MALT1 gene related symptoms and diseases

All the information presented here about the MALT1 gene and its related diseases, symptoms, and test panels has been aggregated from the following public sources: NCBIGENE,ORPHANET,OMIM,HGNC, Mendelian Rare Disease Search Engine.

Top 5 symptoms and clinical features associated to MALT1 gene

Symptoms // Phenotype % Cases
Anemia Uncommon - Between 30% and 50% cases
Recurrent bacterial infections Uncommon - Between 30% and 50% cases
Pneumonia Uncommon - Between 30% and 50% cases
Osteoporosis Uncommon - Between 30% and 50% cases
Inflammatory abnormality of the skin Uncommon - Between 30% and 50% cases

Other less frequent symptoms and clinical features

Patients with MALT1 gene alterations may also develop some of the following symptoms and phenotypes:
  • Not very common - Between 30% and 50% cases

  • Bronchiectasis
  • Meningitis
  • Recurrent pneumonia
  • Clubbing
  • Immunodeficiency
  • Gingivitis
  • Esophagitis
  • Abnormality of the gastrointestinal tract

And 24 more phenotypes, you can get all of them using our tools for rare diseases.

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Rare diseases associated to MALT1 gene

Here you will find a list of rare diseases related to the MALT1. You can also use our tool to get a more accurate diagnosis based on your current symptoms.


MALT LYMPHOMA


Alternate names

MALT LYMPHOMA Is also known as maltoma, mucosa-associated lymphatic tissue lymphoma, extranodal marginal zone b-cell lymphoma, mucosa-associated lymphoid tissue lymphoma

Description

MALT (mucosa-associated lymphoid tissue) lymphoma is a rare form of malignant non-Hodgkin lymphoma (see this term) that affects B cells and grows at the expense of lymphoid tissue associated with mucous membranes, but also occurs, more rarely, in lymph nodes.

Most common symptoms of MALT LYMPHOMA

  • Anemia
  • Visual impairment
  • Fever
  • Fatigue
  • Constipation


More info about MALT LYMPHOMA

SOURCES: ORPHANET

COMBINED IMMUNODEFICIENCY DUE TO MALT1 DEFICIENCY


Description

Combined immunodeficiency due to MALT1 deficiency is a rare, genetic form of primary immunodeficiency characterized by growth retardation, early recurrent pulmonary infections leading to bronchiectasis, inflammatory gastrointestinal disease, and other symptoms, such as rash, dermatitis, skin infections.

Most common symptoms of COMBINED IMMUNODEFICIENCY DUE TO MALT1 DEFICIENCY

  • Growth delay
  • Abnormal facial shape
  • Immunodeficiency
  • Delayed skeletal maturation
  • Pneumonia


More info about COMBINED IMMUNODEFICIENCY DUE TO MALT1 DEFICIENCY

SOURCES: OMIM ORPHANET


Potential gene panels for MALT1 gene

Detection by FISH of MALT1 (18q21) rearrangements Panel

Portugal.

By CGC Genetics

This panel specifically test the MALT1 gene.

More info about this panel

Detection by FISH of t(11;18) API2/MALT1 Panel

Portugal.

By CGC Genetics Detection by FISH of t(11;18) API2/MALT1 that also includes the following genes: BIRC3 MALT1

More info about this panel

Detection by FISH of t(14;18) IGH/MALT1 Panel

Portugal.

By CGC Genetics Detection by FISH of t(14;18) IGH/MALT1 that also includes the following genes: IGH MALT1

More info about this panel

CentoICU platinum plus Panel

Germany.

By Centogene AG - the Rare Disease Company CentoICU platinum plus that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC

More info about this panel

New Born testing (CentoICU) Panel

Germany.

By Centogene AG - the Rare Disease Company New Born testing (CentoICU) that also includes the following genes: RMRP BCS1L BDNF RPS19 RPS6KA3 SALL1 SCN1A SCN2A SFTPB SFTPC

More info about this panel

Immunodeficiency type 12 Panel

Germany.

By Centogene AG - the Rare Disease Company

This panel specifically test the MALT1 gene.

More info about this panel

FISH, Lymphoma Panel Panel

United States.

By Cytogenetics and Molecular Pathology Laboratory UP Health System Marquette FISH, Lymphoma Panel that also includes the following genes: BCL6 CCND1 IGH MALT1 MYC

More info about this panel

Combined immunodeficiencies Panel Panel

Germany.

By CeGaT GmbH Combined immunodeficiencies Panel that also includes the following genes: RMRP SEMA3E STAT5B STIM1 STK4 TAPBP TBX1 THBD TNFRSF4 CD40

More info about this panel

Invitae Comprehensive Severe Combined Immunodeficiency (SCID) and Combined Immunodeficiency (CID) Panel Panel

United States.

By Invitae Invitae Comprehensive Severe Combined Immunodeficiency (SCID) and Combined Immunodeficiency (CID) Panel that also includes the following genes: STK4 TAPBP TNFRSF4 CD27 CD40LG ZAP70 CARD11 CD3D CD3E CD3G

More info about this panel

Invitae Primary Immunodeficiency Panel Panel

United States.

By Invitae Invitae Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC SEMA3E SH2D1A SH3BP2 SLC7A7 SMARCAL1 BTK STAT1 STAT2

More info about this panel

Invitae Combined Immunodeficiency (CID) Panel Panel

United States.

By Invitae Invitae Combined Immunodeficiency (CID) Panel that also includes the following genes: STK4 TAPBP TNFRSF4 CD27 CD40LG ZAP70 CARD11 CD3G CD8A LRBA

More info about this panel

MALT1 Panel

United States.

By Fulgent Genetics Fulgent Genetics

This panel specifically test the MALT1 gene.

More info about this panel

Primary Immunodeficiency Panel Panel

Finland.

By Blueprint Genetics Primary Immunodeficiency Panel that also includes the following genes: RMRP RORC CFB BLM SH2D1A SLC7A7 SMARCAL1 SMARCD2 SRP72 BTK

More info about this panel

Severe Combined Immunodeficiency Panel Panel

Finland.

By Blueprint Genetics Severe Combined Immunodeficiency Panel that also includes the following genes: RMRP BLM SH2D1A SMARCAL1 STAT1 STAT2 STAT3 STAT5B STIM1 STK4

More info about this panel

FoundationOne® Heme Panel

United States.

By Foundation Medicine, Inc. FoundationOne® Heme that also includes the following genes: BCL6 BCL7A ROS1 RUNX1 BLM SDHA SDHB SDHC SDHD SF3B1

More info about this panel

Caris MI TumorSeek 592-Gene NGS Panel Panel

United States.

By Caris Life Sciences Caris MI TumorSeek 592-Gene NGS Panel that also includes the following genes: BCL6 BCL7A BCL9 BCR ROS1 RPL10 RPL22 RPL5 RPN1 RUNX1

More info about this panel

Tempus xT assay Panel

United States.

By Tempus Labs, Inc. Tempus xT assay that also includes the following genes: BCL6 RIT1 BCL7A BCR ROS1 RPL5 RPS15 RPS6KB1 RUNX1 RXRA

More info about this panel

Tempus xO assay Panel

United States.

By Tempus Labs, Inc. Tempus xO assay that also includes the following genes: BCL6 RHEB RIPK1 RIPK2 RIPK3 RIT1 BCL7A BCL9 BCR ROBO2

More info about this panel


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