Autoimmunity, and Pheochromocytoma

Diseases related with Autoimmunity and Pheochromocytoma

In the following list you will find some of the most common rare diseases related to Autoimmunity and Pheochromocytoma that can help you solving undiagnosed cases.


Top matches:

Low match PARAGANGLIOMAS 5; PGL5


Related symptoms:

  • Neoplasm
  • Hypertension
  • Hyperhidrosis
  • Vertigo
  • Tachycardia


SOURCES: OMIM MENDELIAN

More info about PARAGANGLIOMAS 5; PGL5

Low match MULTIPLE ENDOCRINE NEOPLASIA TYPE 4


Multiple endocrine neoplasia type 4 (MEN4) is a very rare form of MEN (see this term), an inherited cancer syndrome, characterized by parathyroid and anterior pituitary tumors, possibly associated with adrenal, renal, and reproductive organ tumors.

MULTIPLE ENDOCRINE NEOPLASIA TYPE 4 Is also known as men4

Related symptoms:

  • Neoplasm
  • Hypertension
  • Diarrhea
  • Diabetes mellitus
  • Hypothyroidism


SOURCES: OMIM MESH ORPHANET MENDELIAN

More info about MULTIPLE ENDOCRINE NEOPLASIA TYPE 4

Low match MULTIPLE ENDOCRINE NEOPLASIA TYPE 1


Multiple endocrine neoplasia Type 1 (MEN1) is a frequent form of MEN (see this term), a rare inherited cancer syndrome, characterized by the development of neuroendocrine tumors of the parathyroid, pancreas, and anterior pituitary gland, and less commonly the adrenal cortical gland, with other non-endocrine tumors in some patients.

MULTIPLE ENDOCRINE NEOPLASIA TYPE 1 Is also known as men1|wermer syndrome|endocrine adenomatosis, multiple|mea i|men i

Related symptoms:

  • Seizures
  • Neoplasm
  • Pain
  • Vomiting
  • Diarrhea


SOURCES: OMIM ORPHANET MENDELIAN

More info about MULTIPLE ENDOCRINE NEOPLASIA TYPE 1

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Other less relevant matches:

Low match PARAGANGLIOMAS 3; PGL3


PARAGANGLIOMAS 3; PGL3 Is also known as glomus tumors, familial, 3

Related symptoms:

  • Hyperhidrosis
  • Tachycardia
  • Palpitations
  • Hoarse voice
  • Cranial nerve paralysis


SOURCES: OMIM MENDELIAN

More info about PARAGANGLIOMAS 3; PGL3

Low match MULTIPLE ENDOCRINE NEOPLASIA, TYPE IIA; MEN2A


Multiple endocrine neoplasia type IIA is an autosomal dominant syndrome of multiple endocrine neoplasms, including medullary thyroid carcinoma (MTC), pheochromocytoma, and parathyroid adenomas. MEN2B (OMIM ), characterized by MTC with or without pheochromocytoma and with characteristic clinical abnormalities such as ganglioneuromas of the lips, tongue and colon, but without hyperparathyroidism, is also caused by mutation in the RET gene (summary by Lore et al., 2001).For a discussion of genetic heterogeneity of multiple endocrine neoplasia, see MEN1 (OMIM ).

MULTIPLE ENDOCRINE NEOPLASIA, TYPE IIA; MEN2A Is also known as pheochromocytoma and amyloid-producing medullary thyroid carcinoma|sipple syndrome|ptc syndrome

Related symptoms:

  • Neoplasm
  • Hypertension
  • Carcinoma
  • Aganglionic megacolon
  • Hyperparathyroidism


SOURCES: OMIM MENDELIAN

More info about MULTIPLE ENDOCRINE NEOPLASIA, TYPE IIA; MEN2A

Low match COWDEN SYNDROME 7; CWS7


Related symptoms:

  • Neoplasm
  • Macrocephaly
  • Papule
  • Neoplasm of the skin
  • Hemangioma


SOURCES: OMIM MENDELIAN

More info about COWDEN SYNDROME 7; CWS7

Low match CARNEY TRIAD


Carney's triad is a rare non-hereditary condition characterized by gastrointestinal stromal tumors (GIST, intramural mesenchymal tumors of the gastrointestinal tract with neuronal or neural crest cell origin), pulmonary chondromas and extraadrenal paragangliomas.

