WISP3 gene related symptoms and diseases

All the information presented here about the WISP3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,OMIM,HGNC.

Top 5 symptoms associated to WISP3 gene



Symptoms // Phenotype % Cases
Autosomal recessive inheritance Very Common - Between 80% and 100% cases
Flattened epiphysis Very Common - Between 80% and 100% cases
Metaphyseal widening Very Common - Between 80% and 100% cases
Spondyloepiphyseal dysplasia Very Common - Between 80% and 100% cases
Rheumatoid arthritis Very Common - Between 80% and 100% cases

Other less frequent symptoms

Patients with WISP3 gene alterations may also develop some of the following symptoms and phenotypes:

Commonly - More than 50% cases

Arthropathy

Not very common - Between 30% and 50% cases

Joint swelling

Commonly - More than 50% cases

Abnormality of the knee

Not very common - Between 30% and 50% cases

Juvenile rheumatoid arthritis

Commonly - More than 50% cases

Synovitis

Not very common - Between 30% and 50% cases

Coxa vara

Commonly - More than 50% cases

Methylmalonic acidemia

Not very common - Between 30% and 50% cases

Osteochondroma

And 29 more phenotypes.

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Rare diseases associated to WISP3 gene

Here you will find a list of rare diseases related to the WISP3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC

Alternate names

ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC Is also known as progressive pseudorheumatoid arthropathy of childhood, spondyloepiphyseal dysplasia tarda with progressive arthropathy;sedt-pa, progressive pseudorheumatoid dysplasia;ppd;spondyloepiphyseal dysplasia tarda-progressive arthropathy syndrome

Description

Progressive pseudorheumatoid arthropathy (dysplasia) of childhood (PPAC; PPD) presents as spondyloepiphyseal dysplasia (SED) tarda with progressive arthropathy and is described as a specific autosomal recessive subtype of SED.

Most common symptoms of ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC

  • Autosomal recessive inheritance
  • Short stature
  • Scoliosis
  • Muscle weakness
  • Pain


More info about ARTHROPATHY, PROGRESSIVE PSEUDORHEUMATOID, OF CHILDHOOD; PPAC

SOURCES: OMIM MONDO SCTID MESH GARD DOID ORPHANET UMLS

Potential gene panels for WISP3 gene

WISP3 - Progressive pseudorheumatoid dysplasia (PPRD) Panel

By Centre of Molecular Diseases (CMM) CHUV in Switzerland.

This panel specifically test the WISP3 gene.

More info about this panel

WISP3. Complete sequencing Panel

By Instituto de Medicina Genomica Instituto de Medicina Genomica in Spain.

This panel specifically test the WISP3 gene.

More info about this panel

Arthropathy, progressive pseudorheumatoid of childhood (sequence analysis of WISP3 gene) Panel

By CGC Genetics in Portugal.

This panel specifically test the WISP3 gene.

More info about this panel

Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection Panel

By PreventionGenetics PreventionGenetics in United States. Skeletal Disorders and Joint Problems Sequencing Panel with CNV Detection that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 IFITM5 LRP5 COL2A1 COL1A1

More info about this panel

Spondylo-Epi-Metaphyseal dysplasias Deletion / Duplication panel Panel

By Connective Tissue Gene Tests in United States. Spondylo-Epi-Metaphyseal dysplasias Deletion / Duplication panel that also includes the following genes: COL2A1 FGFR3 COL10A1 IDUA RMRP RUNX2 SBDS SLC26A2 TRPV4 HSPG2

More info about this panel

Spondylo-Epi-Metaphyseal dysplasias Comprehensive panel Panel

By Connective Tissue Gene Tests in United States. Spondylo-Epi-Metaphyseal dysplasias Comprehensive panel that also includes the following genes: COL2A1 FGFR3 COL10A1 IDUA RMRP RUNX2 SBDS SLC26A2 TRPV4 HSPG2

More info about this panel

Spondylo-Epi-Metaphyseal dysplasias NGS panel Panel

By Connective Tissue Gene Tests in United States. Spondylo-Epi-Metaphyseal dysplasias NGS panel that also includes the following genes: COL2A1 FGFR3 COL10A1 IDUA RMRP RUNX2 SBDS SLC26A2 TRPV4 HSPG2

More info about this panel

Progressive pseudorheumatoid arthropathy of childhood Deletion / Duplication test Panel

By Connective Tissue Gene Tests in United States.

This panel specifically test the WISP3 gene.

More info about this panel

Progressive pseudorheumatoid arthropathy of childhood Sequencing test Panel

By Connective Tissue Gene Tests in United States.

This panel specifically test the WISP3 gene.

More info about this panel

Progressive pseudorheumatoid arthropathy of childhood Comprehensive test Panel

By Connective Tissue Gene Tests in United States.

This panel specifically test the WISP3 gene.

More info about this panel

Arthropathy, progressive pseudorheumatoid, of childhood Panel

By Centogene AG - the Rare Disease Company in Germany.

This panel specifically test the WISP3 gene.

More info about this panel

Single gene testing WISP3 Panel

By CeGaT GmbH in Germany.

This panel specifically test the WISP3 gene.

More info about this panel

Spondylometaphyseal dysplasia and Spondylo-epi-(meta)-physeal dysplasia Panel Panel

By CeGaT GmbH in Germany. Spondylometaphyseal dysplasia and Spondylo-epi-(meta)-physeal dysplasia Panel that also includes the following genes: COL2A1 SLC39A13 RMRP TRPV4 HSPG2 COL11A1 COL11A2 CANT1 DYM B3GALT6

More info about this panel

Progressive pseudorheumatoid arthropathy of childhood Panel

By Praxis fuer Humangenetik Wien in Austria.

