RELA gene related symptoms and diseases

All the information presented here about the RELA gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,NCBIGENE,OMIM.

Top 5 symptoms associated to RELA gene



Symptoms // Phenotype % Cases
Milia Very Common - Between 80% and 100% cases
Neoplasm Very Common - Between 80% and 100% cases
Dysphagia Very Common - Between 80% and 100% cases
Obesity Very Common - Between 80% and 100% cases
Gastroesophageal reflux Very Common - Between 80% and 100% cases

Other less frequent symptoms

Patients with RELA gene alterations may also develop some of the following symptoms and phenotypes:

Commonly - More than 50% cases

Feeding difficulties in infancy

Not very common - Between 30% and 50% cases

Carcinoma

Commonly - More than 50% cases

Lymphadenopathy

Not very common - Between 30% and 50% cases

Nausea and vomiting

Commonly - More than 50% cases

Cough

Not very common - Between 30% and 50% cases

Chest pain

Commonly - More than 50% cases

Somatic mutation

Not very common - Between 30% and 50% cases

Esophagitis

And 3 more phenotypes.

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Rare diseases associated to RELA gene

Here you will find a list of rare diseases related to the RELA. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


BARRETT ESOPHAGUS

Alternate names

BARRETT ESOPHAGUS Is also known as barrett metaplasia;esophageal adenocarcinoma

Description

Barrett esophagus, or Barrett metaplasia, describes the phenotypic change of normal esophageal squamous epithelium to a columnar and intestinal-type epithelium. This metaplastic change is important because patients with Barrett esophagus have an increased risk of esophageal adenocarcinoma. The main cause of Barrett metaplasia is gastroesophageal reflux (GER ). The retrograde movement of acid and bile salts from the stomach into the esophagus in this disease causes prolonged injury to the esophageal epithelium and induces chronic esophagitis, which in turn is believed to trigger the pathologic changes (summary by Wong et al., 2005).

Most common symptoms of BARRETT ESOPHAGUS

  • Milia
  • Neoplasm
  • Dysphagia
  • Obesity
  • Gastroesophageal reflux


More info about BARRETT ESOPHAGUS

SOURCES: ICD10 MESH ORPHANET MONDO NCIT SCTID OMIM

Potential gene panels for RELA gene

RELA Panel

By Fulgent Genetics Fulgent Genetics in United States.

This panel specifically test the RELA gene.

More info about this panel

Tempus xO assay Panel

By Tempus Labs, Inc. in United States. Tempus xO assay that also includes the following genes: BRCA1 BRCA2 VHL APC EPCAM MSH2 PMS2 MSH6 MLH1 MUTYH

More info about this panel


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