:

  • Intellectual disability
  • Short stature
  • Growth delay
  • Fatigue
  • Delayed skeletal maturation


SOURCES: MESH ORPHANET OMIM MENDELIAN

More info about PANHYPOPITUITARISM

Low match ATYPICAL WERNER SYNDROME


Atypical Werner syndrome refers to a heterogeneous group of cases that are clinically diagnosed as Werner syndrome (WS; see this term) but do not carry WRN gene mutations. Similar to classical WS caused by WRN mutations, patients generally exhibit an aged appearance and common age-related disorders at earlier ages compared to the general population.

ATYPICAL WERNER SYNDROME Is also known as atypical progeroid syndrome

Related symptoms:

  • Short stature
  • Failure to thrive
  • Micrognathia
  • Hypertension
  • Skeletal muscle atrophy


SOURCES: ORPHANET MENDELIAN

More info about ATYPICAL WERNER SYNDROME

Low match OBESITY DUE TO LEPTIN RECEPTOR GENE DEFICIENCY


Deficiency or dysfunction of the leptin receptor, which is associated with loss-of-function mutation(s) in the LEPR gene.

OBESITY DUE TO LEPTIN RECEPTOR GENE DEFICIENCY Is also known as obesity, morbid, nonsyndromic 2

Related symptoms:

  • Intellectual disability
  • Obesity
  • Hypogonadism
  • Aggressive behavior
  • Delayed puberty


SOURCES: ORPHANET OMIM MENDELIAN

More info about OBESITY DUE TO LEPTIN RECEPTOR GENE DEFICIENCY

Low match PROLACTINOMA


Prolactinoma is a usually benign neoplasm of the pituitary gland that results in hyperprolactinemia. The most common clinical manifestations are amenorrhea and infertility in women; and impotence, decreased libido and infertility in men.

PROLACTINOMA Is also known as pituitary lactotrophic adenoma|prloma|prl-secreting pituitary adenoma|prolactin-secreting pituitary adenoma|lactotroph adenoma|prolactinoma, familial

Related symptoms:

  • Seizures
  • Neoplasm
  • Ptosis
  • Fatigue
  • Blindness


SOURCES: ORPHANET OMIM MENDELIAN

More info about PROLACTINOMA

Top 5 symptoms//phenotypes associated to Breast carcinoma and Hypotension

Symptoms // Phenotype % cases
Neoplasm Common - Between 50% and 80% cases
Short stature Common - Between 50% and 80% cases
Hypertension Common - Between 50% and 80% cases
Intellectual disability Uncommon - Between 30% and 50% cases
Osteoporosis Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Breast carcinoma and Hypotension. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Hypogonadism Ovarian neoplasm Neoplasm of the breast Delayed puberty Seizures Ptosis Meningioma Abnormal heart morphology Decreased fertility Type II diabetes mellitus Pituitary hypothyroidism Decreased testicular size Convex nasal ridge Leukemia Osteopenia Congestive heart failure Neoplasm of the endocrine system Prematurely aged appearance Abnormality of cardiovascular system morphology Gynecomastia Headache

