Hepatitis B Virus, Susceptibility To

Table of contents:

Description
Related genes
Clinical Features
Incidence and onset information
Alternative Names
Researches and researchers
Gene Panels
Sources and references

Description

HBV is a DNA virus that enters the liver via the bloodstream, and replication occurs only in liver tissue. Transmission occurs by percutaneous or mucosal exposure to infected blood or other body fluids. Approximately one third of all cases of cirrhosis and half of all cases of hepatocellular carcinoma (HCC ) can be attributed to chronic HBV infection. Worldwide, 2 billion people have been infected with HBV, 360 million have chronic infection, and 600,000 die each year from HBV-related liver disease or HCC. However, there is marked geographic variability in HBV prevalence, with chronic infection affecting less than 2% of the populations of North America and western and northern Europe; between 2 and 7% of the populations of eastern and central Europe, the Amazon basin, the Middle East, and the Indian subcontinent; and more than 8% of the populations of Asia, sub-Saharan Africa, and the Pacific (Seeff and Hoofnagle, 2006; Shepard et al., 2006).

Genes related to Hepatitis B Virus, Susceptibility To

IFNGR1
IFNAR2
IL10RB

View recommended genes panels

Clinical Features

Top most frequent phenotypes and symptoms related to Hepatitis B Virus, Susceptibility To

Pain
Hepatomegaly
Fever
Vomiting
Splenomegaly
Abdominal pain
Jaundice
Carcinoma
Abnormality of the liver
Nausea

And another 10 symptoms. If you need more information about this disease we can help you.

Click here to know more about Mendelian.

Incidence and onset information

— Currently we don't have prevalence information about this disease (Not enough data available about incidence and published cases.)
— No data available about the known clinical features onset.

Alternative names

Hepatitis B Virus, Susceptibility To Is also known as hbv, susceptibility to.

Researches and researchers

Currently, we don't have any information about doctors, researches or researchers related to this disease. Please contact us if you would like to appear here.

Hepatitis B Virus, Susceptibility To Recommended genes panels

Panel Name, Specifity and genes Tested/covered
Interferon-gamma Receptor Deficiency: IFNGR1 (Full Gene Sequencing). By Molecular Diagnostic Laboratory University of Alberta (Canada). IFNGR1 Specificity 100 % Genes 34 %
Interferon-gamma Receptor Deficiency: IFNGR1 (Known Mutation). By Molecular Diagnostic Laboratory University of Alberta (Canada). IFNGR1 Specificity 100 % Genes 34 %
Interferon-gamma Receptor Deficiency: Two-gene Profile (IFNGR1, IFNGR2) (Full Gene Sequencing). By Molecular Diagnostic Laboratory University of Alberta (Canada). IFNGR1, IFNGR2 Specificity 50 % Genes 34 %
IFNGR1 Sequencing. By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States). IFNGR1 Specificity 100 % Genes 34 %
IFNGR1 Deletion/duplication analysis. By Cincinnati Children's Hospital Medical Center Laboratory of Genetics and Genomics Cincinnati Children's Hospital Medical Center (United States). IFNGR1 Specificity 100 % Genes 34 %
Immunodeficiency 27A, mycobacteriosis AR (sequence analysis of IFNGR1 gene). By CGC Genetics (Portugal). IFNGR1 Specificity 100 % Genes 34 %
Mycobacterial infection, atypical, familial disseminated. By Centogene AG - the Rare Disease Company (Germany). IFNGR1 Specificity 100 % Genes 34 %
Defects of phagocytosis Panel. By CeGaT GmbH (Germany). STAT1, TAZ, TCIRG1, TCN2, TERT, WAS, WIPF1, ACTB, VPS45, HPS3, HPS4, HAX1, HPS5, DTNBP1, CEBPE, HPS6, SBDS, SLC35C1, BLOC1S3, VPS13B , (...) View the complete list with 39 more genes Panel complete gene list STAT1, TAZ, TCIRG1, TCN2, TERT, WAS, WIPF1, ACTB, VPS45, HPS3, HPS4, HAX1, HPS5, DTNBP1, CEBPE, HPS6, SBDS, SLC35C1, BLOC1S3, VPS13B, FERMT3, CSF2RA, CSF3R, G6PC3, CTSC, CXCR4, CYBA, CYBB, USB1, JAGN1, MLPH, DNM2, LAMTOR2, SLC46A1, ELANE, FCGR3B, FPR1, ACKR1, ISG15, SLC37A4, GATA1, GATA2, GFI1, HFE, HPS1, IRF8, IFNGR1, IFNGR2, AP3B1, IL12B, IL12RB1, ITGB2, MPO, MYO5A, NCF1, NCF2, NCF4, RAB27A, RAC2 Specificity 2 % Genes 34 %

You can get up to 23 more panels with our dedicated tool

Learn more

Sources and references

You can check the following sources for additional information.

OMIM Genetic Syndrome Finder

If you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like SYNPOLYDACTYLY 1; SPD1 MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 2; MODY2 IMMUNODEFICIENCY 17; IMD17 EPILEPSY, FOCAL, WITH SPEECH DISORDER AND WITH OR WITHOUT MENTAL RETARDATION; FESD DEAFNESS-INFERTILITY SYNDROME; DIS SNEDDON SYNDROME CODAS SYNDROME