RASA2 gene related symptoms and diseases

All the information presented here about the RASA2 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: ORPHANET,OMIM,NCBIGENE,HGNC, Mendelian Rare Disease Search Engine.

Table of contents:

Main symptoms and clinical features
Other symptoms and clinical features
Related Diseases
Current trends
Suitable testing panels

Top 5 symptoms and clinical features associated to RASA2 gene

Symptoms // Phenotype	% Cases
Intellectual disability	Very Common - Between 80% and 100% cases
Acute leukemia	Very Common - Between 80% and 100% cases
Thoracic scoliosis	Very Common - Between 80% and 100% cases
Aortic root aneurysm	Very Common - Between 80% and 100% cases
Acute lymphoblastic leukemia	Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with RASA2 gene alterations may also develop some of the following symptoms and phenotypes:

Commonly - More than 50% cases
Pulmonary artery stenosis
Abnormality of the mouth
Thickened nuchal skin fold
Premature skin wrinkling
Male infertility
High anterior hairline
Abnormality of the testis
Abnormality of the helix

And 145 more phenotypes, you can get all of them using our tools for rare diseases.

Rare diseases associated to RASA2 gene

Here you will find a list of rare diseases related to the RASA2. You can also use our tool to get a more accurate diagnosis based on your current symptoms.

NOONAN SYNDROME

Description

Noonan Syndrome (NS) is characterised by short stature, typical facial dysmorphism and congenital heart defects.

Most common symptoms of NOONAN SYNDROME

Intellectual disability
Short stature
Hearing impairment
Scoliosis
Growth delay

More info about NOONAN SYNDROME

SOURCES: ORPHANET

Search interest in RASA2

Potential gene panels for RASA2 gene

NGS RASopathy Panel Panel

United States.

By Greenwood Genetic Center Diagnostic Laboratories Greenwood Genetic Center NGS RASopathy Panel that also includes the following genes: RIT1 RRAS BRAF SOS1 SOS2 CBL SHOC2 KAT6B SPRED1 A2ML1

RASA2 gene related symptoms and diseases

Top 5 symptoms and clinical features associated to RASA2 gene

Other less frequent symptoms and clinical features

Commonly - More than 50% cases

Rare diseases associated to RASA2 gene

NOONAN SYNDROME

Description

Most common symptoms of NOONAN SYNDROME

Search interest in RASA2

Potential gene panels for RASA2 gene

NGS RASopathy Panel Panel

Rasopathy NextGen Panel Panel

Non-NF1 RASopathy Next Generation Sequencing and Deletion/Duplication Panel

Noonan Spectrum Disorders/Rasopathies Sequencing Panel with CNV Detection Panel

Noonan Syndrome via RASA2Gene Sequencing with CNV Detection Panel

Noonan spectrum disorder Comprehensive panel Panel

Noonan spectrum disorder Deletion / Duplication panel Panel

Noonan spectrum disorder NGS panel Panel

Hypertrophic cardiomyopathy - different panels Panel

Mental retardation - different panels Panel

Noonan syndrome - different panels Panel

Heart Diseases - panels Panel

Mental Retardation and Dysmorphology - panels Panel

Syndromal Diseases - panels Panel

RASopathies Panel

Noonan Syndrome Panel

RASopathies Panel Panel

RASopathies Panel Panel

RASopathies Panel Panel

Cardiovascular Diseases_General Panel Panel

Arrhythmia General Panel Panel

Cardiomyopathies General Panel Panel

RASopathies Panel Panel

RASOPATHY-RELATED SYNDROME Panel

NOONAN SYNDROME Panel

RASA2 Panel

Cardiomyopathy Panel Panel

Comprehensive Short Stature Syndrome Panel Panel

Hereditary Pediatric Cancer Panel Panel

Comprehensive Hereditary Cancer Panel Panel

Comprehensive Cardiology Panel Panel

Noonan Syndrome Panel Panel

Comprehensive Growth Disorders / Skeletal Dysplasias and Disorders Panel Panel

NOONAN SYNDROME Panel

NOONAN & NOONAN-LIKE SYNDROMES : NGS PANEL Panel