Anemia, and Amyotrophic lateral sclerosis

Diseases related with Anemia and Amyotrophic lateral sclerosis

In the following list you will find some of the most common rare diseases related to Anemia and Amyotrophic lateral sclerosis that can help you solving undiagnosed cases.


Top matches:

Low match AMYOTROPHIC LATERAL SCLEROSIS 23; ALS23


Related symptoms:

  • Dementia
  • Pallor
  • Neuronal loss in central nervous system
  • Amyotrophic lateral sclerosis


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 23; ALS23

Low match AMYOTROPHIC LATERAL SCLEROSIS 22 WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA; ALS22


Related symptoms:

  • Dementia
  • Mental deterioration
  • Amyotrophic lateral sclerosis
  • Frontotemporal dementia
  • Abnormal lower motor neuron morphology


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 22 WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA; ALS22

Low match AMYOTROPHIC LATERAL SCLEROSIS 20; ALS20


Related symptoms:

  • Muscular dystrophy
  • Elevated alkaline phosphatase
  • Amyotrophic lateral sclerosis
  • Rimmed vacuoles
  • Muscle fiber inclusion bodies


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 20; ALS20

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Other less relevant matches:

Low match AMYOTROPHIC LATERAL SCLEROSIS 11; ALS11


Related symptoms:

  • Skeletal muscle atrophy
  • Amyotrophic lateral sclerosis
  • Bulbar signs
  • Upper motor neuron dysfunction


SOURCES: OMIM MESH MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 11; ALS11

Low match BLOOD GROUP, SS; SS


Ss blood group antigens reside on the red-cell glycoprotein GYPB. The S and s antigens result from a polymorphism at amino acid 29 of GYPB, where S has met29 and s has thr29. The U antigen refers to a short extracellular sequence in GYPB located near the membrane. GYPB, glycophorin A (GYPA ), and glycophorin E (GYPE ) are closely linked on chromosome 4q31. Antigens of the MN blood group (OMIM ) reside on GYPA. The M and N antigens differ at amino acids 1 and 5 of GYPA, where M is ser-ser-thr-thr-gly, and N is leu-ser-thr-thr-glu. The N terminus of GYPB is essentially identical to that of GYPA except that it always expresses the N antigen, denoted 'N' or N-prime. Recombination and gene conversion between GYPA, GYPB, and GYPE lead to hybrid glycophorin molecules and generation of low-incidence antigens. Thus, the MN and Ss blood groups are together referred to as the MNSs blood group system (see {111300}). Recombination results in 3 glycophorin-null phenotypes: En(a-) cells lack GYPA due to recombination between GYPA and GYPB; GYPB-negative (S-s-U-) cells lack GYPB due to recombination in GYPB; and M(k) cells (M-N-S-s-U-) lack both GYPA and GYPB due to recombination between GYPA and GYPE. Individuals with glycophorin-null phenotypes have decreased sialic acid content and increased resistance to malarial infection (see {611162}). GYPA and GYPB are not essential for red-cell development or survival, and GYPA- and GYPB-null phenotypes are not associated with anemia or altered red-cell function (review by Cooling, 2015).

BLOOD GROUP, SS; SS Is also known as ss blood group

Related symptoms:

  • Neoplasm
  • Anemia


SOURCES: OMIM MENDELIAN

More info about BLOOD GROUP, SS; SS

Low match AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM-DEMENTIA COMPLEX


Amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam is a neurodegenerative disorder with unusually high incidence among the Chamorro people of Guam. Both ALS and parkinsonism-dementia are chronic, progressive, and uniformly fatal disorders in this population. Both diseases are known to occur in the same kindred, the same sibship, and even the same individual.

AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM-DEMENTIA COMPLEX Is also known as guam disease|als-pdc|parkinsonism-dementia-als complex|pdals|amyotrophic lateral sclerosis-parkinsonism-dementia of guam syndrome|amyotrophic lateral sclerosis-parkinsonism/dementia complex of guam|lytico-bodig disease

Related symptoms:

  • Muscle weakness
  • Dementia
  • Paralysis
  • Muscle cramps
  • Parkinsonism


SOURCES: OMIM ORPHANET MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM-DEMENTIA COMPLEX

Low match AMYOTROPHIC LATERAL SCLEROSIS 16, JUVENILE; ALS16


Related symptoms:

  • Muscle weakness
  • Spasticity
  • Hyperreflexia
  • Paralysis
  • Lower limb spasticity


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 16, JUVENILE; ALS16

Low match AMYOTROPHIC LATERAL SCLEROSIS 9; ALS9


Related symptoms:

  • Spasticity
  • Dementia
  • Distal muscle weakness
  • Distal amyotrophy
  • Parkinsonism


SOURCES: OMIM MESH MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 9; ALS9

Low match AMYOTROPHIC LATERAL SCLEROSIS 19; ALS19


Related symptoms:

  • Cognitive impairment
  • Respiratory insufficiency due to muscle weakness
  • Amyotrophic lateral sclerosis
  • Loss of ability to walk


SOURCES: OMIM MENDELIAN

More info about AMYOTROPHIC LATERAL SCLEROSIS 19; ALS19

Top 5 symptoms//phenotypes associated to Anemia and Amyotrophic lateral sclerosis

Symptoms // Phenotype % cases
Dementia Uncommon - Between 30% and 50% cases
Frontotemporal dementia Uncommon - Between 30% and 50% cases
Abnormal lower motor neuron morphology Uncommon - Between 30% and 50% cases
Muscle weakness Rare - less than 30% cases
Cognitive impairment Rare - less than 30% cases
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Other less frequent symptoms

Patients with Anemia and Amyotrophic lateral sclerosis. may also develop some of the following symptoms:

Rare Symptoms - Less than 30% cases


Spasticity Bulbar palsy Parkinsonism Pallor Paralysis Neuronal loss in central nervous system Skeletal muscle atrophy Abnormal upper motor neuron morphology Fasciculations Respiratory failure Hyporeflexia Gait disturbance Loss of ability to walk Respiratory insufficiency due to muscle weakness Distal amyotrophy Distal muscle weakness Lower limb spasticity Bulbar signs Hyperreflexia Mental deterioration Muscular dystrophy Elevated alkaline phosphatase Muscle cramps Rimmed vacuoles Muscle fiber inclusion bodies Neoplasm Upper motor neuron dysfunction Proximal amyotrophy



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