MNX1 gene related symptoms and diseases

All the information presented here about the MNX1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: HGNC,ORPHANET,OMIM,NCBIGENE, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to MNX1 gene

Symptoms // Phenotype % Cases
Hypospadias Very Common - Between 80% and 100% cases
Vesicoureteral reflux Very Common - Between 80% and 100% cases
Hypoplasia of penis Very Common - Between 80% and 100% cases
Abnormal intestine morphology Very Common - Between 80% and 100% cases
Bifid scrotum Very Common - Between 80% and 100% cases

Other less frequent symptoms and clinical features

Patients with MNX1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Commonly - More than 50% cases

  • Male pseudohermaphroditism
  • Arteriovenous malformation
  • Lower limb asymmetry
  • Sacrococcygeal teratoma
  • Aplasia/Hypoplasia of the sacrum
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Rare diseases associated to MNX1 gene

Here you will find a list of rare diseases related to the MNX1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


CURRARINO SYNDROME


Alternate names

CURRARINO SYNDROME Is also known as currarino triad

Description

Currarino syndrome (CS) is a rare congenital disease characterized by the triad of anorectal malformations (ARMs) (usually anal stenosis), presacral mass (commonly anterior sacral meningocele (ASM) or teratoma) and sacral anomalies (i.e. total or partial agenesis of the sacrum and coccyx or deformity of the sacral vertebrae).

Most common symptoms of CURRARINO SYNDROME

  • Hypospadias
  • Vesicoureteral reflux
  • Hypoplasia of penis
  • Abnormal intestine morphology
  • Bifid scrotum


More info about CURRARINO SYNDROME

SOURCES: ORPHANET


Potential gene panels for MNX1 gene

Neonatal Diabetes Mellitus and Maturity-Onset Diabetes of the Young Deletion/Duplication Panel Panel

United States.

By Genetic Services Laboratory University of Chicago Neonatal Diabetes Mellitus and Maturity-Onset Diabetes of the Young Deletion/Duplication Panel that also includes the following genes: BLK SLC2A2 STAT3 KLF11 WFS1 ZBTB20 NEUROG3 LRBA CDKN1C CEL

More info about this panel

Neonatal Diabetes Mellitus and Maturity-Onset Diabetes of the Young Panel Panel

United States.

By Genetic Services Laboratory University of Chicago Neonatal Diabetes Mellitus and Maturity-Onset Diabetes of the Young Panel that also includes the following genes: BLK SLC2A2 STAT3 KLF11 WFS1 ZBTB20 NEUROG3 LRBA CDKN1C CEL

More info about this panel

Comprehensive Neonatal Diabetes Mutation Analysis Panel

United States.

By Genetic Services Laboratory University of Chicago Comprehensive Neonatal Diabetes Mutation Analysis that also includes the following genes: ZFP57 EIF2AK3 GATA4 GATA6 GCK MNX1 HYMAI ABCC8 INS FOXP3

More info about this panel

Neonatal Diabetes Mellitus Sequencing Panel Panel

United States.

By Genetic Services Laboratory University of Chicago Neonatal Diabetes Mellitus Sequencing Panel that also includes the following genes: ZFP57 EIF2AK3 GATA4 GATA6 GCK MNX1 ABCC8 INS FOXP3 PDX1

More info about this panel

MNX1 sequencing Panel

United States.

By Genetic Services Laboratory University of Chicago

This panel specifically test the MNX1 gene.

More info about this panel

MNX1 deletion/duplication analysis Panel

United States.

By Genetic Services Laboratory University of Chicago

This panel specifically test the MNX1 gene.

More info about this panel

HLXB9. Complete sequencing Panel

Spain.

By Instituto de Medicina Genomica Instituto de Medicina Genomica

This panel specifically test the MNX1 gene.

More info about this panel

Currarino syndrome (sequence analysis of MNX1 gene) Panel

Portugal.

By CGC Genetics

This panel specifically test the MNX1 gene.

More info about this panel

CURRARINO Syndrome Panel

Belgium.

By Centre de Genetique Humaine Institut de Pathologie et de Genetique

This panel specifically test the MNX1 gene.

More info about this panel

Currarino Syndrome via MNX1 Gene Sequencing with CNV Detection Panel

United States.

By PreventionGenetics PreventionGenetics

This panel specifically test the MNX1 gene.

More info about this panel

Currarino syndrome Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the MNX1 gene.

More info about this panel

Currarino syndrome Panel

Austria.

By Praxis fuer Humangenetik Wien

This panel specifically test the MNX1 gene.

More info about this panel

qChip Panel

Spain.

By Quantitative Genomic Medicine Laboratories, SL qChip that also includes the following genes: RS1 RUNX2 SALL1 SCN1A BMPR1A SH2D1A SEM1 SHH SHOX SIM1

More info about this panel

Currarino syndrome Panel

Slovakia.

By MedGene

This panel specifically test the MNX1 gene.

More info about this panel

Currarino syndrome: MNX1(HLXB9) gene sequence analysis Panel

Spain.

By GENETAQ Molecular Genetics Centre and Diagnosis of Rare Diseases

This panel specifically test the MNX1 gene.

More info about this panel

MNX1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MNX1 gene.

More info about this panel

Currarino triad Panel

Spain.

By Bioarray

This panel specifically test the MNX1 gene.

More info about this panel

Rapid microarray (CGH and SNP) Panel

United States.

By Allele Diagnostics Allele Diagnostics Rapid microarray (CGH and SNP) that also includes the following genes: RPS19 RUNX2 SALL1 SCN1A SCN2A SDHB SDHD BMPR1A SGCE SH2D1A

More info about this panel

High-Resolution Rapid Microarray (CGH and SNP) Panel

United States.

By Allele Diagnostics Allele Diagnostics High-Resolution Rapid Microarray (CGH and SNP) that also includes the following genes: RPS19 RUNX2 SALL1 SCN1A SCN2A SDHB SDHD BMPR1A SGCE SH2D1A

More info about this panel

Caris MI TumorSeek 592-Gene NGS Panel Panel

United States.

By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1

More info about this panel

Currarino syndrome Panel

Canada.

By LifeLabs Genetics

This panel specifically test the MNX1 gene.

More info about this panel

Currarino Syndrome, Sequencing MNX1 (HLXB9) Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the MNX1 gene.

More info about this panel

Currarino Syndrome, Deletions-Duplications (MLPA) MNX1 (HLXB9) Gene Panel

Spain.

By Reference Laboratory Genetics

This panel specifically test the MNX1 gene.

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


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