SUMO1 gene related symptoms and diseases

All the information presented here about the SUMO1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,ORPHANET,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to SUMO1 gene

Symptoms // Phenotype % Cases
Cleft lip Uncommon - Between 30% and 50% cases
Unilateral cleft lip Uncommon - Between 30% and 50% cases
Unilateral cleft palate Uncommon - Between 30% and 50% cases
Micrognathia Uncommon - Between 30% and 50% cases
Hypoplasia of the maxilla Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with SUMO1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Microdontia
  • Abnormality of the face
  • Oligodontia
  • Abnormality of dental morphology
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Rare diseases associated to SUMO1 gene

Here you will find a list of rare diseases related to the SUMO1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


OROFACIAL CLEFT 10; OFC10


Alternate names

OROFACIAL CLEFT 10; OFC10 Is also known as cleft lip with or without cleft palate, nonsyndromic, 10

Most common symptoms of OROFACIAL CLEFT 10; OFC10

  • Cleft lip
  • Unilateral cleft lip
  • Unilateral cleft palate


More info about OROFACIAL CLEFT 10; OFC10

SOURCES: OMIM MESH

OLIGODONTIA


Alternate names

OLIGODONTIA Is also known as selective tooth agenesis

Description

Oligodontia is a rare developmental dental anomaly in humans characterized by the absence of six or more teeth.

Most common symptoms of OLIGODONTIA

  • Micrognathia
  • Hypoplasia of the maxilla
  • Microdontia
  • Abnormality of the face
  • Oligodontia


More info about OLIGODONTIA

SOURCES: ORPHANET


Potential gene panels for SUMO1 gene

Cleft lip, cleft palate and related disorders NGS panel Panel

United States.

By Connective Tissue Gene Tests Cleft lip, cleft palate and related disorders NGS panel that also includes the following genes: BMP4 TBX22 SUMO1 TP63 TGDS SATB2 COL11A1 COL11A2 COL9A1 COL9A2

More info about this panel

Cleft lip, cleft palate and related disorders Deletion / Duplication panel Panel

United States.

By Connective Tissue Gene Tests Cleft lip, cleft palate and related disorders Deletion / Duplication panel that also includes the following genes: BMP4 TBX22 SUMO1 TP63 TGDS SATB2 COL11A1 COL11A2 COL9A1 COL9A2

More info about this panel

Cleft lip, cleft palate and related disorders Comprehensive panel Panel

United States.

By Connective Tissue Gene Tests Cleft lip, cleft palate and related disorders Comprehensive panel that also includes the following genes: BMP4 TBX22 SUMO1 TP63 TGDS SATB2 COL11A1 COL11A2 COL9A1 COL9A2

More info about this panel

SUMO1 Panel

Netherlands.

By Genome Diagnostics Laboratory University Medical Center Utrecht

This panel specifically test the SUMO1 gene.

More info about this panel

Orofacial cleft type 10 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the SUMO1 gene.

More info about this panel

Cleft lip/palate panel Panel

Germany.

By Centogene AG - the Rare Disease Company Cleft lip/palate panel that also includes the following genes: BMP4 SUMO1 TP63 IRF6 MSX1 NECTIN1

More info about this panel

qGenEx Craniofacial Anomalies Panel

Spain.

By Quantitative Genomic Medicine Laboratories, SL qGenEx Craniofacial Anomalies that also includes the following genes: RUNX2 SALL1 TSHZ1 BMP4 SEMA3E SF3B4 SH3BP2 SHH SIX1 SIX3

More info about this panel

SUMO1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the SUMO1 gene.

More info about this panel


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