SLC11A1 gene related symptoms and diseases
All the information presented here about the SLC11A1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,HGNC,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to SLC11A1 gene
Symptoms // Phenotype | % Cases |
---|---|
Fever | Common - Between 50% and 80% cases |
Fatigue | Common - Between 50% and 80% cases |
Weight loss | Common - Between 50% and 80% cases |
Cough | Common - Between 50% and 80% cases |
Pain | Uncommon - Between 30% and 50% cases |
Other less frequent symptoms and clinical features
Patients with SLC11A1 gene alterations may also develop some of the following symptoms and phenotypes:Not very common - Between 30% and 50% cases
- Immunodeficiency
- Chest pain
- Hemoptysis
- Night sweats
- Edema
- Abnormal lung morphology
Rare diseases associated to SLC11A1 gene
Here you will find a list of rare diseases related to the SLC11A1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
Description
Mycobacterium tuberculosis latently infects approximately one-third of humanity and is comparable only to human immunodeficiency virus (HIV; see {609423}) as a leading infectious cause of mortality worldwide. Obstacles for controlling TB infection include lengthy treatment regimens of 6 to 9 months, drug resistance, lack of a highly efficacious vaccine, and incomplete understanding of the factors that control infectivity and disease progression. Although only 10% of individuals infected with M. tuberculosis develop active disease, the immune responses associated with TB susceptibility or resistance are not known. In addition, it is not known why some individuals have disseminated TB that spreads to the meninges and central nervous system, while most people have localized disease in the lungs. A number of studies suggest that host genetic factors influence susceptibility and resistance to TB (review by Berrington and Hawn, 2007).
Most common symptoms of MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
- Pain
- Fever
- Fatigue
- Immunodeficiency
- Weight loss
More info about MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO
BURULI ULCER, SUSCEPTIBILITY TO
Alternate names
BURULI ULCER, SUSCEPTIBILITY TO Is also known as mycobacterium ulcerans, susceptibility to
Description
Buruli ulcer is an infectious disease prevalent in many tropical and subtropical regions caused by infection with Mycobacterium ulcerans. It is the third most frequent mycobacterial disease in humans worldwide, after tuberculosis (OMIM ) and leprosy (OMIM ). Lesions are most common on exposed parts of the body, especially the limbs. Buruli ulcer derives its name from a county in Uganda, East Africa, north of Kampala, where the disease was found in the late 1950s in hundreds of people living near marshes and riverine areas near the Nile River (Clancey et al., 1961; Barker, 1971). The disease was first described in the medical literature in 1948 in a report on patients in Australia (MacCallum et al., 1948). Patients have also been reported from tropical areas in Latin America and Asia (Stienstra et al., 2006; van der Werf et al., 2005).
Most common symptoms of BURULI ULCER, SUSCEPTIBILITY TO
- Edema
More info about BURULI ULCER, SUSCEPTIBILITY TO
SOURCES: OMIM
TUBERCULOSIS
Description
Tuberculosis (TB) is a contagious-infectious disease caused mainly by Mycobacterium tuberculosis that in most individuals is usually asymptomatic but that in at risk individuals (e.g. with diabetes or with HIV infection) can cause weakness, fever, weight loss, night sweat, and respiratory anomalies such as chronic cough, chest pain, hemoptysis or respiratory insufficiency.
Most common symptoms of TUBERCULOSIS
- Fever
- Fatigue
- Weight loss
- Cough
- Abnormal lung morphology
More info about TUBERCULOSIS
SOURCES: ORPHANET
Search interest in SLC11A1
Potential gene panels for SLC11A1 gene
SLC11A1 Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the SLC11A1 gene.
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like KDM2B NUBPL USF1 PRKG1 RHBDF2 GRID2 WDR35