CARNEY TRIAD Is also known as gastric leiomyosarcoma, pulmonary chondroma, and extraadrenal paraganglioma

Related symptoms:

  • Anemia
  • Hypertension
  • Fatigue
  • Diarrhea
  • Headache


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about CARNEY TRIAD

Low match PARAGANGLIOMAS 4; PGL4


PARAGANGLIOMAS 4; PGL4 Is also known as paraganglioma, familial malignant|pheochromocytoma, extraadrenal, and cervical paraganglioma|carotid body tumors and multiple extraadrenal pheochromocytomas|pheochromocytoma, familial extraadrenal|paragangliomas, hereditary extraadrenal

Related symptoms:

  • Neoplasm
  • Pain
  • Hypertension
  • Congestive heart failure
  • Headache


SOURCES: OMIM MENDELIAN

More info about PARAGANGLIOMAS 4; PGL4

Low match TESTICULAR TERATOMA


Testicular germ cell tumors (TGCTs) affect 1 in 500 men and are the most common cancer in males aged 15 to 40 in western European populations. The incidence of TGCT rose dramatically during the 20th century. Known risk factors for TGCT include a history of undescended testis (UDT), testicular dysgenesis, infertility, previously diagnosed TGCT, and a family history of the disease. Brothers of men with TGCT have an 8- to 10-fold risk of developing TGCT, whereas the relative risk to fathers and sons is 4-fold. This familial relative risk is much higher than that for most other types of cancer (summary by Rapley et al., 2000). Genetic Heterogeneity of Testicular Germ Cell TumorsA locus for testicular germ cell tumors (TGCT1 ) has been identified on chromosome Xq27.

TESTICULAR TERATOMA Is also known as male germ cell tumor|mgct|teratoma of the testis

Related symptoms:

  • Neoplasm
  • Cryptorchidism
  • Hydrocephalus
  • Abnormality of metabolism/homeostasis
  • Carcinoma


SOURCES: OMIM ORPHANET MENDELIAN

More info about TESTICULAR TERATOMA

Low match VON HIPPEL-LINDAU SYNDROME; VHL


Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign neoplasms, most frequently retinal, cerebellar, and spinal hemangioblastoma, renal cell carcinoma (RCC), pheochromocytoma, and pancreatic tumors.Neumann and Wiestler (1991) classified VHL as type 1 (without pheochromocytoma) and type 2 (with pheochromocytoma). Brauch et al. (1995) further subdivided VHL type 2 into type 2A (with pheochromocytoma) and type 2B (with pheochromocytoma and renal cell carcinoma). Hoffman et al. (2001) noted that VHL type 2C refers to patients with isolated pheochromocytoma without hemangioblastoma or renal cell carcinoma. McNeill et al. (2009) proposed that patients with VHL syndrome caused by large VHL deletions that include the HSPC300 gene (C3ORF10 ) have a specific subtype of VHL syndrome characterized by protection from renal cell carcinoma, which the authors proposed be named VHL type 1B.Nordstrom-O'Brien et al. (2010) provided a review of the genetics of von Hippel-Lindau disease.

Related symptoms:

  • Hearing impairment
  • Neoplasm
  • Sensorineural hearing impairment
  • Pain
  • Hypertension


SOURCES: OMIM MENDELIAN

More info about VON HIPPEL-LINDAU SYNDROME; VHL

Top 5 symptoms//phenotypes associated to Autoimmunity and Pheochromocytoma

Symptoms // Phenotype % cases
Neoplasm Common - Between 50% and 80% cases
Hypertension Common - Between 50% and 80% cases
Carcinoma Common - Between 50% and 80% cases
Paraganglioma Uncommon - Between 30% and 50% cases
Tachycardia Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Autoimmunity and Pheochromocytoma. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Carcinoid tumor Neoplasm of the endocrine system Hyperparathyroidism Pain Adrenocortical adenoma Parathyroid hyperplasia Parathyroid adenoma Increased circulating cortisol level Adrenal pheochromocytoma Hypercalcemia Hyperhidrosis Diarrhea