Rare Symptoms - Less than 30% cases


Nevus Polyphagia Progeroid facial appearance Decreased circulating ACTH level Anemia Neoplasm of the lung Cognitive impairment Insulin-resistant diabetes mellitus Secondary amenorrhea Absence of secondary sex characteristics Telangiectasia of the skin Aplasia/Hypoplasia of the skin Lipoatrophy Accelerated skeletal maturation Depressed nasal ridge Premature graying of hair Renal neoplasm Microtia Rocker bottom foot Abnormality of the thorax Abnormality of the voice Mitral valve prolapse Hypogonadotrophic hypogonadism Sarcoma Laryngomalacia Amenorrhea Brachydactyly Aganglionic megacolon Cafe-au-lait spot Facial asymmetry Conductive hearing impairment Abnormality of the cerebral vasculature Osteosarcoma Neoplasm of the oral cavity Depressed nasal bridge Abnormality of the skeletal system Carcinoma Malar flattening Abnormal facial shape Blindness Strabismus Hypertelorism Scoliosis Hearing impairment Global developmental delay Hypoglycemia Hypertriglyceridemia Hydrocephalus Premature arteriosclerosis Flat face Neoplasm of the small intestine Subcutaneous calcification Abnormal hair whorl Soft tissue sarcoma Clinodactyly of the 5th finger Hyperinsulinemia Brachycephaly Thyroid carcinoma White forelock Abnormality of the testis Pili torti Chondrocalcinosis Lack of skin elasticity Peripheral arterial stenosis Hypergonadotropic hypogonadism Atherosclerosis Increased bone mineral density Parathyroid adenoma Behavioral abnormality Abnormality of the dentition Skeletal muscle atrophy Peripheral neuropathy Visual impairment Narrow face Pain Hypermelanotic macule Edema Uterine neoplasm Gastrointestinal carcinoma Neoplasm of the skin Narrow palate Testicular neoplasm Complete atrioventricular canal defect Growth hormone excess Pituitary adenoma Schwannoma Ovarian cyst Vestibular Schwannoma Neoplasm of the pancreas Abnormal prolactin level Renal cell carcinoma Pituitary prolactin cell adenoma Alopecia Cataract Diabetes mellitus Fatigue Abnormality of the hair Skin ulcer Short palm Abnormality of retinal pigmentation Decreased body weight Single transverse palmar crease Reduced bone mineral density Hypotrichosis Growth hormone deficiency Dilatation Epicanthus Bilateral single transverse palmar creases Proptosis Hyperkeratosis Retinal degeneration Obesity Stomach cancer Acute megakaryocytic leukemia Hypoplasia of the musculature Senile plaques Red hair Duodenal stenosis Multiple lentigines Brushfield spots Hypoplastic iliac wing Enlarged polycystic ovaries Left-to-right shunt Double outlet right ventricle Myeloproliferative disorder Abnormality of the lymphatic system Increased circulating cortisol level Prolactin excess Hypoxemia Stroke Hirsutism Short middle phalanx of the 5th finger Sudden cardiac death Atlantoaxial instability Pulmonary edema Subcutaneous nodule Crackles Shallow acetabular fossae Round ear Neutrophilia Acute monocytic leukemia Transient myeloproliferative syndrome Polycystic ovaries Colon cancer Abnormality of the fontanelles or cranial sutures Sudden loss of visual acuity Thickened nuchal skin fold Brow ptosis Narrow mouth Polydactyly Upslanted palpebral fissure Dementia Thrombocytopenia Recurrent infections Short nose Short neck Gait disturbance Myopia Muscular hypotonia Generalized hypotonia Tibial pseudoarthrosis Umbilical hernia Cerebral artery stenosis Arterial fibromuscular dysplasia Spinal neurofibromas Inguinal freckling Plexiform neurofibroma Acute promyelocytic leukemia Subcutaneous neurofibromas Optic nerve glioma Neurofibrosarcoma Neuroma Embryonal rhabdomyosarcoma Axillary freckling Renovascular hypertension Hypothyroidism Hydronephrosis Acute lymphoblastic leukemia Alzheimer disease Thrombocytosis Protruding tongue Polycythemia Neurofibrillary tangles Congenital hypothyroidism Impaired pain sensation Abnormality of immune system physiology Abnormality of blood and blood-forming tissues Transposition of the great arteries Broad palm Atrioventricular canal defect Thyroid adenoma Hydroureter Cholelithiasis Joint laxity