PLA2G2A gene related symptoms and diseases
All the information presented here about the PLA2G2A gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,NCBIGENE,OMIM, Mendelian Rare Disease Search Engine.
Top 5 symptoms and clinical features associated to PLA2G2A gene
Symptoms // Phenotype | % Cases |
---|---|
Neoplasm | Very Common - Between 80% and 100% cases |
Carcinoma | Very Common - Between 80% and 100% cases |
Oligodontia | Very Common - Between 80% and 100% cases |
Colon cancer | Very Common - Between 80% and 100% cases |
Colitis | Very Common - Between 80% and 100% cases |
Other less frequent symptoms and clinical features
Patients with PLA2G2A gene alterations may also develop some of the following symptoms and phenotypes:Commonly - More than 50% cases
- Renal cell carcinoma
- Ulcerative colitis
- Retinoblastoma
- Leiomyosarcoma
- Endometrial carcinoma
- Colorectal polyposis
- Transitional cell carcinoma of the bladder
- Hereditary nonpolyposis colorectal carcinoma
And 2 more phenotypes, you can get all of them using our tools for rare diseases.
Rare diseases associated to PLA2G2A gene
Here you will find a list of rare diseases related to the PLA2G2A. You can also use our tool to get a more accurate diagnosis based on your current symptoms.
COLORECTAL CANCER; CRC
Alternate names
COLORECTAL CANCER; CRC Is also known as colon cancer
Description
Colorectal cancer is a heterogeneous disease that is common in both men and women. In addition to lifestyle and environmental risk factors, gene defects can contribute to an inherited predisposition to CRC. CRC is caused by changes in different molecular pathogenic pathways, such as chromosomal instability, CpG island methylator phenotype, and microsatellite instability. Chromosome instability is the most common alteration and is present in almost 85% of all cases (review by Schweiger et al., 2013).
Most common symptoms of COLORECTAL CANCER; CRC
- Neoplasm
- Carcinoma
- Oligodontia
- Colon cancer
- Colitis
More info about COLORECTAL CANCER; CRC
SOURCES: OMIM
Search interest in PLA2G2A
Potential gene panels for PLA2G2A gene
MitoMet®Plus aCGH Analysis Panel
By Baylor Miraca Genetics Laboratories MitoMet®Plus aCGH Analysis that also includes the following genes: RGS9 RHO GRK1 RLBP1 RNASEL BCS1L RP1 RP2 RP9 RPE65
More info about this panelPLA2G2A Panel
By Fulgent Genetics Fulgent Genetics
This panel specifically test the PLA2G2A gene.
More info about this panelTempus xO assay Panel
By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2
More info about this panelPrimBio Colorectal Cancer Panel Panel
By PrimBio Research Institute PrimBio Research Institute PrimBio Colorectal Cancer Panel that also includes the following genes: BLM BMPR1A SCG5 BRAF BRCA1 STK11 BUB1B EPCAM TCF7L2 TGFBR2
More info about this panelIf you liked this article maybe you will also find interesting the following in-depth articles about other rare diseases, like EPG5 BCL10 CLCN1 USF1 RLBP1 SLC6A18 MYO1E