SLITRK1 gene related symptoms and diseases

All the information presented here about the SLITRK1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to SLITRK1 gene

Symptoms // Phenotype % Cases
Depressivity Very Common - Between 80% and 100% cases
Obsessive-compulsive behavior Very Common - Between 80% and 100% cases
Hair-pulling Very Common - Between 80% and 100% cases
Tics Uncommon - Between 30% and 50% cases
Incoordination Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with SLITRK1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Self-injurious behavior
  • Impulsivity
  • Muscle fibrillation
  • Self-mutilation
  • Echolalia
  • Disinhibition
  • Dyslexia
  • Arnold-Chiari malformation

And 26 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to SLITRK1 gene

Here you will find a list of rare diseases related to the SLITRK1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


TRICHOTILLOMANIA; TTM


Description

Trichotillomania (TTM) is a neuropsychiatric disorder characterized by chronic, repetitive, or compulsive hair pulling resulting in noticeable hair loss. The activity causes distress to the individual and often interferes with functioning. Affected individuals may develop physical complications and often have overlapping psychologic disorders, such as Tourette syndrome (GTS ) or obsessive-compulsive disorder (OCD ) (review by Novak et al., 2009).

Most common symptoms of TRICHOTILLOMANIA; TTM

  • Depressivity
  • Alopecia
  • Obsessive-compulsive behavior
  • Alopecia of scalp
  • Hair-pulling


More info about TRICHOTILLOMANIA; TTM

SOURCES: MESH OMIM

GILLES DE LA TOURETTE SYNDROME; GTS


Alternate names

GILLES DE LA TOURETTE SYNDROME; GTS Is also known as ts, tourette syndrome, tourette disorder

Description

Tourette syndrome is a neurobehavioral disorder manifest particularly by motor and vocal tics and associated with behavioral abnormalities. Tics are sudden, brief, intermittent, involuntary or semi-voluntary movements (motor tics) or sounds (phonic or vocal tics). They typically consist of simple, coordinated, repetitive movements, gestures, or utterances that mimic fragments of normal behavior. Motor tics may range from simple blinking, nose twitching, and head jerking to more complex throwing, hitting, or making rude gestures. Phonic tics include sniffling, throat clearing, blowing, coughing, echolalia, or coprolalia. Males are affected about 3 times more often than females, and onset usually occurs between 3 and 8 years of age. By age 18 years, more than half of affected individuals are free of tics, but they may persist into adulthood (review by Jankovic, 2001).

Most common symptoms of GILLES DE LA TOURETTE SYNDROME; GTS

  • Behavioral abnormality
  • Depressivity
  • Pectus excavatum
  • Myoclonus
  • Hyperactivity


More info about GILLES DE LA TOURETTE SYNDROME; GTS

SOURCES: MESH OMIM


Potential gene panels for SLITRK1 gene

SLITRK1. Complete sequencing Panel

Spain.

By Instituto de Medicina Genomica Instituto de Medicina Genomica

This panel specifically test the SLITRK1 gene.

More info about this panel

Tourette syndrome (sequence analysis of SLITRK1 gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the SLITRK1 gene.

More info about this panel

Tourette syndrome Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the SLITRK1 gene.

More info about this panel

Gilles de la Tourette Syndrom Panel

Austria.

By Praxis fuer Humangenetik Wien

This panel specifically test the SLITRK1 gene.

More info about this panel

Trichotillomania Panel

Austria.

By Praxis fuer Humangenetik Wien

This panel specifically test the SLITRK1 gene.

More info about this panel

Gilles de la Tourette Syndrom Panel

Slovakia.

By MedGene

This panel specifically test the SLITRK1 gene.

More info about this panel

Trichotillomania Panel

Slovakia.

By MedGene

This panel specifically test the SLITRK1 gene.

More info about this panel

SLITRK1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the SLITRK1 gene.

More info about this panel

Tourette syndrome Panel

Spain.

By Bioarray

This panel specifically test the SLITRK1 gene.

More info about this panel

TOURETTE SYNDROME Panel

Spain.

By Laboratorio de Genetica Clinica SL TOURETTE SYNDROME that also includes the following genes: SLITRK1 HDC

More info about this panel

Tourette Syndrome , Sequencing SLITRK1 Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the SLITRK1 gene.

More info about this panel


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