Prolactinoma Renal hypoplasia/aplasia Sandal gap Open mouth Thick lower lip vermilion Microdontia Macroglossia Postural instability Neutropenia Downturned corners of mouth Postaxial polydactyly Anal atresia Developmental regression Adrenocortical carcinoma Anterior pituitary hypoplasia Pancreatic adenocarcinoma Sclerosis of hand bone Bitemporal hemianopia Decreased serum estradiol Immune dysregulation Emotional lability Impulsivity Recurrent upper respiratory tract infections Decreased fertility in males Erectile abnormalities Abnormality of the pituitary gland Primary amenorrhea Aggressive behavior Abnormality of circulating leptin level Patchy hypo- and hyperpigmentation Decreased proportion of CD4-positive T cells Progressive clavicular acroosteolysis Intervertebral disc degeneration Neoplasm of the thyroid gland Abnormality of the Achilles tendon Fasting hyperinsulinemia Aortic valve calcification Generalized lipodystrophy Abnormal hair quantity Abnormality of the pulmonary artery Exercise-induced myalgia Prominent superficial veins Osteolytic defects of the phalanges of the hand Decreased testosterone in males Orthostatic hypotension due to autonomic dysfunction Sparse body hair Easy fatigability Secondary growth hormone deficiency Galactorrhea Decreased fertility in females Abnormality of the menstrual cycle Oculomotor nerve palsy Hemianopia Menstrual irregularities Anterior hypopituitarism Adrenocorticotropic hormone deficiency Male hypogonadism Central adrenal insufficiency Impotence Cranial nerve paralysis Dyspareunia Diplopia Progressive visual loss Vertigo Nausea and vomiting Pallor Vomiting Abnormal hypothalamus morphology Decreased T cell activation Decreased serum leptin Adrenocorticotropin deficient adrenal insufficiency Hypoplasia of the ovary Female hypogonadism Fragile nails Glycosuria Osteochondroma Profuse pigmented skin lesions Hypopituitarism Infertility Constipation Delayed skeletal maturation Growth delay Intra-oral hyperpigmentation Abnormality of circulating adrenocorticotropin level Thyroid follicular hyperplasia Sertoli cell neoplasm Pigmentation of the sclera Abnormal pigmentation of the oral mucosa Peripheral Schwannoma Blue nevus Abnormality of hair density Hepatocellular adenoma Pigmented micronodular adrenocortical disease Cardiac myxoma Histiocytoma Bronchogenic cyst Hypertension associated with pheochromocytoma Nodular goiter Fibroadenoma of the breast Increased urinary cortisol level Adrenal pheochromocytoma Pituitary growth hormone cell adenoma Recurrent paroxysmal headache Neonatal hypoglycemia Panhypopituitarism Aplasia/Hypoplasia of the eyebrow Thin vermilion border Coronary artery atherosclerosis Calf muscle hypertrophy Hyperglycemia Premature ovarian insufficiency Finger clinodactyly Aortic valve stenosis Thin skin Cranial nerve VI palsy Fourth cranial nerve palsy Hip dysplasia Limitation of joint mobility Hepatic steatosis Congenital cataract Gonadotropin deficiency Pes planus Micrognathia Failure to thrive Single ventricle Ectopic anterior pituitary gland Abnormality of secondary sexual hair Internal ophthalmoplegia Osteoporosis of vertebrae Aplasia/Hypoplasia of the breasts Pituitary dwarfism Ectopic posterior pituitary Decreased female libido Renal artery stenosis Abnormality of skin pigmentation Pseudoarthrosis Chorioretinitis Midface retrusion Syndactyly Optic atrophy Flexion contracture Low-set ears Cryptorchidism Cleft palate Sensorineural hearing impairment Microcephaly Acral lentiginous melanoma Aplasia/Hypoplasia of the testes Poliosis Cutaneous melanoma Posteriorly rotated ears Narrow nasal ridge Arteriosclerosis Enlarged joints Slender build Posterior subcapsular cataract Pulmonary artery stenosis Alopecia of scalp Premature loss of teeth Subcapsular cataract Myeloid leukemia Scleroderma High pitched voice Clinodactyly Mandibular prognathia Polyuria Dental malocclusion Abnormality of the genitourinary system Increased intracranial pressure Sleep apnea Cutaneous syndactyly Plagiocephaly Coxa valga Elbow flexion