TGM3 gene related symptoms and diseases
All the information presented here about the TGM3 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: OMIM,ORPHANET,HGNC,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to TGM3 gene
|Symptoms // Phenotype||% Cases|
|Uncombable hair||Very Common - Between 80% and 100% cases|
|Pili canaliculi||Very Common - Between 80% and 100% cases|
|Depressivity||Uncommon - Between 30% and 50% cases|
|Alopecia areata||Uncommon - Between 30% and 50% cases|
|Hypotrichosis||Uncommon - Between 30% and 50% cases|
Other less frequent symptoms and clinical featuresPatients with TGM3 gene alterations may also develop some of the following symptoms and phenotypes:
Not very common - Between 30% and 50% cases
- Dry hair
- White hair
- Woolly hair
And 6 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to TGM3 gene
Here you will find a list of rare diseases related to the TGM3. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
UNCOMBABLE HAIR SYNDROME
UNCOMBABLE HAIR SYNDROME Is also known as pili trianguli et canaliculi, uncombable hair syndrome, uhs
Uncombable hair syndrome (UHS), or pili trianguli et canaliculi, is a rare scalp hair shaft dysplasia.
Most common symptoms of UNCOMBABLE HAIR SYNDROME
- Abnormality of the hair
- Coarse hair
More info about UNCOMBABLE HAIR SYNDROME
UNCOMBABLE HAIR SYNDROME 2; UHS2
Uncombable hair syndrome is characterized by silvery, blond, or straw-colored scalp hair that is dry, frizzy, and wiry, has a characteristic sheen, stands away from the scalp in multiple directions, and is impossible to comb. This hair shaft disorder occurs in children and improves with age. The hair growth rate can range from slow to normal (summary by U. Basmanav et al., 2016).For a general phenotypic description and a discussion of genetic heterogeneity of UHS, see UHS1 (OMIM ).
Most common symptoms of UNCOMBABLE HAIR SYNDROME 2; UHS2
- Juvenile cataract
More info about UNCOMBABLE HAIR SYNDROME 2; UHS2
Search interest in TGM3
Potential gene panels for TGM3 gene
By Fulgent Genetics Fulgent Genetics
This panel specifically test the TGM3 gene.More info about this panel
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