Arthritis, and Bradycardia

Diseases related with Arthritis and Bradycardia

In the following list you will find some of the most common rare diseases related to Arthritis and Bradycardia that can help you solving undiagnosed cases.


Top matches:

Low match FABRY DISEASE


Fabry disease (FD) is a progressive, inherited, multisystemic lysosomal storage disease characterized by specific neurological, cutaneous, renal, cardiovascular, cochleo-vestibular and cerebrovascular manifestations.

FABRY DISEASE Is also known as ceramide trihexosidase deficiency|hereditary dystopic lipidosis|fd|alpha-galactosidase a deficiency|diffuse angiokeratoma|gla deficiency|angiokeratoma corporis diffusum|anderson-fabry disease

Related symptoms:

  • Seizures
  • Short stature
  • Hearing impairment
  • Sensorineural hearing impairment
  • Pain


SOURCES: ORPHANET OMIM MESH MENDELIAN

More info about FABRY DISEASE

Low match EMERY-DREIFUSS MUSCULAR DYSTROPHY 7, AUTOSOMAL DOMINANT; EDMD7


Emery-Dreifuss muscular dystrophy is a genetically heterogeneous muscular disease that presents with muscular dystrophy, joint contractures, and cardiomyopathy with conduction defects (summary by Liang et al., 2011).For a discussion of genetic heterogeneity of EDMD, see {310300}.

Related symptoms:

  • Muscle weakness
  • Flexion contracture
  • Cardiomyopathy
  • Arrhythmia
  • Proximal muscle weakness


SOURCES: OMIM MENDELIAN

More info about EMERY-DREIFUSS MUSCULAR DYSTROPHY 7, AUTOSOMAL DOMINANT; EDMD7

Low match ATRIAL SEPTAL DEFECT 6; ASD6


Related symptoms:

  • Atrial septal defect
  • Atrial fibrillation
  • Bradycardia


SOURCES: OMIM MESH MENDELIAN

More info about ATRIAL SEPTAL DEFECT 6; ASD6

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Other less relevant matches:

Low match SINOATRIAL NODE DYSFUNCTION AND DEAFNESS


Sinoatrial node dysfunction and deafness is a rare genetic disease characterized by congenital severe to profound deafness with no evidence of vestibular dysfunction, associated with sinoatrial node dysfunction with pronounced bradycardia and increased variability of heart rate at rest and episodic syncopes that may be triggered by enhanced physical activity and stress.

Related symptoms:

  • Hearing impairment
  • Syncope
  • Bradycardia
  • Vestibular dysfunction
  • Abnormal atrioventricular conduction


SOURCES: OMIM ORPHANET MENDELIAN

More info about SINOATRIAL NODE DYSFUNCTION AND DEAFNESS

Low match ATRIAL FIBRILLATION, FAMILIAL, 18; ATFB18


Related symptoms:

  • Arrhythmia
  • Atrial fibrillation
  • Palpitations
  • Bradycardia
  • Sinus bradycardia


SOURCES: OMIM MENDELIAN

More info about ATRIAL FIBRILLATION, FAMILIAL, 18; ATFB18

Low match SHORT QT SYNDROME 2; SQT2


Short QT syndrome is a cardiac channelopathy associated with a predisposition to atrial fibrillation and sudden cardiac death. Patients have a structurally normal heart, but electrocardiography (ECG) exhibits abbreviated QTc (Bazett's corrected QT) intervals of less than 360 ms (summary by Moreno et al., 2015).For a discussion of genetic heterogeneity of short QT syndrome, see SQT1 (OMIM ).

Related symptoms:

  • Arrhythmia
  • Sudden cardiac death
  • Syncope
  • Atrial fibrillation
  • Bradycardia


SOURCES: OMIM MESH MENDELIAN

More info about SHORT QT SYNDROME 2; SQT2

Low match CARDIAC ARRHYTHMIA, ANKYRIN-B-RELATED


Loss-of-function mutations in ANK2 can result in a broad spectrum of clinical cardiac phenotypes. Carriers of some mutations (e.g., E1425G, {106410.0001}) display QT interval prolongation, stress- and/or exercise-induced polymorphic ventricular arrhythmia, syncope, and sudden cardiac death. Patients with other variants show clinical phenotypes, sometimes mild, extending beyond LQTS, leading to the label 'ankyrin-B syndrome.' These phenotypes include bradycardia, sinus arrhythmia, delayed conduction/conduction block, idiopathic ventricular fibrillation, and catecholaminergic polymorphic ventricular tachycardia (Mohler et al., 2007).