Rare Symptoms - Less than 30% cases


Abnormality of pancreas physiology Pituitary corticotropic cell adenoma Recurrent paroxysmal headache Pituitary null cell adenoma Angiofibromas Insulinoma Palpitations Increased glucagon level Renal cell carcinoma Confetti-like hypopigmented macules Pulsatile tinnitus Abnormality of the thyroid gland Vertigo Episodic paroxysmal anxiety Abdominal pain Hypertension associated with pheochromocytoma Hydrocephalus Chemodectoma Hemangioma Papule Extraadrenal pheochromocytoma Glomus jugular tumor Neoplasm of the pancreas Hyperaldosteronism Pituitary growth hormone cell adenoma Increased urinary cortisol level Zollinger-Ellison syndrome Thyroid adenoma Growth hormone excess Hashimoto thyroiditis Cranial nerve paralysis Episodic abdominal pain Esophagitis Pituitary adenoma Hyperinsulinemic hypoglycemia Abnormality of the endocrine system Gastrointestinal stroma tumor Elevated circulating parathyroid hormone level Erythema Thyroid carcinoma Primary hyperparathyroidism Peptic ulcer Headache Thymoma Papillary thyroid carcinoma Pituitary prolactin cell adenoma Testicular neoplasm Extrahepatic cholestasis Subcutaneous lipoma Fasting hyperinsulinemia Neuroendocrine neoplasm Neuroma Vestibular Schwannoma Dysgerminoma Testicular dysgenesis Neuroblastoma Teratoma Retinoblastoma Gonadal dysgenesis Male infertility Colon cancer Azoospermia Infertility Abnormality of metabolism/homeostasis Cryptorchidism Elevated urinary catecholamines Paraganglioma of head and neck Anxiety Congestive heart failure Adrenal overactivity Leiomyosarcoma Choriocarcinoma Hamartoma Testicular microlithiasis Retinal neovascularization Capillary hemangioma Renal neoplasm Facial paralysis Pancreatic cysts Choroidal neovascularization Posterior uveitis Epididymal cyst Papilledema Papillary cystadenoma of the epididymis Retinal capillary hemangioma Cerebellar hemangioblastoma Pulmonary capillary hemangiomatosis Hemangioblastoma Spinal hemangioblastoma Secondary hyperaldosteronism Multiple renal cysts Subarachnoid hemorrhage Testicular teratoma Retinal detachment Hearing impairment Sensorineural hearing impairment Edema Blindness Dilatation Visual loss Abnormality of the liver Renal cyst Exocrine pancreatic insufficiency Nevus Progressive visual loss Tinnitus Hypokalemia Neurofibromas Pulmonary infiltrates Polycythemia Mediastinal lymphadenopathy Elevated circulating catecholamine level Anorexia Cafe-au-lait spot Epigastric pain Adenoma sebaceum Schwannoma Bone cyst Peritonitis Prolactin excess Lipoma Multiple lipomas Steatorrhea Glucose intolerance Intestinal obstruction Pyloric stenosis Elevated alkaline phosphatase Nausea Neurofibrosarcoma Skin rash Scarring Hypoglycemia Weight loss Vomiting Seizures Cervix cancer Pulmonary carcinoid tumor Renal angiomyolipoma Parathyroid carcinoma Diabetes mellitus Hypothyroidism Type II diabetes mellitus Abnormality of the urinary system Adrenocortical carcinoma Abnormality of the anterior pituitary Gastrointestinal hemorrhage Neoplasm of the skin Ascites Lymphadenopathy Nausea and vomiting Arrhythmia Fatigue Anemia Ductal carcinoma in situ Trichilemmoma Fibroadenoma of the breast Papilloma Intestinal polyposis Goiter Breast carcinoma Macrocephaly Anterior pituitary dysgenesis Abnormality of the integument Elevated urinary epinephrine Elevated calcitonin Medullary thyroid carcinoma Upper limb undergrowth Aganglionic megacolon Thyroiditis Loss of voice Vocal cord paralysis Hoarse voice Pancreatic endocrine tumor Pancreatic islet cell adenoma Prolactinoma Glucagonoma Neoplasm of the ear



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