OPCML gene related symptoms and diseases

All the information presented here about the OPCML gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,HGNC,OMIM, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to OPCML gene

Symptoms // Phenotype % Cases
Neoplasm Very Common - Between 80% and 100% cases
Abdominal distention Very Common - Between 80% and 100% cases
Non-Hodgkin lymphoma Very Common - Between 80% and 100% cases
Dysgerminoma Very Common - Between 80% and 100% cases
Ovarian carcinoma Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with OPCML gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Hodgkin lymphoma
  • Ovarian neoplasm
  • Back pain
  • Breast carcinoma
  • Melanoma
  • Increased body weight
  • Lymphoma
  • Ascites

And 13 more phenotypes, you can get all of them using our tools for rare diseases.


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Rare diseases associated to OPCML gene

Here you will find a list of rare diseases related to the OPCML. You can also use our tool to get a more accurate diagnosis based on your current symptoms.



Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases (Chi et al., 2001). These typical features relate to the biology of the disease, which is a principal determinant of outcome (Auersperg et al., 2001). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium (Stany et al., 2008; Soslow, 2008).

Most common symptoms of OVARIAN CANCER

  • Neoplasm
  • Pain
  • Fatigue
  • Respiratory distress
  • Vomiting

More info about OVARIAN CANCER


Potential gene panels for OPCML gene


United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the OPCML gene.

More info about this panel

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