CARDIAC ARRHYTHMIA, ANKYRIN-B-RELATED Is also known as ankyrin-b syndrome

Related symptoms:

  • Arrhythmia
  • Tachycardia
  • Sudden cardiac death
  • Syncope
  • Atrial fibrillation


SOURCES: OMIM MENDELIAN

More info about CARDIAC ARRHYTHMIA, ANKYRIN-B-RELATED

Low match VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 2; CPVT2


VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 2; CPVT2 Is also known as ventricular tachycardia, stress-induced polymorphic|vtsip

Related symptoms:

  • Seizures
  • Tachycardia
  • Syncope
  • Bradycardia
  • Ventricular tachycardia


SOURCES: OMIM MENDELIAN

More info about VENTRICULAR TACHYCARDIA, CATECHOLAMINERGIC POLYMORPHIC, 2; CPVT2

Low match LONG QT SYNDROME 9; LQT9


Congenital long QT syndrome is electrocardiographically characterized by a prolonged QT interval and polymorphic ventricular arrhythmias (torsade de pointes). These cardiac arrhythmias may result in recurrent syncope, seizure, or sudden death (Jongbloed et al., 1999).For a discussion of genetic heterogeneity of long QT syndrome, see LQT1 (OMIM ).

LONG QT SYNDROME 9; LQT9 Is also known as long qt syndrome 2/9, digenic, included|long qt syndrome 9, acquired, susceptibility to, included|lqt2/9, digenic, included

Related symptoms:

  • Seizures
  • Arrhythmia
  • Syncope
  • Cardiac arrest
  • Ventricular arrhythmia


SOURCES: MESH OMIM MENDELIAN

More info about LONG QT SYNDROME 9; LQT9

Low match ROMANO-WARD SYNDROME


Romano-Ward syndrome (RWS) is an autosomal dominant variant of the long QT syndrome (LQTS, see this term) characterized by syncopal episodes and electrocardiographic abnormalities (QT prolongation, T-wave abnormalities and torsade de pointes (TdP) ventricular tachycardia).

ROMANO-WARD SYNDROME Is also known as romano-ward long qt syndrome

Related symptoms:

  • Seizures
  • Arrhythmia
  • Sudden cardiac death
  • Syncope
  • Bradycardia


SOURCES: ORPHANET OMIM MENDELIAN

More info about ROMANO-WARD SYNDROME

Top 5 symptoms//phenotypes associated to Arthritis and Bradycardia

Symptoms // Phenotype % cases
Syncope Common - Between 50% and 80% cases
Arrhythmia Common - Between 50% and 80% cases
Atrial fibrillation Common - Between 50% and 80% cases
Sinus bradycardia Uncommon - Between 30% and 50% cases
Sudden cardiac death Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Arthritis and Bradycardia. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Ventricular tachycardia Ventricular arrhythmia Seizures Ventricular fibrillation Tachycardia Prolonged QT interval