This panel specifically test the WISP3 gene.

More info about this panel

Progressive pseudorheumatoid arthropathy of childhood Panel

By MedGene in Slovakia.

This panel specifically test the WISP3 gene.

More info about this panel

Arthropathy, progressive pseudorheumatoid, of childhood: WISP3 gene sequence analysis Panel

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases in Spain.

This panel specifically test the WISP3 gene.

More info about this panel

Skeletal dysplasias Panel

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases in Spain. Skeletal dysplasias that also includes the following genes: ALPL COL2A1 COL1A1 COL1A2 FGFR3 COL10A1 RMRP SBDS PEX7 SLC26A2

More info about this panel

Skeletal Dysplasia: Sequencing Panel Panel

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics in United States. Skeletal Dysplasia: Sequencing Panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 IFITM5 LRP5 COL2A1 COL1A1

More info about this panel

Pan-Ethnic Carrier Screen: Gene Sequencing Panel Panel

By EGL Genetic Diagnostics Eurofins Clinical Diagnostics in United States. Pan-Ethnic Carrier Screen: Gene Sequencing Panel that also includes the following genes: FMR1 HFE ACADM ACADS AGL ACADVL ACAT1 ALDOB ALPL BTD

More info about this panel

Skeletal Dysplasias NGS panel Panel

By Fulgent Genetics Fulgent Genetics in United States. Skeletal Dysplasias NGS panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 IFITM5 LRP5 COL2A1 COL1A1

More info about this panel

WISP3 Panel

By Fulgent Genetics Fulgent Genetics in United States.

This panel specifically test the WISP3 gene.

More info about this panel

Spondylometaphyseal / Spondyloepi-(meta)-physeal Dysplasia Panel Panel

By Blueprint Genetics in Finland. Spondylometaphyseal / Spondyloepi-(meta)-physeal Dysplasia Panel that also includes the following genes: COL2A1 SLC39A13 RMRP TRPV4 HSPG2 COL11A1 COL11A2 CANT1 DYM BGN

More info about this panel

Skeletal Dysplasias Core Panel Panel

By Blueprint Genetics in Finland. Skeletal Dysplasias Core Panel that also includes the following genes: ALPL ANKH FKBP10 LRP5 COL2A1 COL1A1 COL1A2 TGFB1 TNFRSF11A CLCN7

More info about this panel

Comprehensive Skeletal Dysplasias and Disorders Panel Panel

By Blueprint Genetics in Finland. Comprehensive Skeletal Dysplasias and Disorders Panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 LRP5 COL2A1 COL1A1 COL1A2

More info about this panel

Comprehensive Growth Disorders / Skeletal Dysplasias and Disorders Panel Panel

By Blueprint Genetics in Finland. Comprehensive Growth Disorders / Skeletal Dysplasias and Disorders Panel that also includes the following genes: RECQL4 ALPL ANKH TYROBP FKBP10 B4GALT7 BCS1L IFITM5 LRP5 COL2A1

More info about this panel

Progressive pseudorheumatoid arthropathy of childhood Panel

By Bioarray in Spain.

This panel specifically test the WISP3 gene.

More info about this panel

FoundationOne® Heme Panel

By Foundation Medicine, Inc. in United States. FoundationOne® Heme that also includes the following genes: BRCA1 BRCA2 VHL APC MSH2 MSH6 MLH1 MUTYH PTEN RUNX1

More info about this panel

NeoTYPE® Discovery Profile for Solid Tumors Panel

By NeoGenomics Laboratories NeoGenomics Laboratories, Inc. in United States. NeoTYPE® Discovery Profile for Solid Tumors that also includes the following genes: BRCA1 BRCA2 VHL APC MSH2 PMS2 MSH6 MLH1 MUTYH PTEN

More info about this panel

Caris MI TumorSeek 592-Gene NGS Panel Panel

By Caris Life Sciences in United States. Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BRCA1 BRCA2 VHL APC MSH2 PMS2 MSH6 MLH1 MUTYH PTEN

More info about this panel

Progressive Pseudorheumatoid Arthropathy of Childhood, Sequencing WISP3 Gene Panel

By Reference Laboratory Genetics in Spain.

This panel specifically test the WISP3 gene.

More info about this panel

Rheumatoid Type Osteoarthropathy and Related Disorders , Panel Massive Sequencing (NGS) 7 Genes Panel

By Reference Laboratory Genetics in Spain. Rheumatoid Type Osteoarthropathy and Related Disorders , Panel Massive Sequencing (NGS) 7 Genes that also includes the following genes: COL2A1 TRPV4 LPIN2 WISP3 IL1RN HPGD ACAN

More info about this panel

Skeletal Dysplasias , Panel Massive Sequencing (NGS) 36 Genes Panel

By Reference Laboratory Genetics in Spain. Skeletal Dysplasias , Panel Massive Sequencing (NGS) 36 Genes that also includes the following genes: ALPL COL2A1 COL1A1 COL1A2 FGFR3 COL10A1 RMRP SBDS PEX7 SLC26A2

More info about this panel

Pan-Ethnic Carrier Screen: Full Gene Sequencing and SMA Analysis Panel

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada. Pan-Ethnic Carrier Screen: Full Gene Sequencing and SMA Analysis that also includes the following genes: HFE ACADM ACADS AGL ACADVL ACAT1 ALDOB ALPL BTD ATP7B

More info about this panel

Progressive Pseudorheumatoid Dysplasia: gene sequencing Panel

By CEN4GEN Institute for Genomics and Molecular Diagnostics in Canada.

This panel specifically test the WISP3 gene.

More info about this panel


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