SLC6A2 gene related symptoms and diseases

All the information presented here about the SLC6A2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM,ORPHANET, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to SLC6A2 gene

Symptoms // Phenotype % Cases
Fatigue Very Common - Between 80% and 100% cases
Anxiety Very Common - Between 80% and 100% cases
Irritability Very Common - Between 80% and 100% cases
Vertigo Very Common - Between 80% and 100% cases
Nausea Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with SLC6A2 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Hypotension
  • Mitral valve prolapse
  • Orthostatic hypotension
  • Chronic fatigue
  • Asthenia
  • Orthostatic tachycardia
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Rare diseases associated to SLC6A2 gene

Here you will find a list of rare diseases related to the SLC6A2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME DUE TO NET DEFICIENCY


Alternate names

POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME DUE TO NET DEFICIENCY Is also known as pots due to net deficiency, orthostatic intolerance due to net deficiency, neurocirculatory asthenia, mitral valve prolapse syndrome, familial orthostatic tachycardia due to norepinephrine transporter deficiency, soldiers heart, irritable heart

Description

A condition characterized by development of symptoms while standing. It is an autonomic nervous system disorder and the symptoms are relieved once the person sits back down. Symptoms include heart palpitations, sweating, anxiety, lightheadedness, hyperpnea, anxiety, and blurred vision.

Most common symptoms of POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME DUE TO NET DEFICIENCY

  • Fatigue
  • Anxiety
  • Irritability
  • Vertigo
  • Nausea


More info about POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME DUE TO NET DEFICIENCY

SOURCES: OMIM ORPHANET


Potential gene panels for SLC6A2 gene

Orthostatic intolerance (sequence analysis of SLC6A2 gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the SLC6A2 gene.

More info about this panel

Hyperekplexia panel Panel

Germany.

By Centogene AG - the Rare Disease Company Hyperekplexia panel that also includes the following genes: SLC6A2 ARHGEF9 GPHN GLRA1 GLRB

More info about this panel

Orthostatic intolerance Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the SLC6A2 gene.

More info about this panel

SLC6A2 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the SLC6A2 gene.

More info about this panel


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