Rare Symptoms - Less than 30% cases


Hearing impairment Cardiomyopathy Cardiac arrest Polymorphic ventricular tachycardia Palpitations Atrial arrhythmia Atrioventricular block Torsade de pointes Shortened QT interval Renal tubular acidosis Asymmetric septal hypertrophy Abnormal mitral valve morphology Periorbital fullness Gastrointestinal dysmotility Abnormal aortic valve morphology T-wave inversion Chronic pain Miosis Abnormal renal physiology Primary hypothyroidism Tubulointerstitial fibrosis Abnormal thrombosis Abnormality of the renal tubule Abnormal cornea morphology Dysesthesia Glycosuria Supraventricular arrhythmia Conjunctival telangiectasia Microalbuminuria High-frequency hearing impairment Abnormality of femur morphology Abnormal myocardium morphology Oligospermia Aortic root aneurysm Abnormality of lipid metabolism Abnormal EKG Xerostomia Transient ischemic attack Renal tubular dysfunction Edema of the lower limbs Tubulointerstitial nephritis Elevated serum creatinine Tubular atrophy Abnormality of the gastrointestinal tract Large earlobe Restrictive cardiomyopathy Supraventricular tachycardia Heat intolerance Reduced ejection fraction Peripheral arterial stenosis Clubbing of fingers Angina pectoris Chronic obstructive pulmonary disease Biventricular hypertrophy Myocardial fibrosis Chronic fatigue Wheezing Abnormality of the nose Achalasia Corneal crystals Abnormal endocardium morphology Flexion contracture Left ventricular septal hypertrophy Tenesmus Heavy proteinuria Acroparesthesia Abnormal common carotid artery morphology Abnormal ST segment Increased carotid artery intimal medial thickness Increased glomerular filtration rate Abnormality of the common coagulation pathway Abnormal glomerular filtration rate Cornea verticillata Muscle weakness Proximal muscle weakness Hyperkeratotic papule Muscular dystrophy Progressive muscle weakness Neck muscle weakness Proximal amyotrophy Atrial septal defect Vestibular dysfunction Abnormal atrioventricular conduction Abnormal electrophysiology of sinoatrial node origin Paroxysmal atrial fibrillation Permanent atrial fibrillation Epileptic spasms Abnormal T-wave Tortuosity of conjunctival vessels Abnormality of the forehead Abnormality of cardiovascular system physiology Angiokeratoma Decreased female libido Vascular skin abnormality Retinal vascular tortuosity Glomerulopathy Limb pain Abnormality of temperature regulation Nephrogenic diabetes insipidus Decreased glomerular filtration rate Vascular tortuosity Distal renal tubular acidosis Increased blood urea nitrogen Reduced sperm motility Obstructive lung disease Abnormality of glycosphingolipid metabolism Impaired temperature sensation Hyposthenuria Angiokeratoma corporis diffusum Decreased lacrimation Shortened PR interval Coronary artery stenosis Concentric hypertrophic cardiomyopathy Mucosal telangiectasiae Unexplained fevers ST segment depression Functional abnormality of the gastrointestinal tract Impaired renal concentrating ability Abnormal heart valve morphology Coronary artery atherosclerosis Telangiectasia of the skin Cough Coarse facial features Myalgia Carcinoma Anxiety Proteinuria Abnormality of the nervous system Hypertrophic cardiomyopathy Abnormality of the kidney Developmental regression Skin rash Stroke Prominent nasal bridge Mandibular prognathia Corneal opacity Papule Pruritus Abnormality of the cerebral white matter Malabsorption Nausea and vomiting Delayed puberty Paresthesia Vertigo Stage 5 chronic kidney disease Nausea Bulbous nose Arthralgia Dyspnea Thick vermilion border Vomiting Sensorineural hearing impairment Pain Cataract Cognitive impairment Anemia Hypertension Peripheral neuropathy Fever Optic atrophy Fatigue Respiratory insufficiency Edema Diarrhea Hypothyroidism Congestive heart failure Behavioral abnormality Renal insufficiency Headache Dilatation Midface retrusion Depressivity Constipation Posteriorly rotated ears Hyperhidrosis Abdominal pain Hyperkeratosis Thick eyebrow Hematuria Celiac disease Impaired vibratory sensation Reduced bone mineral density Tinnitus Easy fatigability Chronic kidney disease Prominent supraorbital ridges Abnormality of the hand Hemiplegia Glomerulosclerosis Polydipsia Personality changes Heart murmur Clubbing Tricuspid regurgitation Corneal dystrophy Diabetes insipidus Polyuria Anhidrosis Emphysema Loss of consciousness Bundle branch block Impotence Short stature Elevated erythrocyte sedimentation rate Interstitial pulmonary abnormality Progressive sensorineural hearing impairment Orthostatic hypotension Ischemic stroke Progressive hearing impairment Nephropathy Abnormal lung morphology Muscle cramps Abdominal distention Chest pain Urinary incontinence Hypotension Abnormality of the cardiovascular system Mitral valve prolapse Nephrotic syndrome Ventricular hypertrophy Thick lower lip vermilion Myocardial infarction Mitral regurgitation Subcutaneous nodule Abnormal intestine morphology Left ventricular hypertrophy Anorexia Hypohidrosis Lymphedema Fasciculations Abnormal autonomic nervous system physiology Spontaneous abortion Exercise intolerance Aminoaciduria Purpura Hyperlipidemia Aortic regurgitation T-wave alternans



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