contracture Low anterior hairline Amblyopia Broad thumb Abnormal form of the vertebral bodies Hypotelorism Migraine High forehead Hypoplasia of the maxilla Toe syndactyly Finger syndactyly Broad forehead Prominent nasal bridge Craniosynostosis Protruding ear Hyperlordosis Low-set, posteriorly rotated ears Cleft lip Intellectual disability, moderate Telecanthus Squamous cell carcinoma Polydipsia Radioulnar synostosis Hamartoma Hamartomatous polyposis Nasal polyposis Rectal prolapse Biliary tract abnormality Pancreatic cysts Intestinal polyposis Multiple myeloma Clubbing of fingers Abnormality of the mouth Vitiligo Abnormality of the ureter Iron deficiency anemia Macule Hematemesis Intestinal obstruction Clubbing Melanocytic nevus Psoriasiform dermatitis Polycystic kidney dysplasia Growth abnormality Hemangioma Abdominal distention Abnormality of the kidney Abdominal pain Hyperhidrosis Diarrhea Intestinal bleeding Thrombophlebitis Myelodysplasia Hypopigmentation of the skin Lipodystrophy Dermal atrophy Melanoma Macular degeneration Type I diabetes mellitus Spontaneous abortion Hoarse voice Insulin resistance Sparse scalp hair Myocardial infarction Chest pain Coma Small hand Bloody diarrhea Nephropathy Retinopathy Joint stiffness Micropenis Rod-cone dystrophy Precocious puberty with Sertoli cell tumor Endolymphatic sac tumor Congenital shortened small intestine Thyroid nodule Clear cell renal cell carcinoma Intussusception Intestinal polyp Abnormality of pelvic girdle bone morphology Trigonocephaly Epigastric pain Abnormality of the cardiovascular system Hypophosphatemia Sensory axonal neuropathy Clitoral hypertrophy Precocious puberty Back pain Incoordination Venous thrombosis Spina bifida Sensorimotor neuropathy Bone pain Hypsarrhythmia Coarctation of aorta Tetralogy of Fallot Neurofibromas Overgrowth Specific learning disability Gastrointestinal hemorrhage Lymphoma Recurrent fractures Peripheral axonal neuropathy Paresthesia Genu valgum Malabsorption Pulmonic stenosis Pruritus Attention deficit hyperactivity disorder Pulmonary fibrosis Tibial bowing Autistic behavior Paraganglioma Dural ectasia Leiomyosarcoma Fibular bowing Gastrointestinal stroma tumor Neoplasm of the central nervous system Lisch nodules Chronic myelogenous leukemia Renal phosphate wasting Glioma Nasolacrimal duct obstruction Rhabdomyosarcoma Carcinoid tumor Night sweats Freckling Anomalous pulmonary venous return Pheochromocytoma Aqueductal stenosis Astrocytoma Brain neoplasm Myocardial fibrosis Gangrene Increased reactive oxygen species production Overweight Severe vision loss Osteomalacia Multiple cafe-au-lait spots Paralysis Hypertrophic cardiomyopathy Triphalangeal thumb Coronal craniosynostosis Craniofacial dysostosis Lacrimal duct stenosis Lambdoidal craniosynostosis Anterior plagiocephaly Oxycephaly Buphthalmos Abnormal hair pattern Bilateral cleft lip and palate Adrenal hyperplasia Blepharospasm Abnormality of the antihelix Short columella Abnormality of the skull Parietal foramina Bilateral cleft lip Shallow orbits Narrow nose External ear malformation Abnormality of digit Vertebral fusion Long nose Delayed cranial suture closure Broad hallux Hallux valgus Open bite Epiphora Congenital adrenal hyperplasia Abnormal nasolacrimal system morphology Kyphoscoliosis Cleft of chin Autism Weight loss Glaucoma Hyperactivity Visual loss Depressivity Intellectual disability, mild Cardiomyopathy Respiratory insufficiency Macrocephaly Dysarthria Delayed speech and language development Absent first metatarsal Flat forehead Partial duplication of the distal phalanx of the 2nd finger Partial duplication of the distal phalanx of the 3rd finger Renotubular dysgenesis Prominent crus of helix Proximal radio-ulnar synostosis Premature closure of fontanelles Duplication of the distal phalanx of hand Deviated nasal septum Skull asymmetry Narrow internal auditory canal Mild hearing impairment Craniofacial asymmetry Adrenogenital syndrome Heteronymous hemianopia



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