RPS15 gene related symptoms and diseases

All the information presented here about the RPS15 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,NCBIGENE,HGNC,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to RPS15 gene

Symptoms // Phenotype % Cases
Neoplasm Very Common - Between 80% and 100% cases
Rheumatoid arthritis Very Common - Between 80% and 100% cases
Lung adenocarcinoma Very Common - Between 80% and 100% cases
Lymphocytosis Very Common - Between 80% and 100% cases
Cellular immunodeficiency Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with RPS15 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Chronic lymphatic leukemia
  • Lymphoproliferative disorder
  • B-cell lymphoma
  • Acute leukemia
  • Hodgkin lymphoma
  • Hyperthyroidism
  • Systemic lupus erythematosus
  • Anemia

And 10 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to RPS15 gene

Here you will find a list of rare diseases related to the RPS15. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA


Alternate names

B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA Is also known as b-cll, small lymphocytic lymphoma, b-cell chronic lymphoid leukemia, leukemia, chronic lymphatic

Description

B-cell chronic lymphocytic leukemia (B-CLL) is a type of B-cell non-Hodgkin lymphoma (see this term), and the most common form of leukemia in Western countries, affecting elderly adults (mean age of 67 and 72 years) with a slight male predominance (1.7:1), and characterized by a highly variable clinical presentation that can include asymptomatic disease or non-specific B-symptoms such as unintentional weight loss, severe fatigue, fever (without evidence of infection), and night sweats as well as cervical lymphadenopathy, splenomegaly and frequent infections. Some patients can also develop autoimmune complications such as autoimmune hemolytic anemia or immune thrombocytopenia (see these terms). The clinical course is extremely heterogeneous with survival ranging from a few months to several decades.

Most common symptoms of B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA

  • Neoplasm
  • Anemia
  • Splenomegaly
  • Recurrent infections
  • Thrombocytopenia


More info about B-CELL CHRONIC LYMPHOCYTIC LEUKEMIA

SOURCES: OMIM ORPHANET


Potential gene panels for RPS15 gene

Bone Marrow Failure Panel

United States.

By Knight Diagnostic Laboratories - Molecular Diagnostic Center Oregon Health & Science University Bone Marrow Failure that also includes the following genes: RPL11 RPL35A RPL5 RPS10 RPS15 RPS19 RPS24 RPS26 RPS27A RPS7

More info about this panel

NGS Panel for Diamond-Blackfan Anemia Panel

Spain.

By BLOODGENETICS BLOODGENETICS NGS Panel for Diamond-Blackfan Anemia that also includes the following genes: RPL11 RPL15 RPL19 RPL26 RPL27 RPL31 RPL35A RPL5 RPL9 RPS10

More info about this panel

RPS15 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the RPS15 gene.

More info about this panel

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel


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