Abnormality of the skeletal system, and Asthma

Diseases related with Abnormality of the skeletal system and Asthma

In the following list you will find some of the most common rare diseases related to Abnormality of the skeletal system and Asthma that can help you solving undiagnosed cases.


Top matches:

Low match ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1


Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006).For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see {600807}.

ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1 Is also known as as1|asrt1

Related symptoms:

  • Dyspnea
  • Cough
  • Asthma
  • Inflammatory abnormality of the skin
  • Wheezing


SOURCES: OMIM MENDELIAN

More info about ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 1

Low match ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 2


Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002).For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see {600807}.

ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 2 Is also known as asrt2

Related symptoms:

  • Dyspnea
  • Cough
  • Asthma
  • Inflammatory abnormality of the skin
  • Wheezing


SOURCES: OMIM MENDELIAN

More info about ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 2

Low match ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 5


Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006).For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see {600807}.

ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 5 Is also known as asrt5

Related symptoms:

  • Dyspnea
  • Cough
  • Asthma
  • Inflammatory abnormality of the skin
  • Wheezing


SOURCES: OMIM MENDELIAN

More info about ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 5

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Other less relevant matches:

Low match ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 7; ASRT7


Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006).For a general phenotypic description and a discussion of genetic heterogeneity of asthma, see {600807}.

Related symptoms:

  • Dyspnea
  • Cough
  • Asthma
  • Inflammatory abnormality of the skin
  • Wheezing


SOURCES: OMIM MENDELIAN

More info about ASTHMA-RELATED TRAITS, SUSCEPTIBILITY TO, 7; ASRT7

Low match ASPERGILLOSIS, SUSCEPTIBILITY TO


Aspergillus species are ubiquitous in nature and cause a wide spectrum of diseases, including saprophytic colonization of existing cavities (aspergilloma), allergic asthma, hypersensitivity pneumonitis, allergic bronchopulmonary aspergillosis, and disseminated disease associated with high mortality rates in patients with hematologic malignancies and recipients of solid organs and stem cell transplantations. Immunocompetent and nonatopic individuals are relatively resistant to infection, and disease occurs in the setting of host damage. Association of persistent inflammation with intractable infection is common in nonneutropenic patients after hematopoietic stem cell transplantation, as well as in allergic fungal diseases. The pathophysiology underlying Aspergillus infection highlights the bipolar nature of the inflammatory process in infection, in which early inflammation prevents or limits infection, but an uncontrolled response may oppose disease eradication (summary by Cunha et al., 2010).For information on familial occurrence of allergic bronchopulmonary aspergillosis, see {103920}.

Related symptoms:

  • Asthma
  • Hypersensitivity pneumonitis


SOURCES: OMIM MENDELIAN

More info about ASPERGILLOSIS, SUSCEPTIBILITY TO

Low match PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE DEFICIENCY; PAFAD


Deficiency of plasma platelet-activating factor acetylhydrolase results in increased levels of PAF, a chemotactic lipid that activates inflammatory cells, bronchoconstriction, and airway hyperresponsiveness, and can moderate the release of inflammatory agonists. Asthmatic individuals with PAF acetylhydrolase deficiency may have exacerbated symptoms (summary by Stafforini et al., 1999).

Related symptoms:

  • Asthma
  • Increased level of platelet-activating factor
  • Platelet-activating factor acetylhydrolase deficiency


SOURCES: MESH OMIM MENDELIAN

More info about PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE DEFICIENCY; PAFAD

Low match ALLERGIC RHINITIS


Inflammation of the mucous membrane lining the nose due to allergy.

ALLERGIC RHINITIS Is also known as alrh

Related symptoms:

  • Asthma
  • Inflammatory abnormality of the skin
  • Rhinitis
  • Atopic dermatitis
  • Allergy


SOURCES: OMIM MENDELIAN

More info about ALLERGIC RHINITIS

Low match PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; COPD


Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality. COPD is defined by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. Airflow obstruction is typically determined by reductions in quantitative spirometric indices, including forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FVC) (Silverman et al., 2002; Celedon et al., 2004).

Related symptoms:

  • Asthma
  • Abnormal lung morphology
  • Emphysema
  • Bronchitis
  • Chronic lung disease


SOURCES: OMIM MENDELIAN

More info about PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; COPD

Low match CARBOXYPEPTIDASE N DEFICIENCY


An autosomal recessive condition caused by mutation(s) in the CPN1 gene, encoding carboxypeptidase N catalytic chain. It may be characterized by episodic angioedema, chronic urticaria, asthma and/or allergic hypersensitivity.

Related symptoms:

  • Fever
  • Asthma
  • Urticaria
  • Allergic rhinitis
  • Angioedema


SOURCES: MESH OMIM MENDELIAN

More info about CARBOXYPEPTIDASE N DEFICIENCY

Low match ASTHMA, SUSCEPTIBILITY TO


Bronchial asthma is the most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment.Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing, and dyspnea; bronchial hyperresponsiveness (BHR) as assessed by methacholine challenge test; serum IgE levels; atopy; and atopic dermatitis (Laitinen et al., 2001; Illig and Wjst, 2002; Pillai et al., 2006). See {147050} for information on the asthma-associated phenotype atopy.

ASTHMA, SUSCEPTIBILITY TO Is also known as asthma, bronchial|asthma-related traits, susceptibility to

Related symptoms:

  • Fever
  • Respiratory distress
  • Dyspnea
  • Cough
  • Asthma


SOURCES: OMIM MENDELIAN

More info about ASTHMA, SUSCEPTIBILITY TO

Top 5 symptoms//phenotypes associated to Abnormality of the skeletal system and Asthma

Symptoms // Phenotype % cases
Inflammatory abnormality of the skin Common - Between 50% and 80% cases
Atopic dermatitis Common - Between 50% and 80% cases
Dyspnea Uncommon - Between 30% and 50% cases
Wheezing Uncommon - Between 30% and 50% cases
Cough Uncommon - Between 30% and 50% cases
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Other less frequent symptoms

Patients with Abnormality of the skeletal system and Asthma. may also develop some of the following symptoms:

Uncommon Symptoms - Between 30% and 50% cases


Allergic rhinitis

Rare Symptoms - Less than 30% cases


Fever Chronic obstructive pulmonary disease Eczema Respiratory distress Angioedema Urticaria Chronic bronchitis Abnormal lung morphology Chronic lung disease Bronchitis Emphysema Allergy Rhinitis Platelet-activating factor acetylhydrolase deficiency Increased level of platelet-activating factor Hypersensitivity pneumonitis Chest tightness



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